As a pharmacist and clinical pharmacologist, I truly have to commend you for this video. You nailed all the fundamentals an average person should know. The amount of study required to achieve this result must have been immense. Well done, once again! 👏
@@Matthias_Fischer I'm not a native English speaker, but as far as I know the pronoun YOU may refer to one person as well as many persons. I don't doubt that Sabine may have a team of collaborates, but that doesn't change the fact that a lot of work has to be done to determine what must stay in and what must be left out of a short video, when talking about a subject with tons of literature that isn't Sabine's field of expertise. In addition, I assume you don't doubt Sabine's direct involvement in the presentation of the video, which is, as always, outstanding. I really can't get my mind around the reasons for attacking comments that praise the hard work of people, who offer high quality content free of charge. Kind regards
Hi Alexander. What should someone take for pain from pancreatic cancer? E.g. the person is taking paracetamol, tramadol and codeine. The only one with real effectiveness is paracetamol, but 8 in 24 hour period, separated by 4-6 hours each is not enough. Is there anyway to deal with this? Please do let me know, send me a message as it's listed on my profile I think and I'll go into more detail.
@@emar779 I'm not trying to dodge your question, but it would be very irresponsible and probably unethical to offer medical advice over the comment section of RU-vid. I'm sure - since there is a diagnosis - that a physician is already handling the situation and, therefore, assuming the responsibility of treatment. I hope everything works out well.
@@SAVVALEX Just asking for things to look into that laymen like me don't have access to. Docs run on their own schedules and pain for loved ones does not care for those schedules.
It doesn't get more German than not getting a joke an English person makes, then arguing about the factual accuracy of the joke with him and then preparing and giving a 20 minute public lecture about the general topic of the joke. Grüße.
As a PhD studying chronic pain, I have to say this video is really good! It would have also been interesting for you to cover how taking ibuprofen + paracetamol together is more effective than taking double of either one.
Yes but under doctor direction. A few years ago fractured my wrist. Rather than prescribe pain killers the doctor told me to take a specific combination of advil/tylonol/aspirin. Worked very well and only had to take for a few days.
Be careful of Ibuprofen though. It worsen tinnitus, and may actually help cause tinnitus. You do NOT want chronic tinnitus. So, take the minimum ibuprofen you need.
No please no, here were provided much of High Quality Physics stuff an its getting worse from Video to Video. Sehr geehrte Frau Hossenfelder nicht dass sie andere Themen nicht sehr klar und verständlich ausdrücken. Aber Physik ist neben Mathematik die Königsdisziplin, wer über Bienen, Gender-Gaga oder irgendwelche Pharmapillen Bescheid wissen will soll sich einen solchen RU-vidr/in suchen.
@@saschahofer413 "Dear Mrs. Hossenfelder not that you do not express other topics very clearly and understandably. But physics is the supreme discipline next to mathematics, if you want to know about bees, gender gaga or any pharmaceutical pills, you should look for such a RU-vidr."
@@saschahofer413 Hahaha. You mean: "Chère Mme Hossenfelder pas que vous n'exprimez pas d'autres sujets très clairement et de manière compréhensible. Mais la physique est la discipline suprême à côté des mathématiques, si vous voulez en savoir plus sur les abeilles, le gender gaga ou les pilules pharmaceutiques, vous devriez chercher un tel RU-vidr." (Obviously no credit to me -- it's google translate.)
Pharmacology and microbiology are absolutely fascinating subjects. The science behind analgesics is particularly interesting. It’s also interesting what we don’t know. As you learn more about the subject you realize that much of what we “know” about microbiology and pharmacology is theoretical. We have strong theories about how some of this works but they are still theories. We cannot fully confirm or deny them. I understand that we have theories about cosmology and quantum mechanics that we cannot confirm or deny. They involve things that take place on a massive scale, or a subatomic one and they can be rare and/or remote from us. The fact that there is so much about our own bodies that we don’t know is much stranger to me. I understand why but it still seems strange.
@@SabineHossenfelder There is one entire course at 3rd grade of biology that is mostly about how the nervous system receives and creates information (Animal Physiology part I), and that's on 3rd grade, after having had courses on how the membrane receptors work (Celular Biology in 2nd grade) and on the nature of the different molecules that activate those receptors (Biochemistry I, also in 2nd grade). So, it's basically end of degree stuff, and you got exactly right not only what the facts are, but also the important parts about those facts.
It would take a physicist to remind us that cocaine ran wall street in the '80s. Your sense of human is as incredible as your ability to explain science logically, coherently, and intelligently. THANK YOU.
@@zam6877 You are correct. I was thinking of Einstein (yeah that guy again) who did have a sense of human and a very strong sense of social justice. But I did mean humor. Which is also sadly lacking in the US.
Yes a very informative and entertaining video and funny to boot.. As for cocaine and Wall Street, hubris personified...recent tests found this awful drug all over Britain's Houses of Parliament, which explains so much of the deceit and bombast and inflated egos that consuming it entails. I speak from bitter personal and see all the indications.
Great video, thank you. And also a sponsor I can get 100% behind. Tried them out with students and not only do the experiments always work (contrary to several other science experimental kits) but you can do each experiment twice. Also, the results are generally visually impressive.
As someone who has ignored pains throughout my life yet now has accept chronic pain caused by arthritis and, possibly, old age, this video could not have come at a more appropriate time. I have discovered that many prescription opiates do not work well on joint deterioration/friction etc. While diclofenac and similar ketoprofen, ibuprofen etc do. You explained it all very well enabling even my comprehension of some salient points to be satisfied. Great informative video. Thank you. Love the suntan! Estonia has been very hot too!
I have similarly ignored pains throughout my life, and I had quite a bit of joint pain, but several years ago I stopped consuming any and all dairy products and the joint pain essentially ended, and to a small degree the damage has been reversed. It’s never to late to make healthy changes to one’s diet!
You might look into "wild lettuce". It's a weed that's more or less common all over the world except really dry areas. A guy named Mike Reed has a bunch of videos on RU-vid about how to use it for pain relief. He uses it for arthritis and joint pain. Good to know, in case pharmacies are ever closed or out of stock from supply chain issues etc...
If you had asked me last week what Estonia was, I would have said it was an enzyme, hormone or something. (Also, and totally not PC: how do you make a hormone? Don't pay her!)
I researched the different types of painkillers a lot when I was taking them regularly. After I changed my diet and cut out bread, sugar, almost all carbs, and started drinking a LOT of water, I don't have pain anymore unless I over exert. It's amazing what diet can do.
Congrats on your success! The saying "you are what you eat" is so true. So for example, if you eat foods that promote inflammation, you're going to suffer. Heavily processed foods with lots of carbs are highly inflammatory.
Yes! After I cut all dairy products from my diet the joint pain I felt every morning when waking up (that I thought was simply part of life) all went away. I tell people to stop consuming dairy, your body will thank you (and so will the cows!)
I appreciate the concern, but it's not a sunburn, I just tan quickly. Having said that, I noticed too late I was showing off my tan lines. So, well, guess I'll have to either wear this top less or more often in the summer.
I think I'll go with "it's magic". When I was a kid I was scared of the dentist. They gave me a sedative, that made it much worse. Somewhere along the way I realised that the treatment itself it wasn't actually particularly painful, the main component was fear of pain. Once I could understand what was being done and why, and what pains to expect, it ceased to be a problem, kind of like digging a splinter out of your finger with a needle - it hurts but you don't care because you know it will feel better afterwards. That skill became incredibly useful for the rest of my life.
Yes, this also applies to needle injection for vaccines and other medication. I used to get allergy shots when I was young and I learned how to ignore the sort pain, knowing what is going to happen lets me relax and the pain is less.
Yes, I do not mind my dentist, he has a great chairside manner, and he works to minimise pain at all steps. Simplest thing he does is put a small amount of the injectable lidocaine onto the gum first at the site, and wait a minute, looking at the rest of your mouth at the same time, then going in, putting a small amount in the now numb area, and then another minute of waiting, then finally the full dose. You feel nothing at all, which helps as I am insensitive to the local, so the regular dose normally means I do feel pain, but it is manageable for the duration. Fun thing about the 'caines is that they sublimate, or at least that is what they say in the police evidence room, when the amount they show on trial is half the amount registered at the bust.
@@steveboverie9432 Who does the injection also is the thing, I learnt from a hard as nails registered nurse just how to administer injections, because she would swab the area, then get ready with the needle, and tap the area a few times with the swab, to get your skin and nerves used to sudden taps, and then slip the needle in instead. You would not notice it. She almost always was the one doing the pediatric work as well, because she would not cause any sudden pain to the infants and children, so they would not cry, and thus not stress the rest of the children in the line out either. Plus she always had a big bottle of sweets, that she gave to them afterwards, as reward. But i did see her inflict needed pain on some, giving them a teaching reminder.
@@steveboverie9432 That too. I was in a road accident when I was 11, and had to have daily shots for a week. About halfway though the nurse told me, if you relax the muscle in your arm, the needle won't hurt. She was right. Why did no-one think to tell me that beforehand?
very good. as i was laying here with extreme back pain i got comfortable and watched your video. i realized my pain level had decreased dramatically and wondered if i had somehow found a good position to lay in which was partly true or was it that my brain was distracted by being interested in what you had to say. very interesting, thank you.
Get THE WAY OUT by Dr Alan Gordon.... It's invaluable for dealing with pain, as it's all about perception! I was part of the highly successful study in the book, and almost everyone saw immense benefits, most were completely pain free by the end.... No medication needed, just education!
@@MattAngiono well, when you have pinched nerves and herniated disc and degenerative disk disease as well as arthritis, diabetes, carpol tunnel, migraines, multiple bone spurs, everyday is full of pain.
@@kinggzz well, I wouldn't want to make promises, but that's exactly what I thought before coming across this stuff. The truth is that the body can heal, and even "pinched" nerves or slipped disks, or whatever kind of issue you might be having is still being processed by the brain. And if you can recalibrate the signal, the pain can go away. It's not like I'm invested in this, but it really did work for me, and I know how agonizing it can be to have chronic pain. Just try the book, keep an open mind, and see if you can reprogram the neuropathways that are stuck in pain mode. Like any other pattern in the brain, these things get stuck and stagnant. Some of the people in the study described in the book, which I was one of, had terrible seemingly incurable pain, decades of it, until we met Dr Gordon. Just give it a try and see what happens! I'm only spending time commenting here to try and help because I know the misty all too well
@@MattAngiono i assure you that if it were possible to touch another person and transfer my pains listed above and my 239 kidney stones, and my diabetic neuropathy as well as the bone spurs in my hip sockets, THAT PERDON WOULD SCREAM IN AGONY AND FALL ON THE FLOOR passed out from the shear agony. so my brain does help mask/ignore the pain but it does not fix the problems. thank you for the conversation. peace to you and your family.
@@kinggzz how about the Buddhist monk who set himself on fire? I'm pretty sure that would be worse and he didn't even make a face. I am only trying to help. You can check out a cheap book with an open mind or continue to pay who knows how much for meds that don't sound like they are working. What have you got to lose? Anyways, I'm not arguing, just suggesting what worked for literally every person in the study, one woman even had scoliosis and healed it. But it's totally up to you..... ✌️
“...though this risk also exists.” Favorite line. Listening to music can help you ignore pain. But what really does it for me is making music. It has been my chief way of dealing with gout pain when ibuprofen wasn't enough. Thankfully, though, my gout symptoms went away when I switched to low carb diet. Was this episode edited on a plane or similarly noisy environment? There are numerous awkward edit points - clicks, caught breaths, and so on. Great content, though, as usual.
suggestion (as I had acute gout in the little finger once) - avoid high levels of purines (type of amino acid) in food, eg offal like kidney. Also increase vitamin C and take joint support supplements containing chondroitin and MSM
@@MyMy-tv7fd , mine is chronic, and over the years, I’ve cut out red meat, shellfish, and a lot of other high purine foods. But symptoms kept returning anyway until I started intermittent fasting and cut way back on potatoes and white rice. Pain free for weeks now. Dr. Berg on yt explains why.
Try adding Youngevity's 90 for Life to your life and wow. I'm off my massive doses of all meds and almost completely off my opioids that I've been on since 2003. Thank God for Dr. Joel Wallach! But he's not as sexy as Dr. Sabine. lol
OMG you've outdone yourself with the humour in this one! I'm managing to still pay attention and learn something, but I'm laughing so hard that it's making it difficult! Thank you to everyone who makes these videos -- so educational, so entertaining!
I had a injury and received iv morphine. for two hours I had no worries in the world, I just floated on a cloud. Occasionally I think about how it would be nice to have it again. Now I understand why addiction is so powerful.
Not every one has that experience; for me, it reduced pain but had no more effect then aspirin. So, I was lost why people liked it - had it twice (two different surgery's) and no difference. Ditto codeine
This was incredibly helpful, I had bariatric surgery recently and was told I can basically never take NSAIDs again, but they didn't really explain well why, except that it would increase ulcer risk. Understanding the mechanics behind it is really interesting and makes a ton of sense now!
If you find you're struggling with pain after you've healed, check out the book THE WAY OUT, by Dr Alan Gordon... It solved everything for me once I had the knowledge!
The clip of Hawking running over Cox as an analogy for the cox receptors just blew my mind! 🤯🤯🤯 I am now convinced Sabine should be supreme ruler of the European Union!
Your best video yet Sabine! I even watched through the ad!!! Why? I think it was because you were learning about the subject as much as the viewers. I encourage you to please continue this in future videos. 👍👍
There is also acupuncture. I have once used it as acupressure to have a tooth removed at the hospital otherwise they had to wrestle me down by a couple of very strong persons because I can fly out of the window only by thinking about having a tooth pulled out. Total panic here but not using only two pressure points. The first one was Pe8 and the second I forgot.
I hate to tell you this. But acupuncture is all based on pre-science magic. No two acupuncture practitioners use the same pressure points or can even point to them being in the same place.
I had both hands covered in 2nd degree burns, the pain was about as bad as you can imagine. When I got to hospital, nurses applied a silver-based cream, and almost instantly the pain went from 110% to 1%. The mechanism behind it has yet to be studied though.
Silvadene cream!!! That stuff is awesome. I ended up with 2nd and 3rd degree burns on my foot (long story, me being barefoot and a grease fire in the kitchen). After getting it cleaned up, I was given that cream. Like you said, from 110% to 1%. That stuff is amazing.
The mechanism is very well understood. Burns are painful because neurons are exposed. Covering them reduces pain. Silverdene controls bacteria that just loves burns - people with burns mostly die of infection.
@@allangibson2408 I don't think that would explain my experience. By the time I got to hospital it was already blistering. The outer skin unbroken, had died and had separated from the skin underneath. I had a small (square inch) patch that actually had skin broken, but that was 3rd degree and was completely painless already. I really doubt any living neurons were ever in contact with the cream.
@@n-steam Third degree burns are painless because the nerve ends are destroyed totally. Second degree burns are painful because the nerve ends are exposed to air (which was why butter was traditionally applied to relieve pain - it unfortunately also accelerated bacterial growth).
@@allangibson2408 Yeah, I know about third degree burns. Experiencing them makes you want to read up on them. My point was about the blistering. The skin is separated. There's fluid between the layers of skin. I had blisters the size of each finger, 4 on each palm. Nerves on the exposed skin have no way to pass their signals through the blister.
Fun fact: Acetaminophen and Paracetamol both come from the full generic name for the drug: Paracetaminophenol 🙃 Also - Heroine was just the brand name for Diamorphine Hydrochloride which is still available on Prescription in most countries 🙃
Third time this week I have seen that clip of Hawking running over Cox with his wheel chair. Still cracks me up every time. Also: A good treatment for sunburn is topical procaine. Just thought of that for some reason.
Excellent explanation about how these painkillers work, what their downsides are, and how these drugs compare to each other. I haven't seen tons of videos about painkillers, but I'm pretty sure it would be hard or impossible to find one as concise yet informative as this one!
RE: Hypnosis I went through some training as a Hypnotherapist, and I can tell you that there is certainly something there. In one student-student exercise, my fellow student forgot our key intro phrase (something like "You may choose to remember any part of this experience at any time."). After sitting there for a bit, I asked her if she wanted me to go first. She blinked, and then explained that we had already done the exercise. In the end, I did not feel comfortable wielding that much power over another person.
I have allergic reaction to many drugs including some pain killers. I don't usually take pain killers except when I went into a surgery. When I was younger when I was in pain, I taught myself to think the pain away. I guess it was somewhat akin to meditation. I think I am more sensitive to pain now than when I was younger.
Same here. I was curious if someone mention this “self-induced Somatic Deamplification phenomena”. From my own experience, It’s something that our brain is capable of and can be trained (or should I say fooled?). Kind of magic actually. ;)
Knew a woman years ago who was taught , by a professor at UBC to block her chronic pain through hypnosis . Her husband said she became so good at it that she could immediately stop any pain -stubbed toe or kitchen accident . The nature of hypnosis would indeed make a great video. )
5:34 "Magic" 😆 I love when you do that Sabine. You talk at great length about something interesting and suddenly a joke appears. Bravo. By the way, I'm a former military medic so I have a slightly professional angle to this subject.
Did anyone else notice the two video lights reflecting in Sabine's eyes giving the seldom seen effect of two bright lights reflecting in her eye's. Good educational video, Sabine Thank you
As a retired health care professional, I found your video about pain very interesting. It would be good if you could do a video about the benefits of "medical hypnosis" as opposed to the theatrical hypnosis that most people are familiar with. 👍👍😉😉
Your video today was especially poignant, as I'm trying to wean myself off of opioids after over three decades of treatment for chronic pain. I won't go into the details of why I'm getting off of them, but I was told I would no longer be treated at my pain clinic (after being a patient since 2005). Your link about this will be most helpful. Thanks for all you do.
Thanks Sabine for this vid, it was informative. I have been on opioids for several years due to cancer and am starting this month on a 10% MED (Morphine Equivalent Dose) reduction. Nice to know it's the accepted method. FWIW I did not have good results with Cannabis.
Hope your cancer has been taken care of! Coming off opioids is no fun... :( I hate unsolicited medical advice, but I will just say that kratom helped me quit opioids incredibly fast, with no withdrawal.
You've got to get the book THE WAY OUT by Dr Alan Gordon! It's the best tool for chronic pain, as perception is everything. I can tell you from personal experience, it really works! I was actually in the study the book is based on and it was very successful, more so than anyone expected, even the doctors involved!
Wow! That explains why aspirin was a preferred migraine medication to others, it just took a lot of the pain receptors out of commission; my migraines can have aftershocks and follow up migraines, so an abort that acts as a preventative is important. Very cool, but good reason to be wary of it, I have found other medications to manage migraine but I will have a new respect for aspirin
I love that you branch out from physics now and again because the quality of the information is still excellent. I studied medicine at uni and after doing pharmacology I am in the same boat as your friend; not many drugs make me nervous but paracetamol does. If you take a couple of pills more than you're supposed to each day, over a period of time, you can have killed yourself and wont know about it until your liver completely shuts down so without a transplant you're gone. I had toothache recently and was taking ibuprofen, codeine and paracetamol; I made sure to write down what I took and when so I definitely didn't overdose on paracetamol. It's scary stuff.
Dr. H. Can't thank you enough for this. So clear, and after several viewings I think I will really understand my pain/pain relief battle. I know your a phycist (I'm a subscriber) but I wonder if you might br8ng your intelligence and clarity to tinnitus. Thanks.
I second this. My mom has tinnitus and all the doctors have done so far is recommend white noise apps. I wonder how much we know about it and how long it's gonna take to develop an effective treatment.
You must get the book THE WAY OUT by Dr Alan Gordon! You don't have to suffer, if you get the right knowledge. Worked for me after chronic suffering for years
This is by far the most educational yet entertaining channel on RU-vid that I've seen yet. Sabine I just love your explanations on topics not only pertaining to physics but also the world at large. This channel is extremely invaluble to me as I am a total dunse when it comes to math. Thank you for everything.
Sabine, Pain is only a part of the flu I currently have. (Got tested for COVID and I am negative.) I am curious about how decongestants, expectorants, and cough suppressants work on a molecular level now. 😅
i have been suffering from severe chronic migraines 3-5 days a week since the age of 12 yrs i really enjoyed your presentation and learned a few interesting things thank you c noel canada
I think a person's pain response varies quite a lot from person to person and that difference probably determines both how effective and addictive pain killers are. I would not be surprised if more pain sensitive people have more phycological pain as well because they are more rightfully fearful of pain. I would bet those people are also more likely to become addicted to painkillers because they have more of those receptor thingies. ...Myself, I'm person who has a very low pain response. And no history of drug abuse. I've injured myself many times and though having been prescribed them I've only ever taken a single pill of a prescribed pain killer because I didn't think I needed it and honestly it didn't seem to have any effect on me. Same goes with over the counter stuff. I often go years without even taking an aspirin. Recently while barefoot I banged my foot on the leg of a couch so hard my toe began to bleed. The leg was round and smooth so couldn't understand what cut me. It was a fairly large and deep looking cut. It didn't hurt that much, but it also wouldn't stop bleeding so I went to the emergency room figuring I needed stitches. There I was asked first by the nurse, then the nurse practitioner, then the doctor I'd say a good 6 or 7 times what my pain level was using their little pain chart that ranged from 1 to 10, 10 being the end of the world. I answered it was a 1 or at best a 2. The doctor ask how I did it, looked at it some more then said he needed to do an Xray. I bucked cuz I didn't want a dose of radiation just so he could pad the bill. That's when he told me it was a compound fracture. That my bone is what had caused the cut and he needed see what the break looked like to be sure it was okay to just stitch the toe back up. He then also remarked he was surprised and maybe a little concerned I didn't feel more pain. I believe my high pain threshold is due first not feeling pain as strongly as most people and because of that lack of feeling my brain also hasn't learned to be as afraid of pain as some people.
Thank you Sabine, I watch your videos as often as I can. I sometimes struggle with the math and concepts, but enjoy them all the same. Your demeaner and steady even pace often fills in the blanks.
Your videos are always the best I do receive a notification each time you post a new video.we will have regrets for things we did not participate in. Investment should always be on any Creative man's heart for success in life and I'll advise you do little glimpse of that on your video*
Mr Michael Taylor is the right person to start trading cryptocurrency with.. he knows he's way around the crypto world.. he has been helping me increase my investment every day for over months..
I had a nerve ablation done to my feet (a nerve near the tibia killed by electric pulses). I have substantially less pain in my ankles now. I'm happy with it. (FD: Born with spina bifida, lots of operations, no cartilage in my ankles etc. etc.) I am now being weaned off my pain killers.
I have done martial arts from the age of six this has given me stupidly high bone density, the total inability to bruise, and a very useful ability to forget pain, it still hurts but I can sort of put it to one side so to speak. If it is an ongoing pain that is.
Sabine, I loved your English jokes, and seriously, I appreciate very much your science about the physiology of pain. I spent two years in Germany as a post doc fellow in a Biochem lab (I'm Brazilian) and it was amazing, professionally and as a life experience. Your accurate explanations reminded me the group discussions we had every week. I've already subscribed to your channel, Danke Schön!
I love all your contributions even when not directly your field of expertise! Please do never say that you are just a physicist, this is false modesty.We all know that physicists due to their scientific education simply know almost everything or they can explain many things even outside their field. On top of that, they all are very good in math and thus logics.
I vaguely remember that there are two paracetamol molecules a levo and a dextro, one is the version in everyday use and the other not because its really hard and expensive to manufacture, but that version doesn't cause overdoses.
N-methyl-D-aspartate (aka NMDA) antagonists (eg: ketamine) can also act as painkillers. I hear they work quite well (acting kind of like a local anaesthetic - numbing everything - but over the whole body), with the unfortunate downside of making one feel *very* loopy. Well, or in high enough doses, pass out - they're also known as dissociative anaesthetics. Still, I'm very surprised they're not used, at least in palliative end-of-life care. I don't think NMDA antagonists are necessarily anywhere near as addictive as opioids (although I could be wrong), and apparently ketamine in particular is being trialled as a fast-acting antidepressant so I could see multiple potential benefits, at very least in end-of-life patients.
Usually I don't like advertisements in the video(Who does?). But this time I have to support Frau Hossenfelder's ad for MEL Science. I don't know MEL Science at all. Once, many years ago I was an East German boy who had a young aunt who had had no own family yet then. From her first self earned wage she bought a chemistry experimental kit. I was way to young for it then and my mother immediately removed the hydrochloric and nitric acids as she feared that I could do me a harm. But as she had no chemical knowledges she had left caustic soda, ammonia and such weird things like copper sulphate, so that I could make some of the fine experiments, however had not understood them then. To cut it short at least: This was one of the very decisive gifts of my life I suppose. It made me very curious to learn a lot. I became interested the in everything from chemistry to zoology, electronics. Finally I became a banker.😁 But this very broad interest remained all my life and has stretched out to philosophy, sociology and genetics. If I had young children today I'd make such gifts to them.
About the only thing Sabine left out was the in sometimes beneficial, sometimes harmful, blood thinning effect of aspirin. Low dose aspirin 81mg-quarter of an normal aspirin pill) is often recommended to reduce risk of blood clots and cardiovascular events. Do other NSAID's have this effect?
Your pain (relief) presentation was masterful and wonderfully concise. I never finished my Ph.D. thesis on the role of acupuncture in the management of chronic pain, buy my discomfort at revisiting pain management was moderated by the audio-analgesia you generated. Dass ich in Ulm an der Donau geboren bin, ist relativ nebensächlich.
Savine, I could watch your videos forever thank you for the gift of knowledge you are amazing and I love how you explain it. Keep up the good work we love you from Arizona
On sound and pain relief- an aquaintence of mine is a music therapist at a children’s hospital. She uses music to help with pain management for burn victim’s dressing changes and difficult line placements etc. Very interesting!
I have suffered from chronic pain since 2017. Opioids for me at least work in a somewhat different manner. They don’t actually take the pain away but make it so that you don’t care as much about it. It’s still there but just a lower priority in your mind.
Used to do casual convection experiments with kids, using homogenized milk, food dyes and dish soap. Dyes and milk mixed then soap emulsifies the fat and there's turbulence. Pretty colours all swirling around.
Great video, fascinating and v informative. That stat at the beginning floored me, I simply can't fathom how almost anyone _wouldn't_ feel some kind of pain on a _daily_ basis, and I'm not talking about all the kinds of chronic pain so many of us suffer. Whether something akin to stubbing your toe/swinging your hand/arm/elbow into something, moving/bending too fast or far, getting a hair caught in something, bumping your head, cracking a knuckle, drinking/eating something too hot, picking your nose a little too intently, jamming a finger into something, touching your vehicle or anything metal out in the sun, fighting with your cat, hot gluing, lighting or inhaling from your bong/ciggie/e-ciggie/joint/one-hitter too hard, paper cut, too much salsa/eating a hot pepper/hot mustard/wasabi, or god I could go on for a long time listing just some of the myriad ways pain gets inflicted on us in the most basic daily activities. How does one go for 3 months without experiencing any pain? Interesting bit of info--long term use of heroin really does little damage to your body, the serious degradation usually associated with addicts is due to the difficulties of living as an addict. I usually get massive blowback when making that claim but never anything relevant. I got that info from the excellent call in show Dr Dean Odell used to do, he was always very focused on the science side of issues.
@@SabineHossenfelder the book VRx by Dr. Brennan Spiegel goes into a lot more detail if youre interested I highly recommend it. Im in VR medicine myself and happy to comment further on the topic. 😊
Wow... that was excellent! I think you explained that better then most health experts could. FYI, I was at a science exposition a few years ago the University of British Columbia, Applied Sciences Faculty, where the were demonstrating Virtual Reality research for health purposes. One area of research, they would have chronic pain sufferers put on VR headsets, and use the immersive VR experience to distract the brain from pain.
Please, more pain videos. I suffer with severe low lumbar back pain and take Tramadol which helps. I need surgery to fuse L4 L5 and S1 but some new technologies may soon reduce the need for fusion by artificially replacing the disc between the vertebra with a chemical which simulates the disk, It's called Hydrafil and is in trials now I have had a bad back of over 20 years and I do NOT want to take opioids since they make me feel cloudy and unable to think clearly. You may not be a medical doc but this video has helped as muh as the advice I have received from my docs. Science is science Thanks
One of my favorites, that isn't actually a pain medication: Metamizole (sold as novainsuflon, novalgin). I regularly have (often stress induced) digestion problems. It does wonders against that. It also helped recently when I had tonsillitis (that HURTS). Again it isn't really a pain med, and has some side effects, but in certain situation it makes an unbearable day into a manageable day.
