Hi....in the video at around 9:44 minutes you mistakenly said that Alpha2 receptors primarily located upon "Pre" synaptic nerve terminals......Whereas actually THEY SITUATE ON "POST"SYNAPTIC NERVE TERMINALS.....as you rightly showed and teach in the diagram...... (by the way superb video and I happily enjoyed learning through your videos)
Glad you liked the video and thank you for the comment! The video is correct in that Alpha-2 receptors are located on presynaptic nerve terminals. Make sure not to confuse the terms "preganglionic and postganglionic neurons" with "presynaptic and postsynaptic neurons". They're not the same thing. Remember a synapse is simply the junction. A presynaptic neuron sends information toward a synapse, and the alpha-2 receptors are located on the nerve terminal before the synapse (the presynaptic neuron). In other words, the video shows presynaptic alpha-2 receptors on the postganglionic nerve terminals. Hope that helps! 🙏🏻
I don't understand in beta 2 video u said urination decrease when smooth muscle relax...here you said when the case of alpha 1 smooth muscle of urinary system get contract.. urination will decrease Explain why?
Great question! Here is the simple answer. It's all about the location of the beta-2 and alpha-1 receptors on the bladder. The beta-2 receptors are located on the bladder wall, so when they are activated it leads to smooth muscle relaxation which will lead to decreased urination (as the bladder is not contracting). The alpha-1 receptors are located on the urethral sphincter, so when they are activated it leads to smooth muscle contraction which will cause contraction of the sphincter which will prevent urine from exiting the bladder. So we can see how alpha-1 urethral sphincter constriction combined with the beta-2 bladder wall relaxation will synergistically cause urinary retention and decreased urination. Hope that helps! 🙏🏻
![Alpha Adrenergic Receptor Types, Location, and Function [Alpha 1 and Alpha 2 Mechanism of Action]](/img/logo.svg){kind=logo}
