Haha Moof University! Love it! Thanks for the vid. I love the end where you squeeze in you're a tutor haha. I'm attending UCI right now finishing up my bioengineering degree. Super fun.
hello, i just wanna bring one point, is that "A" and "H" exons must be present in both mature mRNA and they are always present, because they represent the start and stop codons.
Okay understandable, but can exons be set up in different sequence than they were in pre - mRNA? For example in pre-mRna we have the order like: 1234 exons, but in mRNA we are going to get 1423 exons?
Erza Fernandes Interesting point. I've seen a variety of diagrams, and there's a split. Some diagrams indicate that the 3' poly-A tail is added before introns are spliced out, and others show the 3' poly-A tail being added after the introns are spliced out. Thanks for mentioning this!
That's not true. Please provide sources to back up this claim. The pre mRNA is capped with the 3' poly-A tail and 5' cap before the introns are spliced out.
blackfoxmp5 That's what I've learned, and that's what I describe in the video, but there are some diagrams that I've seen here and there from a few Google searches that don't go along with that. Then again, I really don't know about the accuracy of those diagrams.
+Moof University +Moof University the 3' poly-A tail and 5' cap needs to be added to the mRNA to inhibits its hydrolysis by other enzymes , so they are present before the splicing actions occur
Great video. From my textbook, there are multiple 3' cleavage site. So after cleavage at any of the 3' cleavage site to produce alternative splicing, then polyadenylation can occur.
This would have been helpful had you used the codons. The A U C G and yeah. those. Cuae i swear to god our professor be giving out workshitsss and expecting us to already know the answer
hi I was hoping you could help me, how does alternative splicing leads to a one amino acid change in protein sequence on the same gene, with all the exons being transcribed.
