Just wanted to clarify for patient #5, question 2. The peak and trough is normal. There's no need to dose adjust. The trough is on the lower end but all we can do is monitor the patient closely for improvement in their clinical presentation. Patient is at q8hrs currently so the frequency can't be increased hoping to increase the trough slightly. In clinical practice aminoglycosides are not normally dosed q6hrs. Hope this helps.
I was prescribed gentamicin for 6 weeks. My dose was everyday at 10pm. I don't recall peak and trough levels being monitored, perhaps peak and trough were measured once in that first week but in the remaining 5 weeks I only had blood samples taken every morning around 6 hours after my dose. No trough levels taken half hour before dose or peak levels after my 60 minute infusion. Is this normal? No dose was skipped until I refused my final dose due to symptoms. I'm left with irreversible damage to my vestibular system and vision.
