Anaphylactic shock | Circulatory System and Disease | NCLEX-RN | Khan Academy 

I'm 28 years old with deadly food allergies and I wish I'd learned earlier how anaphylaxis works, this video demystified it for me and made the threat a lot less scary, thanks!

I am a paramedic student and you just solidified my understanding of anaphylaxsis. Thank you so much. I was also confused about what actually happened, even after I got my EMT. THANK YOU!!

Aug 1 2021 was chilling outside trying to enjoy my turkey sandwich. All the sudden a yellow jacket bit my upper lip. Within 2 minutes I felt itchiness on my hands and feet. Rush into the house to jump into the shower hoping to feel better. Within 5 minutes after the sting I passed out on the bathroom floor. Don't know how long I was unconscious. Finally crawling into my bedroom looking for phone to call 911 while struggling to breathe and talk to a dispatcher while chocking to death. I was in and out of consciousness. In the meanwhile my bile was moving uncontrollably with stomach pain and nauseous. EMT finally arrived while I was trying to crawl back onto the toilet. Yep had full diarrhea while people stared at me pooping and passing out and failed down from the toilet. Weaken muscle laying on the floor with my own fece and all I've heard EMT saying there's something else going on. I struggled to breathe and scream no just bee!!!!!!! They literally had to drag me out the door into the ambulance and pumped benadryl epinephrine, steroids, hooked up on IVs and hurt fully clipped my gel nail to monitor my blood pressure on the way to the ER. Within 10 minutes from enjoying a Turkey sandwich in the backyard to fighting for my life in an ambulance. Closest to death I've ever experienced. Been perfectly healthy 51 years of my life and never thought I could be allergic to anything other than seasonal allergies. ER doctor confirmed it was anaphylactic shock and now having to carry epi pen with me at all times as the next insect bite will be deadly. Definitely going to make appointment to see an allergist for wasp Hornets and other infectious allergies. Bummer I'm such a nature lover now I have to be extremely careful. Bee sting venom affects your vital organs especially your lungs your heart and your bowel. Needless to say it was a shztty Sunday but thank God I'm still alive and want to go to the beach and travel around the world and dream of traveling to space before I pass this earth to the next life. Count your blessings and love your loved ones before it is too late. 😭🙏🧡

This is an absolutely fantastic video. I often feel that when writing about medical processes, many people would rather show off their knowledge rather than making it understandable. I really love that these videos make it so easy to understand!

my dad is going through this tonight and i am so thankful you’re explaining it so beautifully and making me feel better thank you always

Oh my gosh how amazing!!!!!!! Life saver.... absolutely loved this!!

As a CNA, a pre nursing student, and a mom with a 2 year old with an epipen THANK YOU. I needed this brush up

As usual, you of Khan Academy make everything so clear and easy to understand. It was funny to know at 33 which mechanism almost killed me for four times. Thanks.

dude, i love you thank you for making my life so much easier

Clearly and simply explained! Thank you!

thank you so much for this. you're a lifesaver.

Wow amazing and simple presentation! I just had an epi pen after having un diagnosed anaphylactic shock. Last year. It was Hades.

It's horrible. I was actually in anaphylactic shock. It happened so fast I couldn't believe it. I was barely moving air by the time paramedics arrived and in the ambulance I stopped breathing altogether. I thought his face was going to be the last thing I saw.

Thank you so much I was taking penicillin and then my legs became string beans and I went down fast. Luckily I had only taken part of the pill for some reason . I had taken penicillin before in the past and thought nothing of it. I started to pass out. My friend came into the room just then and I couldn't hear him and everything started to turn black and his face was a little circle. I laid there a while and then could hear and could see again. And waited till the paramedics came and took me to the hospital.

Thank you soo much !!!!!

Great video!!!! Thanks!

Love your channel! As a visual learner -& nurse, I truly appreciate the ease of learning and re-learning from you! Thanks so very much!!!!

Thank you for these videos.

I am getting ready to cover the chapter on Allergic reactions in my EMT class. This video helped me understand anaphylaxis some more.

thank you, I like this!!!!!!! easy explained

Thank you so much sir.

U guys are life saver. Makes things so easy to understand.

Can you guys at khan academy make videos starting from base on because im in eighth grade and they currently dont teach biology at school so i study it on my own i do this because i want to become a surgeon. I currently volunteer at a hospital 4 times a week so i feel that if you started from the beginning that would really help

Thanks alot ❤

easy to understand,

Great explanation

excellent. thanks sir

this help me a lot to understand what an emergency shock anaphylactic is

Thanks so Much this is super helpful: Quick question I understand that you cant have immunologic anaphylaxis on your first exposure as the immune system needs to be primed, but is it possible to have non-immunological anaphylaxis first exposure as the allergen directly acts on MAST cells and theres no need for IGE? Cheers!

Then how can get the reaction simply touching seafood? My reaction to seafood is definitely getting more sensitive as i age. I had a severe attack once and it instantly subsided after ingesting medication at the ER.

Really helpful... Great work✨

Thank you so much

My allergic reaction happened last year at summer camp. I got red itchy eyes and the eye drops didn’t work and mom made me have allergy medicine and it worked.

very well explained

thanx khan

I have just developed this and learning about this have made me be aware what I swallow

It's nice to also add (Since this is medicine) that there is an isotype switching error, since the b-cell "Should" produce IgG/M, but something goes wrong in communication between T-cell and B-cell, that makes the B-cell create IgE instead, which then attach to mastcell /Basophil

Thankyou Sir, very well explained ❤

Good knowledge thanks from Dr mahendar

These are very helpful, I just have one question. I thought the Leukotrines caused bronchoconstriction, is this incorrect?

May Allah bless you , Thank you sir :)

Went in to anaphylactic shock yesterday.

thank you for sharing that.....its happened twice to me, one in a very serious car crash and an allergic reaction to what my dentist numbed me with

Thanks u sir 👍

Very good explanation 👍

Wow I actually understood that to some degree and I'm an idiot,well done ,Thanks

Really GOOD 🙌

Once the body have been introduced to an allergen once, does the IgE for that allergen remain attached to mast cells? Or is it re released by memory B cells upon second exposure?

bunun cevirisini yapin sayin khan

Hop on the beat, Now I’m spazzing, Got ‘em shock, Like anaphylactic Ayyy

does epinephrine stop the leakiness of blood vessels?? i mean what should we give for leakiness .. plzz plzzzz reply

the way i see it if i had too choose between ventilating the patione with CPAP or BiPAP and giving them epinephrine i would reach for the epi pen first as that is also a treatment for maintaining the airway due to smooth muscle dilation, then pop them on ventilaion

One*

As I got older my tree nut allergies seemed to evolve from slight trouble breathing and puking to no trouble breathing and instead agonizing pain all throughout my entire body to the point where epinephrine injections have no effect. A lot of people can grow out of allergies as they grow older, but I was triggered multiple times, either through accident or on purpose due to some giant asshole who thought it would be a good idea to murder me. Though I wonder what the difference between peanuts and tree nuts are, because I can eat peanuts just fine.

Y does Vasodialation occur I allergic reactions? 😢

Isnt the C in ABC Conciouness ?

Given Henhouse huff of the

From what I see on other videos it seems that Anaphylaxis is autoimmune disease when It revolves around Certain foods such as apples,honey,etc. I want to know does the drugs that suppress the immune system can battle the Anaphylaxis?

this happened to me today

Bee Cells, ROFL

Hi all and pls help me out to understand the situation, I had gone for CT abdominal contrast iv , as dye inserted in my body I start feeling the dye travelling whole body and felt allergy like bee is biting whole body, i stand up and asks rediologist to stop immediately and fainted, after some time when I wake up I peed in my pant and Doctor told me we have given you CPR. Let me know how normal is this ? Can I live life normal and this will not happen again, how is my life expectancy, my all body vitals are ok ,I kept 1 day in hospital to check my vitals. Pls help me out it was shock or cardic arrest. This will definately give me idea what was happend to me actually. Will be appreciated. Thanks God bless everyone

Is this an actual school?

geez which cytokines do what? this isnt in depth enough for med school :(

What if you get hives all over but not have trouble breathing?

Great,but i hope it will be good for me with indonesia subtitle 😢

i get shortness of breath, dizziness (fainting) after eating, raw vegetables like carrot and cucumber, i don't get hives and other symptoms but i get sometimes choking sensation with weird fainting. Is this anaphylaxis?

Bruh I just ate shrimp and I'm getting a headache and itchy throat.

I have had 5 anaphylactic reactions and I’m only 6

I have the great anaphylaxis that can't be treated with an epi-pen. I will vomit and evacuate every ounce of fluid in my body until I die- yes, I will shit myself until I die. That is my curse. I last showed to the ER with a HR of 45 and a body temperature of 33.3 degrees. I didn't even know it was anaphylaxis but I knew I was dying.

can you die from it?? CUZ IM SEVERLY ALERGIC TO BEES WASPS TOMATOES ACIDS AND ALOT OF STUFF..

A peanut sat on a railway track It’s heart was all a’flutter A train came speeding Down the track TOOT TOOT Peanut Butter

👏👏👏👏👏👏👏👏👏👏👏👏

Anyone here after marcus veltri had this?

Just came here after eating 2 grapes that put me in hospital 😊

Study

Who is here for the ©0v!d injections?

Guys this is inaccurate. I’ll be uploading a video of how to correctly perform the procedure in 3 languages. Don’t trust this

F*ck me khan i love you so much... this helps me in med school...

Hi all and pls help me out to understand the situation, I had gone for CT abdominal contrast iv , as dye inserted in my body I start feeling the dye travelling whole body and felt allergy like bee is biting whole body, i stand up and asks rediologist to stop immediately and fainted, after some time when I wake up I peed in my pant and Doctor told me we have given you CPR. Let me know how normal is this ? Can I live life normal and this will not happen again, how is my life expectancy, my all body vitals are ok ,I kept 1 day in hospital to check my vitals. Pls help me out it was shock or cardic arrest. This will definately give me idea what was happend to me actually. Will be appreciated. Thanks God bless everyone