Thank you doctor for the wonderful explanation! You don't how much your explanations mean to struggling med studs like us, keep being an inspiration! :)
Many thanks, Doctor..Your assessments on every subject I've heard you lecture on, have been very informative, clear, and concise..Please continue these videos..
Thank you for a much better explanation than I was given when I was nine, and was told that the immune system acts like an army to fight off disease. I must have spent two or three hours trying to visualize my immune system fighting germs the way an real army does, and ended up so confused I decided that the doctor was either crazy, stupid or he missed a few important lectures in medical school.
I had an anaphylactic event once to a new medication and it was very scary! My lungs were so damaged, I was under the care of a pulmonologist for 6 months. He told me the mast cells were hanging around after the anaphylaxis and it was causing me to have ongoing shortness of breath. I carry an epi pen now everywhere I go!
my daughter has diagnosed IgE, fPIES and i had to help her with the suspected Histamine intolerance and or (Mast cell activation disorder), as there's no clinical help for the latter two issues in my experience, my question is as a mother who has researched immunology to try and help the two latter issues, is, can there be localised degranulation of mast cells, releasing histamines either all at once or on a slow released basis? That would not be resulting in ANA but most definitely a whole heap of uncomfortable symptoms? Do medical professional accept that can happen to a wide range of triggers such as medications, foods, chemicals and other environmental factors such as smoke, pollen, dust etc..? I would be really interested to know any of that plus more.
If we have no other equipment but an expired epi-pen (1 year expiry for example) is this still okay to use and better than nothing? Would it be unsafe and why? Or just not as efficient? Thank you.
Can anaphylaxis be related in anyway to the mrna vaccine? Asking for a friend that just had an attack out of the blue with all the symptoms and now needs an epipen
What is the difference between this massive allergic reaction and what they call a 'die-off' when, for instance, yeast cells are killed by some drug and release a neurotoxin making one feel very ill? We are told that 'die-off' is an expected common reaction when one tries to detoxify their body.
Probably that the chemical mediators being released are different substances. Unless yeast is expressing interlukens, heparin, platelet activating factor, or tryptase when it dies.
Thank you this helps. I had my first episode when I was using a shampoo body wash product gave me an allergic reaction which I ended up in ER. I had the IV treatment you stated adrenaline. I never had a experience like this I am 44 years old. The ER doctor stating I have Anaphylaxis. I want home and I still have episodes for 7 weeks. I have no insurance but going to a specialist. I freaking out and don't have an Epipen and don't know why I still have anaphylaxis I stop using the shampoo. So going to get tested an hoping it not an immunity issue. I am a female and I noticed also during my period it gets worse.
Dr Campbell, in patients ' safety and Public interest would an anaphylaxis kit and algorithm from resus be an advantage to have in wards? I noticed this gap and was wondering if i should highlight this? As a newly qualified nurse, Im unsure how to approach this. However, I am worried as searching for meds can increase mortality /morbidity. The epinephrine is in the crash trolley but the other items are either in the medication trolley. I wish for this to be a priority as sepsis trolley and hypoglycemic box.
Normally the resus trolly has adrenaline 1 in 10,000 for IV use, for anaphylaxis the 1 in 1,000 for IM use in more normally indicated. We don't want people giving adrenaline if it is not indicated of course, so if it was easily available there is a risk of inappropriate administration. I think the key is when you move to a new clinical area is to learn where the heck everything is kept.
