Beautifully presented, Dr Campbell. I thoroughly enjoy these short lectures because they expose me not only to medical situations but also to associated treatments and various drug names.
A very brief and detailed insight into anaphylactic reaction...I just learned anaphylaxis in emergency and this video had been very helpful in understanding the importance of adrenaline during these reactions.
@@Campbellteaching they will love this. Both are on school holidays.. but one has to attend compulsory exams this week... today Chemistry, tomorrow Physics and Biology.
Great explanation! Thank you! I have one question: does it means that Anaphylaxis will occurs when SECOND exposure to allergen was happened? For example: vaccination - is the first vaccination (even body is allergic to this vaccine or compounds) will NEVER cause anaphylaxis? Only second vaccination can cause anaphylaxis? Why I'm asking because I have some connection to Pharmacovigilance and case assessment and often we have the cases when after first vaccination anaphylaxis is reported (swelling, vascular disorders etc). Thank you in advance for your reply!
Excellent! I'm 61 and 10 years post menopausal. At 53 I went into anaphylactic shock for the first time to almonds, which I had eaten for years. Then 3 years later it happened again to peanuts, which I'd eaten for years. Then I had mast cell activation disorder for about 8 years until I ramped up my diet and transitioned to a whole food plant based lifestyle. I no longer have any type of mast cell disorder, which I'm grateful for...because for a long time by body reacted to anything with the smallest amount of histamine. I still cannot tolerate any type of nuts (never again almonds or peanuts!). I have some bronchial reactions even when trying to introduce small gradual amounts as in desensitizing and I have rashes to trace amounts of nut oils in lotions. So I have forever eliminated them. Can you explain the sudden "change"?
Thank you for this video. I appreciate your time. I don’t understand one thing. So these mast cells are in our body to defend against antigens. But here we see that chemicals inside the mast cells cause people to die. So in which scenario these mast cells can do their job successfully without a damage to the body?
What about type 2 to 4 hypersensitivity, I honestly like the way you lecture. You always touch every Conner of the things you lecture. Very understanding
I had Anaphylaxis reaction to Meningococcal vaccine long time ago which ended up getting epinephrine injection but I'm really concerned about getting any vaccine ever since. What would be the best procedure if i have to get the Covid-19 vaccines? Any particular test i need to do beforehand? Cheers.
There's no test beforehand. The two vaccines are different, but without knowing what specifically you were allergic to in the Meningococcal vaccine, it is hard to know if it won't happen again. The vaccines are different but may have the same ingredient in that you are allergic to. You will need to speak to your GP.
Hmm, I guess both are true, an antigen is anything recognised as foreign, and in the case of an allergen something is recognised as foreign which should not be recognised as foreign, rather it should be immunologically tolerated. So in allergy an allergen is recognised as an antigen.
