In this episode, we discuss the latest updates on CAR T-cell therapy in multiple myeloma, including the studies presented at ASCO and EHA 2023. Here are the show notes:
1. For a primer on CAR T-cell therapy, listen to our episode aired on July 22nd 2022 with Dr. Surbhi Sidana: share.transistor.fm/s/efc4acf9
2. RCTs of BCMA CAR T-cell Therapy in Early Relapsed Multiple Myeloma:
a) KarMMa-3 (ide-cel): pubmed.ncbi.nlm.nih.gov/36762...
b) CARTITUDE-4 (cilta-cel): pubmed.ncbi.nlm.nih.gov/37272...
3. Clinical trials of GPRC5D CAR T-cell therapy in multiple myeloma:
a) MCARH109 (MSKCC Trial): pubmed.ncbi.nlm.nih.gov/36170...
b) POLARIS Trial: pubmed.ncbi.nlm.nih.gov/36725...
3. Phase 1 UNIVERSAL trial of ALLO-715 in Multiple Myeloma:
pubmed.ncbi.nlm.nih.gov/36690...
4. Anti BCMA/CD19 CAR T-cells with IMiD maintenance therapy in myeloma:
pubmed.ncbi.nlm.nih.gov/36413...
16 июн 2023