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Beautiful 3-D Brain Scans Show Every Synapse | National Geographic 

National Geographic
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Ultrathin slices of mouse brains offer a mesmerizing look at how brain cells communicate at the tiniest scale. This research may offer clues about how the dance of our own synapses guides and animates us.
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PRODUCER: Shannon Sanders
ANIMATIONS AND 3-D RENDERINGS: Jason Treat, Kurt Mutchler, Bryan Christie, Joe Lertola, and the Harvard SEAS Connectome Group: Jeff Lichtman, Seymour Knowles-Barley, Narayanan Kasthuri, Verena Kaynig-Fittkau, Mike Roberts, Amelio Vázquez-Reina, Bjoern Andres, Daniel Berger, Thouis R. Jones, Eric Miller, Hanspeter Pfister, Sebastian Seung (MIT), Richard Schalek, Kenneth Hayworth, and Juan-Carlos Tapia
Beautiful 3-D Brain Scans Show Every Synapse | National Geographic
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National Geographic
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27 июл 2024

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Комментарии : 197   
@lunachickfringe5319
@lunachickfringe5319 3 года назад
Why would anyone give this a thumbs down? Fifty viewers who just couldn't grasp the idea? This is amazing and so incredible to me. Never quit learning.
@polymathpark
@polymathpark 2 года назад
people that didn't get hired by Nat Geo most likely
@alexandramcwilliams1241
@alexandramcwilliams1241 3 года назад
This made me tear up. It's just such a miracle and beautiful thing that we even exist the way that we do.
@Delta-Frost89
@Delta-Frost89 4 года назад
My brain wants to learn more about itself 🧠
@darkknight2407
@darkknight2407 3 года назад
you want to learn about your brain ! Real problem with science is it's very materialistic !
@jasonstauffert5559
@jasonstauffert5559 2 года назад
Exactly lol.
@williamjayaraj2244
@williamjayaraj2244 5 лет назад
A beautiful brain that creates a beautiful mind and yet it's function is beyond human understanding.
@Renu4UTube
@Renu4UTube 5 лет назад
William Jayaraj I love that! I'm stealing that! 😊
@beepbeep1836
@beepbeep1836 6 лет назад
So incredibly beautiful. Going to watch this with our school’s neuroscience club today!!!
@refink33
@refink33 10 лет назад
I love Science
@Tonywirthfilms
@Tonywirthfilms 6 лет назад
jajaaahahahaa
@OurNewestMember
@OurNewestMember 5 лет назад
No. I f-cking love science.
@Cheretruck_
@Cheretruck_ 3 года назад
Loving science is like cargo cult. Real science supporters don't praise this, they spend money and time for it + selfeducates.
@stunter_pt7506
@stunter_pt7506 2 года назад
Then u are in the wrong clip bruh... anotomy is way cooler
@pennybrewer4723
@pennybrewer4723 8 лет назад
beautiful on all levels. thank you.
@WheatBrewski
@WheatBrewski 2 года назад
That was so incredibly fascinating.
@Smashdreamm2
@Smashdreamm2 3 года назад
This is the coolest thing I've watched on YT. Thanks for posting this video!
@VtecSam
@VtecSam 10 лет назад
I want more!!
@unknown-bx4xn
@unknown-bx4xn 10 лет назад
Watching a video about the brain makes me want to develop more empathy.
@MustafaCihatCandan
@MustafaCihatCandan 7 лет назад
Beautiful !
@InquisitorShepard
@InquisitorShepard 10 лет назад
thats a whole lot better than the videos about the sasquach and other fiction things that ocasionally pop up on NG
@dianabarclay5644
@dianabarclay5644 3 года назад
Bigfoot is real
@ThePrayerful
@ThePrayerful Год назад
Fascinating information. I looked up these kinds of videos because I've suffered from migraines a very long time and just wanted to know something about how the brain works. I've had the privilege of working in the medical field and was able to s/w some neurologist of geneticist regarding alzhiemers since my grandmother and 4 of her siblings succumbed to it. Thank you for sharing this information.
@EliyaKostova
@EliyaKostova 10 лет назад
Amazing!
@farmvillepolice
@farmvillepolice 5 лет назад
You gotta see the wires at 1:08 seeing a brain like that blew my mind
@mustafacaglarr
@mustafacaglarr 10 лет назад
hey, good research man thanks from Turkey
@masaabsalh3114
@masaabsalh3114 4 месяца назад
It has been linked to intelligence: ApoE gene: thought to play a role in memory and learning. BDNF gene: Thought to play a role in brain development and cognitive functions. COMT gene: thought to play a role in information processing.
@marcosPRATA918
@marcosPRATA918 6 лет назад
Brilhante pesquisa.
@LiveSuperRichLife
@LiveSuperRichLife Год назад
Astounding details explored
@mmmk1616
@mmmk1616 7 лет назад
Cool, thanks Tim! :)
@h0lyrs422
@h0lyrs422 10 лет назад
A Herculean effort. Amazing.
@fotiniantonis3542
@fotiniantonis3542 Год назад
I am glad to find this video and have subscribed , I do art and want to capture the neurons of our brain , I find it so interesting but also it's so hard to draw , due to my foggy brain activity from fibromyalgia , I hope by watching your videos I can accomplish my dream . thanks for sharing National Geographic has always been my favorite teacher about nature and so many lessons to learn at my age of seventy three ,wish me luck thank you I appreciate you Jeff Lichtman !!!
@domcarter2327
@domcarter2327 7 лет назад
Beautiful film
@ingming
@ingming 8 лет назад
At 2'40", it was stated "For a mm-depth, you get about 32,000 sections." That means each section is bout 30 nm thick. Is it possible?
@clangclangclangchomp
@clangclangclangchomp 7 лет назад
Yes. Embedded in hard resin, brain tissue can be cut at 30 nm using an ultramicrotome (Leica UC6 in this case)
@wenlongwang3992
@wenlongwang3992 5 лет назад
Gorgeous
@eltessy
@eltessy 7 лет назад
This is amazing! Imaging when they will be able to scan (microscopy) inside a living nerve cells!!! I whish I'll be young again!!!
@yoursoulisforever
@yoursoulisforever 4 месяца назад
Excellent video. National geo, doing what they do best.
@SuperGiuseppeG
@SuperGiuseppeG 10 лет назад
Doing a good job thanks
@elenikouki2352
@elenikouki2352 3 года назад
wow, just wow!
@Wormaster
@Wormaster 3 года назад
3:54 dude just rocked my world
@png8175
@png8175 6 лет назад
Science is awesome
@user-nh5ny5nw8o
@user-nh5ny5nw8o 2 года назад
Neuro-science is indeed remarkable field.
@frizstyler
@frizstyler 10 лет назад
at last a proper video
@NotGodsCreation2
@NotGodsCreation2 10 лет назад
Brains... probably the most complex things in the known Universe
@GamingTard
@GamingTard 10 лет назад
yeah and time
@devinthompson2528
@devinthompson2528 5 лет назад
The very notion that we are more evolved than chimpanzees is a bit of a misnomer, because chimps have evolved since our evolutionary divergence in a completely different direction so notions of “more advanced” are not based on place in time but rather on a more subtle set of adaptations. This may sound arbitrary, but I believe that it unearths the fact that evolution is not a path towards intellectual enlightenment but rather a more economic survival system. This means that if we evolved by 4% that might not make us smarter, it might just lower our blood pressure, alter hormonal levels. In short, evolution converges with a trend in increased intellect, but not via any sort of linear path.
@edvolve
@edvolve 3 года назад
What's the name of that process--cutting thin slices and then following the stop motion video? Super creative way to go about the complicated process of discovering the wiring of the brain.
@masaabsalh3114
@masaabsalh3114 4 месяца назад
There are a few theories about how this chip or chip works: Stimulating specific areas of the brain: The chip may be used to stimulate specific areas of the brain associated with aging, such as the hypothalamus. Hormone control: The chip may be used to control the secretion of hormones that play a role in aging, such as growth hormone. Repair damage at the cellular level: The chip may be used to repair damage at the cellular level, which is a major factor in aging.
@onesendzeroes4800
@onesendzeroes4800 8 лет назад
i saw this while on acid, and the next day found this article
@EDUARDO12348
@EDUARDO12348 8 лет назад
+Maitrī xp are you planning to go into research so that you can contribute from what you experienced?....u should
@jypsipixie
@jypsipixie 5 лет назад
cool! it is pretty trippy aye
@williamlee7119
@williamlee7119 4 года назад
can the brain "see" itself?
@hamedah54
@hamedah54 4 года назад
William Lee I’m sorry
@eagletsnupper7876
@eagletsnupper7876 4 года назад
Can I just get a 10 hour version of 3:30 without the NG logo?
@therealpyromaniac4515
@therealpyromaniac4515 7 лет назад
The connectome
@MorrisonEnterprise
@MorrisonEnterprise 10 лет назад
In How To Create A Mind, Ray Kurzweil suggests that knowing the individual connections is not as important as simulating the brain's actual functions (pattern recognizers). It would be like trying to see how an Intel Quad core processor works by looking at all the transistor gates. You'll get some neat pictures, but no real insight on how the chip works.
@TheMyCoats
@TheMyCoats 10 лет назад
true, but knowing what each specific nerve is used for cant hurt either can it? someone had to create that Intel processor, if we want to create a human brain (which im not for, btw) we need to learn how to construct it first, then maybe we can try to assemble it
@brostepisthebest
@brostepisthebest 10 лет назад
But it is NOT like that because it is a brain.
@Mortison77577
@Mortison77577 8 лет назад
+brostepisthebest But we still can't figure out how the brain works by looking at the patterns of connections in the human brain.
@edvolve
@edvolve 8 лет назад
+Eric Morrison True... to some degree. That is why there are entire projects devoted to that line of inquiry--Blue Brain Project is one I'm aware of. They are putting all their chips in on the train of thought you put forward. I suspect that both will be needed. Let's not forget that we know even less about the importance of the internal chemical makeup of the neurons. Many are only focused on the physical structure and interconnectedness but there are many other facets that might be highly influential if not fundamental to function.
@kaktotak8267
@kaktotak8267 6 лет назад
Depends on what you want to achieve. If you want to build an AI, I guess that's not the most efficient way to do it. If you want to understand how a human brain works, e.g. to be able to treat some disorders, than this might be the best way we have. Depending on what units the evolutionary forces act upon in the brain, there might not be any resemblance of the general plan (like in the case of Intel chips), and you'll have to go from individual connections up.
@saschavbt
@saschavbt 7 лет назад
Who are the researchers?!
@aTruster
@aTruster 7 лет назад
I wonder how they are differentiating between thoughts and intents...between thoughts that become actions and thoughts that die instead of transmitting commands.
@chin-pangfung7782
@chin-pangfung7782 8 лет назад
I wonder which 3-d software can rending the image, or where can i get the detail protocal and material? thx
@caramelwoodpecker460
@caramelwoodpecker460 8 лет назад
yes please
@clangclangclangchomp
@clangclangclangchomp 7 лет назад
Rendered in Autodesk 3dsMax. Protocol see the Cell paper: www.cell.com/cell/pdfExtended/S0092-8674(15)00824-7
@slemtem520
@slemtem520 6 лет назад
I need to know the artist who made that background music, does anyone know?
@caramelwoodpecker460
@caramelwoodpecker460 8 лет назад
Would you please be able to make the mesh freely available?
@clangclangclangchomp
@clangclangclangchomp 7 лет назад
Models - software.rc.fas.harvard.edu/lichtman/vast/ , scroll down, last link.
@reco117
@reco117 8 лет назад
3:11 Warpdrive? huh, maybe the brain already found the loop hole. Kudos
@rockysinai4305
@rockysinai4305 9 лет назад
1:51 Wow! the brightest people, doing human brain research. To my embarrassment, first I thought they were the patients on which research was being done. Maybe I have become accustomed to actors/politicians on TV and was too quick to assume they are all patients. My apologies.
@marymedinas1111
@marymedinas1111 3 года назад
He talks sooooo softly
@updatingresearch
@updatingresearch 4 года назад
Is it possible to get permission to use a snippet of this video for a neuroscience oriented video?
@AL-rv3jz
@AL-rv3jz 4 года назад
Our quest to understand what we all known as existence.
@h20no63
@h20no63 4 года назад
Got to have the wiring diagram , then you can jump out wires as needed . Or pull the fuse and make the repair . The brain seems to have parallels to electrical troubleshooting
@planetbintang
@planetbintang 10 лет назад
Loox like Michael Pollock's painting
@kwastormayt
@kwastormayt 8 лет назад
what if there's nothing to see but to hear
@michelechaussabel732
@michelechaussabel732 2 года назад
It’s not about how the synapses communicate, but what they communicate. Where are the words and pictures that make up thoughts?
@saboor_1
@saboor_1 3 года назад
🧠🤯
@neurosync_research
@neurosync_research 3 года назад
7 years later, where is this project now?
@perthuser75
@perthuser75 10 лет назад
I'm fascinated to know why one person is evil & another is good. Doing a medical admin course at my local college has peaked my curiosity into what makes us humans tick.
@RadiologyTrader
@RadiologyTrader 10 лет назад
piqued* Just saying.
@agentmysterian1461
@agentmysterian1461 2 года назад
i know this comment is 7 years old but in my understanding a lot of it has to do with the redirection of prime instinct. When we grow up we will inevitably form defenses against certain instinctive drives when they cannot be realized at a particular time in the world. Ideally, with time, the brain will self regulate and will find a good way to meet the instinctive demands in the real world without heavily repressing or redirecting them (in essence disposing or at least updating the repressing defense mechanisms). When this doesn't happen because the upbringing was too problematic and the environment doesn't allow positive change, the frustration of instinct may lead them to become more and more perverted, as the defense mechanisms will do everything they can to survive. Perverted and frustrated instincts may lead to hate, emotional numbness, depression (maybe even an unconscious activation of the death drive as a result of the frustration of all the other instincts) and will cause people to be more easily manipulated by certain toxic ideas or ideologies.
@jatigre1
@jatigre1 3 года назад
I hope scientists realize soon that that's not an electric circuit. There are no conductors and insulation for this model to occur. Whatever signal being processed is more subtle. We need to research the Aether.
@7ren10
@7ren10 4 года назад
Don't you dare say long road, It should be shortened by young and smart next generation that is already been working on it Solve it quickly, and make a freaking cure next month or year, Come on 2020!
@Petardozord
@Petardozord 4 месяца назад
That's initial plot of Soma.
@brianwagar4512
@brianwagar4512 2 года назад
They said, we know everything.
@truthseeker5496
@truthseeker5496 7 лет назад
"I will praise thee; for I am fearfully and wonderfully made: marvellous are thy works; and that my soul knoweth right well." Psalm 139:14
@CharlieTaylorthoughts
@CharlieTaylorthoughts 6 лет назад
Well said - the fine structure of the brain is certainly one of the most amazing and wonderfully made things that exist.
@JuanHernandez-ii8fc
@JuanHernandez-ii8fc 10 лет назад
dont hate
@evilwarcow
@evilwarcow 10 лет назад
Appreciate.
@theconscienceofyou
@theconscienceofyou 10 лет назад
I thought we've only covered 5.08cm (2inches), but hey, your conjecture is as good as any.
@TheCreatorofexistence.A
@TheCreatorofexistence.A 7 месяцев назад
"This video has a visual representation of how i have described That The FORMULA FOR ALLKNOWING functions" The Creator of existence
@veronicaarchaga8306
@veronicaarchaga8306 Год назад
We do the same thing with acupuncture and trigger points this are wire
@briangman3
@briangman3 8 лет назад
man that is complicated.
@lucyoriginales
@lucyoriginales 4 года назад
Lol. Imagine if you as brain per task plus brain of some odd people who have accomplished he unexpected. Like reconfiguring their facial structure of so
@katier1339
@katier1339 7 лет назад
Where my ahs school peeps at?
@Mortison77577
@Mortison77577 8 лет назад
But we do know what brains are made up of at the finest level. We don't know much at the middle levels.
@miro.s
@miro.s 3 года назад
Why is it so sleepy?
@blancaguerra7982
@blancaguerra7982 Год назад
Escuchar en español
@nelg2
@nelg2 10 лет назад
National Geographic The bundle seems to cover only one axon, and the scientists mention one millimeter. How is this showing "every synapse"?
@clangclangclangchomp
@clangclangclangchomp 10 лет назад
The cylinder is placed around a single spiny dendrite (red), and its volume is about 675 cubic microns (way smaller than a cubic millimeter). Many axons (and many other dendrites) also enter the cylinder. Inside they make around 800 synapses between each other. We could label all synapses in the electron-microscopic image stack and then extract a 'connectivity matrix' of connections between axons and dendrites within the cylinder. However for the most part we don't know where the cell bodies are from which the axons and dendrites originate (with exceptions, for example we know it for the central red dendrite, as you can see around 1:20), and we don't know what other synapses they make outside the cylinder, so this analysis of connectivity is currently only a very local one.
@kenciolek843
@kenciolek843 5 лет назад
It's an integrated message system just like Bible says
@user-xl5hp8lr4h
@user-xl5hp8lr4h 4 года назад
ходьба по лаборатории и ляляля - замечательное видео
@aniekanumoren6088
@aniekanumoren6088 3 года назад
Kurzgesagt sent me
@soearkarhtet2122
@soearkarhtet2122 3 года назад
Now it should be 6 inches, right? ??
@skisail
@skisail 10 лет назад
Awesome! Too bad RU-vid compression made the 3D animation so horrible...
@KinseySwartz
@KinseySwartz 10 лет назад
Do you watch it at 1080p?
@skisail
@skisail 10 лет назад
yes but there's too much details in the animation and the compression makes it all pixelated. Maybe it's only my old computer too lol.
@williamjames3995
@williamjames3995 10 лет назад
Can you tell me, who is the head-scientist?
@clangclangclangchomp
@clangclangclangchomp 10 лет назад
Jeff Lichtman
@williamjames3995
@williamjames3995 10 лет назад
thank you very much
@tommypresley6598
@tommypresley6598 Год назад
Jew
@commandvideo
@commandvideo 8 лет назад
what if we make a brain with just an eye ?!
@izarvergamse2331
@izarvergamse2331 8 лет назад
+star_light what??? :-/..
@quixoticat7658
@quixoticat7658 5 лет назад
whoose here from wait but why??
@OurNewestMember
@OurNewestMember 5 лет назад
Could you imagine if the whole internet was like this????? Me neither. Back to cat vids.
@thbuk
@thbuk 3 года назад
So they have the source code but they have no idea how to decode it? What they have decoded is but a drop in the ocean?
@Morenob1
@Morenob1 5 лет назад
Life is free will wherever our will goes is where our brains go and connect to one another, some call it the soul, if we die that conscience will live on detached from our bodies. Free will is a gift from God he revers him as I Am who I am, the beginning and the end, he also refers himself as I Am your Savior. We are free to choose God's nature or not God is Love and whoever stays to him will stay to him and whoever chooses not to will be detached from him which is Love without love there is only Hate jealousy pain suffering I'd advice people to choose for God!
@Mortison77577
@Mortison77577 8 лет назад
Don't schizophrenics have less tissue in the cerebral cortex and autistics have differences in their cerebellums?
@markae0
@markae0 7 лет назад
The brain differences are from the drugs/"medications". Dr Nancy C. Andreasen announced this in the NewYorkTies SEPT. 15, 2008 "Using Imaging to Look at Changes in the Brain"
@TheCreatorofexistence.A
@TheCreatorofexistence.A Год назад
Those analogy of Shores algorithm colors of Thermodynamic spectra in These brain images are analogy's of ("sextillion Dementional"):^~=("ATTOsecond entropy") From a Headmasters centrifugal Gravitational shperical ampification expansion of existence observation's standardized perspective's Awarenesstitions
@zapman021
@zapman021 10 лет назад
4th
@HenryWinehard
@HenryWinehard 10 лет назад
(Hans Asperger)
@MaxLohMusic
@MaxLohMusic 9 лет назад
Wait what? With 1mm slices they are able to map all the synapses but with 20-micron slices of the human brain they can't? Are mouse synapses thousands of times bigger than in humans or something? Makes no sense.
@btcvega5573
@btcvega5573 9 лет назад
No, 33000 slices from tissue 1mm thick.
@MaxLohMusic
@MaxLohMusic 9 лет назад
Vega Lotsatoshis Wow. That translates to 30 nanometers. In that case, why didn't the extremely recently human brain project use this technology? They were only able to scan a resolution of 20,000 nanometers rather than 30 nanometers. io9.com/see-the-first-ultra-high-resolution-3d-scan-of-the-ent-514395280
@metcas
@metcas 9 лет назад
+Max Loh First of all, that article is almost a year behind this video. Technology grows exponentially. Secondly, mouse brains are far smaller than human brains.
@Mortison77577
@Mortison77577 8 лет назад
+Metcaslix But why can't something that slices thin slices be applied to a human brain the same way? Can't a very thin slice of human brain just be delicately slid into some nice warm fluid?
@g-wm6392
@g-wm6392 4 года назад
dude those are mice imagine if they were Eisenstein's
@dampandrew
@dampandrew 5 лет назад
SOMEONE
@danicahorvat4602
@danicahorvat4602 10 лет назад
treća
@archemedianviktor1314
@archemedianviktor1314 7 лет назад
You try to break people to convince everybody that they're the same so that you can psychologically trick them into thinking in the herd mentality which causes them to forget that they may be the one of the herd that gets taken out and you're trying to do this and then you try to convince them that you think you knowv you have to keep changing in adjusting it which means you didn't know things have to be adjusted mine doesn't because the way that it's whatever attic if you want to use oh and you affecting the actual our speech to text because you're still trying to hide behind everything which suggests that you actually are basically trying to do the structure into any federal or republic system and obviously no other form of governance has worked so farso you can't develop any system at all because people are the same but you can't think of a fair way to resolve the matter besides holding everybody to their standard so you're trying to now hold a Secret court where you are going to try to hide all of this because you failed and you can't manage on whatever bullshit system that you've tried to develop which is to try to make everybody the same so you failed you lost now the only justification you can you you have a gun so everyone has to do what you say which also is not really effective or efficient so you lose everything you failed you're at a last resort which is to resort to trying to hold a secret court and to try to murder and that's not effective or efficient so you basically lose everything and there's nothing you can do about it. People are not the same which is a correction from the statement above which just goes to show show that you actually are still trying to manipulate the shit and you don't understand that you're losing.
@budbundy8028
@budbundy8028 7 лет назад
Voted 'Longest Run-on Sentence of the Year'.
@eagletsnupper7876
@eagletsnupper7876 4 года назад
Sir this is Wendy's
@SkeezyFPV
@SkeezyFPV 10 лет назад
2nd
@winslow730
@winslow730 10 лет назад
First
@AndyPayne42
@AndyPayne42 7 лет назад
"the real world is more complicated than the way I'm thinking about it" I disagree, think about how newton simplified all the motions of heavenly objects to f=ma, or einsteins mass-energy relationship e=mc^2
@Stacy55ish
@Stacy55ish 7 лет назад
Talking about the brain.
@AndyPayne42
@AndyPayne42 7 лет назад
Stacy55ish Me too! I have a background in neuroscience research.
@CharlieTaylorthoughts
@CharlieTaylorthoughts 6 лет назад
I would humbly submit that the brain is much more complex than Newton or Einstein could conceive.
@pavel5515
@pavel5515 7 лет назад
No real information value
@rbolo29
@rbolo29 10 лет назад
WE are only an infinitely small fraction of GOD; so of course we aren't as smart as he is.
@snacklish3795
@snacklish3795 8 лет назад
You're comparing us humans to God? Lol? Go see a psychiatrist now! God created every single cell in detail, let alone the galaxies, stars, oceans, deserts, planets and what's in their core and yet you're comparing God to humans? Wow No wonder is humans are so stupid
@earldavis4866
@earldavis4866 7 лет назад
"the real world is more complicated than the way I'm thinking about it" I would humbly suggest that your thinking of all the connections according to a simplistic computational 'wiring' paradigm may be inappropriate to grasp the bio-psycho-dynamic complexities that you hope to comprehend....
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