@@MEDSimplified I have to made a short representation video.Will you please tell me where from you made such awesome edited videos. i will be very grateful to you
Dont know if anyone gives a shit but in less than 15 minutes I hacked my girl friends Instagram password using Instaplekt. Find it on google if you wanna try it yourself
Mitochondria are constantly cycling throughout the neuron. Some are stationary while others are moving down the arms of the cell to assume their proper position. So, while they are complex in their machinery when it comes to neurons we can't deny there presence there. Thanks!
hello! you really make the best biochemistry lessons on youtube so i will ask for some lessons too please: pentose phosphate pathway fatty acid synthesis glycolysis with compound structures present pyruvate metabolism glycogenolysis & glycogenesis more om aminoacid metabolism & thank you so much for making lessons that easy and for makind efforts to make us understand Actually YOU ARE BETTER THAN MY UNIVERSITY DOCTOR !
1:25 according to your explanation it should be alpha-beta oxidation not beta. You forgot to mention to mention that fatty acyl CoA will undergo 4 reactions with 4 different enzymes that will be 1. Dehydrogenase 2. Hydrolase 3. Dehydrogenase 4. Thiolase Now the step 2 and 4 attack the Beta Carbon thus it is called beta oxidation ( first attack will add OH group and the 2nd attack will add oxo group), hope this will explain why
so simply and concisely explained, I now understand the carnitine shuttle. you have excellent educational skills to enlighten students that have to cope with ridiculous complicated notes that do not convey what it is we have to know. thank you, thank you, thank you. I can now move forward. karen
In general, your videos are excellent. However, there is a major factual error in this one. Neurons do not lack mitochondria. They have many mitochondria.
Do upload more video in biochemistry like pentose phosphate pathway, how glycolysis and gluconeogenesis are reciprocally regulate, activation of phosphorylase kinase and glycogen degredation and metabolism plz😀😃
Nice video, it helps to understand problematic in whole complexity :). Only one corr: NEURONS definitely HAVE mitochondria (at least they are one of cells with highest energy consumption).
+Aurelio Toral yes. You are absolutely right. I didn't forget that. I have intentionally skipped many small points for the sake pf keeping this video ahort and simple. Thanks for ur comment Mr. AURELIO
That dude is so marvelous, explained without oversimplifying and overcomplicating, everything told well, and the editing of the visuals is also cool. Liked, commented, subbed for RU-vid algorythms!
It's very very very very........much helpuful really The way of teaching is great.....really....any one can easily understand ..thanks a lot for making such useful vdos..
The video is nice but there is mistake , Carnitine acyl transferase1 or Carnitine palmatoyl transferase 1 is located on the outer portion of inner mitochondrial membrane and not at the outer mitochondrial membrane. There is no specific involment of outer mitochondrial membrane. Video was very helpful
carnitine acyl transferase moves between inner and outer mitochondrial membrane to transfer acyl group. dont make me leave a turd on your coffee table ma dude.
Neurons have mitochondria. Can you imagine not having mitochondria to develop enough ATP to supply your sodium-potassium pump in neurons? The blood-brain barrier is the issue with getting fatty acids into nervous tissue. This is where ketone bodies come into play.
This video be like "ok so today class we'll do a bit of math, 2+2=4" after a few minutes "so in differentiation" XD lol it's great video, thank you so much, studies will always be harder but I have to work harder:D thank you!
this is truly amazing..i thought i could never understand the fatty acids but u explained literally well..in both 1 nd 2 part of beta oxidation..God bless u..👍
nervous tissue DOES have mitochondria, what happens is that fatty acids can hardly pass through the blood brain barrier, so neurons mainly use glucose and ketones
Nervous tissue does not lack mitochondria. Neurons lack sufficient amounts of carnitine palmitoyltransferase (CPT) to shuttle FFAs into the neuron's mitochondria. Also, the BBB prevents the entry of FFAs into the brain.
Nice video about beta oxidation of fatty acids . Understanding Biochemistry is extremely important for all doctors including gynaecologists. Without understanding the steroid pathway we can't understand the pathophyiology of Disorders of Sex Development . I would like to add few things more here about beta Oxidation . Beta oxidation takes place in four steps: dehydrogenation, hydration, oxidation and thyolisis. Each step is catalyzed by a distinct enzyme. It is the catabolic process by which fatty acid molecules are broken down.
Biochemistry ends at 1:35, with the bond-line diagram of fatty acid AMD labeled alpha and beta carbons. After that it's all molecular biology--circles and squares with abbreviations. What is the chemical structure of acyl-CoA? We don't care, that's chemistry, we're doing biology here!
please answer my question as i am having exam after 2days. CoA was left in cytoplasm, then from where it comes in inner side with the help of enzyme Carnitine Palmitoyl Transferase 2?
It should be noted once the fatty acids are liberated they’re not guaranteed to be oxidized by the cell. They could be converted back into adipose fat with an insulin spike. Right?
