Metabolism | Fatty Acid Oxidation: Part 1

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Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will present on part 1 of this two part series on fatty acid oxidation. During this lecture we discuss the transport of fatty acids within the bloodstream, as well as the activation of fatty acids. We also talk about the translocation of fatty acids from the cytoplasm into the mitochondria via CPT-1, and CPT-2. We hope you enjoy this lecture and be sure to support us below!
We also have a discussion on the 4 stages of beta oxidation:
1. Oxidation
2. Hydration
3. Oxidation
4. Thiolase activity
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#ninjanerd #FattyAcidOxidation #Metabolism

Опубликовано:

3 июл 2024

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Комментарии : 574

@Mani-hs8dd 5 лет назад

I attend a fu**ing 4 hour lecture about this exact same content and I don't understand a word , but I understand it all in less than 30 minutes vid with this guy, dude this is unfair

@juancorrea8591 4 года назад

Monyal Knowing that these videos are free, and that I’m gonna be paying tens of thousands of dollars in loans for inferior lectures makes me angry lol

@wallmethod 4 года назад

Thats bec you attended! Each lecture is a “build up” to the next level :)

@meghanac6128 4 года назад

Same here

@hhykk 4 года назад

same lol i Spent three days

@ayushthakar691 4 года назад

Might be you r dumb

@moonchildc3894 11 дней назад

I know I'm late but honestly saying you're a LIFESAVER !!!! I understood so beautifully 💜

@kevo1295 6 лет назад

Dude, you're a genius. Metabolism actually makes sense now. Thanks.

@NinjaNerdOfficial 6 лет назад

+kevo1295 That’s awesome! Glad to help!

@jamyangbhutia9936 6 лет назад

You are amazing man! I wish there would be professors like you in our college. Keep it up man. Waiting for new vids👍

@mahawafofanah631 5 лет назад

Thanks ninja

@muhammadazanafzalbutt1004 4 года назад

Yay man!!!!

@muhammadazanafzalbutt1004 4 года назад

You r awesome

@zeebalz7038 3 года назад

Greetings from Nigeria 🇳🇬 You’re appreciated ❤️

@RUYINAETENGsMEDICDIARY 2 года назад

Nice to meet u❤️

@clintonodinaka6737 2 года назад

🇳🇬 9ja

@nickygm3429 2 года назад

Thank a lot! saving me form med school. Btw I want to comment that in 20:21 the enzyme used is B-hydroxyacyl CoA dehydrogenase in order to move to B-ketoacyl CoA. Thanks a lot.

@chitrakarcosmo 23 дня назад

Yes

@questioneverymatter5851 День назад

@@chitrakarcosmoI was like why acyl CoA dehydrogenase responsible for convertion to Enoyl acy CoA. So B-hydroxyacyl CoA dehydrogenase responsible for the conversion to B-ketoacyl CoA. Looks like the reversed process of Fatty acid CoA synthesis.

@alfiemed1317 4 года назад

Well done, but there’s a small mistake at the beginning of the lecture. You mentioned that atp is converted to adp in fact it’s converted to amp and the 2 inorganic phosphates and the phosphoanhydride bond is broken by inorganic pyrophosphatase otherwise perfect video

@nancyezike7952 3 года назад

Awesome!! Thank you so much!!

@sciencenerd7639 3 года назад

thank you for adding this clarification

@teomatsa6836 2 года назад

dude speak English

@basharathussain7212 Год назад

What is atp and ADP bro?

@roqeebatbolarinwa670 Год назад

@@basharathussain7212 ATP is Adenosine tri-phosphate. ADP is Adenosine di-phosphate.

@nidaiqbal7216 3 года назад

I literally don't know why I get excited when I listen to you .... I just start walking with the excitement that I have got the core concept that I couldn't get when I listened 100 other videos. I think you are the most underrated man on utube , u deserve atleast 10M or more.... I can't appreciate you with Thankyou only .... U deserve award for all your efforts. I wish you never stop making videos please My Favrt processor in All of my life 🖤🖤🖤 Countless blessings ❤️

@tchdkstar3944 4 месяца назад

I know I am watching this 6 years later, but I just want to say you are a genius. I used to hate biochem, but by watching your videos, I am now omw to become a biochem guru. Thx

@naseelmoursy6970 2 года назад

Man you are a life saver for real!!! I would've never understood Biochemistry without your videos😭! THANK YOUUU😍

@Hugo-no1si 6 лет назад

In one word: LIFESAVER. Thank you so much!

@NinjaNerdOfficial 6 лет назад

You are so welcome Hugo!

@patiencejohnson4837 4 месяца назад

Literally ❤

@nizamulhaq6886 2 года назад

no word of appreciation can entirely explain your personality SIR U ARE SUCH A GENIUS PERSONALITY ALOT OF LOVE AND RESPECT FOR YOU.U ARE JUST AMAZING SIR.

@momo-mn7wn 3 года назад

You're a genius man!! I spent my whole day to understand this and i got it in 40mins..hats off to you

@ahmetziyaaktas9179 6 месяцев назад

I adore your knowledge of Biochemistry and enthusiasm. How clean and pleasant an explanation this is! 💕

@Dr_Harsh07 2 года назад

Reading my book after 30 mins of ur lecture is smooth ... Thanks a lot u are a life saviour

@sohaibalaa8228 4 года назад

Brother I’m really owe u, u summarized about 2 three-hours lectures in about 30 minutes! u r incredible!!

@amynainan1157 3 года назад

You are a legend thank you so much for helping me through med school... You manage to do more in half an hour than hours of professors or the textbook😁

@darshinimalukar3246 2 года назад

All the praise here multiplied by 100, and that still wouldn't suffice what an amazing lecture this is.

@learnwithareesha458 2 года назад

Ninja nerd is a blessing. This channel has helped me so much that a small thank you just won't do justice. I'm so grateful 💫💫

@parvathitiruviluamala9870 2 года назад

I never paid attention to this while in Medial School. What an AWESOME teacher !! God bless you !!

@AjaySensei 3 года назад

This is the absolute best video on fatty acid oxidation i've ever seen! I feel like I just had an epiphany.

@fayyoosh7870 3 года назад

I like how we all in comments are amazed and thankful for ur great explanation .. thx ! ❤️

@user-vw4yh6ld7n 5 лет назад

You’re saving my life with your videos

@bhavanakathuria3697 5 лет назад

You deserve more views. You easily explained something my "highly accredited" professor couldn't in 53min, while you did in less than 30. THANK YOU!!!

@elianjoensen2756 2 года назад

this is a scripted video. some would call that an advantage

@MarieKametani 2 года назад

@@elianjoensen2756 yea but he did it in one take pretty much

@elianjoensen2756 2 года назад

@@MarieKametani teachers do that too. it’s called real life, and they don’t have a script

@MarieKametani 2 года назад

@@elianjoensen2756 ohh my classes are recorded rn bc of covid lol

@jackjyoung 3 года назад

You explain things so well I watched it twice and probably will watch it again.

@afrozayaz7871 3 года назад

I can't even imagine looking at my book for metabolism buhh you're awesome. The legend ninja.

@zainab-dr9sy Год назад

My exam is in 2 weeks thankssssss you just saved meee and ur lecture notes are rlly so legit!! Keep uppp ur saving billions of medical students

@serena3135 3 года назад

Is it weird to say I love you? No? Okay. because This video just saved my life

@jokodubga6535 Год назад

Thank God, I finally understand the topic. Thank you Ninja Nerd, God bless you!

@sarahgutierrez5628 6 месяцев назад

This was the best teaching video I've ever seen, you're a great teacher ! Thank you so much!!

@vincentarthur8699 Год назад

Thank you very much Prof,you make Biochemistry more comprehensible,greetings from Ghana🇬🇭

@VG__ Месяц назад

Greetings from India. You're appreciated 🙏🏻

@Aleyofication 6 лет назад

Isn't it a Hydroxyacetyl CoA D.H and not the Ketoacyl CoA D.H in the third reaction?

@NinjaNerdOfficial 6 лет назад

+Op Nutrition You are absolutely correct! I am sorry for that mistake!!

@Aleyofication 6 лет назад

Np mate...great vids. btw!

@ZainabMostafa-gk5jc 6 лет назад

why did not u change it or added a comment till now ??

@baraaka5376 6 лет назад

Op Nutrition Why??? There is keton group😅

@nischayjairaj 5 лет назад

baraa ka because the dehydrogenase is acting on the b-hydroxyacyl-coa to form your b-ketoacyl-coa

@shanicem3929 5 лет назад

So excited when we finally got to the acetyl CoA. Yaaay. Finally

@igj3224 5 лет назад

Guys, amazing job! Just amazing!

@roshan6253 Год назад

Normally i wouldnt even like subscribe and pay for this knowledge but you my friend explain it soooooo easy im sold.

@ahmednaser7770 4 года назад

thank you for making everything we much easier and enjoyable.. you are putting a lot of effort ..I appreciate.

@marysia5525 Год назад

You are helping me get that exemption from biochem exam and I could not be more thankful!!!

@masoodahmed6276 3 дня назад

Brilliant. What a pleasant and rewarding experience for learning biochemistry with clarity.

@asserm.8047 5 лет назад

Great video!!!!! If only my professors were as good at teaching as u are 😂😂

@amirrezag 8 месяцев назад

You are a lifesaver for real!!!! Thank youuuu.

@Amanda-bk9lu 3 года назад

Better than my metabolism prof. I have a metabolism midterm tomorrow and you are SAVING me

@kusocm 5 лет назад

Nice and concise, I really appreciate what you're doing, particularly for people that cant afford education...but bear in mind, palmitoleic acid is a monounsaturated acid, necessitating more reactions that you drew, but for palmitic acid it is perfectly correct, and the thiol group is what connects the CoA to the acyl group.

@sophias4280 2 месяца назад

You're such a gem, thank you SO much for making all these videos

@osedunmeevans7051 Год назад

With your videos I don’t have to necessarily memorize but rather, to understand. Thank you so much!

@laceymauritz8053 4 года назад

you're like the guardian angel of grad school. thanks for teaching me science!

@markmuravec8624 Год назад

Amazing explanation! Thank you ninja master. I think you flipped the CoA-SH in the opposite direct. I believe it should be Acetyl-S-CoA, so that CoA is bound to acetyl with thioester bond:)

@chisomongalande8745 Год назад

can't figure the actual words to use to thank this guy😁.. he's absolutely the best of the best😍, thank you@ Ninja Nerd

@uroojmustafamalik9249 5 лет назад

superb...💕💕MAY ALLAH BLESS YOU SIR💛💛

@imeneamina2342 6 лет назад

can't find a better video sooo simple thaaank youu from north africa

@user-vu9st6fd7v 2 года назад

This is beyond description ... Thank you so much!!!

@zainabs4159 Год назад

this guy is a LIFESAVER

@gihanimanodara4264 2 года назад

Thank you for your determination and the excitement in explaining the processes so well! Love from Sydney Australia

@vinayakkapatral4246 3 года назад

Genius for sure... wonder how many hours of reading Zach has put in and his team getting this type of lecture.. Congratulations to Zach and his team!!! Best! Obama should see this and endorse it.

@anthonypeltier4039 2 года назад

What

@user-wi6ri4fz9k 3 года назад

You are just a real biochemistry savior, god bless you

@mhmde7260 2 года назад

You deserve major respect Thanks alot for your videos

@pavkata97 4 года назад

You are a very talented teacher. Love your videos!

@golgiskarimi927 4 года назад

It was amazing, thanks for the smooth and understandable explanation

@reyazeram 4 года назад

i cant stress how much your videos have helped me . thank u so much :)

@awetyeman5315 13 дней назад

Great job Nija nurd.I was struggling my head to get around this.Thank you as always

@MohsinAli-bu2os 2 года назад

I have no words to praise ur hardword , such an excelent work , mindblowing. U r a hero bro .

@kattran3798 3 года назад

This helps me sooo much with the MCAT, thank you!

@user-hc2yx9tp2n 2 года назад

you help us alot I'm so thankful to what you do 💙💙💙 عاششش يا كبير

@raghadalomari4058 6 лет назад

why would 4 people dislike this phenomenal video??? Thank you tons!

@tejasvidalla2982 6 лет назад

Nice video sir.. but a small correction .... in the first step.... ATP is converted to AMP + PPi... which is converted to Pi by an enzyme inorganic pyrophosphatase ... this makes the first step irreversible!!!

@GoodKnight5252 5 лет назад

first thing i was going to say! they should fix it....

@guffronagung8316 4 года назад

i think tejasvi is right

@GoodKnight5252 4 года назад

@@guffronagung8316 i saw it in lehninger but I'm not at home right now to confirm..

@umarjalal397 3 года назад

@nidaiqbal7216 3 года назад

In which step? Please mention the step

@hilalkhan1881 5 дней назад

Greetings from Pakistan 🇵🇰 You are great person and appreciated❤

@anngitau810 Год назад

Beautiful work!

@mdnajmulhosen7259 4 года назад

Best lecture with good explanation

@maryamnisar3874 2 года назад

You are life saver Zach 🙌

@ritikatripathi7095 4 года назад

Best explanation on RU-vid

@MaylinGinestra 5 лет назад

I am in love with your videos !!! Thanks so much

@wendysinclair-smith984 Год назад

OMG. My Dr diagnosed me with non-alcoholic fatty liver disease. She said my blood work shows I am healthy but I'm not losing weight. She said I need to mobilize my fat. She recommended fasting and I didn't understand it until now. Now I know how to mobilize my fat. I thought she just meant exercise but I see what I really have to do Thank you so much

@fifi774 3 года назад

You're saving my year !

@franckynjantou8124 3 года назад

I don't even need to watch your videos lesson before liking...I like it with blink eyes.......I love your Teaching Professor...you are just amazing. I wish to be like you someday...really you overmotivate me. Thanks a lot/ Be blessed

@user-cs9nm3nz6o 6 месяцев назад

Amazing video now i got the concept thanks ninja😊

@gayathrid753 Год назад

Iam doing my ug.... And u r the most helpful part of my life for physiology and biochemistry✨ thanks a ton✨

@niusha3323 3 года назад

Cant imagine getting my degree without this channel

@riamishra3422 3 года назад

So much satisfying lecture..... Thank you so much.....

@beautifyingnaturewithcreat2498 2 года назад

Just amazing man...urs lecture just cleared my all concept related to oxidation of fatty acid...m very thankful for it

@stavhen7753 2 года назад

You're amazing. I had no idea how simple this could be, thank you so much for your efforts!

@hayllatte 4 года назад

thank you so much. you helped me for my final ❤️

@maxdb550 2 года назад

All my classmates study with your videos :) They are amazing

@aniketbrar4759 4 года назад

God bless yall at ninja nerd. Ily. ❤️

@mirembechristine3942 2 года назад

thanks cause you have really simplified medical school for me

@dler5360 Год назад

man I don't have words to describe how much i'm thankful for you. You didn't just make biochem esaier, but science in all its branches. thank you very much professor Zach i love you. ❤❤🤍🤍

@sapphiregem12 3 года назад

This really help! Thank you for making this video

@sploallthyme 3 года назад

Thank you! This has helped me tremendously.

@hibazahid190 4 года назад

Thanks sir.You cleared all my concepts.A Clap of appreciation from PAKISTAN 👌👋👋👋

@vinayakkapatral4246 4 года назад

Zach... You are amazing I am hooked to your lectures,

@DaRa-lw6rw 3 года назад

Bravo man! I'm and grateful and full of inspiration to get more and more! thanks!

@vetsathi9154 5 лет назад

love you sir. your lectures are excellent and detailed.

@emtiazsproduction9455 Год назад

Great i understood beta oxidation fully with your video sir, while i couldn't understand anything from my BIOC professors.. Thanks a ton.

@SxCR4WR 2 месяца назад

I love this man, makes me love biochem

@parthajitdevpurkayastha2515 6 лет назад

It's Just too good....U Are really doing a great job ..Thanks a lot for your priceless efforts..

@vanshbhatia6190 Год назад

The way you present and explain ❤️😍

@ahmedallam1457 5 лет назад

Yeah.. Thanks alot.. Keep going u r the best for me ♥️🙆‍♂️

@KingSpark-bc1zd 14 часов назад

I really enjoyed your lessons and have recommended to all my friends

@co-extinction7626 6 месяцев назад

Thank you from Indian state ,BIHAR ✌👍

@Didsomebodysayslay 2 года назад

i attended the lecture at uni but didn't get a word and here i am completely understanding the whole thing thanks to u

@keenlass 3 месяца назад

I have a PhD in endocrinology and Diabetes and I still watch your videos (Have been watching since undergrad) and they still make my heart skip a beat 😍