Bill Rizer destroys everything with Drones in Vampire Survivors! 

iirc: White Hand is the official name, and Lore wise, it is the Hand of the Director. Meaning White Hand is the very game itself ending your run. It doesn't even deal or take damage, it just sets your max HP to zero.

QotD: i'd like it to be an original one, both of the first 2 DLC's were amazing. Of course, the 2 DLC collab ones were also amazing, but i want to see what they'll come up with next edit: the "death" that comes after you after beating the boss at the 27 minutes (or after killing a red death with either crinsom shroud or infinite corridor), has many names: "white death", "white reaper", and some people call it "white hand" for some reason. idk much about the lore, but my guess is that it exists so that anyone that is not on infinite mode, and is using one of the 2 evolutions mentioned, are forced into a game over. probably due to some game mechanic that elude me at this moment