My father-in-law was the first person to go through this trial. He has been completely cured of cancer. It's been 8 years since his first infusion and he's doing great.
I am in a clinical trial car t 22. I hope n pray I hear REMISSION. I go the beginning of March to have my cells put back in ❤❤ so happy for your father.
Tears just flow as I watch this amazing miracle. In January, I completed my chemo treatment. I am now a Cancer Survivor but am very aware of recurrences. So reassuring that if and when I do have a recurrence, there are outstanding treatments out there.
The common mistakes people make when talking about cancer is that they think is one disease. There is over a 100 different cancer, each one are very specific and are not equally treatable. So no we're not almost beating "it", we are on good way to beating "some of them" (which is equally great i reckon)
@@lukebatson5946 so we are screwed then now days is what your saying? Might as well say no to chemo and radiation cause that’s a living hell that will probably kill you slowly or transform your life to where you wish you were dead. You think it’s funny?
I've been battling Pancreatic Cancer, since 2020-October. The traditional FDA approved Chemotherapies of which I had 3 separate Tiers of them. FOLFIRINOX, then Gemcitabine/Abraxane then finally Capecitabine with Radiation. I am so grateful to my Oncologist, Surgical Oncologist, Radiation Oncologist and Thoracic Surgeon. They kept me alive this far. I will be entering a CAR T Clinical Trial in 2 weeks,as my Pancreatic Cancer has Metastasized. I pray this buys me more time on this side of heaven. I have a 1 and a half year old grandson, and I wish him to know who I am and not who I was. God willing, I'll take him fishing. 🎣
Every single person that has a deadly illness should not have to pay a dime to be treated. A sick child in a poor family should get the same care as a rich family! That poor child did not ask to be poor it makes me so sad to think about that.
@@NicholasWongCQ Free health is utopian for you? You can search about UK, Brazil and Portugal health sisteam. Moreover, in my opinion, free health sisteam is a matter of humanity
Doesn't happen in the real world. Period. Even when there is universal healthcare, there is budget, staff and facilities constraints. You may need to wait 18 mths for a surgery etc.
My Sister wS blessed enough to receive this. She has been on her deathbed for 8 weeks in the hospital . I blv she got every side effect possible .. Im Praying hard they figure this out b4 she passes. If she did get her blood cancer bk, it would be the quickest ever in this history's. Blessings and Peace To You All
Hi Kenneth, Thanks for your question. You can find current clinical trials offered through Dana-Farber here: www.dana-farber.org/Research/Clinical-Trials.aspx You can also search for clinical trials on this website: clinicaltrials.gov/ However, the website isn't constantly updated, and data is constantly changing. Hope that helps! -DFCI
Kenneth Carr you could try contacting cancercommons.org it’s free & via their website they take medical info & tell you what trials may be available & where. Good luck to your dad!
Also, not all cancer can be treated using modified T cells. Currently, the FDA has only approved treating leukemia using CAR-T cells against the CD19 receptor on the B cells. Organ Cancer such as lung, brain, etc .. are still in the early stages because T cells do not stay (or even multiply) in the organ long enough to kill all the cancer cells. You have to specially make modified T cells for each type of cancer because difference cancer expresses different proteins. For example, you cannot treat prostatic cancer with CAR-19 T cells.
Does anyone know, how does the car T cells specifically target only cancer cells? How do they avoid killing normal tissue? For example with breast cancer, how does it target cancerous cells while leaving normal breast tissue alone?
hi there! you asked this Q a year ago, so sorry for the late reply. I am researching cancer immunotherapy for my PhD. The T-cells are genetically engineered to produce a receptor that recognizes a specific antigen produced on the surface of ONLY your cancer cells. So this technique is highly personalized - therefore expensive. The receptor can be antigen specific chemically and/or based on molecular structure of the antigen target. hope this helps.
My father suffered from acute myeloid leukaemia and passed away on 2nd September 2019 after chemotherapy.... could this process would be able to save him at that time ..
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The corresponding tumor cells are also sequenced to get information about antigens on their surface. Accordingly only those constructs specific to produce tumor specific antigen are put induce the T cells to generate effective receptors. I hope it makes sense.
I'm currently an operator for this process, and I do this daily. The process I'm working on takes 7 to 10 days from fresh apheresis to frozen CAR-T cells.
@@roxydelafuente3512 Hello Roxy! I studied Biotechnology in The Netherlands. I'm Dutch myself. But actually any kind of laboratory/biology education will do :). Hope this helps.
Maybe it will be more effective if people know their family cancer history and correct the possible development of active cancer. And early treatment at age of 35 to 40y/o.
This treatment works well for B-ALL and CLL, Basically B-Cell blood malignancies, research is under progress for solid tumors. what cancer your parent is suffering from ? I am a CART Scientist at University of Pennsylvania the institution where CART originally developed.
@@silverstone9952 which cancer you are refering to ? This therapy works well for B cell malignancies such as B cell acute lymphoblastic leukemia (B-ALL)
