Despite the ongoing research from around the world to better characterize the effects and pathogenesis of COVID-19, the ways in which it interacts with or exacerbates cardiovascular disease (CVD) are not fully understood. While it is well accepted that SARS-CoV-2 infects lung epithelial cells, whether it can also infect endothelial cells is less clear.
In this webinar, Dr. Xuebin Qin will discuss his lab's development and characterization of new rodent models of COVID-19, and how his lab uses these models to study endothelial dysfunction and injury resulting from immune activation. Dr. Xuebin Qin will also discuss why HIV infection is associated with increased risk of CVD. He will provide an overview of the cellular and molecular mechanisms underlying HIV-1-associated CVD, and the mouse and NHP models he has worked with to elucidate them.
Key discussion topics will include:
- Cellular mechanisms by which SARS-CoV-2 and HIV contribute to cardiovascular disease
- Development, characterization and analysis of Mouse and NHP models for the study of COVID-19- or HIV-associated CVD
- Potential targets for therapeutic vaccine testing and pathogenesis studies
29 сен 2024
