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Cartilage Regeneration | Frank's Story

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Frank had a a torn ACL and a meniscus tear in his knee. The first doctor he saw told him he needed a knee replacement, and would eventually need to stop his very active lifestyle. Frank wasn't ready for that. Instead, he came to Penn Sports Medicine for a second opinion. He met James Carey, MD, who told him about a procedure called autologous chondrocyte implantation (ACI).
In ACI, a tiny piece of cartilage was taken from Frank's knee and sent to a lab in which it grew millions of cells. Once it was ready, Dr. Carey repaired Frank's ACL tear, and re-implanted his knee cartilage. Today, Frank is back to his healthy lifestyle working out at his CrossFit gym and running.
Get our guide to lower-body injuries, pain and treatment: goo.gl/8xb9Mr
Meet James Carey, MD, Director of the Penn Center for Cartilage Repair: goo.gl/v0XUTK
Watch more videos from Penn Orthopaedics: goo.gl/PK00MQ
Schedule an appointment with a Penn sports medicine specialist: goo.gl/8xb9Mr

Опубликовано:

26 авг 2024

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Комментарии : 132

@Sam-fp8zm 3 года назад

make beef/ lamb bone broth in the slow cooker. all the cartilage/tendons/ligaments etc dissolves off the sides of the bones into the liquid then have a couple of cups a day. store in fridge and reheat on hotplate. cartilage does heal itself.

@Ms-zg2nn 3 года назад

I've heard of this but didn't bother to make some. So just buy bones or whole part and save the bones to make broth? Need to add anything else beside water?

@Sam-fp8zm 3 года назад

@@Ms-zg2nn i buy marrow bones, scoop the marrow out, eat some raw, freeze the rest, and then either eat some raw each day or short fry time on the pan. with the left over bones i make broth from them which extracts any left over bone marrow (which tastes great) and also all the stuff on the side like commented above. i only use water. can add a little salt if desired. besides marrow bones there are just soup / broth bones or beef bones butchers sell which is usually neck or ribs and has cartilage etc on the side too. only downside of those types vs marrow bones is the marrow bones broth tastes better because it has some marrow left in it. the end part of the marrow bones has lots of the joint tissue stuck on it so that is great for the broth. there is a facebook group on bone broth (bone broth sippers) and PKD - The Paleolithic Ketogenic Diet is another good group.

@Ms-zg2nn 3 года назад

@@Sam-fp8zm The first thing I'm gonna do is go to Facebook and find the group that you mentioned, lol. You sure know some stuff about certain type of bones and difference between them. Thank you so much. I can't keep taking pain pills and refuse to get knee replacements. I just hope it works because it seems to be the only option.

@Sam-fp8zm 3 года назад

@@Ms-zg2nn yes and the pkd group also. bone broth alone is not enough to reverse major disease the pk diet is needed. thats what i eat.

@Ms-zg2nn 3 года назад

@@Sam-fp8zm So you're saying broth alone isn't gonna work? Must change the whole eating habit..

@wishbone103 3 года назад

Today is June 2021. Is this procedure more effective now or more advanced?

@atulpatel2850 4 года назад

I wish there were before and after Xrays. And video of actual procedure. Without that this looks like just another Ad.

@kobiecamp1134 Год назад

Yeah, it did seem like they only wanted to reveal, but so much.

@hafriz8746 4 года назад

Whats the cost

@martinbudde3186 4 года назад

I had an excision of a bipartite patella fragment four years ago at 20 years old because of chronic pain associated with the loosening of the fragment. This is a pretty rare knee problem and the three or four recommendations I got from doctors was to operate on it. This is after trying years of physical therapy, neuromuscular therapy, acupuncture, and myofacial release from differing places and people. In my case it wasn't a huge piece and the surgical consensus seemed to be that removing it would provide the best long term outcome. Unfortunately it only made my knee pain worse and limited my functioning even more. I believe that this may be because the fragment extended slightly into the articular cartilage of the knee. I have close to 100% functionality in the knee but when I try to exercise it in any capacity it causes intense lasting pain. I'm not a doctor but my though would be that in order to restore long term functionality and stability and functionality I would be 1. possibly repair any damaged cartilage and 2. find a way to have the knee function without out further damage to the cartilage on the anterior femoral condyle (where the exacerbation is located). Anybody have any thought on this?

@AdityaGupta-xq3kr Год назад

How are your knees now ?

@nbc950 3 года назад

Your themes are of great interest... so, it will be appreciated to lower the background (background?) music to be able to listen to the matter of interest. Thank you.

@chelleweatherspoon2226 3 года назад

I woud love to be able to run again and do the activities I used to do before injuring my maniscus and acl. Wow! Hopefully one day I could afford to do this. I used to be in such great shape. But not now.

@srikanthnalla7193 3 года назад

How much does whole prodeucre costs??

@srikanthnalla7193 3 года назад

It can be done subchrodal defect of articular cartilage??

@twerkinalisha7346 2 года назад

I have bilateral minescus tears. I'm supposed to have surgery. Can you do this after surgery or does it have to happen before it

@user-ks5iq1lf7f 9 месяцев назад

Crazy sad that these kinds of treatments are not available in my country😢 both my shoulders and both my elbows I have severe cartilage damage😬😬

@Ps4gaming-813 6 месяцев назад

Do prolonged Fasting it releases stem cells into the blood stream and they hunt around for damaged cartilage bone ect and they repair them they did a study on mice and humans

@lulucy3 4 года назад

Is it possible to give Frank my information? Id like to talk to him more about his recovery process, I am looking into this procedure for myself.

@bertlindsay 2 года назад

Anyone I Australia doing this sort of treatment please?

@lusajomwakisu8764 Год назад

How much does it cost?

@Englishease27 3 года назад

How to regenerate cartilage of knee please my mom is suffering

@vince1229 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-wP1Vv5Bzw_.html How to regenerate knees and meniscus - Dr. John Bergman.

@lusajomwakisu8764 Год назад

How can I get this service?

@MarkR2367 2 года назад

Where do I go

@TheReblman 5 лет назад

This would solve my father's problem since 1991

@Pfsif 5 лет назад

For the meager fee of 100 million dollars. Merica!

@Tacoman1967 3 года назад

The new oil industry is the medical industry.

@mahmoud3109 2 года назад

in march 2015 i had an acl torn, pcl partially torn and miniscus tear, due to life difficult circumstances and low quality, money motivated and careless sergons where am at right now i havent managed to have it repaired. now i have developed osteoarthrisis. life isnt the same anymore since i am full time strength and conditioning coach and lead an active lifestyle. trust me i have chronic pain and unstable knee. i would love some orthopedist surgeon to help me save my career. i am only 42 and i am good at coaching and i dont know how else to make a living beside my coaching career. pleaseeeeee some one help me.

@Kidthunder135 2 года назад

Look into R3 stem cell. They have clinics in the United States and they use umbilical cord stem cell which is a lot better than adult stem cell

@TheEmmlegend1 7 лет назад

Hello doc. I was diagnosed with moderate patellar tendonitis and chronic full-thickness chondral loss of the medial patellar facet in my left knee. I'm a basketball player and the doctor said that it could be a career ending injury since cartilage do not heal. I didn't have the chance to ask the doctor all the questions I wanted to ask because he was in a hurry to leave. Since MRI isn't always accurate, I want to have a second opinion in terms of getting another MRI to ensure that I really i have a full-thickness chondral loss before I call it a career ending for. I'm hoping that I only have moderate patella tendonitis and the full-thickness chondral is wrong. What do you recommend? Or do you have any advice for me? Thanks

@pennmedicine 7 лет назад

Hi Anthoney, Thank you for commenting. We are sorry to hear of your injury. Unfortunately, this account is run by our marketing division and we are unable to make medical recommendations or diagnosis. However, if you visit spr.ly/60588I410 you can learn more about knee treatments at Penn Medicine and/or request an appointment.

@JohnM... 6 лет назад

Anthoney monemou why not look into something called Undenatured collagen type two? It has been known to rebuild cartilage, as when you consume it, the antibodies in your system, which have been attacking the cartilage ( which consists mainly of collagen ) , sense there is cartilage in your stomach, travel there to destroy it, and thus allow the cartilage in the knee or wherever a chance to recover. Might be smthg to think about. Something else which may help is Great Lakes Gelatin ( essentially collagen type 2) the green packet, available on Amazon. I have had a tear in all 3 parts of my right hamstring for two years, and have been taking both, have gone down from 12 or so painkillers a day to just one, in the last few weeks of taking it. One more thing - home made chicken broth / soup. No, seriously. It is RAMMED FULL of collagen. Collagen is the building block of everything in your body. Whatever you choose to do, good luck with it.

@brianwilhelm9464 5 лет назад

Anthony, I had an ACI procedure done in December for my patella chondral defect. The procedure I had done is called MACI. Did you catch at the end of the video how long it took him to get back to Crossfit? My ACL tear took me a little more than a year to feel comfortable, but couldn’t catch what he said for his ACI comfort

@marianicola007 4 года назад

@@JohnM... Home made chicken soup with the fatty skin left on?

@brianwilhelm9464 2 года назад

@Roman Kover the MACI implant was successful, unfortunately for me I ripped up a different section a year or 2 later that I had removed, but my surgeon said the original MACI spot looked perfect. In the rehab process and getting back into physical action after MACI, i noticed a small hitch feel when trying to do uphill climbs on the bike or run up the stairs, I felt things weren’t completely smooth and I ignored that and I think when I was really trying to uphill climb on the bike I ripped some cartilage off on the non MACI section which i later had removed. Feel good now and getting by even though i have a new pothole. Just something to look out for. You need to rehab it the proper way, adhere to the non weight bearing periods, which i did, but i might of had some cartilage spill over in the setting period and create some issues for other parts of that knee

@davidlo168888 5 месяцев назад

8 years past already. Any further progress or just big pie in the sky? No cancerous cells produced?

@liviuterranova 4 года назад

It can be done also for a torn tendon who get shorter and cannot be reattached ?

@marktilsley8191 Год назад

Cost

@omegalgo297 5 лет назад

Thank you!!!

@omstygomsty 6 лет назад

Is the regenerated tissue fibrocartilage or true hyaline cartilage?

@backintobalance9542 6 лет назад

james hartnett fibrocartilage if micro fracture technique. Or real articular cartilage if grown in a lab

@babyghany9991 5 лет назад

Is this true? Dmso help with pain and repair some damage tissue

@SMRoss001 4 года назад

DMSO has helped me with relief from the pain of musculoskeletal injuries over the years. I highly recommend it. Also a natural solvent, apply it to clean, dry skin only.

@Ukrainian2 Год назад

7 weeks is not long!

@neuromancerXL 8 лет назад

This might be an option only available to wealthy people

@neptronix 6 лет назад

Cartilage regeneration that actually holds long term is very new. Very new = very expensive.

@invincible.5499 5 лет назад

@@neptronix how much does it nearly cost?

@neptronix 5 лет назад

@@invincible.5499 I have no idea. Invossa used to cost $10k a shot before the government pulled the license. Pentasan Polysulfate will probably be a hundred bucks a shot or less. Not sure about TPX-100 or sprifermin. Whatever these medications cost once they're approved will be less than a replacement knee though.

@saikatpaul6576 4 года назад

I heard it's cheaper than replacement

@babeena_gt_3645 4 года назад

@@saikatpaul6576 you heard wrong

@Maricelac21Realtor 4 года назад

I wonder if this works for arthritis in the hip?

@joef7011 3 года назад

Avoid ADDED sugars, plenty of carbohydrates & inflammatory food first. Try intermittent fasting.

@guiletexasranger526 5 лет назад

Car accident in January, still in therapies and concussion protical. Out in Michigan a hip specialist had me get an arthrogram and told me I should try cortisone but most likely a replacement is the only option.. I wonder if he's seen this video. Any recommendations for someone out here?

@newyorkguy158 3 года назад

there is an alternative to hip replacement that few people know about. It's called hip resurfacing. Surgeon shaves away the cartilage debris in the hip, puts a metal cap on it and a metal part in the joint to receive the bone with the metal cap. Cemented together. Bond is so strong, you could jump out of a plane with it. Like a new hip, but without removing your hip. You still have you hip and it's amazingly strong. I had it done in 2018, when I could hardly walk from OA. In 11 months, I was playing basketball again and I'm not even young! No problems with the hip at all. The hip is strong immediately after surgery, though it's recommended to use crutches for 1 week, then 1 crutch for 2 weeks. Immediately after being released from the hospital I walked to the supermarket and back, 1/4th mile or a little more. Surgeon who did operation is best in the world at this procedure, Dr. Su at the Hospital for Special Surgery in NYC. I wouldn't trust anyone else to do it. I paid for it, but you might have insurance that would pay for it.

@Ddstairclimber 6 лет назад

what is the difference between this and a stem cell culture procedure?

@atadali6199 6 лет назад

Ddstairclimber I think it is stem cell method they'r talkin about here

@BenatarTribute 4 года назад

Cartilage doesn't have stem cells or a blood supply therefore doesn't regenerate on it's own, according to another video I watched on the subject. This sounds more promising.

@carlacaires4679 3 года назад

@@BenatarTribute, and from what I've read, stem cells are cells which when transfered to another part of the body are able to differentiate into cells of that other part of the body. So, yes, it's possible to regenerate cartilage through stem cell therapy. (But it is said to be a very expensive procedure, which probably most people can't afford.)

@gratefulpianist8640 3 года назад

Frankly my name is also frank and i'm also trying to protect my knees

@kobiecamp1134 Год назад

Frankly a guy named Frank watched a video of a guy named Frank who had knee problems. And that's a lot of Franks.

@swathireddy4360 6 лет назад

Hi Iam 37 yrs from India suffering from condromalacia patelar in both my knees grade 2 and grade 3.Please let me know the treatment details

@tarun3154 5 лет назад

Hi swathi how r u now?

@platoniczna 4 года назад

I am in the same position as you. Grade 2 they told me but I'm sure it's getting worse. I cannot carry anything heavier than 2 kilos, otherwise, my knees are sored and inflamed. The above treatment here in Poland costs up to 12.000 zlotych, depending on region and clinic. I have always had problems with my knees, left one was dislocated 12 times, I was on my legs working physically for nearly 18years, now I am 42years old and cannot carry my shopping home, let alone running, walking, etc. It stops me from doing my daily activities. I have lost 4 kg of weight to help myself, but the problem doesn't seem to want to go away :( It's hard when you are a mum and have to carry on for your children and struggle to find the money for this treatment.

@kobiecamp1134 Год назад

@@platoniczna Put together a donation campaign in order to get the money.

@jim1732 8 лет назад

do you have anybody you can recommend im in Australia, Melbourne

@pennmedicine 7 лет назад

Thank you for your interest in Penn Medicine. Please refer to our Global Medicine program for more information about our services: www1.pennmedicine.org/global-medicine/

@Tacoman1967 3 года назад

He said the doctor was Frank with him and his name is Frank.

@lulucy3 4 года назад

How long did he say it took him to start back into crossfit after the surgery?

@jinshark9078 4 года назад

8 weeks. doctor say 6 months to participate impact activity.

@lulucy3 4 года назад

jin shark I keep trying to listen but I can’t understand it. I think he says after the first of the year which doesn’t give an actual timeline. He says it took him 8 weeks to be able to get up and ambulate. But not cross for until ..... (unknown) Thank you for the response.

@BT-km7nl 4 года назад

2.22 is a lie. those cells are long dead.

@josephtorres3229 4 года назад

I thought replication of stem cells was illegal in the United States

@chetan0409gmail 8 лет назад

I loss my shoulder cartilage can we regenerate it?? I am from India

@pennmedicine 7 лет назад

Thank you for your interest in Penn Medicine. Please refer to our Global Medicine program for more information about our services: www1.pennmedicine.org/global-medicine/

@JDKvideos 7 лет назад

I had micro fracture surgery of the shoulder and it helped alot.... so far

@gkrishna7291 6 лет назад

Pls check with Columbia Asia hospital Pune.

@kaushikkr4602 5 лет назад

Visit orthoone orthopedic hospital ,coimbatore bro and meet dr.david v rajan he is aged and has more than 45 years experience...i had knee cartilage degeneration after surgery iam fine now

@tarun3154 5 лет назад

@@kaushikkr4602 hi please tell more

@joemanly9519 3 года назад

If your not rich you don't need to watch

@babeena_gt_3645 4 года назад

I want this done but doctors say my insurance doesn't cover it

@kobiecamp1134 Год назад

You better put together some type of donation campaign to get the money.

@babeena_gt_3645 Год назад

@@kobiecamp1134 nah,I don't want donations. I am saving up my own money. So many people these days are in financial struggles enough. I don't want to take a meal from someone's plate to benefit myself. Thanks for the suggestion though 😊

@kobiecamp1134 Год назад

@@babeena_gt_3645 But in the meantime I've been told to take collagen peptides. Because that is good for the joints. So you might want to try it.

@BT-km7nl 4 года назад

unfortunately the cartilage taken for lab purposes is not holding the same structure in time. so what he has back is not what he had given, therefore degeneration will advance for him again, probably slower but it will degenerate.

@BT-km7nl 2 года назад

@Patricia not better than nothing. It is invasive to open up a hand

@lampmanjosh 4 года назад

Collagen Peptides can help repair cartilage. Take 3 servings a day for 30 days, and the once a day thereafter.

@Zero_thehero 4 года назад

lampmanjosh What are those?

@lampmanjosh 4 года назад

@@Zero_thehero it's just a dietary supplement that can come from different animals. The one I take is bovine(cow bone). Basically in powder form, and I mix it in OJ. Do your research, but I'll take this stuff the rest of my life.

@lampmanjosh 4 года назад

@Paul Katembo yes. It has eliminated my arthritis in my hands, and knees. Try it for 30 days. Do your research on the brand you try.

@Zero_thehero 4 года назад

Paul Katembo Yes thank you very much

@lampmanjosh 4 года назад

@Paul Katembo I take Vital Proteins. But, Ancient Nutrition is another good one.

@UHFStation1 3 года назад

It is always disappointing for the body to breakdown significantly before midlife. I would gladly die at 50 if my body was 20. Quality over quantity any day.

@kobiecamp1134 Год назад

I hear you as far as who wants to live a long life if you're unhealthy while living it. But at the same time dying at the age of 50 is way too young.

@mmabagain 2 года назад

I would imagine that only the wealthy can afford this.

@kobiecamp1134 Год назад

I hope not.

@maheshtanay 2 года назад

Glycine is main key to cartilage.

@kobiecamp1134 Год назад

Something to think about.

@maryirvine7182 3 года назад

Costs an arm and a leg .Not for a pensioner like me .

@geigercourtier 4 года назад

Reasonable,given his age...that’s another problem,aging.

@Automat1kkk 4 года назад

Grüß Gott.. schöne Erklärung! Thanks!! :) Hast du schon mal zufällig dieses spezielle Miracle Hydrogen Rich Water aus einem Wasserstoffanreicherer jemals kennenlernen können? Dieses Getränk ist richtig super! ☺ Es hilft einem echt gesund zu bleiben .. :D