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Celiac Disease Pathogenesis (Described Concisely and in Detail) 

PhysioPathoPharmaco
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Describes the intimate details of the pathogenesis of celiac disease.

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30 сен 2024

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Комментарии : 73   
@BenDabber
@BenDabber 5 лет назад
Playback speed at 1.5 is about right.
@ryanmichaelhaley
@ryanmichaelhaley 4 года назад
I like 1.25
@evanmilby6995
@evanmilby6995 5 месяцев назад
Probably the best animatic about Celiac disease
@aliceeleonor2911
@aliceeleonor2911 2 года назад
Awesome video! The pathophysiology is explained on point. Thanks!
@simonmandel2621
@simonmandel2621 2 года назад
Thank you for this video! I work in an Immunology Lab and am giving a presentation about coeliac disease to my team. This has given me a lot of help articulating it, so thank you 😊
@bio366geethasankar7
@bio366geethasankar7 Месяц назад
🙏❤️
@Cr7goat.85
@Cr7goat.85 3 месяца назад
Could you speak a little bit slower next time?
@DamjanManevski
@DamjanManevski 2 года назад
I'm a Nutrition and Biomedicine Master and wow, what an explanation! Really good job mate
@howtomedicate
@howtomedicate 5 лет назад
Seriously, amazing videos. I am a 6th year Medical Student and this videos still help me! You even inspired me to make a channel on my own! I make YT videos on medical topics. And today I posted a video about celiac disease as well. Thanks for all the knowledge bombs, and thanks for the inspiration. Keep it up, So will I!
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
Awesome 😎. Best of luck to you
@joc4709
@joc4709 2 года назад
Amazing. I'm a student dietitian and this was presented more clearly than a recent lecture.
@meryamlazrak1329
@meryamlazrak1329 Год назад
thnk you sir
@angusmack.2202
@angusmack.2202 2 года назад
Thank You too much 4 this! You really saved my project!! Very Clear Explanation :D
@dr.noir27
@dr.noir27 2 года назад
i appreciate the time you spent on making these animations
@AngryAmygdala
@AngryAmygdala 6 лет назад
You guys are the best, up there with Osmosis. Please, keep up the great work. I am fully supporting you.
@physiopathopharmaco4190
@physiopathopharmaco4190 6 лет назад
Thats so kind of you - thanks for all your support and all the best!
@Edward-ko9pn
@Edward-ko9pn 6 лет назад
It's amazing what us humans know about how the body works
@physiopathopharmaco4190
@physiopathopharmaco4190 6 лет назад
It truly is amazing
@brightdz2403
@brightdz2403 4 года назад
Nope we know less than 1 percent and every now and then we know more new things about that 1 percent.
@petersosa268
@petersosa268 3 года назад
@@brightdz2403 That “1%” is a whole lot though lol
@brightdz2403
@brightdz2403 3 года назад
@@petersosa268 I said less than 1 😂😂😂😂
@Enthalpy--
@Enthalpy-- 3 года назад
Laugh at neuroscience and genomics
@beautybeautyqueen6522
@beautybeautyqueen6522 4 года назад
Thank you for such an amazing explanation♥️♥️
@khankaseparhnahagee9530
@khankaseparhnahagee9530 4 года назад
Celiac is also spreading v quickly in the world like corona
@MoustacheAlexander
@MoustacheAlexander 2 года назад
Celiacs need to use hookworms. They put my celiac into full remission.
@sheilamacpherson4948
@sheilamacpherson4948 3 года назад
Way above me.
@thatsverycool8264
@thatsverycool8264 4 года назад
Just a quick question about AntiTTG, where do these come from? Are they due to mutations in B cell genes? Do people without celiac also have them?
@asmaarady2829
@asmaarady2829 4 года назад
thank you ,it was awesome
@petertriantafillou8058
@petertriantafillou8058 2 года назад
Great explanations Thanks so much!
@alysa4968
@alysa4968 6 лет назад
how was all of this going on inside me for 19 years and I didn't even know it
@alysa4968
@alysa4968 6 лет назад
also... really great video.
@physiopathopharmaco4190
@physiopathopharmaco4190 6 лет назад
Thanks for the comment, hope you're feeling better after going gluten free
@shamshahussein883
@shamshahussein883 6 лет назад
Alysa gluten free reverse able
@xleo4096
@xleo4096 Год назад
Helps a lot!
@UmeshKumar-xu2ng
@UmeshKumar-xu2ng 2 года назад
Sir i have celiac disease and suffering from lack of sleep is this normal?pls reply🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🙏🏻
@giorgiobozzoni8681
@giorgiobozzoni8681 6 лет назад
thank you very much for your videos from Italy. i have a question for you and i hope you have time to answer me becuase this doubt stopped me to keep going studying. what happen to those who dont suffer coeliac disease, once the gliadin is inside the lamina propria of the gut? how do they break down gliadin to get its amminoacids? i mean gliadin goes intact into the lamina propria also for those who dont suffer coeliac disease, so they should have a way to digest it and get the AA. many foods have many allergen inside that cause immune response to those who actually havve food allergy for that specific allergen. but if i dont have allergy and i eat the food with allergen, and the allergen goes intact in the lamina propria without being digested by gut enzyme, how do i get its amminoacid anyway? my body wont waste them? thank you again
@physiopathopharmaco4190
@physiopathopharmaco4190 6 лет назад
There is decreased absorption for those with celiac disease due to morphological changes including Villous blunting and decreased surface area. Some don’t have these morphological changes despite having positive antibodies on a blood test. These may not have issues with absorption.
@tanmaymurur2377
@tanmaymurur2377 5 лет назад
Great video 👌 Isn't dermatitis herpetiformis also a manifestation of celiac disease owing to cross reaction of antibodies?
@jamyd7849
@jamyd7849 4 года назад
Yes it is
@زهراءحسينجباررفيش
@زهراءحسينجباررفيش 11 месяцев назад
رحم الله والديك
@asmajama7947
@asmajama7947 4 года назад
Thank you so much for this amazing explanation🙏🏽
@physiopathopharmaco4190
@physiopathopharmaco4190 4 года назад
You're so welcome!
@xbieberlicious
@xbieberlicious 3 года назад
really nice
@sondosalmadhlouh7872
@sondosalmadhlouh7872 3 года назад
thank you!
@GauravSingh-tx4dt
@GauravSingh-tx4dt 5 лет назад
Sir can you please share the source of information..
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
Much of that came from the Review article "The Role of Gluten in Celiac Disease and Type 1 Diabetes" published in the journal Nutrients.
@Elbuho17
@Elbuho17 2 года назад
BEAUTIFUL !
@xxblackgeishaxx
@xxblackgeishaxx 2 года назад
Thank you so much. I am presenting Celiac Disease for a case study to the Colonel and pathologists in 2 weeks and this helped me better understand exactly what is happening in the lining of the small intestines on a microscopic level.
@khankaseparhnahagee9530
@khankaseparhnahagee9530 4 года назад
Scientist should do something for this
@grizzy315
@grizzy315 4 года назад
khan kase parhna ha gee yes, but there is not enough awareness for most scientists to research on the disease. its sucks but hopefully in the long run treatment is more effective.
@leavesofchange
@leavesofchange Год назад
Does secalin get deamidated by tissue transglutaminase?
@lazymedic5988
@lazymedic5988 6 лет назад
Brilliant..plzz upload videos on bone pathology..ua awsome
@physiopathopharmaco4190
@physiopathopharmaco4190 6 лет назад
Do you have a particular pathology of the bones in mind and Ill get started
@lazymedic5988
@lazymedic5988 6 лет назад
PhysioPathoPharmaco it would b great if u upload video on detailed pathology of osteoarthritis n osteoporosis with complications..plzzz
@nj2147
@nj2147 4 года назад
Thanks a lot..😊😊
@physiopathopharmaco4190
@physiopathopharmaco4190 4 года назад
Most welcome 😊
@Shilaan111
@Shilaan111 5 лет назад
great one thank youuu:))
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
You’re welcome
@NadineBotterman
@NadineBotterman 4 года назад
Is it true that your intestines FULLY heal after a glutenfree diet?
@physiopathopharmaco4190
@physiopathopharmaco4190 4 года назад
Yes but it can take up to at least a year.
@fuscaotunado1337
@fuscaotunado1337 5 лет назад
Can you give us the references you used? @PhysioPathoPharmaco
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
Much of that came from the Review article "The Role of Gluten in Celiac Disease and Type 1 Diabetes" published in the journal Nutrients.
@fuscaotunado1337
@fuscaotunado1337 5 лет назад
@@physiopathopharmaco4190 tks
@هدىعلي-ش1ز
@هدىعلي-ش1ز 5 лет назад
That was great thanks!
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
Thanks glad it was helpful
@matthewhill6949
@matthewhill6949 5 лет назад
Great video. How did you illustrate this? What programs did you use?
@tahiransari3917
@tahiransari3917 5 лет назад
Helpful
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
Thank you Tahir
@khawla-ez6cv
@khawla-ez6cv 5 лет назад
Thanks you
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
You’re very welcome Khawla- all the best to you. 😀
@wem3121
@wem3121 5 лет назад
So the things that get the Disease started is a genetic predisposition of HLA II molecules AND an overexpression of CXC3 cytokines. Is that how it starts? And what about LT that escaped tolerance? Oh is that all those mechanisms at once? Thanks a bunch for the video. Im grateful 😍
@physiopathopharmaco4190
@physiopathopharmaco4190 5 лет назад
Yes several genetic factors can increase the risk - DQ2 and DQ8 and CXC3 cytokine expression
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