Hi- My research suggests that histologically, hypertrophic and keloid scars both contain abnormal amounts of collagen, but hypertrophic scars consist of mainly type III collagen fibers arranged parallel with the skin surface, while keloids contain disorganized type I and III collagen. Overall, keloids have higher collagenase activity, type III collagen, chondroitin 4 sulphate and glycosaminoglycans than normal scars. Keloids show expression of upregulated type I procollagen and unaltered type III procollagen. These changes result in a markedly elevated type I/III procollagen mRNA ratio compared to that in normal skin.
hi dr. moore!! i found you from the noted anatomist. im nowhere near medical school yet, actually soon to be high school student but im teaching myself this stuff and trying to make sense of it from your guys videos and i was just wondering (and im sorry if this is a dumb question), sometimes its more obvious but can you usually tell what plane these anatomical sections are taken from to get a better mental image of the context in the organ as you get better at knowing anatomy?? like whether its coronal, axial, or sagittal kinda thing. thank you for the videos they are really amazingg
@@thehistologywizard5783 thank you so much dr. moore, i have made a goal to watch atleast one of your videos every day and take notes and i am learning well so far!!
