This video will cover nonsense, missense, frame shift, wild type, insertions, deletions, and duplications in the genetic code. DNA codon basics, wobble, and how to interpret DNA code mutations will be covered!
Correction! You are partially correct about MISSENSE mutation. Partially correct because a letter does change but the ending result about the amino acid not changing... It DOES change the AMINO ACID. It can be something else other than histidine. Silent mutation should be part of your bullet points since you described it. Silent mutation DOESNT change the AMINO ACID.
Changing the third base (rightmost) in a codon is actually a SILENT mutation, and not a missense mutation. Codon will still specify for same amino acid, due to wobble rule of codon-anticodon pairing. Missense mutation occurs when 1st or 2nd base in a codon changes into another base, forming a new codon that specifies for another type of amino acid.
In your example for duplication, shouldn't the first codon be UUA and then a duplicated UUA? Since UAA is a stop codon, this example is actually a nonsense mutation instead of a duplication since all codons following the first UAA will be ignored until a start codon is encountered.
Missense and silent are mutually exclusive i Beleive. If Missense then amino acid was changed by nucleotide change, if silent than despite nucelotide change the amino acid was not changed (because of degeneracy).
Purines and Pyrimidines are nitrogenous bases that make up the two different kinds of nucleotide bases in DNA and RNA. The two-carbon nitrogen ring bases (adenine 'A' and guanine 'G') are purines, while the one-carbon nitrogen ring bases (thymine 'T', Uracil 'U' and cytosine 'C') are pyrimidines. ^_^ Hope this explanation is helpful. :) Good day.
RNA has the nucleotides AUGC, not DNA... DNA does not 'read' codons.... Ribosomes bind to mRNA at codons where tRNA binds with its complimentary anti-codon...
Insertions and deletions ARE FRAMESHIFT mutations... they both ruin the reading frame for the entire length of the sequence thereafter... this is going to give students a lot of incorrect information... please edit this to correct the issues.
