Bet you that female egg cells literally just look like Violet from Charlie and the chocolate factory when she started turning into a blueberry, but skin colour instead of purple.
Probably a large round girl? But as far as periods... yeah, I imagine a lot of hopeful female blood cells carrying tons of nutrients, just hoping to see the egg get impregnated, but then... I wonder how does the brain even know when to release the different hormones? How does it even work to have a cycle like that?
@@bluebird1914 Fun fact--the egg can actually choose which sperm to accept. So if there's two competing, it will envelope the one that it wants but reject the other one.
honestly I think their design could've been though out a little better. Like just put some cells on a full-body white suit with the legs becoming the tail, but from waist-up they are still like other "humans".
Tbh if this is their final design, I think it's not just a sperm cell with a head sticking out. The whole cell could be a vehicle and the rest of the sperm's body is inside the sperm head.
I really appreciate Cells at Work: Code Black. Not only is it really educational but also it kinda forces you to be more aware of what kind of lifestyle you have and how it affects your body. And as always, I really enjoy your reactions to these, Dr. Hope! :D
@@rafnavi4500 Even so only one (maybe two if fraternal twins) out of tens of millions will even succeed in fertilization since there is only one (sometimes two) egg cells that exist in a female at a time.
considering the body got an STI it was probably unprotected sex however yeah could've been with someone taking their own birth control or just not ovulating (or could be non vaginal)
"I love the perseverance of this Red Blood Cell. He is making it his personal responsibility to get that erection. That is dedication to the cause. That is what you want in a wingman." This line nearly made me spit out my breakfast laughing.
Having been one of the team originally working on Viagra (although at that time it was just referred to as sildenafil citrate), it was a little sad when the team was disbanded due to some unpleasant side effects when used for its original purpose. The compound was effectively killed off as an R&D project. About a year later, the team was pulled back together again as a few people on the clinical trials had asked to be able to keep taking it as they said it had saved their marriage! I spent the next 5 or 6 years working on this (was a team leader at this point), and wrote a large chunk of the analytical package for the FDA and MHRA filings. Was a great project to work on. Thanks, Dr Hope, for reminding me of that time. Every one thinks that was the biggest drug for Pfizer, but at the time I left, it was only the 6th biggest ( in terms of income). Oh yes, and I think we'd heard all the jokes long before it was approved for use😁
@@whalisten Hi. I studied Chemistry and worked as an analytical chemist in pharmaceutical R&D for around 40 years, for 3 different pharmaceutical companies. It was always fascinating work, working with great people. It was always a fast changing environment, with loads of new challenges.
@@TheSpeegy I bet it was awesome and interesting. But, you as a chemist, worked on R&D with only another chemists? Can you pls tell me what other professionals worked with you
I love how in many episodes, when every cell is celebrating that they got saved by medicine, the brain cell is thinking "yea we got saved, but the fact we needed saving in the first place is pretty bad". It's very foreboding to the habit some people have to seek temporary medication to symptoms of an underlying condition that needs much more serious measures.
From the perspective of someone who hasn't seen the sperm before, any comment on his appearance make me more excited about the episode. Mostly cuz it's so confusing that I can't imagine it
I’m still advocating for a “Cells at Work! Pink” something about the female body. Maybe a red blood cell watching the uterine lining fall like a wall collapsing violently. Maybe the end of the season you see an extended episode on conception and pregnancy. Would be cool.
Nobody wants that because all weebs are young men who think girls are gross. /s But seriously, as an amateur gynecologist, the female-specific issues the show could deal with would be off-putting and would make guys less likely to want to mate, and so nobody with conscience would air it. Japan already has a bit of a problem when it comes to reproduction, and making it worse by showing guys the reality of women and birth wouldn't be celebrated.
@@UnsoberHadrian And….? The more informed a man is about the other side of the equation, the less likely they are to get themselves in a sticky situation. As a “gynecologist”, I’m really surprised that you even sound like you discourage reproductive education of both sexes.
I was thinking it would be a shame if after all that they would end up in a tissue. But considering the venereal disease at the end that doesn't seem to be the case and they probably didn't end up in a condom either.
My theory about bacteria being "out of proportion" is that they don't represent a single bacterium, but more of a colony. Such as the last episode where there was one that was bigger than the WBCs.
The artist actually shared some art about the sperm cells. They're actually dressed in cute little tuxedos inside those capsules, which are somewhat like small submarines.
I want a series that explores the development of a child. It would be neat to see what the cells would be like when the baby is in the womb. Fresh new body and fresh new start. This series is so fascinating.
Cells at Work does a really good job of anthropomorphizing what exactly goes on in the human body, and it shows the struggles that they face day in and out trying to keep the body working as best they can. It's hard not to get invested in their struggle. There's also sly criticism of the chronic Japanese work culture in there as well.
Ah, the episode where Dr. Hope gives us "The Talk." My late biology teacher always explained the epididymis as " a little YMCA where all of the little sperm learn how to swim." It was nice to essentially see that play out in the episode lol
12:47 there's also the fact that the brain being lowkey upset about it, probably means the dude the cells live in, is himself self consious about needing viagra.
While the anime kept itself very mature and grounded in information, seeing the cells saying "you haven't even experienced your first erection" was a hardcore test of maturity for me..... which I failed... miserably xD
Not to mention this little gem from the dub: WBC: “Where are you headed?” RBC: “The testicles.” WBC: “Oh, that’s nuts!” I had to pause the episode for a couple minutes while I paced around and recovered.
Love cells at work and this channel makes it even better, that being said after every episode of Code Black I feel like I have to apologize to my body for the emotional turmoil my cells have gone through due to my uni lifestyle
"Whoever created Cells at Work definitely had a smoke of a few things" It's kind of amazing how incredibly harsh Japan's drug laws and social stigma against drug users are (we're talking to the point that in the manga industry, owning child porn has literally been shown to be LESS career damaging than light drug use), and yet how much manga and anime absolutely looks like an acid-fuelled dream.
I don't know why _either_ ought to be very career damaging. Opium was once sold openly in drugstores even though its addictive properties were known. Addiction was seen as a private medical problem. As for the rather disturbing porn... I'm more concerned that coercion was used to create the material than the material itself. So saying one is worse than another doesn't impress me. Oddly enough, the stigma against drug users was influenced by the west. Specifically, they looked at America in the 60s and 70s and were like "we're better than that" (my speculation is that drug users were associated with dissent) and it evolved to current attitudes. Their modern Whaling practices are came from America. In the Edo and Meiji period whaling was very rare and most whales eaten were those that washed up. After WWII, general Macarthur told Japan whaling was really good and it got a generation of schoolchildren to love whale meat. I could talk about the panties obsession, but that story is rather long.
@@alex_zetsu well, yes, obviously the problem with child porn is that it implies child rape. There is an ongoing discussion and a lot more variety in terms of laws when it comes to _drawn_ child porn - which doesn't involve any actual person - but that wouldn't be punished in Japan. We're talking actual pictures or movies, which imply children being exploited or raped. So obviously even being a "customer" for it means being accomplices more or less directly in its creation, or at least incentivizing it. Either way it's very different from doing drugs, which is a truly victimless crime - a personal choice which however potentially stupid harms no one but the user.
@@alex_zetsu You're just showing how ignorant you are. The Opium Wars started because the emperor saw opium addiction as a national public health crisis and banned it, which pissed off the British. So no, the West didn't invent drug addiction stigma. Singapore is even harsher on drugs and will execute you. Even in the west, addiction was never seen as a "private problem." It was an epidemic among civil war veterans, which is why morphine addiction was known as "the soldier's disease." That's why we had the temperance movement. In fact, it was seen as a feminist issue because men would become addicts and let their families starve. Yes, it used to be sold on store shelves, as was cocaine. It was sold in the form of patent medicine. Alcohol was also prescribed as medicine. It's not sold anymore because the Food and Drug Act outlawed patent medicines and made it so ingredients had to be published. People also used to sell other humans as slaves in the town square, does that make it okay?
I will never not be thankful for the amazing names of the chapters that you do, Ed. They're that beautiful, extra touch that makes the videos even better!
I’m currently waiting for your face masks to arrive! I bought one for me, and one for my sister who works in a children’s hospital. She can’t wait to make her coworkers jealous!
i’ve been loving code black but am always excited for you to review them since i get a little bit lost 😅 love your humor and your touch on everything !
its honestly pretty fun to watch both Cells at Work and Cells at Work BLACK back to back (and they cleverly air in the same day) because you go from a happy-go-lucky body where things are mostly hijinks ensuing and minor issues like scrapes and germs and then you're thrown into this fucked up enviroment where you see all kinds of diseases and a body thats plain nasty on the inside xD
@@MrKlausbaudelaire that’s my favorite thing ! regular cells at work is really cutesy and wholesome and is a comfort show for me, but then i get to watch code black and see what happens when everything goes insane - i love that they’re both coming out together !
About that line at 1:34, I believe that is supposed to be a reference to how unhealthy this body is. We know that due to the smoking there is already a shortage of properly working, living red blood cells and the body's normal cells are already living on rationed oxygen. Since the amount of excess oxygen in the blood is already so low, diverting red blood cells to cause the erection will cause some regular cells to starve for oxygen and die. Which makes us really wonder just how unhealthy this guy must be to have that be true...
I think if getting an erection causes some of your ceels to die... you probably shouldn't really be alive, lol How the hell is this person still living
An erection doesn’t really tie up that much blood. I think the idea was that this person just has bad circulation in general due to poor health, plus stress and anxiety interfering with the mental side of the process.
It's actually brilliant that the sperm cells are depicted as little kids. Sperm cells are ejaculated still immature (and wouldn't be able to properly fertilize an egg cell in that state). They actually mature as they travel along the female reproductive tract.
about the casualties, I thought it might refer to the microwounds that form when this occurs. It can lead to some blood getting out (i.e. the casualties) and is one of the main transmission sources of stds.
Dr. Hope you probably won't see my comment but i just want to say these videos are really fun and interesting and thanks to you now i love studying biology thank you so much❤️
It’s not shown here, but I was initially confused by the scene in this episode when White Blood Cell 1196 shows our main Red Blood Cell to the epididymus, because it was my understanding that leukocytes need to be kept away from sperm. Sperm are different enough from other body cells that the leukocytes can identify them as foreign and attack them. The Sertoli cells are supposed to maintain a so-called blood-testis barrier so a man doesn’t develop antibodies to his own sperm. I was nervous about White Blood Cell being so close to the baby spermies! However, I just realized that the blood cells were only shown the nursery, before the spermatocytes have built their antigens. We -correctly afaik- don’t see blood cells even near the pool with the mature sperm that are ready to be ejaculated. Yay for Cells At Work accuracy!
Fun fact: here in Japan this show is currently aired on Saturdays at midnight, but episodes 3 and 4 were aired at 3 a.m. in the middle of the week (I don't remember if it was a Wednesday or a Thursday).
I think this show is supposed to be for those already experiencing puberty, middle school/high school level. Though I suppose it's still pretty awkward watching this with anybody no matter the age, since this is basically sex ed. It's not like student having sexual activity is something new, in Japan.
So where I work most of our ED patients are actually guys in their prime, many without any noteworthy vices. Most cases turn out to be hormonal and/or psychological in essence, and I do my best to be as kind to the guys as possible considering the stigma of ED is as big in the PRC if not slightly higher than anywhere else. Love your vids Dr Hope!
That reinforces the theory that the person from Cells at Work Code Black, is older than the person from the original Cells at Work. I'm also willing to bet that the person from the original Cells at Work is also a man.
@@Genin99 Oh CaW:CB's setting is definately a past-their-prime dude who gets dragged off to nomikai every other day after work. And everyone knows the original CaW setting is an anime shounen protagonist who got isekai'd in the 1st season finale ;)
Been watching your reviews of these, and enjoying the maturity and education that you add to it. This is a touch subject that can get giggles, but I think this show is handling how the way they present different issues to the human body very well. Honestly, I've been able to retain more information about microbiology through the lens of an anime than in actual biology class. It's presented in the form of something I'm actually interested in and will pay attention to. Being ADHD is rough that way.
I love this series, it allows me to satisfy my curiosity with biology 😀. I hope your all well sir, and tyvm for your time with us. As well as your service 😀
I’ve been so invested in this series thanks to you. Thanks for all the analysis you bring, I’m honestly learning so much just by watching you and the anime.
Could it be that, The Megaloblastic red cell, its just another expression of this particular body being unhealthy, in the previous chapter we saw he has problems with the alcohol and I bet he does not eat healthy (lack of vitamins and minerals), so his red cell production would be affected as well, right?
Hello Doc, can I suggest to you to add part that “episode verdict” ? Like, medical accuracy, animation, music, ... Anyways I’m always fun to watch, thank you!
Cells at Work is GENIUS!!! I can't wait to watch all of your videos with this show. I don't understand why there is a stigma....because without the reproductive system, none of us would be here. The human body is the most amazing thing on this planet.
Hey, I thought of another show that would be interesting for you to look at. It is called Limitless. It is about this guy who takes this drug that allows him to use 100% of his brain. I am kinda wondering how medically accurate it is, theoretically.
I can tell you right now. Absolutely inaccurate. Some already covered this. You are already using 100% of your brain. If you weren't you would be having serious problems.
It is zero percent accurate. The myth of "we only use X% of our brain" (usually cited as 10%) is nonsense. It comes from a gross misunderstanding of a study that showed approximately 10% of our brain cells are firing at any one instant. In reality, the next instant it's a different 10% set of cells firing. We use 100% of our brain. And I've had some people respond to that by saying, "Well, what if we could get 100% of our brain cells firing at once?" That's called a seizure. A massive seizure at that. With every brain cell firing at once, it would be basically guaranteed lethal. Brains work by the patterns of activity they produce; firing everything at once doesn't leave any room for patterns. ...sorry for ranting, I just *really* hate the whole "use 100% of your brain and become super-powered!" myth/trope.
@@IceMetalPunk A good allegory is that your brain is like playing the piano. You press a certain amount of keys in rhythm with each other to create a beautiful song, but if you just bash a large amount of random keys you just get a jumbled mess of noise and it sounds awful.
@@brandonlyon730 That's a good one. I'm a software developer, so the way I always think about it is if you set every bit in a file to 1, you lose all the information that file ever had.
And there is a good reason why all of the brain we have is needed. If we could do with less, we would have less. It takes about 20% of our nutrients, no matter what we do. Having more brain than needed would be a waste of resources that could be saved or used elsewhere. There are even studies that show that over the last 28000 years or so the average brain volume is actually decreasing.
It would be interesting if you could react to The Age of Adaline. It's one of my favorite movies and really want to understand the medicine behind everything.
I think the reason the bacteria and such is shown 'too big' often is to show it's not just a minor encounter, but rather something that's begun to spread and become a legit potential threat to the body. Thus a mini pseudo-whats-it (green one-eye thing) cuz it was a 'regular exposure'. Does that make sense?
I feel weird the fact that they make it so sad that every single ejaculation must have a purpose of reproduction While tbh most ejaculation was not really doing that purpose even for a healthy person And somewhat they shame this act of wearing condom or masturbation
Well, it's kind of inevitable if you anthropomorphise individual cells like this. Even in actual reproduction, only one of those sperms would fecund an egg, at most, anyway. Besides, if every red and white blood cell was some kind of little person there would be SO MANY things we do that just kinda waste their lives... pretty much any time you shed blood by hurting yourself more or less by chance it'd be a little genocide. Not sure about cutting your hair or fingernails since I think those don't have living cells, but something like scratching a scab definitely fits the bill.
It actually does the opposite, by teaching that your body wants to reproduce during sex and the next episode features another consequence of having sex irresponsibly.
There's a field doctor at the Mt Everest base camp who uses Sildenafil to treat medical conditions people get from high altitudes like high pulmonary systolic arterial pressure and hypoxia lmao boner medicine out here keeping the number of people who die on Mt Everest low.
Yes, sildenafil is still occasionally used for non-sexual problems. Still will get you funny looks from a pharmacist if you're a woman taking it for Raynaud's.
I'd love to see your reaction to the TV shows: A Young Doctor's Notebook, and Quacks. They're both hilarious dark comedies which look at what surgery and medicine was like in the past.
omg i love this series!! i love cells at work, but i’m not a medical student (YET.. hopefully) so it’s great having your commentary! i actually understand all the concepts, not just the ones i’ve covered in a-level so far:)
One thing I have been thinking: We know this body is a man and all red blood cells are depicted as men and white cells as women, does that mean that the main show where the white cells where guys and most red cells I remember were women, the body belongs to a woman ?
You missed the part where one cell talks about masterbration and the red blood cell gets sad knowing that all the effort they gave may have zero results
by the way, in the manga the egg cell's design is not looking better either! yes sperm cells look like a single man submarine thingy... the egg cell in the manga looks like a big red balloon of blood with a head sticking out of it! so both of them the designs aren't easy on the eyes...
They did it in Cells at Work, the original series manga. So the other body with the female red blood cell is from a female body. Putting the body approximately at teenage level.
@@Iden_Elihio_1999 The Cells at Work original series manga has a menstrual cycle in it. So that body is female, and apparently, it's the first one, pegging the body in that in their teens about? Also, notice that the protags for each match the physical and mental gender of the body. I kinda have a head canon going that this is what the original body looked like at a fixed age. Like the amount of scrapes, etc the female body goes through is because she's as clumsy as the red blood cell protag. It's also possible given the information we have that the Code Black Body is the father of the other body. lol But that's all head canon there.
Fun Fact: *In the English Dub they actually say "Viagra" and not "Sildebafil".* Also yes I do watch dubbed anime but before all your hate comment come in I want to say I've been watching anime for 32 years. So I don't care about all of your "Sub Only" purist comments. I watch both Dub an Sub and depending on the anime I watch it in both Dub and Sub.
I was wondering what the body for a lifestyle has: he smokes, he drinks, then he pops a pill and procreates. I also haven't seen spörms that have been damaged by alcohol. But i always imagined them riding aquabikes rather than being ducks with human faces. Spörm 1: "Alright! May the best of us win this race, guys!" (revs up his aquabike) Spörm 2: "You bet i will be the one!" Spörm 3: "DERP MY BLUEPRINTS!"
