Double Bohr effect | Circulatory system physiology | NCLEX-RN | Khan Academy

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Learn how there are two distinct Bohr effects happening at the same time in the placenta. Rishi is a pediatric infectious disease physician and works at Khan Academy. Created by Rishi Desai.
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Опубликовано:

6 окт 2024

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Комментарии : 13

@khanacademymedicine 11 лет назад

That's right, the video entitled "Hemoglobin moves O2 and CO2" goes into that in more detail.

@romeolhk1008 8 лет назад

Darn, what a world class presentation!

@lyricson4ya Год назад

This is hands down the best💥

@suppumbbs 9 лет назад

Thank u, its very helpful

@lovekapil4062 6 лет назад

I have a slight confusion. Isn't Bohr effect related to the "decreased affinity" between oxygen and haemoglobin due to "increase in CO2" Or is it defined as vice versa too, as at 9:28 in the video 9:28 starts losing CO2, so O-Hb affinity increases.

@KAST96 5 лет назад

The latter is called Haldane effect. But it does happen.

@peptobismolveins 4 года назад

KAST96 haldane effect is not at all related to oxygen dissociation. It’s about strong acidic nature of oxyhemoglobin which causes release of H+ ion and forms H2CO3 and then that forms CO2+H2O at lungs. It’s about CO2 formation and diffusion at lungs. Bohr effect relates to O2 dissociation (and, therefore, association) at tissues.

@danzeera1451 5 лет назад

I really needed this Video.... Thanks a lot 👍🏻😊

@javeriaiqtidar9776 8 лет назад

Does this blood pool mean that the oxygenated and deoxygenated blood gets mixed with each other?

@ranjithrajan2443 3 года назад

Can't this be also interpreted as double Haldane effect?

@tomterific390 2 года назад

No, because in this case we're talking about the effect of increasing pCO2 and [H+] on Hb affinity for O2. That's Bohr, and it goes on in extrapulmonary tissues. Haldane effect goes on in the lungs, and it's about O2 decreasing affinity of Hb for CO2 and H+. So Bohr is about CO2 and H+ causing Hb to give up O2 (i.e. delivery of O2 to the tissues), whereas Haldane is about the reverse of that, i.e. O2 causing Hb to give up CO2 and H+, IOW delivery of CO2 to the lungs for disposal..