Тёмный

Dr. Karunapuzha on How to Take Levodopa for Parkinson's and Why 

Davis Phinney Foundation for Parkinson's
Подписаться 32 тыс.
Просмотров 86 тыс.
50% 1

Dr. Cherian Karunapuzha gives advice on how to get the most from your levodopa: take it on an empty stomach with a glass of water, and (if possible), one hour before a meal or two hours after a meal.
This content is made possible by the generous support of viewers and listeners like you. If you would like to make a donation, please visit: dpf.org/youtub...
Learn more at davisphinneyfo....

Опубликовано:

 

29 сен 2024

Поделиться:

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист
Посмотреть позже
Комментарии : 75   
@ellagrobler6982
@ellagrobler6982 Год назад
Many thanks for sharing this info.
@davisphinneyfdn
@davisphinneyfdn Год назад
You're welcome!
@ML-zm6kk
@ML-zm6kk 3 года назад
Thank you so much. This video has been more informing than the neurologist I have been seeing for a year. -_-
@davisphinneyfdn
@davisphinneyfdn 3 года назад
We're so glad it has been helpful!
@chriswood3146
@chriswood3146 2 года назад
Is it ok to take gingko biloba when on high doses of Madopar?
@geoffreyiles1519
@geoffreyiles1519 Год назад
Interesting how constipation interferes with your meds. I was very constipated and did not appreciate that I had PD. Thank you for the clarity. As per Elliot Overton I have been working hard at trying to find the”sweet spot” for taking the vitamin B1 and it’s not easy. I have just moved up to 200mgs of B1 nitrate sublingually plus 50 mgs of TTFD B1 and are suffering a relapse as promised. However I can now sign my name and have sufficient stamina to do the dishes without having to sit down every 5 minutes to rest my back extensors and guess what my severe constipation is suddenly gone as promised due to TTFD B1 according to Elliot! I only hope I that I see improvements in other areas as well.
@peterwillis8364
@peterwillis8364 11 месяцев назад
​@@geoffreyiles1519😅p
@peterwillis8364
@peterwillis8364 11 месяцев назад
😅
@toryberch
@toryberch 2 года назад
Thank you Dr, for a clear easy understanding explanation 👍👏
@michaelnametz7176
@michaelnametz7176 Год назад
This is clear, practical advice. Thank you, Dr K
@mdsaharulislam822
@mdsaharulislam822 Год назад
Dear Sir, I have been suffering from parkinson deases from a long time.when I write ,my fingers are troubling.I have take many medicines but do not cure at all.Do I cure it any way ?please help me .
@donaldlivingstone3413
@donaldlivingstone3413 2 года назад
This has been extremely helpful. Thank you.
@Barefoot53
@Barefoot53 6 месяцев назад
its been 7years with pd. from the 1st appt I told the dr i was very constipated , he never once acknowledged my bowels. Im so fustrated with the information and no support for pd within 200km
@davisphinneyfdn
@davisphinneyfdn 6 месяцев назад
We're sorry to hear that you're having trouble finding support nearby. We're here for you. Here is a recent conversation about nutrition wherein a registered dietician, Kristin Gustashaw, discusses constipation and related issues (use the timestamps in the description to find the moment): ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-Z80GEQwmbZI.html
@yiazmat213
@yiazmat213 8 месяцев назад
Would it be even more efficient to add zinc methinone, p-5-p, magnesium taurate and ester-C to the levodopa? (Question referring to both people with and without the disease) And if yes what would be the ideal dosages? And at what time is optimal compared to your meals and the l-dopa?
@davisphinneyfdn
@davisphinneyfdn 8 месяцев назад
There is not, to our knowledge, research backing concurrent use for all people with Parkinson's of the supplements you mention. That said, there may be reason to take these supplements, and each person with Parkinson's should consult members of their individual care team for advice about supplementation. Each person's individual needs will vary.
@michelelindseth8250
@michelelindseth8250 2 года назад
Thank you. This told me more than my neurologist.
@kccheang_SGP
@kccheang_SGP 2 года назад
Very helpful and informative! Thanks
@rajendraagrawlji7521
@rajendraagrawlji7521 Год назад
In Parkinson. Urin. Problem Remidi. Of. This problem
@chuckswaim
@chuckswaim 11 месяцев назад
Great help in explaining things. 😊👍✨
@rolfehlers2101
@rolfehlers2101 11 месяцев назад
Your approach to the problem of choosing the right timte for eating and taking Levodopa is absolutely convincing. You stop the necessary information halfways on the right way, although and in the end come up with wrong conclusions. To do it right you must keep en eye on the timae and mass of proteins. Not only the proteins are to be watched, too much fat keeps the stomach closed for the inlet into the minor intestine. A fat cheeseburger or a luscious steak keep the entrance into the intestines shut and levadopa cannot be digested and transported to th brain. A perfect time to sstart the day with 1 portion of levadopa is the morning after a regular sleeping period. This is the time for your proposed:After taking good glass of water, because then the stomach will be empty for sure. After the consumption of levidopa onto the empty stomach it is also indispesable to watch not t mingle the pill with proteinrich food - just as you describe vory well in this video. I am strikken by Parkinson since appr. 20 years, 82 yrs of age. Most of my life I was practicing lawyer and developer of ways to better the Serotonin level . I followed the reprts of some thousans users of food products that I developed in this interest (onto the empty stomach, naturally). Also I wroe two books on Serotonin and weight control (in German). I am looking forard for your answer. Best regards. Rolf Ehlers, 41143 Jüchen, Germany..
@davisphinneyfdn
@davisphinneyfdn 11 месяцев назад
Thanks for your message. There are indeed many factors that affect medication absorption and timing of doses. Dr. K.'s advice is to take your levodopa on an empty stomach and to take it with a full glass of water to have the best chance for maximal absorption. Of course, this may not always be feasible or sufficient. Constipation, gastroparesis, and metabolic issues can affect levodopa absorption, and due to nausea it is some people have a better experience if they take levodopa with a small amount of food. Ultimately, each person should follow the recommendation(s) regarding medication timing provided by the person who prescribed the medication.
@mrsgrandmom1503
@mrsgrandmom1503 2 года назад
Hi Dr thanks.can a PD patient survive wit out taking treatment wit levodopa?
@JeffAnm8r
@JeffAnm8r Год назад
Gastroparesis/slow gastric emptying is another PD issue that messes with getting the pills to the small intestine.
@davidwend9229
@davidwend9229 Год назад
Very clear explanation of Levodopa consumption and its assimilation. I will work harder at making sure I stay regular. Will return to a regiment of Metamucil and proper hydration. Thanks
@myvoicespeechtherapy
@myvoicespeechtherapy Год назад
Such a great message - the WHOLE video!
@lisacox9062
@lisacox9062 Год назад
Thank you so much! I take on a empty stomach and wait to eat. I just started taking 4 weeks yesterday. ✨🙌🏽 flaxseed helps with back up.
@davisphinneyfdn
@davisphinneyfdn Год назад
Keep it up! Thanks for your comment.
@ahc1957
@ahc1957 2 года назад
What if you take Leva-dopa like an enema or a suppository? I would seriously like an answer to this question. What if it is taken without protein. PS It seems that I am starting Parkinson’s. In the testing process to confirm or deny but it doesn’t look promising.
@thelmacandid8530
@thelmacandid8530 2 года назад
My cold sores and herpes virus was permanently cure by doctor Ehimare on RU-vid. God bless you your Dr Ehimare and stay safe everyone.
@tranquil4353
@tranquil4353 Месяц назад
Very precise and informative.you cleared many of my doubts for my mom's condition.
@luanndavis-jindela3223
@luanndavis-jindela3223 3 года назад
Best explanation I have heard!
@christileneabrahams6416
@christileneabrahams6416 7 месяцев назад
Don't know if this was mentioned but hormones provided by female parts like the uterus protect a little against artritis.
@jagdishbhai7680
@jagdishbhai7680 3 года назад
Thanks best
@cindypacker3161
@cindypacker3161 3 года назад
Clearest explanation, thank you
@richardgonick931
@richardgonick931 Год назад
Great video. The Dr. spoke to us not at us in basic terminology.👍
@nylene25
@nylene25 2 года назад
Thank you!! Very helpful explanation
@mahuateng1496
@mahuateng1496 2 года назад
Inbrija is great for off periods
@masudulhaque7083
@masudulhaque7083 7 месяцев назад
My father has been suffering in Parkinson disease from last 8 month, Now he can't eating and speaking, What will be the best treatment for him
@davisphinneyfdn
@davisphinneyfdn 7 месяцев назад
Thanks for your message. A speech language pathologist is often the best provider to help with difficulties eating and speaking. You can search a database of US-based providers at this website: find.asha.org/pro/#sort=relevancy&f:@provider=[Speech-Language%20Pathologist] However, being unable to eat may require more immediate attention. We recommend talking with your father's care team as soon as possible to determine the best course of action.
@marklafever5679
@marklafever5679 2 года назад
O
@MDMB53
@MDMB53 3 месяца назад
Informative and helpful. But very hard to practice when you have both IBD and Parkinson's.
@davisphinneyfdn
@davisphinneyfdn 3 месяца назад
Having multiple health issues is a real challenge for most people with Parkinson's. When digestive issues interfere with oral medications, it may be worth considering other interventions like Duopa, Deep Brain Stimulation, or Focused Ultrasound. Also, there are two continuous infusion levodopa systems that may be approved in the US in the coming months.
@annepaulinedl9038
@annepaulinedl9038 6 месяцев назад
Hello, Would like to ask if Madopar can be taken 15minutes before and 15minutes after the prescribed time? Thanks.
@davisphinneyfdn
@davisphinneyfdn 6 месяцев назад
Unless your medication management of Parkinson's symptoms is very complicated, 15 minute variations from a schedule are unlikely to be particularly problematic. In fact, skipping a dose entirely could have more significant effects than taking a dose early or late. That said, this is a question you should discuss with the prescribing physician. There may be reasons the prescribing physician would recommend keeping a more rigid schedule in your situation. For one thing, keeping a schedule often helps people avoid missing doses by accident. Still we have heard from many people with Parkinson's whose physician advises flexibility with medication timing to avoid complicating meal schedules or other parts life, especially in the early stages of Parkinson's.
@rosemaryclarke6250
@rosemaryclarke6250 7 месяцев назад
I thought levadopa went straight to the brain and not the gut, through the bloodstream. Also, no matter how much fibre or laxative I take I never have consistent bowel movements and never had in my entire life , from birth onwards.
@davisphinneyfdn
@davisphinneyfdn 7 месяцев назад
Thanks for your comment. Oral carbidopa-levodopa is mostly absorbed in the small intestine, and thereafter it crosses the blood brain barrier. Here is an article about gastrointestinal issues related to absorption of levodopa: onlinelibrary.wiley.com/doi/full/10.1111/ene.15734
@monicaleguma6979
@monicaleguma6979 3 года назад
Please keep the Mic close to your mouth cannot hear on taking levodopa
@thaha.m.kkorisseri1436
@thaha.m.kkorisseri1436 5 месяцев назад
Which Syndopa is strong dose. Syndopa cr 125mg or Syndopa plus 125 mg
@davisphinneyfdn
@davisphinneyfdn 5 месяцев назад
Syndopa appears to be a formulation name for carbidopa/levodopa in some parts of the world. In the US, where the Davis Phinney Foundation is located, we are more familiar with the brand Sinemet (and its generic formulations). That said, it appears that Syndopa CR is a controlled release formulation, while syndopa plus is an immediate release formulation. If this is accurate, then neither is "stronger" than the other: they both contain the same amount of medications. However, it also appears that the medications are both available in different strengths. You might find this blog post informative: davisphinneyfoundation.org/levodopa-formulations/. In particular, the descriptions of Immediate-Release Sinemet and Controlled-Release Sinemet may be the most relevant to your question. Note that controlled-release formulations are intended to extend how long each dose lasts, but because of this, people taking controlled-release formulations are sometimes advised by their doctor to take both immediate-release and controlled-release formulations. We recommend you consult with a physician or pharmacist who is more familiar with the syndopa brand and formulations for more information.
@cherylmailloux9647
@cherylmailloux9647 Год назад
I understood everything he said and it makes total sense ❤😊
@DianneGething
@DianneGething Год назад
Thank you I understand so much better now.
@zampuii3805
@zampuii3805 Год назад
How long (hour)can work levodopa?
@edithto2142
@edithto2142 Год назад
thank u for the elaboration on this important subject!
@sidheswarankumaraswami3736
@sidheswarankumaraswami3736 2 года назад
Good.Gives me hope to continue my lifestyle comfortably.
@sylviakan8934
@sylviakan8934 2 года назад
One hour before meals 2 absorb first
@TheReggie1970
@TheReggie1970 Год назад
Great informacion thanks alot
@carolharr5203
@carolharr5203 Год назад
Not enough volume.
@debkennedy8013
@debkennedy8013 Год назад
Does this medication help with head tremors?
@davisphinneyfdn
@davisphinneyfdn Год назад
Tremor can be difficult to treat, but levodopa can help with some head, face, and neck tremors. Here is an article that discusses this subject with a focus on facial tremors. pubmed.ncbi.nlm.nih.gov/27470304/#:~:text=Facial%20tremors%20response%20to%20acute%20levodopa%20challenge%20showed%2092%20%25%20sensitivity,an%20early%20sign%20of%20PD.
@mattkeenetile
@mattkeenetile 3 года назад
My current, (soon not to be) neurologist told me when I asked about taking my carb/lev with food that, “ It makes little difference whether you take it with food or not” Thanks
@helensmith8325
@helensmith8325 2 года назад
I have read everything all over the map. will proceed with this recommendation from now on.
@timball3026
@timball3026 11 месяцев назад
He’s great
@davisphinneyfdn
@davisphinneyfdn 11 месяцев назад
We agree: Dr. K. is great!
@multivenkataramanan
@multivenkataramanan Год назад
Thank you doctor for the clear understanding of the medication
@gauravworld2968
@gauravworld2968 2 года назад
That was very nice of you to explain it in detail.
@gregorybalchunas3895
@gregorybalchunas3895 3 года назад
Power of prayer
@RAINYDAYS00505
@RAINYDAYS00505 3 года назад
THANK YOU! Levodopa makes me violently vomit, to exhaustion. We uped the carbidopa which helped but not always. I thought taking it with food would be better. I will try water and pill.
@kathaysong5377
@kathaysong5377 Год назад
Wow. FINALLY someone who gives a clear answer to my questions!! Thanks!!!
@davisphinneyfdn
@davisphinneyfdn Год назад
Glad it was helpful!
@hurain-sv8wy
@hurain-sv8wy Год назад
If someone have symptoms of tremor in one hand, slurring of speech, constiparion, masked face What will be the diagnosis?? Is it parkinson disease? What will treatment ??? Is carbidopa / levodopa before or after meal????
@davisphinneyfdn
@davisphinneyfdn Год назад
The common recommendation for timing Carbidopa/Levodopa is to take it before eating, but follow the advice of the prescribing provider. Some people experience nausea if the take C/L on an empty stomach. As for your questions about diagnosis and treatment more generally, these questions are best asked of a healthcare provider.
@jenixav
@jenixav 2 года назад
Seriously clear explanation on taking the med and daily clearing of stomach to see the result. Tq Dr.
Далее
Офицер, я всё объясню
01:00
Просмотров 4 млн
Urinary Dysfunction and Parkinson's with Arun Mathur
34:14
Walk more normally with Parkinson's - 4 simple ways
5:05
Ask the MD: Myths about Levodopa
4:47
Просмотров 94 тыс.
Decoding Parkinson’s Subtypes
50:44
Просмотров 10 тыс.
World Leading Physician View On ADHD: Gabor Mate
12:08
Просмотров 945 тыс.