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EP 90: Metformin, Berberine, Dihydroberberine: Which One Is Best? 

Shawn Tassone, MD, PhD
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In this episode Dr. Shawn Tassone discusses the use of metformin, berberine, and dihydroberberine for weight loss in women, particularly those in perimenopause and menopause.
He explains that while GLP-1 medications like Ozempic and Monjaro are effective for weight loss, some women may prefer to try metformin, berberine, or dihydroberberine due to concerns or fear of injectable medications.
He provides an overview of each medication, including their uses, dosages, side effects, and cost. Dr. Tassone also discusses the differences between berberine and dihydroberberine, and why he prefers dihydroberberine for weight loss. He also emphasizes the importance of consulting with a doctor and monitoring labs while using these medications.
Episode Highlights
- Why Metformin, berberine, and dihydroberberine are medications/supplements that can be used for weight loss
- Why some women may prefer to try metformin, berberine, or dihydroberberine
- How Metformin can be beneficial for women with polycystic ovarian syndrome.
- Benefits of Berberine
- The difference between Berberine and Dihydroberberine
- The importance of consulting with a doctor, monitoring labs, and cycling off these medications/supplements periodically.
- Cost difference between Metformin, berberine and dihydroberberine
- How personal preference plays a role in choosing between metformin, berberine, and dihydroberberine for weight loss
- Why you should avoid supplements advertised as similar to GLP-1 medications
Resources
Dr. Shawn Tassone's Practice | Tassonemd.com
Dr. Shawn Tassone's Book | Tassonemd.com/hormone-balance-bible
Dr. Shawn Tassone's Integrative Hormonal Mapping System | Tassonemd.com/quiz
Medical Disclaimer
This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.

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15 май 2024

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Комментарии : 36   
@MichaelV369
@MichaelV369 Месяц назад
Are you my doppelganger? My wife and I thought this was an A.I. image of me.
@robinham2796
@robinham2796 2 месяца назад
Finally got the book!!! You are a hero for women!! I took your list to my new hormone doctor and she said, we will test what YOU want to test!! She’s a NAMS doctor and I think she’s a good one!!!! Thank you Dr Tassone…
@johnkelly6265
@johnkelly6265 Месяц назад
Thanks ,great information!
@nerylabrador2861
@nerylabrador2861 Месяц назад
I stick to berberine forever. It has been a miracle pill. Very satisfied with this supplement.
@ericachavis8853
@ericachavis8853 17 дней назад
What results do you have?
@mellie_mel72
@mellie_mel72 2 месяца назад
I tried Berberine last year to see if it would help my cholesterol levels. I eased into it with one pill a day (600 mg) for a week and two a day (1200 mg) the next week so I could see if I had side effects, which I never did. Over a period of 8 months my total cholesterol went from 200 down to 178. Triglycerides went down from 152 to 103. It didn’t do much for good or bad cholesterol though. I also did not see any weight loss on 1200 mg. When I started taking 1600 mg ( 3 a day) I lost 5 lbs, I cycled off shortly after, so not sure how effective it really is for losing more weight. I cycle off for about 4-6 weeks. I have less bloating on it. It does suppress your appetite and less cravings for sweet food. An interesting note is my PCP had never heard of Berberine.
@ShawnTassoneMDPhD
@ShawnTassoneMDPhD 2 месяца назад
It’s great stuff
@salviaprezzemolo2165
@salviaprezzemolo2165 2 месяца назад
@@ShawnTassoneMDPhD Have you seen it lower LDL?
@mellie_mel72
@mellie_mel72 2 месяца назад
⁠​⁠@@salviaprezzemolo2165 No, it only went from 137 to 121.
@salviaprezzemolo2165
@salviaprezzemolo2165 2 месяца назад
@@mellie_mel72 A modest reduction, but my LDL is reading at about 200. Every little reduction helps. Thank you for letting me know. I appreciate the response. I wonder what @ShawnTassoneMDPhD has seen among his patients.
@privateeyeagent194
@privateeyeagent194 18 дней назад
My Dr just started me on Metformin a couple weeks ago (off label for wt loss... I'm 66, have been post menopausal for 19 yrs, have no sugar problems & I eat Keto. I don't drink soda or alcohol & don't eat processed or fast food or at restaurants. AND since I'm just under 5', every extra pound shows 😬). I have Berberine but have never seen any difference with it.. I only just recently learned about Dihydro Berberine. My Dr had never heard of Berberine 🙄 I haven't lost anything yet since starting Metformin (other than my "normal" .5-1# daily fluctuations), but he eased me into it to help prevent side effects. I started whole 500mg tablets bid yesterday... Gosh I hope this works! I am desperate to the lose 40-45 pounds I've slowly gained over the last 30ish years 😢
@roxanalabode
@roxanalabode Месяц назад
Can you please do a video on Tirzepatide Vs. Semaglutide? 💜💜💜
@rogerwilliamjefferson7490
@rogerwilliamjefferson7490 Месяц назад
Please need a link to the endurance supplement. Thanks
@sblaising1
@sblaising1 2 месяца назад
I am concerned about using berberine because I have blood pressure that hovers around 90/60 almost every other day and sometimes goes into the 80's. I definitely don't want it any lower. Would this be a contraindication? Most people don't have to be concerned about low blood pressure.
@LaLunaSkinandBody
@LaLunaSkinandBody 2 месяца назад
Can you add a link to your book?
@annac6066
@annac6066 2 месяца назад
Dr Tassone- Do you recommend any of these options (or other options ) for women who are over weight with metabolic syndrome or prediabetes who are trying to lose weight and are trying to conceive (TTC). You mentioned no berberine for pregnancy or breast feeding women but what about those trying to optimize weight to improve fertility?? You mention in most your podcasts your focus is perimenopause and menopausal women but do you consult for women TTC? Or do you recommend any specialists who CAN consult with women who are TTC? Infertility rates are rising& many women who are TTC are looking toward holistic approaches to help them. Thanks for any help you can offer!
@Painting1959
@Painting1959 2 месяца назад
I had a partial hysterectomy and they never gave me any hormones. I see my gyn should I ask for some. I’m 65 and my ovaries hurt. This was at a young age after my third child…but having problems.
@glamlife8176
@glamlife8176 16 дней назад
What are your thoughts on taking Berberine with a GLP1? Or with Repatha?
@trinagreenfield5198
@trinagreenfield5198 2 месяца назад
4:00AM, perfect time! May I ask what time zone? I just Googled Texas, and I'm guessing it's central time zone. (PST here)
@ShawnTassoneMDPhD
@ShawnTassoneMDPhD 2 месяца назад
We are CST yes
@jesseepudu5037
@jesseepudu5037 21 день назад
Can metformin be taken at the same time wth turmeric black paper at the same time
@jesseepudu5037
@jesseepudu5037 21 день назад
I have been on metformin n igot change in my nails weight loss anemia How can I adress it
@forsalebymb
@forsalebymb 2 месяца назад
I have had a radical hysterectomy in 2005 and been on Metformon since. I also take it because diabetes in in my family on both sides so dr told me it helps prevent that too. I have had no problems what so ever on Metformon and had no side effects. I also take B12 shots once a week.
@scoobybopbop
@scoobybopbop 2 месяца назад
Do you prefer the Epic endurance dihydroberberine product? Why is it tag as glucovantage? Does it means its a conconction of several ingredients??
@lisetteaguilar105
@lisetteaguilar105 Месяц назад
I saw that too and was wondering the same thing
@esoteric.breadcrumbs.
@esoteric.breadcrumbs. Месяц назад
I saw less expensive supplements with the same labeling.
@kenoshakat916
@kenoshakat916 23 дня назад
The Endurance Company’s Dihydroberberine has vegetable wax (rice brand and/or carnauba), isomalt (vegetable), stearic acid (vegetable), magnesium stearate (vegetable), and silica. Am I looking at the wrong Endurance brand?
@ShawnTassoneMDPhD
@ShawnTassoneMDPhD 23 дня назад
Nope that’s it
@kenoshakat916
@kenoshakat916 20 дней назад
@@ShawnTassoneMDPhD aren’t those considered fillers?
@cindiesue1
@cindiesue1 11 дней назад
@@ShawnTassoneMDPhDhi dr Shawn I’ve been taking 100 mg berberine for years not to lose weight but heard good for keto diet. I started on metformin a mo th ago 400 2 x day. No side affects nor weight loss I’m still taking berberine Should I start taking more berberine 2x day along with metformin? Should I only take one or tge other? Should u start taking more mg of metformin? Should I change my berberine to the new one along with metformin? Thanks for your help I’m 70, 5’4 140 lbs
@trinagreenfield5198
@trinagreenfield5198 2 месяца назад
This isn't aimed at the west coast. I'll catch you at a different premiere. I'm loyal, but 2AM is just not in the cards for me. (WA)
@ShawnTassoneMDPhD
@ShawnTassoneMDPhD 2 месяца назад
Not sure what you mean
@trinagreenfield5198
@trinagreenfield5198 2 месяца назад
Good morning. I’m actually watching this now. Wonderful and very insightful. My apologies for the confusion. I just didn’t want to miss this but it started at 4AM CST. I’m over here in the state of WA, and being with it live would have meant waking up at 2AM. But regardless, I’m watching it now and it’s terrific information. I hope you have a productive day!
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