Amide local anesthetics play better therapeutic profile over ester local anesthetics in many aspects but still they can produce more toxic reactions than ester derivatives. In this video, the main differences between these two categories were discussed in detail.
#localanesthetics
#lidocaine
#benzocaine
0:00 Introduction
0:08 Groups in Local anesthetics
0:49 Types of local anesthetics
1:14 Ester and Amide LA
2:38 Differences
2:57 Acid dissociation constant (pka)
6:52 Onset of action
9:47 Chemical stability
13:07 4. Hypersensitivity
13:46 Drug interactions
15:08 Tissue toxicity
16:29 Ester LA
6 авг 2024
