Evaluating the future role of VEGF inhibitors in pancreatic cancer 

Salwan Al Mutar, MD, UT Southwestern Medical Center, Dallas, TX, comments on the potential role of VEGF inhibitors in managing pancreatic cancer. Nintedanib, an oral kinase inhibitor targeting VEGFR, PDGFR, and FGFR, was shown to have encouraging efficacy, and was well tolerated in a Phase Ib study (NCT02902484). It additionally had low rates of VEGF inhibitor-related adverse events such as hypertension. This interview took place at 2024 European Society for Medical Oncology (ESMO) Gastrointestinal Cancers Annual Congress in Munich, Germany.
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