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Everything You Need to Know About Bupropion (Wellbutrin Review, Bupropion Side-Effects, Uses, MOA) 

Psychofarm
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Everything you need to know about bupropion is covered comprehensively in our thorough Wellbutrin review, which delves into bupropion side-effects, MOA, and more).
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This video is a comprehensive Wellbutrin review covering its indications, mechanism of action, everything you need to know about bupropion side-effects, and more. The FDA approved indications for Wellbutrin (bupropion) include major depressive disorder treatment, seasonal affective disorder medication, smoking cessation aid (marketed as Zyban), and weight loss when combined with naltrexone (Contrave) or dextromethorphan (Aplenzin).
As a norepinephrine and dopamine reuptake inhibitor (NDRI), Wellbutrin's mechanism of action involves inhibiting the reuptake of these neurotransmitters. Common Wellbutrin side-effects include dry mouth, nausea, headache, insomnia, and tremor. More serious potential bupropion side-effects are seizure risk, sjs (Stevens-Johnson syndrome), hypomania/mania, blood pressure elevation, and increased suicidal thoughts/behaviors in youth.
Important Wellbutrin drug interactions to consider include CYP2D6 inhibition affecting codeine, beta blockers, and atomoxetine metabolism. Caution is advised with MAOI combinations due to hypertensive crisis risk from increased catecholamines. Wellbutrin's active metabolites like hydroxybupropion contribute to its therapeutic effects. Overall, this comprehensive Wellbutrin medication review covers key aspects for prescribers.
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#depression #psychopharmacology #adhd
Chapters:
00:00 Psychofarm is a Perfect Place for Shade
00:09 It's not Buproprion
01:23 Indications
03:40 Formulations and History
09:09 Mechanism of Action
14:53 Side-effects
18:35 Metabolism / Metabolites
19:25 Drug drug Interactions
22:12 Outro

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21 июл 2024

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Комментарии : 81   
@osamaazizieh5907
@osamaazizieh5907 Год назад
Please just don't stop. We (psychiatrists) really need your videos
@PsychoFarm
@PsychoFarm Год назад
Not stopping, just starting
@bretgallihugh4723
@bretgallihugh4723 Год назад
Really good videos. Appreciate your service to our education!
@PsychoFarm
@PsychoFarm Год назад
🫡
@vedatzorro
@vedatzorro Год назад
My doctor said that, Wellbutrin inhibits more dopamine than noradrenaline. He said actually it's very week noradrenaline inhibitor. Instead of noradrenaline it works on dopamine. This is what my doctor said
@Gloriaglo0502
@Gloriaglo0502 11 месяцев назад
Thanks for the easy break down. ❤
@samppw
@samppw Год назад
man i also always thought it was buproprion i'm so glad i'm not alone
@jamieholmes1287
@jamieholmes1287 11 месяцев назад
I love you already! Your great!
@user-qs5pd8ig3l
@user-qs5pd8ig3l Месяц назад
Thanks! Simply said.. Sorry for grammar errors, i am from Europe. In my country we still do not have so many variations of the drug as bupoprion.., actualy we have only wellbutrin. For now ... Thanks for all information and education. Most important is what U say at the end of the video. For me, at least... Thanx and b.ok
@MrDaymee
@MrDaymee 10 месяцев назад
Excellent content. Thank you
@maxwell6898
@maxwell6898 2 месяца назад
Okay with the Jung deep end joke I had to log in and say: good channel good sense of humor I loved psychopharm (basic, wikipedia) when I was in my late teens and doing drugs, and now I'm in my late 20's trying to find a way to not kms using a lot of the same knowledge and the help of my psychiatrist. Thank you
@PsychoFarm
@PsychoFarm 2 месяца назад
Much appreciated! I’m almost there already…
@CaptainWrinkleBrain
@CaptainWrinkleBrain Год назад
Thank you SO much for that info on vortioxetine + bupropion! I’ve been looking everywhere for data on combining them (given their interaction) and now I know the suggested max of vort is 10mg in combo. Can you PLEASE cover Vortioxetine in a stand-alone video? It hits so many receptors and it’s so interesting.
@PsychoFarm
@PsychoFarm Год назад
It will certainly be a while, but will hopefully eventually get to it
@jpie78
@jpie78 Год назад
Amazing video!!! And youre a stud muffin
@squashbrowns
@squashbrowns Год назад
i wish he could be my psychiatrist
@gaijingamenetwork8095
@gaijingamenetwork8095 Год назад
Thanks for this!
@PsychoFarm
@PsychoFarm Год назад
You are welcome!
@Moorddeus
@Moorddeus Год назад
Great video! Made me laugh a few times!
@PsychoFarm
@PsychoFarm Год назад
Thanks!
@Stormy_Dawn
@Stormy_Dawn 2 месяца назад
Dig this video. Thank you!
@PsychoFarm
@PsychoFarm 2 месяца назад
Much appreciated!
@IcyHedgehoger
@IcyHedgehoger Год назад
You are the most precious psychiatrist.
@PsychoFarm
@PsychoFarm Год назад
(❁´◡`❁)
@JaysAnatomy101
@JaysAnatomy101 6 месяцев назад
Howdy boss. Will I be blessed to hear you talk about Zuranolone in a future video? Cheers :)
@PsychPA
@PsychPA 10 месяцев назад
Love your videos!! 😁🔥
@elizabeth00653
@elizabeth00653 6 месяцев назад
Is there a benefit in taking more than 300 mg in terms of dopamine and focus? Such as the max dose 450 mg
@811see
@811see Год назад
Nice; can you do a AED series, like you did with the antidepressants. I like your input on medicines; for example low dose quetiapine is basically a glorified antihistamine.
@PsychoFarm
@PsychoFarm Год назад
Maybe one day in the very far future but neurology is not my specialty so will probably stick to the psychiatric component of things
@markhor1988
@markhor1988 Год назад
How common is balding as a side effect? I see it online but doctor and others never mentioned it.
@Iris_Crypts
@Iris_Crypts Год назад
In following on from the moa diatribe, if you look at the effect of antiseziure drugs as mood stablisers, is it then assuming wrong that an ndri with seziure risk is contraindicated for bipolar mania 🤔 Also I saw somewhere that Bupropion increases plasma levels of reboxetine multiple fold but it wasn't the best source and you won't find it in the literature. Make of that what you will but worth putting out there. Ritalin isn't used as antidepressant anymore. I wondering if subjective mood scores would be equal for equal DAT blockade in ritalin vs Bupropion. More over I am wondering why ritalin doesn't have the same seziure risk as Bupropion?
@pennwoman
@pennwoman Год назад
Great.
@ashleyzeleznik5388
@ashleyzeleznik5388 10 месяцев назад
I love your video's hehe
@suppressiontest6372
@suppressiontest6372 Год назад
*Money tree playing* yep this is gonna be a good Psych video
@PsychoFarm
@PsychoFarm Год назад
That's just how I feel
@nathanielfestinger9754
@nathanielfestinger9754 Год назад
I thought it was 'bupropRion' too. New mandela effect!
@mariaelizabeth1794
@mariaelizabeth1794 11 месяцев назад
No offence but as someone with adhd this video was very difficult to watch. Too much side chatter just get to the point 😅
@Tren619
@Tren619 9 месяцев назад
Don’t watch it then, smarty
@taaayll
@taaayll 9 месяцев назад
Wow. Brutal. Just let the man enjoy himself.
@mistymorgan8068
@mistymorgan8068 6 месяцев назад
Just watch it at 1.25 speed 😅
@pockyeatingpanda
@pockyeatingpanda 6 месяцев назад
As someone with depression this video was actually enjoyable to watch lol
@TheJoncic
@TheJoncic 3 месяца назад
Sounds like you just couldn't understand it. Tik tok probably has shorter videos that might help you.
@Mikielma1
@Mikielma1 Год назад
Since you didn't list spongiform degeneration as a side effect, you know it's bupropion and not "buproprion"! Thank you for another awesome vid!
@plockacherrys5765
@plockacherrys5765 Год назад
source?
@maestro9765
@maestro9765 Год назад
@@plockacherrys5765 It's a joke. Prion = causative agent of spongiform dementia
@PsychoFarm
@PsychoFarm Год назад
😂 this one took me a sec
@maestro9765
@maestro9765 Год назад
@@PsychoFarm Can modafinil improve visual memory?
@Strange_Brew
@Strange_Brew 5 месяцев назад
Back 50 years ago, we just called these guy’s mamas boys. Now we have all these scientists involved and plenty of medications..
@ashkan3901
@ashkan3901 9 месяцев назад
you got a linkedin?
@nkonfya
@nkonfya Год назад
the guy that smells like cabbage on the subway told me its pronounced Buproprion..so we had it right all along
@PsychoFarm
@PsychoFarm Год назад
And now I smell like cabbage
@dodgdurango6128
@dodgdurango6128 11 месяцев назад
All I have on this drug is insomnia and anxiety. I hate it so far.
@mechagojira6951
@mechagojira6951 Год назад
Non boring....u sound comatose!!!!! Tu for the info😮😮😮😮
@leannawhetton6328
@leannawhetton6328 9 дней назад
Made me gain weight i think i am the only one ha ha. Still take it as it has helped me.
@Cslice1016
@Cslice1016 Год назад
"con-tra-vay" lol is it intentional at this point
@PsychoFarm
@PsychoFarm Год назад
One never knows
@Gloriaglo0502
@Gloriaglo0502 11 месяцев назад
New subbie here.
@PsychoFarm
@PsychoFarm 11 месяцев назад
Much appreciated!
@bmitidieri
@bmitidieri Год назад
Your videos are great but you should get a better mic. Still Love them though
@PsychoFarm
@PsychoFarm Год назад
Audio on next vid will be better I pinky promise
@Xaichotic
@Xaichotic Год назад
I still say "Buproprion" to this day lol
@kenhaze5230
@kenhaze5230 Год назад
I literally learned today propanolol is not propanolol; it's propranolol. Subtracting "r"s is just as bad as adding them.
@maestro9765
@maestro9765 Год назад
@@kenhaze5230 Yeah I was calling it that for years. Also "sertaline".
@maestro9765
@maestro9765 Год назад
And "Risperidal"
@PsychoFarm
@PsychoFarm Год назад
Me too Shane, me too
@avelione
@avelione Год назад
You look exactly like your voice
@PsychoFarm
@PsychoFarm Год назад
Interesting 🤓
@BrownBarbie22
@BrownBarbie22 Год назад
This is actually the most boring…
@PsychoFarm
@PsychoFarm Год назад
☺️ Thanks for taking the time to comment
@kobebryant-cl7ul
@kobebryant-cl7ul Год назад
Does Wellbutrin feel at all like adderall??? I just came off adderrall due to to horrible side effects…too much anxiety, sweating, sleeping, and physical tension I just couldn’t handle anymore….after taking for 10 years. My anxiety is so much better off adderrall but all other symptoms like lethargy and depression are back full force. I’m worried that Wellbutrin will cause similar side effects and increased anxiety. Should I be??
@zoemzkk
@zoemzkk 10 месяцев назад
Ur so funny😭
@intrepid_rain
@intrepid_rain 5 месяцев назад
Yeah. Leaving the video now, it’s been about 1.5 minutes. I already know I can’t finish listening to you, sorry. Way to click bait. Boring is an understatement.
@MatthewCarter-bn1dr
@MatthewCarter-bn1dr 7 месяцев назад
Way too mumbled. Learn to pronounce the names. Very unreliable information if the presenter can’t even speak clearly.
@Suitswonderland
@Suitswonderland Год назад
When they released the bupropion/DXM formulation it helped solidify my combination using another SERT compound with far less side effects, 450mg 24hr release + Chlorphenamine 4mg x 3/4 a day, also <a href="#" class="seekto" data-time="817">13:37</a> did you screenshot wikipedia? Really hope you never used wikipedia as a source of information within your video, you would lose marks in the test (thumbs down).
@plockacherrys5765
@plockacherrys5765 Год назад
youre not a dr? wiki has references. ive used it
@Peace4globe851
@Peace4globe851 6 месяцев назад
You sound very unsure about what you are talking about. Sorry. I had to say it.
@xXxC0nSUm3rXxX1337
@xXxC0nSUm3rXxX1337 Год назад
I for some reason, thought this channel was mainly about drug pharmacokinetics, pharmacodynamics lol
@dietitiandaddy
@dietitiandaddy 3 месяца назад
Contrave, pronounced like the a in IPA
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