We show how to start building an atomic model into a cryoEM map using an atomic structure from the AlphaFold database. We fit the atomic model into the map and adjust the position of one of its domains. The map is EMDB 30495 and is of a human dimer originally thought to be an mechano-sensitive ion channel, although the Nature publication speculates it is instead involved in lipid metabolism.
24 авг 2024