Fluorescence insitu hybridization [ FISH ] | Made easy | Physical mapping | Bio science 

Fluorescence in situ hybridization (FISH) is a kind of cytogenetic technique which uses fluorescent probes binding parts of the chromosome to show a high degree of sequence complementarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosome. This technique provides a novel way for researchers to visualize and map the genetic material in an individual cell, including specific genes or portions of genes. It is an important tool for understanding a variety of chromosomal abnormalities and other genetic mutations. Different from most other techniques used for chromosomes study, FISH has no need to be performed on cells that are actively dividing, which makes it a very versatile procedure.
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