General Embryology - Detailed Animation On Fertilization 

There is a major mistake in this video. At 0:50 the cell has two polar bodies. Note that one polar body is produced after the first meiotic division and the second polar body after the second meiotic division, which is only completed once fertilization occurred.

A complete and efficient video! Very well explained, thank you!

Perfect channel to learn embryology!!! Please make more videos!! Thank you so much .... You are really helping many med students!👏👏

Your channel deserves more subscriptions...

This is perhaps the only animation on fast and slow block to polyspermy available in youtube!

whenever I comeacross a mcq on conception i come back to this video

Jajakallah khairan(Allah gives u best reaward ) for this excilent vedio.

what a helpful explanation 😄😄 !! Thanks a lot

awesome and straight to the point well done! :D

You deserve a Nobel!

Excellent video! Thank you very much.

Great video. Wish there was more on Acrosomal reaction though. Great work anyways!

u just made me more easily understandable this topic....thnx thnx alot😇😇😇😇nice explanation

Excellent explanation,👏

Best explanation for fertilisation thx

I would have liked to see a more detailed explanation of the acrosome reaction, but great video.

I don't think he second polar body should be there on the picture before fertilization and completion of Meiosis II, right?

Nice video!!!

The wave of Ca2+ release causing slow blocking is due to the spermatozoon that has entered the oocyte membrane or is that by the oocyte itself?

Really interesting easy to understand

perfect!

Great video

excellent

Nice animation

Thankyou for thiss.

Please I'm confused is it zona pellucida first or corona radiata And please what enzymes dissolves each

Is the egg completes meiosis II before fertilizes or after?

Very helpful

Está en inglés, y aún así le entendí a la perfección. Gracias!

Informative

Best explained video dear😊😊😊☺

Awesome

✨ awesome

Great👏

Imagine naming your child "Zygote"

Exactly how much time each stage of fertilization takes?

Good

helpful

Thnkuuuu💕💕

Good👍

What are the sperm lysine produced by human reptiles and amphibian?

I thought it is MEIOSIS II not MIOSIS at 3:15 ??

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Anderson me trouxe aqui

- fast block to polyspermy (depolarization) is not yet identified in mammal, isn't it? - is ZP3 found in human? I've heard it's found only in mouse. By the way, your video is really helpful

hmm so meiosis 2 never finishes until the sperm enters the ovum? so the ovum is still stuck in Metaphase 2?

Meiosis II not miosis

👏👏👏👏👏👏👏

In my book it's given ZP2???!!! Which is correct

How can I obtain a download of this?

Will the fertilization membrane still form if only one single sperm is injected with ICSI technique?? Thank youuu

I thought it was ZP2, not ZP3, that sperm cells bind to and that is cleaved by ovastacin!

The presentation is nice . but there are so many points are missing .sir, you should mention the enzymes and the different process e.g. dissolution of vitelline membrane etc.

zp3

Great video but the fly sound irretated me made me stop the video couple times😂

AP Biology

🇮🇳🇮🇳🇮🇳👏👏👏👏👏

FOETUS PROTECTED BY THREE VEILS OF DARKNESS "He makes you, In the wombs of your mothers, In stages, one after another, In three veils of darkness." [Al-Qur’aan 39:6] According to Prof. Keith Moore these three veils of darkness in the Qur’aan refer to: (i) anterior abdominal wall of the mother (ii) the uterine wall (iii) the amnio-chorionic membrane. EMBRYONIC STAGES "Man We did create From a quintessence (of clay); Then We placed him As (a drop of) sperm In a place of rest, firmly fixed; Then We made the sperm Into a clot of congealed blood; Then of that clot We made A (foetus) lump; then We Made out of that lump Bones and clothed the bones With flesh; then We developed Out of it another creature. So blessed be Allah, The Best to create!" [Al-Qur’aan 23:12-14] In this verse Allah states that man is created from a small quantity of liquid which is placed in a place of rest, firmly fixed (well established or lodged) for which the Arabic word qarârin makîn is used. The uterus is well protected from the posterior by the spinal column supported firmly by the back muscles. The embryo is further protected by the amniotic sac containing the amniotic fluid. Thus the foetus has a well protected dwelling place. This small quantity of fluid is made into alaqah, meaning something which clings. It also means a leech-like substance. Both descriptions are scientifically acceptable as in the very early stages the foetus clings to the wall and also appears to resemble the leech in shape. It also behaves like a leech (blood sucker) and acquires its blood supply from the mother through the placenta. The third meaning of the word alaqah is a blood clot. During this alaqah stage, which spans the third and fourth week of pregnancy, the blood clots within closed vessels. Hence the embryo acquires the appearance of a blood clot in addition to acquiring the appearance of a leech. In 1677, Hamm and Leeuwenhoek were the first scientists to observe human sperm cells (spermatozoa) using a microscope. They thought that a sperm cell contained a miniature human being which grew in the uterus to form a newborn. This was known as the perforation theory. When scientists discovered that the ovum was bigger than the sperm, it was thought by De Graf and others that the foetus existed in a miniature form in the ovum. Later, in the 18th century Maupertuis propagated the theory of biparental inheritance. The alaqah is transformed into mudghah which means ‘something that is chewed (having teeth marks)’ and also something that is tacky and small which can be put in the mouth like gum. Both these explanations are scientifically correct. Prof. Keith Moore took a piece of plaster seal and made it into the size and shape of the early stage of foetus and chewed it between the teeth to make it into a ‘Mudgha’. He compared this with the photographs of the early stage of foetus. The teeth marks resembled the ‘somites’ which is the early formation of the spinal column. This mudghah is transformed into bones (izâm). The bones are clothed with intact flesh or muscles (lahm). Then Allah makes it into another creature. Prof. Marshall Johnson is one of the leading scientists in US, and is the head of the Department of Anatomy and Director of the Daniel Institute at the Thomas Jefferson University in Philadelphia in US. He was asked to comment on the verses of the Qur’aan dealing with embryology. He said that the verses of the Qur’aan describing the embryological stages cannot be a coincidence. He said it was probable that Muhammad (pbuh) had a powerful microscope. On being reminded that the Qur’aan was revealed 1400 years ago, and microscopes were invented centuries after the time of Prophet Muhammad (pbuh), Prof. Johnson laughed and admitted that the first microscope invented could not magnify more than 10 times and could not show a clear picture. Later he said: "I see nothing here in conflict with the concept that Divine intervention was involved when Muhammad (pbuh) recited the Qur’aan." According to Dr. Keith Moore, the modern classification of embryonic development stages which is adopted throughout the world, is not easily comprehensible, since it identifies stages on a numerical basis i.e. stage I, stage II, etc. The divisions revealed in the Qur’aan are based on distinct and easily identifiable forms or shapes, which the embryo passes through. These are based on different phases of prenatal development and provide elegant scientific descriptions that are comprehensible and practical. Similar embryological stages of human development have been described in the following verses: "Was he not a drop Of sperm emitted (In lowly form)? Then did he become a clinging clot; Then did (Allah) make and fashion (him) In due proportion. And of him He made Two sexes, male and female." [Al-Qur’aan 75:37-39] "Him Who created thee, fashioned thee in due proportion, And gave thee a just bias; In whatever Form He wills, Does He put thee together." [Al-Qur’aan 82:7-8] EMBRYO PARTLY FORMED AND PARTLY UNFORMED At the mugdhah stage, if an incision is made in the embryo and the internal organ is dissected, it will be seen that most of them are formed while the others are not yet completely formed. According to Prof. Johnson, if we describe the embryo as a complete creation, then we are only describing that part which is already created. If we describe it as an incomplete creation, then we are only describing that part which is not yet created. So, is it a complete creation or an incomplete creation? There is no better description of this stage of embryogenesis than the Qur’aanic description, "partly formed and partly unformed", as in the following verse: "We created you Out of dust, then out of Sperm, then out of a leech-like Clot, then out of a morsel Of flesh, partly formed And partly unformed." [Al-Qur’aan 22:5] Scientifically we know that at this early stage of development there are some cells which are differentiated and there are some cells that are undifferentiated - some organs are formed and yet others unformed. SENSE OF HEARING AND SIGHT The first sense to develop in a developing human embryo is hearing. The foetus can hear sounds after the 24th week. Subsequently, the sense of sight is developed and by the 28th week, the retina becomes sensitive to light. Consider the following Qur’aanic verses related to the development of the senses in the embryo: "And He gave You (the faculties of) hearing and sight and feeling (And understanding)." [Al-Qur’aan 32:9] "Verily We created Man from a drop Of mingled sperm, In order to try him: So We gave him (the gifts), Of Hearing and Sight." [Al-Qur’aan 76:2] "It is He Who has created For you (the faculties of) Hearing, sight, feeling And understanding: little thanks It is ye give!" [Al-Qur’aan 23:78] In all these verses the sense of hearing is mentioned before that of sight. Thus the Qur’aanic description matches with the discoveries in modern embryology.

These sperms are really energetic😋

So many errors in this ...

Human creation in Quran وَلَقَدۡ خَلَقۡنَا ٱلۡإِنسَٰنَ مِن سُلَٰلَةٖ مِّن طِينٖ We have created man from an extract of clay. (Surah Al-Mu'minun, verse 12) ثُمَّ جَعَلۡنَٰهُ نُطۡفَةٗ فِي قَرَارٖ مَّكِينٖ Then We made him a sperm-drop in a firm resting place. (Surah Al-Mu'minun, verse 13) ثُمَّ خَلَقۡنَا ٱلنُّطۡفَةَ عَلَقَةٗ فَخَلَقۡنَا ٱلۡعَلَقَةَ مُضۡغَةٗ فَخَلَقۡنَا ٱلۡمُضۡغَةَ عِظَٰمٗا فَكَسَوۡنَا ٱلۡعِظَٰمَ لَحۡمٗا ثُمَّ أَنشَأۡنَٰهُ خَلۡقًا ءَاخَرَۚ فَتَبَارَكَ ٱللَّهُ أَحۡسَنُ ٱلۡخَٰلِقِينَ Then We turned the sperm-drop into a clot, then We turned the clot into a fetus-lump, then We turned the fetus-lump into bones and We clothed the bones with flesh; thereafter We developed it into another creature. So glorious is Allah, the Best of the creators. (Surah Al-Mu'minun, verse 14)