Glanzmann Thrombasthenia (GT) - Platelet Disorders - Hemostasis - Hematology Series

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Glanzmann Thrombasthenia (GT) is an autosomal recessive defect in the GPIIb/IIIa (GP2b/3a) receptor on the platelet which leads to defective platelet aggregation.
Bernard-Soulier Syndrome (BSS) is an autosomal recessive (AR) disorder characterized by a defective GP1b platelet receptor leading to a problematic platelet adhesion process (primary hemostasis).
Ristocetin Cofactor Assay (RIPA) is usually abnormal in cases of Bernard-Soulier Syndrome (BSS).
Bleeding time is prolonged, platelets are big in size, but few in number (Macrothrombocytopenia).
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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding 🩸 time (BT) is another test for platelet function.
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18 сен 2024

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Комментарии : 64

@MedicosisPerfectionalis 4 года назад

Use the Promo Code: 35OFFCANCER to get a 35% discount on any product on my website (only 18 left). 💊 Get my Anti-Cancer Pharmacology Course: www.medicosisperfectionalis.com/products/courses/pharmacology/anticancer/

@Mutelli0 2 года назад

i sadly have the glanzmann plt disorder and im 16 so i really wanna learn more about it myself then just hear it from doctors who wont go in deeper details , this helped alot tysm

@PatriciaSantos-qy9dl 4 года назад

i am currently studying hemathology and ive been watching videos the whole day since you didnt have this topic, now at the end of the day you gave me this sense of satisfaction i couldnt be any more thankful

@MedicosisPerfectionalis 4 года назад

Wow 🤩 You’re amazing, Patricia 👍👍

@manarsmaan2624 2 года назад

You deserve to have a million subscribers. When I pass my Ascp board I will write about you on my Facebook page and my Instagram just to thank you for this amazing youtube channel you have and I already told my college friends and people who worked with me in the hospital about you . My Respect

@MedicosisPerfectionalis 2 года назад

Thank you 😊 This means a lot to me!

@ghaziaraheem4177 Год назад

Repetition is the key, thank you so much for saying it over and over again!

@akshayakedar6643 3 года назад

Your way of teaching is just freaking awesome... Love this video.. !!

@MedicosisPerfectionalis 3 года назад

Thank you so much 😊

@clonitheclone2089 4 года назад

Thank you for the explanation. I am currently studying clinical pathology in medical school, and your videos have been helping me a lot in understanding and memorizing (also during biochem previous block when we studied about hematology)! 😊

@MedicosisPerfectionalis 4 года назад

Awesome 👏 I am so happy to hear that! Thank you so much for putting a smile on my face:)

@fatmaabdokhalifa8392 Год назад

Please, can you start the general surgery playlist 🙏🏾🙏🏾... You are a talented one sir

@MedicosisPerfectionalis Год назад

Thank you! I have a Surgery HighYields course on my website (including General Surgery): www.medicosisperfectionalis.com/

@abbyn8179 2 года назад

Thanks for this video! I have Glanzmanns and wanted to have a better understanding 😊

@dusty_wings 4 года назад

Still loving your videos ^^ been actually learning alot lately. Have you done a video on bronchitis? Would be nice to learn more about the infection.. All the best // dusty :3

@MedicosisPerfectionalis 4 года назад

Yes! I have a video about chronic bronchitis in my Pulmonology playlist.

@dusty_wings 4 года назад

@@MedicosisPerfectionalis ah cool ^^ been wondering about asking lol i have a past with the infection to do with my family ^~^ it's over but i can always learn incase it's genetic...

@MedicosisPerfectionalis 4 года назад

Learning is good! I am so sorry to hear that...I hope you’re fine today.

@elaineluther1799 4 года назад

Hi Medicosis Perfectionalis: Your videos are great; I'm trying to watch ALL of them. You have answered many long-standing questions that no one else ever explained, and it is quite a relief. However, there is one thing in your PLT videos that keeps bugging me. You say that a defect in primary hemostasis makes patient subject to severe intracranial bleeding, but NOT subject to cranial bleeds. Excuse my ignorance, what is the difference between an intra-cranial bleed and a cranial bleed?

@MedicosisPerfectionalis 4 года назад

Hey 👋 Elaine....Thank you so much for watching my videos...I really appreciate it. There is no difference between cranial and intracranial bleeding. Intracranial bleeding can happen in primary hemostasis defect (only in severe cases of primary hemostasis defects). Intracranial bleeding is more common in secondary hemostasis defects though. Hope it helps!

@dennisgarber 4 года назад

I am never comfortable accepting gifts from virologists.

@MedicosisPerfectionalis 4 года назад

I am afraid I don’t understand

@dusty_wings 4 года назад

@@MedicosisPerfectionalis it's a joke about how you have knowledge on viruses and infections... Mr. Garber doesn't wanna catch anything from you sending an infection 😅 if you understand what i mean

@MedicosisPerfectionalis 4 года назад

Haha 😂 Sorry! Now, I get it!

@Cardio5752 4 года назад

That's amazing Thank you ❤👌

@MedicosisPerfectionalis 4 года назад

My pleasure 😇

@dusty_wings 4 года назад

Me and my friend sat here trying to pronounce the title before we hear you say it is kinda fun x)

@MedicosisPerfectionalis 4 года назад

Haha 😂 I adore this friendship that's based on science 😊😊

@dusty_wings 4 года назад

@@MedicosisPerfectionalis literally half the time we spend together i bring up your channel and just start brainstorming when we smoke x) it's great... I just need a home and not a hostel haha

@hannahrosa5485 4 года назад

Thank you once again. Glad I learned my freaking alphabet. Still, much of this went over my head. Easily done. But always fun.

@MedicosisPerfectionalis 4 года назад

Haha 😂 Thank you so much 😊

@basictobougie3343 2 года назад

this was awesome....thanks man.

@MedicosisPerfectionalis 2 года назад

My pleasure 😇

@amanitahir2490 Год назад

Thank you so much medicosis, I just have a question: Why are platelet giant in Bss wheras they are normal size in GT ?

@MedicosisPerfectionalis Год назад

My pleasure! I don’t have an answer to that question!

@farahkhan7718 4 года назад

U are awesome👍... Can't appreciate for ur efforts...

@MedicosisPerfectionalis 4 года назад

It’s my pleasure 😇

@farahkhan7718 4 года назад

@@MedicosisPerfectionalis 😊😊😊 I wanted to ask you for a favor, if u have time then plz make videos on biochem topics.... I'm a little weak in biochem🥴.... I have to prepare for my mid exams...

@MedicosisPerfectionalis 4 года назад

Ok 👍

@farahkhan7718 4 года назад

@@MedicosisPerfectionalis thank u so much ❤️.... May Allah bless you with more subcribers🙏😇

@edriellebon2517 Год назад

You are the best!

@MedicosisPerfectionalis Год назад

Thank you 😊

@yassermahmoud4366 Год назад

How can recover

@moin415 3 года назад

Hello , my son 2years old has GT. Any treatment? I am from Indian

@oliviamettler30 2 года назад

Why is the platelet count normal in Glanzmann's but increased in BSS?

@yannychiou282 Год назад

decreased* because in Glanzmann, there's a normal num of PLTs but the issue is that these PLTs have a problem with their FUNCTION (so number does not have a problem) and for BSS, function and number are both decreased

@alshareeff8 2 года назад

You are the best

@MedicosisPerfectionalis 2 года назад

Thank you 😊

@ijj0777 3 года назад

فخامه يا برنس

@MedicosisPerfectionalis 3 года назад

Thank you 🙏

@mehmetfatihtutar9062 3 года назад

Have thrombasthenia treatment of Glanz man is said to be turkey. I can't speak and understand English so I don't understand the video. I am writing with google translation, please reply

@MedicosisPerfectionalis 3 года назад

I don’t understand

@mehmetfatihtutar9062 3 года назад

@@MedicosisPerfectionalis Is there a treatment for this disease

@mehmetfatihtutar9062 3 года назад

@@MedicosisPerfectionalis ???

@mehmetfatihtutar9062 3 года назад

@@MedicosisPerfectionalis Is there any treatment?