Grignard Reagent, Reaction, Mechanism and Shortcut

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Leah4sci.com/grignard presents: Grignard Reagent, Reaction, Mechanism and Shortcut
📺Watch Next: Organometallic Reagents and Reactions • Organometallic Reagent...
Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: leah4sci.com/orgo-ebook/
Grignard reagents are my go-to for chain elongation in orgo 2. This video focuses on the formation of the highly reactive organometallic: The Grignard reagent, including formation, reactivity, and its use in synthesis reactions. You’ll learn how to form a Grignard, the step by step mechanism, as well as a shortcut for predicting Grignard reactants and products.
Links & Resources Mentioned In This Video:
Polar Protic and Aprotic Solvent Video: • Polar Protic, Aprotic,...
Find even more on Grignard reagents including the Common Grignard Reactions cheat sheet on my website: leah4sci.com/grignard
In this video:
[0:30] Overview of Grignard Reaction
[2:39] Purpose for Using Aprotic Solvent
[4:43] Grignard Reaction Mechanism
[7:39] Grignard Reaction Shortcut
[8:16] How to Determine Grignard Reactant
Follow along with your semester by using my Orgo Syllabus Companion: leah4sci.com/syllabus
For more in-depth review including practice problems and explanations, come join my online membership site the organic chemistry study hall: leah4sci.com/join
For private online tutoring visit my website: leah4sci.com/organic-chemistry
For questions and comments, find me on social media here:
Facebook: / leah4sci
Twitter: / leah4sci
Instagram: / leah4sci
Pinterest: / leah4sci

Опубликовано:

17 фев 2020

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Комментарии : 169

@kara-me4co 4 года назад

our class loves you. you helped all of us pass science and for that we owe you. thank you for all your sci help! you’re awesome leah!!!!

@Leah4sci 4 года назад

That's amazing to hear Kara! so honored to be able to help you and your classmates

@danmadefurniture 3 года назад

thanks leah! absolutely love your videos. you go far more in depth than my orgo chem lecturers and your videos are the reason i'm doing so well in organic chem.

@Leah4sci 3 года назад

You're so welcome! I'm happy to hear how much my resources are helping you!

@shantaebennett7888 3 года назад

I just want to thank you so much because I’ve been struggling so much with o-chem and so far I have understood everything that you have went over. I truly want to thank you for these videos and tips!!!

@Leah4sci 3 года назад

You're very welcome! So glad it helped you!

@sydniemaltz8558 3 года назад

Amazing!! This video was extremely helpful. You basically took most of one lecture, put it into a few minutes, and made it very easy to understand. Your videos have helped me a ton with o chem. You are really talented at teaching and creating videos! Thank you so much!!

@Leah4sci 3 года назад

You're very welcome!

@SkySky-wk9vv 4 года назад

You’re amazing!!!!’ I really appreciate your videos, thank you for sharing this for free. Very helpful!!!!! God bless you, thank you for helping us with organic, you’re the best!!!!!!

@Leah4sci 4 года назад

Thank you for the kind words and you are very welcome!

@robertchambezi8590 2 месяца назад

Leah I love how you build your explanations from bottom up starting with basics. Much love ❤

@Leah4sci 2 месяца назад

You're so welcome!

@y.a.46 2 года назад

The end part of the video is what makes this better than any other videos I have seen. I was always uncomfortable with come up with reagents given final product questions but not anymore thanks to you.

@Leah4sci 2 года назад

Yay! So happy t help you understand!

@sinajafarzadeh9577 2 года назад

wow! you made it so easy!! I love how you cut the chase and just explain the main idea of each topic. I think many college classrooms get boring and unproductive because profs go on tangent and students do not have that long of attention spans to follow it.

@Leah4sci 2 года назад

Glad it was helpful, and I agree that there are some professors out there like that. Happy to provide a quick, to-the-point tutorial to help!

@diegoorellana7322 Год назад

This is THE best video on the topic I’ve ever seen so easy to follow and easy to understand

@Leah4sci Год назад

Wow, glad you liked the video! Thanks for watching.

@trudatbellyfat7358 4 года назад

I actually took orgo 2 years ago and passed with flying colors thanks to you and your videos. I still watch them because I honestly just enjoy them. They're extremely clear and concise, but still thorough. Plus, your voice is very relaxing. 👍😊

@Leah4sci 4 года назад

Oh wow, thank you, and congratulations on acing orgo!! :)

@ahmadabdullah8168 4 года назад

Your videos are superduper fantastic.When I started my organic course I thought it's a monster... but with your videos I've friend with orgo pall.... Thanks very much,leah!!! Keep up the good work! Teachers like you truly are a blessing... 👌👍❤

@Leah4sci 4 года назад

Awww, thanks so much!

@tyephan7475 4 года назад

Your explanations are so clear and helpful!! Thank you for all your hard work :)))

@Leah4sci 4 года назад

You're very welcome!

@jockgomes5629 3 года назад

Your class was amazing, thank you so much!!!

@Leah4sci 3 года назад

You're so welcome!

@andrescontreras4864 Год назад

Great job! I love how you use examples and explain everything step by step, greetings from Mexico :D

@Leah4sci Год назад

Thank you! I appreciate the kind words! :)

@AFRICANDIVA Год назад

Wow! This was the easiest way I’ve ever seen this reaction done. Love it!🎉

@Leah4sci Год назад

Thank you! Glad to help. Make sure to check out my full Grignard tutorial at Leah4sci.com/Grignard

@aleena3977 Месяц назад

thank you, this is so helpful and concise!

@Leah4sci Месяц назад

You're welcome, glad it was helpful!

@sarahsherlock1870 2 года назад

You just saved me. This is the only video that has actual helped me visualise it

@Leah4sci 2 года назад

So happy to help you understand!

@kennixcheung2270 2 года назад

Hi Leah thanks for all yours amazing videos. They helped me got an A on my both org chem courses. Now I am using them again for my MCAT preparation. Thank you so much!!!

@Leah4sci Год назад

You're very welcome! Make sure to check out my MCAT videos, too: leah4sci.com/MCATyoutube

@yashgupta5143 4 года назад

You made my weakest subject quite strong thank you so much for that!!!! I want to ask you can you make a video on reimer tiemann reactions plzz

@Leah4sci 4 года назад

Awesome, so glad I helped! As for the video request, the free videos are what I do as I have time. For more help with this topic, feel free to contact me through my website: leah4sci.com/contact

@tirthjyotikar8162 3 года назад

Very Nice Example Perfect Way Of Introducing To Something You Made Us Understand A Tough Topic With Ease Thank You Very Much Loved The Video

@Leah4sci 3 года назад

You are very welcome! I'm glad it helped!

@tramnguyen4488 4 года назад

Such a great video ! Thanks Ma'am

@Leah4sci 4 года назад

You're welcome!

@ridhhingrover4845 3 года назад

Great teaching!

@Leah4sci 3 года назад

Glad it was helpful!

@dharshinis3740 3 года назад

Thank you so much🥺❤️....you are seriously great....thanks to you tube for recommending me this video....I was searching for a good explanation like this❤️❤️

@Leah4sci 3 года назад

Glad I could help, you're so welcome!

@dharshinis3740 3 года назад

@@Leah4sci lots of love from India Mam❤️❤️

@halidsufiyan3663 2 года назад

You are the best organic chemistey teacher from 🇪🇹🇪🇹🇪🇹🇪🇹🇪🇹🇪🇹🇪🇹

@Leah4sci 2 года назад

Thanks so much!

@sarahholland5980 3 года назад

you're amazing! thank you for going through the basics and how the electrons are flowing. it makes the reactions so much easier to understand but professors just start drawing arrows without explanations

@Leah4sci 3 года назад

You're very welcome! I'm glad it helped!

@praneethlokini6557 4 года назад

Thank you so much Mam ! Your videos are helping me very effectively to prepare for my competitve exams! Thank you .

@Leah4sci 4 года назад

You're very welcome!

@abdullahe3674 3 года назад

Bless you Prof!!!

@Leah4sci 3 года назад

Thank you!

@OmniaElbatrawy 3 года назад

You are amazing, thank you so much 🤩🌻🌻

@Leah4sci 3 года назад

You’re welcome 😊

@SHERY_T 4 года назад

I love you and your technique of teaching

@Leah4sci 4 года назад

Thank you! 😊

@srianitha3142 3 года назад

Thanks a lot . It helps me to understand organic chemistry better. Learning organic chemistry is easy with you. Thanks a lot.

@Leah4sci 3 года назад

You are very welcome!

@hanaanasr1064 3 года назад

Hi can i talk with u? @Sri Anitha

@kunalshaw2975 4 года назад

i am jee aspirant .you helped me to clear some of my weakest concept.

@Leah4sci 4 года назад

So glad it helped you!

@farrukhhussain1846 2 года назад

very good lecture

@Leah4sci 2 года назад

Glad you like it!

@manojmaheshwari4055 4 года назад

You just made my day ✌🏻

@Leah4sci 4 года назад

Awesome!

@chachap59 2 года назад

Thank you so much 😊

@Leah4sci 2 года назад

You're welcome 😊

@marija5196 2 года назад

You are amazing, thank you so much 😍

@Leah4sci 2 года назад

Awww, you're very welcome!

@niloofarkh4779 2 года назад

THANK U SO MUCH

@Leah4sci 2 года назад

You're so welcome!

@anirudhraj775 4 года назад

Your videos are very helpful for my cbse board exams... Love from India

@Leah4sci 4 года назад

Thank you, glad to help. Wishing you the absolute best on your boards

@spectroxis6418 2 года назад

Thanks again leah, your videos have come in clutch now like uhh 100+ times? :)

@Leah4sci 2 года назад

Nice!!! Glad to help you understand!

@jiyahaq1675 4 года назад

I found long ago a perfect teacher,

@Leah4sci 4 года назад

@Vivek-Goel_Superfan 2 месяца назад

"Same thing happens for alcohol @4:15" was so jarring right after your ice-cream analogy 🤣💀It may have been unintentional, but it was a great way to reel back deep attention midway through the video! Thank you!

@Leah4sci 2 месяца назад

Woohoo, it wasn't intentional but I'm glad it reeled you back in!

@haneenhammad8562 2 года назад

thank you lifesaver!!!❤

@Leah4sci 2 года назад

You're welcome!

@ribidimi 2 года назад

you have the nost helpful videos

@Leah4sci 2 года назад

Glad you like them!

@saygeek3753 4 года назад

Ma'am please upload a video series on Carbonyl Chemistry and short tricks to solve it's reaction mechanism.

@Leah4sci 4 года назад

I have some carbonyl reaction videos posted already. I cover these in even more depth in the orgo study hall leah4sci.com/join (ketones, aldehydes, carboxylic acids / derivatives, protecting groups...)

@marvinsteinwinter84 22 дня назад

Strong Video, Im German and I understood everything

@Leah4sci 19 дней назад

Awesome! So happy to help!

@dr.krushnakumarjilariya8940 4 года назад

Nice explanation madam

@Leah4sci 4 года назад

Thank you so much 🙂

@chemrev3678 4 года назад

Hey Leah, I have been trying to years to get organic chemistry but its only upon coming across your videos that things are finally starting to click. Thank you for your work! What books would you suggest that follow your way of explaining things?

@Leah4sci 3 года назад

Sorry for the late reply! I'm glad to hear you are understanding! Here are some of my recommendations for orgo resources: leah4sci.com/5-must-have-organic-chemistry-resources/

@SHERY_T 4 года назад

You are great

@Leah4sci 4 года назад

Awww, thanks!

@michaelokonkwo5126 2 года назад

Chaii. U are wonderful. I love u. God bless you. I pray I meet u one day.

@Leah4sci 2 года назад

Thanks so much!

@siddhantsingh5962 4 года назад

Please make a video on different types of Tautomerisms

@Leah4sci 3 года назад

I do have a video on the reaction and mechanism of keto enol tautomerism in both acid and base. Read the article and find the video at leah4sci.com/keto-enol-tautomerization.

@Ajayd04 4 года назад

Nice love from India

@Leah4sci 4 года назад

Thank you

@aryanhossain211 2 года назад

Ma'am can you make a video on all the reaction mechanisms of organic chemistry of international advanced level(IAL A2) chem? It would be very helpful for me as my tutors don't show me the reaction mechanisms of most of the reactions and so I seek help from youtube. I found your channel in 2021 and from then onwards, my knowledge is improving 😀😀. Can you make a video of the reaction mechanisms? Thank you ❤️.

@Leah4sci 2 года назад

That would be a very long RU-vid video to contain every mechanism studied in undergraduate Orgo. For help with questions like this, as well as full-length mechanisms and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/

@SohelRana-vw6xt 3 года назад

Awesome

@Leah4sci 3 года назад

Glad you like it!

@rajanmishra7733 4 года назад

Please upload summary of all important organic reaction .

@Leah4sci 4 года назад

By all you mean every single chapter or all grignard reactions?

@rajanmishra7733 4 года назад

@@Leah4sci yes please

@nishanthvs3063 4 года назад

As you can.

@estherlee8694 4 года назад

very helpful, thank you! But can you explain how we know the carbonyl group at the very end is an aldehyde, rather than a ketone? How do we know there is an H present instead of an R group?

@SeanOchiagha 4 года назад

Because OH is attached to a secondary carbon

@Leah4sci 4 года назад

Watch my functional groups video to learn the specifics leah4sci.com/organic-chemistry-functional-groups-simplified-to-memorize/

@mindfullness7607 4 года назад

Mam please upload more videos this is request ,we need more topics to cover our syllabus

@Leah4sci 4 года назад

You can find my full list of resources here: leah4sci.com/ultimate

@akashyadav-dm4zq 4 года назад

Ma'am please upload a videos on retrosynthetic analysis

@Leah4sci 4 года назад

Thanks for the suggestion

@aabidhussain428 8 месяцев назад

Nice😊

@Leah4sci 8 месяцев назад

thanks

@aabidhussain428 8 месяцев назад

@@Leah4sci good to see your comment

@eman4159 2 месяца назад

Did explain it when using excess of Grignard to alcohol and it gives esters instead of ketone or aldehyde

@Leah4sci 2 месяца назад

I hope you found what you were looking for in this video! If you haven't already, make sure to view my tutorial and cheat sheet at Leah4sci.com/Grignard. For further questions, you can contact me through my website at Leah4sci.com/contact

@sarak. 3 года назад

I was wondering in the very last example of finding out the reactants. I thought gringard agent is added only to elongate the chain without Mg attaching itself to the carbonyl carbon. Can the reactant be cyclohexanone? If you followed the steps of the shortcut you’d get the same product ?

@Leah4sci 2 года назад

Cyclohexanone would not work for this example because we want the position of the final alcohol to be on the carbon that is one removed from the ring. We don't want the alcohol directly bonded to the ring. For help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/

@mindfullness7607 4 года назад

Mam we need naming reaction like benzillic acid rearrangement and all types of name reaction with mechanism

@Leah4sci 4 года назад

Use my syllabus guide to match up my resources to what you are studying: leah4sci.com/syllabus

@BrainBlitzAudios 4 года назад

This video is very helpful for beginners, excellent content. Surely it will motivate others to follow. I #BrainBlitzAudios appreciate it.😊😊😊💞💛💛💚💚💜💜💞

@Leah4sci 4 года назад

Glad it was helpful!

@_galx 3 года назад

"... pronounced Grignard, not Grig-nard" you caught me 😂😭😭

@Leah4sci 3 года назад

@samriddhadas9316 23 дня назад

hey ! we have conversions in organic chemistry. like we are given the reactant and the product and we are supposed to convert the reactant into the product anyhow. thing is that i have learnt the individual reactions but still can not effectively do conversions. can you please suggest what should i do to do them effectively?

@samriddhadas9316 23 дня назад

for example we were given to convert ethanol to but-2-yne . i was able to convert it into but-1-yne but could not convert it into but-2-yne. i dont understand how to bring the triple bond to the 2nd carbon.

@samriddhadas9316 23 дня назад

also , can H2 + Ni be used to convert alkenes to alkynes?

@it27shabiabbas12 3 года назад

I'm from india can u please make a video on hardest question practise on organic chemistry like haloalkane , alcohals , etc

@Leah4sci 11 месяцев назад

Thanks for the recommendation. I post free videos as I have time and am always looking for suggestions.

@Rodsmphepo-yaomba 3 года назад

Please help 1. A compound A reacts with an alkylmagnesium halide B to give the final product C, of formula C5H12O. Dehydration of C gives a compound D which on oxidation gives two products E and F. The later reacts with 2, 4 - DNPH but E does not. However, E turns blue litmus paper red. Compound D decolourises bromine dissolved in carbon tetrachloride. a. Write structures A and B. b. Using appropriate structures, write the sequence of reactions to the final products, E and F. c. Name the compounds A, C, D and F, d. Draw all the possible stereoisomers for each of the optically active compounds in c above.

@Leah4sci 2 года назад

I'm sorry, but I don't offer tutoring over social media. For help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/

@salad6369 3 года назад

At 8.33, y do we need break either side when carbon has only 3 bonds in the first place?Y can't we just add on another bond n let it be sp3 hybridised?

@Leah4sci 3 года назад

Thanks for watching and asking! First, the carbon bound to the alcohol group has 4 bonds to begin with. The rules for drawing bond-line structures tell us a hydrogen is also bound to that carbon in addition to the oxygen and other carbon groups. Second, the reason we are breaking a bond in this example is because we are working backwards to predict the reactants. A Grignard reaction is important for its ability to elongate carbon chains by the formation of new carbon-carbon bonds. To work backwards in a Grignard reaction, we must think about breaking bonds rather than forming them.

@eslamhassan6470 4 года назад

I'm from Egypt l want your videos with translation into Arabic if you can do ......you are very good ...you're fantastic

@Leah4sci 4 года назад

I'm so glad you like the videos, unfortunately I'm not able at this time to have them translated.

@eslamhassan6470 4 года назад

@@Leah4sciok thank you very much

@jamilabonyadi3171 3 года назад

what happens to the Mg and I? last reaction

@Leah4sci 3 года назад

Thanks for asking! After the reaction, the magnesium and iodine from the Grignard reagent remain in solution as a positively charged Mg-I unit. It is common to ignore the Mg-I on paper because it is not a part of the primary organic product.

@jamilabonyadi3171 3 года назад

@@Leah4sci thank you!

@shikhaalyafie 3 года назад

i find your videos harder to comprehend in all honesty

@Leah4sci 3 года назад

I'm sorry to hear that! I hope you're able to find another resource that works for you!

@ttyyhyyhy3815 3 года назад

Miss can you make online classes on organic chemistry using google meet

@Leah4sci 3 года назад

I can't do that, but I do have office hours as part of my Study Hall. leah4sci.com/join

@ttyyhyyhy3815 3 года назад

@@Leah4sci but it is not free

@ginar3398 3 года назад

Grignard reagents are my 13th reason why

@Leah4sci 2 года назад

@bytheway1031 2 года назад

🎂Victor Grignard 05-06-2022

@Leah4sci 2 года назад

Man, I missed his birthday party! lol

@shakthianistonshakthi6918 3 года назад

Mam u sound like Scarlett johanson

@shakthianistonshakthi6918 3 года назад

In this video it’s much more apparent. God bless you.

@Leah4sci 3 года назад

I'll take that as a compliment, thanks!

@hanaanasr1064 3 года назад

Hey, iam Egyptian so i speak Arabic, i try to understand you and then i understand 60% because of language. Can you help me if you wrote explanation and send me it?? ❤️❤️

@Leah4sci 3 года назад

Making the videos is what I do in my spare time, so I don't have time to send you a written explanation. However, you can turn on closed captioning and slow the speed down to help you understand better. Thanks for watching!