Guillain-Barré Syndrome - CRASH! Medical Review Series 

Thank you - Cartoons and visual images help so much in remembering all the diseases!

Always watching your lectures, very informative and clear. Thank you very much Dr. Bolin!

Neurology: Guillain-Barre Syndorme (GBS [By MD Paul W. Bolin]), a Idiopathic, demyelinating, autoimmune/inflammatory, symmetrical ascending polyneuropathy (Hell yeah, my type of Pathology); Status Post Camphylobacter Jejuni Infection et al; Rare Incidence (Epidemiology); 7% Mortality Rate (Good Prognosis otherwirse); SSx: 1) Sensory Deficits (Lower Extremity, the Feet), 2) Motor Deficits, 3) Autonomic Instability; 4) Myasthenia (Weakness), 5) Ataxia, 6) Bilateral Paresthesia, 7) Paralysis Progression; 8) Facial/Bulbar Upper Extremity Symptoms (Less Commmon); Physical Examination (Px) or Typical Clinical Presentation: 1) Weakness of Lower Extremities (Bilaterally), 2) Loss of Deep Tendon Reflexes (DTRs); Dx: 1) Basic/Routines Laboratories are Normal (CBC, CMP). 2) Lumbar Puncture (LP) with Cerebral Spinal Fluid (CSF)Analysis with Albuminocytologic Dissociation (Elevated Protein without Inflammatory Cells, A unique/diagnostic Finding). 3) Confirmatory Assay is an Electromyelogram (EMG) and/or Nerve Conduction Studies (Most Accurate Test). DDx: 1) Vitamin B12 Deficiency (LE/Feet Paresthesia) and CBC (Macrocytic Anemia and Low Vitamin Level); 2) Spinal Cord Injury (Traumatic or Vascular) gives Unilateral Symptomatology (CT/MRI Diagnosis), 3) Spinal Cord Compression (Tumor, etc) will also give Unilateral Manifestations rather than Bilateral (CT/MRI Diagnosis); 4) Nerve Root Compression is Localized to the Particular Nerve Affected (CT/MRI Investigation) , 5) Conversion Disorder, 6) West Nile Disease will give Constitutional Symptoms on Clinical Assessment and Laboratory Investigations, 7) Tick Paralysis (Rocky Mountain Spotted Fever [RMSF]) will have Constitutional Symptoms. 8 Poliomyelitis (Mostly Erradicated Pathology via Vaccination the US). Tx: 1) It is important to note Glucocorticoids (Steroids) are not effective for GBS or Contraindicated; 2) Admission To Hospital is Indicated for Observation (Vital Capacity Monitoring [15mg/kg Decrease shows Diaphragmatic Involvement or Below 1 Liter]) and Treatment; 3) Plasma Exchange is the initial Therapy; 4) Equally viable is Intravenous Immunoglobulin (IVIg). Cx: 1) Diaphragmatic Involvement merits Intensive Care Unit (ICU) Transfer for Intubation (Markedly in Respiratory Distress), 2) Hypotension is Fluid Responsive, 3) Cardiac Telemetry for Arrythmia, 4) DVT Prophylaxis due to Immobility with Enoxaparin, 5) Pain Management is Indicated with Carbamazapine, Gabapentin et al, 6) Neurology Consultation is Indicated. Post-Hospitalization: 1) Physical Therapy is Indicated, 2) 80-90 Recovery Rate (Rarely a Full Recovery), 3) Recovery Period varies, 4) Discharge Criteria is mindful of 1) Strenghth and 2) Stability. Goodness, this is a most unique autoimmune manifestation. My favorite Tenor has recently passed away due to GBS Syndrome and I had no idea how to go about! MD Paul Bolin, es immer geht gut wenn man kennst die Krankheit aber besser ist zu heilen Die Kranke. Prost!

Amazing! I am so thankful for sharing your expertise and knowledge. Thank you so much! 10/8/2018

Awesome lecture, Thank you!

Great video. Very informative. Thank you for sharing.

Thank you for sharing.

So what do you do if the HMO tried to hide their mistake and you have been living with this for over ten years?

Thank you 🙏🏽

thanks sir good video

Thank you

thank you

At least one slide for variant of GBS was necessary..

I had guillain barre syndrome 30 years ago and have still not recoved I was In icu for 3 months and another ward for 3 months. it has left me having to wear callipers when I walk.

I had GBS earlier this year and was hospitalized and am recovering from what seemed to be a mild case. I first noticed it in my hands, and then it traveled to my feet and legs. Just wanted to add that since he mentioned it usually started in the feet.

Good, thanks

🗣 that was great . .

Will massage help alleviate the pain? If so, how effective is it?

I had it almos three year ago and I still no recovered,I have a dropped foot my fingers are not responded like they told me they will, I have cramps all over my body and some days I’m so tired!

Hello Doctor 🙏 You said normal CBC test. What about ESR and CRP?

I got mine after two vaccines imediatly after finishing Hep C therapy using Pegysys. I was in a wheelchair for over 7 years and felt like I was wearing an iron maiden suite. I would force my self to walk as far as I could and 50 ft was my range before sitting on ground or floor. I disagree with your comments. It is how you get it or if you are treated as I was not.

How to treat this desease?.. any available medicine for this.

are Steriods usefull in CAIDP ( chronic )

Whats the difference between Guillaine Barre syndrome and Epstein Barr syndrome?

As a person with gbs I have a few things I disagree with !!

quand tu'ai en sénte c'est normale avec Sète maladie ou NN??