How do antidepressants work? - Neil R. Jeyasingam

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Dig into the discovery of antidepressant drugs, how they work, and what we still don’t know about depression.
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In the 1950s, the discovery of two new drugs sparked what would become a multi-billion dollar market for antidepressants. Neither drug was intended to treat depression at all- many doctors and scientists believed psychotherapy was the only approach to treatment. Neil R. Jeyasingam details the decades-long journey that followed and how it revolutionized our understanding of depression.
Lesson by Neil R. Jeyasingam, directed by Skirmanta Jakaitė, Art Shot.
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31 май 2024

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Комментарии : 3,7 тыс.

@VLJ23 3 года назад

i love learning about random stuff so i can tell my parents about random things in the middle of a conversation

@gabrielsalles8403 3 года назад

It increases the levels of serotonin and dopamine on there brains so if you ask them something it's more likely they will give you what you want

@nagarathnammats110 3 года назад

Same I like learning random stuff but I don't like learning math

@VLJ23 3 года назад

@@gabrielsalles8403 confusion? i dont tell them stuff to get what i want its just telling them random stuff i learn on RU-vid

@gabrielsalles8403 3 года назад

@@VLJ23 jk, I was just quiting my biology teacher, it's his excuse to teach us some random and unnecessary stuff

@VLJ23 3 года назад

@@gabrielsalles8403 ok

@fkmyoutube 3 года назад

"Asking for help isn't giving up, it's refusing to give up." - The Boy, the Mole, the Fox and the Horse -

@jewelsoftheworld101 3 года назад

Exactly..

@sakuranovaryan9261 3 года назад

Yeah giving up would be refusing to take help.. which I do unintentionally

@forregom 3 года назад

@MOHAMMAD EISA Bruh CRAUNCH!!d!!!ff!!

@LEO-zp5jw 3 года назад

I love that book! I'm glad someone finally mentioned it!

@aloyperez2059 3 года назад

@MOHAMMAD EISA troll

@DonnHowes 19 дней назад

I suffered severe depression 20 years ago as a teenage. Got diagnosed with ADHD. Spent my whole life fighting ADHD. Not until my wife recommended me to psilocybin mushrooms treatment. Psilocybin treatment saved my life honestly. 8 years totally clean. Never thought I would be saying this about mushrooms.

@Cate-sn2km 18 дней назад

Congrats on your recovery. Most persons never realizes psilocybin can be used as a miracle medication to save lives. Years back i wrote an entire essay about psychedelics. they saved you from death bud, lets be honest here.

@Paul_Michael 18 дней назад

Can you help me with the reliable source 🙏. I'm 56 and have suffered for years with addiction, anxiety and severe ptsd, I got my panic attacks under control myself years ago and they have come back with a vengeance, I'm constantly trying to take full breaths but can't get the full satisfying breath out, it's absolutely crippling me, i live in Australia. I don't know much about these mushrooms. Really need a reliable source!! Can't wait to get them

@SusanaGomez-mp8sk 18 дней назад

YES very sure of Dr.benfungi. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.

@Edennnn926 18 дней назад

100% agree I used to have Psychosis and paranoid thoughts like "people thinking about me talking about me etc. Very odd behavior after getting off Adderall from 7-16. Antidepressants at 18-29. 31 now. I took way to much, but took about 20g of Gold caps (Psilocybin containing mushroom) I analyzed my entire life. The emotions that came out helped me understand behavior etc more. Wont ever need to do it again because I'm happy and contempt forever, but I wish more people did this to alter their perception of reality. Would help with healing much trauma

@AlexanderMales-gh8bm 18 дней назад

How do I reach out to him? Is he on insta

@lilybird6868 2 года назад

Was in therapy for three years and have been taking antidepressants for about nine months since experiencing a breakdown early this year. If you're reading this and feel like you need medication, please talk to your doctor about it. It's made my life liveable again.

@MrGG-xc6sg Год назад

Mind is tricky isn't it? Have you considered that maybe the pills didn't work on you, maybe you just thought they did? The feeling what you have when you know that things will get better is powerful thing.

@aidanduffy7065 Год назад

@@MrGG-xc6sg nope. Look at the placebo trials. These are not mind over matter. They work, don’t know how but they work.

@Sl33pyDaron Год назад

You need jesus

@nomyt0766 Год назад

Nah I'm good for another year might go to one when I'm old enough to go alone

@chinchillainspace3624 Год назад

@@aidanduffy7065 did you not just watch a video on how they work

@rossplendent 3 года назад

"It is easier to say 'My tooth is aching' than to say 'My heart is broken.'" Tell that to the dentist I haven't visited in 8 years.

@blueorangeade3357 3 года назад

my dad hasn’t been to the dentiste in well over 5 years 😭🤟

@icannotcomeupwithanything4609 3 года назад

@@blueorangeade3357 My father hasn't visited the dentist for over 10 years..

@murdersuicide 3 года назад

@Ken Henderson what does that have to with anything

@yourfriendlyneighborhoodcl4824 3 года назад

@@murdersuicide hes a scammer

@sillybrisko 3 года назад

i havent been since i was 7 because i started getting severely depressed from bullying n im now 15 and i Still have not seen the dentist to

@mohammedsaquibkhan2592 3 года назад

4:25 simply put "Correlation doesn't imply causation" - Demon of Reason

@sergiobarros2697 3 года назад

- D. Hume

@jewelsoftheworld101 3 года назад

😮😍👍

@manikantan4809 3 года назад

Not simply put though.hard words

@dextro2090 3 года назад

I just want to point out how psychiatry always says something like: we have effective treatments for schizophrenia and serious mental illnesses, meanwhile, they don't even come close to understanding how they work; and you just need to get out and see the number of homeless in the streets; I mean they say we can treat it, while you just have to look at those patients and see that they are so-far from controlling the disease.

@josemorgan8048 3 года назад

correlation does imply causation;correlation does not equal causation.

@Crystyna03 2 года назад

I have just started my treatment and I can honestly say it's mind-blowing! I have been in therapy before but never had these results. For me, the most surprising part is not necessarily feeling good but the willingness to take risks, take decisions and make changes. Before this, I used to look around me and feel somehow trapped, like there was nothing I could do to change my situation, whereas not it seems as though my brain can find solutions.

@MrGG-xc6sg Год назад

That's it! When you think you are trapped you are just reinforcing the feeling/idea of being trapped. You need to think that anything is possible if you just put your mind in to it. Ones you got that you think that depression isn't real you put these walls over your mind that protect you from depression.

@criss6806 Год назад

What are the pills called?

@nini-he8uy 17 дней назад

@@MrGG-xc6sgyou’re weird

@garrettwidner6915 Год назад

It's not just psychotherapy and antidepressants, there are 3 methods for combatting depression and any doctor that doesn't explore the 3rd option is falling short. Lifestyle is the 3rd factor. If you're working 80 hours a week, living paycheck to paycheck, etc, you can't be happy. Some of this is beyond our control but you can't expect results if you give someone medication and therapy when they're in an impossible life situation.

@lawxs9114 Год назад

Blame capitalism then you Become marxist

@rimaoulhaj9910 2 года назад

Treating my anxiety disorder and depression has improved my life so much... I can never stress it enough. Get help people. It's not your fault. Don't feel guilty. It's an illness like any other.

@kaittlyn 2 года назад

@@oryuji2610 going to therapy is a good idea :)

@pieceofart5962 2 года назад

@@oryuji2610 what is the thing that makes you scared of going to therapy?

@bumblebeebrass164 2 года назад

Thank you, watching this video now so I can figure out what’s wrong with me. Been in therapy for a month, I think it’s time

@deniz8265 2 года назад

i went to a psychiatrist a few days ago and started taking two antidepressants. now i am scared that maybe i dont have depression and i fooled myself and the psychiatrist. maybe i just couldnt handle the sadness everyone feels and i am making a big deal out of it.

@sophiesleeps12 2 года назад

@@deniz8265 hey hey hey, stop that. If you feel sad for no reason and it lasts a long time, you're depressed. And a psychiatrist wouldn't just prescribe an antidepressant if you weren't really sick

@trtotally 3 года назад

Thank you for featuring mental health-related videos.

@nagarathnammats110 3 года назад

Ted ed hearted this comment So must reply

@Competitive_Antagonist 3 года назад

And for being so nuanced.

@maxine9263 3 года назад

@@toastycookies4703 sir why must you assume their indian

@redmist6630 2 года назад

ted ed finally figuring out us kids will only watch this stuff if its less than 5 minutes long

@sriku1000 2 года назад

A Calming Video On the Theory of Moving Emotions. Something as complex as you. You ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE--uexjy4sWu4.html"

@RossBilly 5 месяцев назад

Psilocybin DMT, mushrooms and psychedelics, as a whole, have shown substantial promise as beneficial agents that can truly aid individuals grappling with mental health difficulties.

@MilitaryStrong-vt2oe 5 месяцев назад

I totally agree! DMT, Psilocybin mushrooms and psychedelics in general have shown great potential in helping people with mental health issues. It's truly remarkable how effective they can be in treating depression and anxiety

@DannyFellon 5 месяцев назад

Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Italy. Really need!

@ThomasUrah 5 месяцев назад

I can say Dr.Jaffet is the man for you....

@DaveFarhat 5 месяцев назад

Dr. Jaffet has pure psychedelics products.

@YundaGregg 5 месяцев назад

How can I reach out to him? Is he on instagram

@LarthMedia Год назад

I’ve been taking medication and seeing psychiatrists and/or psychologists for over a decade. Trialing through different meds can be extremely difficult, I’ve had some rough days to say the least. My advice to anyone dealing with similar issues would be to never give up. The sun will rise on the perceived eternal darkness you are going through. Much love ❤️.

@grv91vr23 16 дней назад

Antidepressants are bad they disabled me

@ivanmont 2 года назад

Chemistry can be really complex and sometimes really scary. Much respect to those people who dedicate their lives doing scientific research so we can live a better life, at the end of the day they're the real life heroes.

@vincentschmitt392 2 года назад

they are criminals

@ishaanbhanushali3665 2 года назад

@@vincentschmitt392 and how are they criminals?

@vincentschmitt392 2 года назад

@@ishaanbhanushali3665 for instance by publishing fake results regarding the safety of some drugs. This is quite common.

@naynay8anaynay747 2 года назад

Even then, sometimes people get bad enough where they do end wanting to kill themselves. Although it isn’t correct, it’s what happens to some people. U can’t rlly argue abt it bc all ppl have free will

@naynay8anaynay747 2 года назад

I meant to reply to the comment below sry. My apolgies

@User-mp4vq 3 года назад

The art is so perfect, you can really see the sadness in the clients' faces. This is the reason I only watch Ted Eds animation. Thank you Ted-Ed

@bryce7889 3 года назад

I kind of think it missed the mark because depression is had by so many beaming and smiling people. Everyone gaslighted me when I said I was depressed because I “looked happy”.

@User-mp4vq 3 года назад

@@bryce7889 Wow, I am so sorry, there are so many different ways people deal with depression, and not every person is the same. I really like the animation because it is simple, but you're totally right.

@Yokasyan 3 года назад

Well, you can also watch kurzgesagt it is good too

@User-mp4vq 3 года назад

@@Yokasyan Really? Thank you for telling me, I love the birds.

@getonthecrossanddontlookba5004 2 года назад

Repent to Jesus Christ!!! ““Ask and it will be given to you; seek and you will find; knock and the door will be opened to you.” ‭‭Matthew‬ ‭7:7‬ ‭NIV‬‬

@richardwalker8575 2 года назад

I've struggled with depression for many years and had enough of anti-depressants and ready to try something different .

@patriciawalker851 2 года назад

`have you tried microdosing pills?

@richardwalker8575 2 года назад

@@patriciawalker851 `Can mushrooms/microdosing caps help for depression ??

@patriciawalker851 2 года назад

@@richardwalker8575 Yes

@patriciawalker851 2 года назад

@@richardwalker8575 Helped me alot

@patriciawalker851 2 года назад

@@richardwalker8575 \Willliamsmyco1/

@ghostlyxero9030 2 года назад

I've been depressed for well over a decade and it started in my early childhood years. Finally getting diagnosed and given antidepressants for the last 2 years has definitely helped me improve my mental health. Antidepressants do not take away my depression and anxiety, but make me feel less overwhelmed and more motivated to improve through therapy. there is always another answer, and it may not be the first one, but it is out there. for everyone dealing with their battles in private, i see and recognize you, and you are worthy and so so valid and deserving of getting help.

@user-dc4bl1cu2k Год назад

I'd reccomend checking your diet. If you're consuming caffeine, sugars, alcohol etc. your chances of overcoming depression are low. Just maintain a healthy diet and avoid stuff like that.

@supersnapp Год назад

Sounds like a very ineffective drug.

@voxifyszn2534 Год назад

@Shaun Snapp it's sad how people need medication because they sad

@goodnightmyprince6734 Год назад

@@voxifyszn2534 depression is more than being sad

@TristanSamuel 3 года назад

This isn't related to the topic but I like how everyone looks like they have a bird for a head.

@kwdmawdmwoa5668 3 года назад

oyasumi punpun

@_Hunar_ 3 года назад

Never watch this video before taking pills. 🔥

@hahalord7294 3 года назад

@@kwdmawdmwoa5668 Exactly what i thought

@blopin2002 3 года назад

Reminds me of Goodnight PunPun

@kwdmawdmwoa5668 3 года назад

@@hahalord7294 yeah i just finished it and i feel so empty inside now

@angiep.7253 3 года назад

My grandpa had depression and he committed suicide, I miss him so much. He did treatment and we thought he was improving, this illness is heartbreaking.

@lilyjay8530 3 года назад

I’m so sorry to hear that, may your grandpa Rest In Peace ❤️

@acrendon952 3 года назад

Im so sorry to hear that. I hope you get better soon

@sarfarazahmad1760 3 года назад

Suicide is self murder........ everything belongs to almighty God Allah...... So it is haram to commit suicide.....closeness to God makes you peace full

@Lokitellus 3 года назад

@@sarfarazahmad1760 yo7 shouldn’t say that because not everyone believes that stuff

@Lokitellus 3 года назад

@@sarfarazahmad1760 your welcome

@LazerAzxl Год назад

So far Prozac has given me a fresh breath of life after so many years in the deepest darkest pits of depression. I would go over and over and over with myself trying and trying to find ways to break out of that abyss but nothing every seemed to remove the root cause. After years, I finally feel like a normal functioning human which blows my MIND. I never expected it to have such an immensely profound impact on my mental state or health, it was honestly incredibly stigmatized from my initial standpoint.

@kathgarciaduarte Год назад

Depression is a heartbreaking mental illness and it can destroy the person and the people around way more than we imagine. I've been dealing with depression all my life and it wasn't until I started taking antidepressant medication that I actually realized what not to feel depressed feels like. I didn't know what it was like to wake up in the morning being energetic... I never experienced that until recently. I know depression it's part of me and I have to learn to live with it... It's hard but it's a relief knowing that there is a way to deal with it. Love to everyone out there dealing with depression ❤

@akiangel1864 2 года назад

I took antidepressants for 8-9 months, it helped me, and i eventually healed as time went by. Im glad to have survive depression and saved from the attempt of suicide. Here's a smiley face for anyone reading this >> •ᴗ•

@philip6502 2 года назад

Some depression is situational...death of someone close to you, loss of job, physical health. It will usually go away on its own or with medical/counseling help. Some depression, like mine, needs constant care...in my case, medication. I'm fortunate in that after years of trying, I have found one that works with minimal side effects. Every individual needs to find what works for them, but unfortunately, many don't try or are unable to. It's not an easy life.

@jazmin0511 2 года назад

Thank you for sharing your experience. I pray I can say this too one day

@thunderedsun203 2 года назад

why do these depressed people comment have to be so sussy 💀

@hussain0413 Год назад

@@thunderedsun203 it’s not sussy, if you were depressed you’d understand

@lalrinliana5966 Год назад

@@philip6502 hello philip i wanna talk to you

@sakurakokoro1567 3 года назад

Here's to all of us who take antidepressants to function normally and survive! You are not alone. You are all cherished and loved. ❤

@EvelynL.1112 3 года назад

Thanks

@h2o_exe 3 года назад

Thank you.

@limprofile 3 года назад

Used to take them for awhile. Im glad i dont need to depend on them for the time being now. But u all are awesome!

@quaimaboylan5175 3 года назад

i take citlopram

@herbertgamwell5364 3 года назад

Thank you! You’re not alone too ❤️ Together we all will reach our goals I hope so!

@alhaeri1 Год назад

SSRI have extremely dangerous side effects in some patients like suicidal thoughts, it is highly suggested that it should be taken with very high caution ⚠️

@sharpasacueball Год назад

That's pretty rare fortunately

@LE-qw5pl Год назад

@@sharpasacueball it’s not rare 30% of people won’t work for them, the war on drugs has heavily influenced the medical field as we banned many drugs without through research, this has left ssris/snris with the only thing doctors were prescribed and i’m not a doctor so i’m not the best at explaining this but ssri sometimes will have no effect on dopamine levels and it happens to a lot of people me included, but warning people of this is important bc most people take medication as their last option and think something is wrong with them if they can’t be happy on antidepressants then the won’t be happy at all, which can lead to suicide , so it’s important to tell people that ssris aren’t the end all be all

@ianfoster9538 2 года назад

This is the first time I haven't learned a lot I didn't already know from a TED video. It just made me really grateful I have great people like family and doctors around to help educate me, and not everyone gets that :)

@shayarhashim7567 3 года назад

I am on antidepressants and i am proud that i have face the reality and went to fix my life, please don’t be ashamed when you need help ♥️

@kaynatnasar1564 3 года назад

Same . finally took the step towards medication after suffering for 8 months

@Zwerlijn 3 года назад

Well said, sometimes you need a bit of help, i was on them for 7 years. Made a lot of lasting changes in that time and learned to love and respect myself above all else. Now off the meds since a year and even though life still throws difficulties at me at times its much easier to deal with them

@shayarhashim7567 3 года назад

@@kaynatnasar1564 I am very proud of you to take that step to live a better life now.

@shayarhashim7567 3 года назад

@@Zwerlijn That is really inspiring to hear, you have done so much to make your life better and i think you are now living better than that before 7 years ago, there is no shame for knowing that life could be better until you see the difference after you heal your mental diseases. Thanks for sharing! I am very proud of you.

@loriescalera 3 года назад

I am proud of you too. There is no one size fits all. I have seen a lot of suicide. I have seen a lot of mental anguish and illness. I, myself, will always try to improve myself when "I am AWARE" that something could be better. Its not easy, but I want to live and be creative, so I embrace struggles.

@mind7938 3 года назад

it's my first time taking antidepressants and i've never felt this happy (?) in years !! i literally was so shocked when i realized why bad thoughts were being suppressed / weren't being processed further, i remembered i took an antidepressant earlier. it's still weeeeird. i'm also a chemistry major but i really stopped studying it a few days ago because i was so unmotivated and probably lost passion. but i slightly got motivated seeing the chemical compounds in this video. perhaps i wanna make people feel what i felt and help them too

@NotAnti2 2 года назад

Hello! It’s been 3 months since your comment was uploaded. Has everything been okay regarding the consumption of AD? I want to get on them but I’m worried it’ll make it worse, doing my research still. Hope all is well along w your passions and drives!

@jones2277 2 года назад

how long did it take for it to work for you?

@myaaisha3147 2 года назад

Yea it makes you smarter also and make you realize things you never did before. It’s a different perspective the way you see things. When you’re happier, you function better.

@myaaisha3147 2 года назад

I don’t take a dose everyday just whenever I’m in a bad mood

@mind7938 2 года назад

@@NotAnti2 hi! in my case, there have been no problems so far, really only benefits from the medication. i still take them everyday but my dose was halved recently. but of course we probably have drastically different cases and our response to the medicine would also be different. again, i don't think and feel i experienced negative effects from the medicine. while antidepressant dependence could be a concern, i personally haven't faced the problem, but i also think i really wouldn't as long as i abide by my psychiatrist's instructions. what i learned, however, is that antipdepressants really are only a part of "getting better." factors like lifestyle, mentality, and your surrounding environment are just as important. with that, i just wanna emphasize that antidepressants did help me, but i could still not improve when i still have problems with those other factors. what i do suggest is for you to visit a health professional and when you've received the proper medications and encounter any problems with it, you just have to tell them and they will make necessary adjustments. in my case, all visits had been a share of responses to the medication and adjustments in return.

@AliceP. Год назад

4:11 - 4:28 this seems like quite an easy riddle to solve. Serotonin deficiency doesn't cause depression, the situation/pressure/life in which one finds itself in does, but serotonin acts as an artificial "glass half full" feeling that makes a person have the will to live and eventually face their issues

@anywallsocket 2 года назад

Bro the monolith casting spiraling shadow on “we still have a ways to go” with “understanding” at the middle 🤯 Animation artistry 🤩

@bull3tride 2 года назад

As a victim of the above mentioned I can truly say that I would have taken my life years ago if it was not for therapy and medication. Do not be afraid to ask for help. A life with untreated depression is no life at all.

@crowdise499 2 года назад

Ah so I have no life *Great*

@Connorscarlos 2 года назад

I am going to get on medication due to this, I am suffering every day now with physical symptoms manifesting. My family thinks I’m dramatic but I have had enough

@tonyd.u.y7262 Год назад

@@Connorscarlos How are you feeling now? I tried therapy but that didn't really work. I'm think of taking medicine since I find myself getting closer to actually suicide.

@MrGG-xc6sg Год назад

@@tonyd.u.y7262 have you considered that your depression is caused by you life choises? Like if you change your life you wouldn't be depressed? Like you don't have the thing that drives you in your life. Ones i found that i have never felt better. So my advice for you stop thinking negatively go for runs, start working out (strong body equals strong mind), start new hobby, listen motivation speeches, get quality sleep, eat healthy and reduce time on phone.

@sigmamale4147 Год назад

@@MrGG-xc6sg i agree 100%, life choices were very important for me

@sid-2k1 3 года назад

I liked how the pup was giving instructions to the scientists to prepare drugs for depression.

@dylanparker130 3 года назад

Haha, love this comment!

@Tree_Lord 3 года назад

Who better to create anti depressants than one of the most anti depressing animals.

@ladygrinningsoul357 3 года назад

So that's what the dog was doing.

@htsgm 2 года назад

@@heckerjr.7982 no

@monicayami2298 2 года назад

@@Tree_Lord love this haha

@Mattrero 2 года назад

This channel answers questions I never asked myself. Thanks!

@JMPM1 2 года назад

Reminds me of a joke: "to whoever stole my antidepressants pills, i hope you're happy now"

@Munthegun 2 года назад

Lied to myself for 15 years about depression. Even made specific doc visits for it and lied to them, leaving empty handed. Finally openly expressed my emotions and got on antidepressants and it was the single best decision I’d ever made. Literally life saving. I call it the logic pill. Life is wildly better three years later heavily thanks to starting them.

@tabularasa9576 2 года назад

Why did you lie about your depression?

@angelit0es Год назад

@@tabularasa9576 its embarrassing to receive sympathy or pity for some people its why i lied about self harm as well.

@adelmograziano2506 Год назад

It was the opposite for me. I was having depression, but antidepressants destroyed me. I can't feel emotions and every aspect in my life is ruined. I suspect neurotoxicity. It's affecting thousands of people. I'm glad they helped you, but they can come with life ending consequences. There are alternativee cures for depression, but there's no cure for this condition.

@SARCASMOOO 4 месяца назад

Yeah the thing i find so difficult since i am on anti depressants is trying to explain what it is like and people tell me just do it anyways. Like thanks that helped so much.

@justsomeoneelse5942 3 года назад

I haven’t even finished the video but the animation is so good...

@praveensheelvant6061 3 года назад

You haven't finished the video because you wanted to post the comment.

@thecreatorofpc7929 3 года назад

And so is the background music

@Abstractor21 2 года назад

I dont know why but it reminds me to Pathology 2

@livyrose002 8 месяцев назад

i was diagnosed with depression 3-4 years ago and have been on anti-depressants since. they saved my life man

@AZMaybe Год назад

1:40 The way they suddenly look at you...

@xzyhavionwilliams5058 3 года назад

Ted Ed is my antidepressant because whenever they show up I’m happy

@kingsley. 3 года назад

@pixelpancakes489 3 года назад

That was smooth-

@HunterSuper 3 года назад

You are saying this for likes aren't you

@CatHostage 3 года назад

Yes, i need TedEd videos in order to get out of bed in the morning too

@bernae1902 3 года назад

Depression isn't not being happy.

@jakuxsi 3 года назад

Great video! I'm always annoyed when people say that depression is "just an imbalance of chemicals in the brain" when it's much, MUCH more complicated than that.

@raph2550 3 года назад

A personal example: what if the side effects of the antidepressants given to treat your depression create new problems in your life, which thus fuel your depression?

@crazydragy4233 3 года назад

To be fair, sadly that sort of thinking is the lesser of 2 evils at times...

@Kier4n99 3 года назад

Can you enlighten me? As that is pretty much what I think.

@jimiplayscobo5877 3 года назад

@@raph2550 Then you tell your doctor to prescribe a different script. What works for one may not work for you :-) Peace

@raph2550 3 года назад

@@jimiplayscobo5877 Yeah, sure, but that may take a long time =/

@gastly2109 2 года назад

It was very sweet to include an animal with the people who experienced depression in the video ! Very nice :)

@leonielopes7586 2 года назад

Love the animation in this video. Complemented the topic really well

@cameronukz 2 года назад

I think a lot of people take them and expect to just feel better which doesn't happen. They just make your mood more stable so you can actually work on the issues that are making you depressed or anxious without feeling crippled by panic and stress.

@MrGG-xc6sg Год назад

True, like depression is always the symptom of something. People trust too much for pills to fix everything but at the end you are the only one who can fix your own mind.

@s.o.s7180 Год назад

@@MrGG-xc6sg definitely agree, i dont believe in the power of these pills. Something artificial wont help me, I prefer nature.

@paintwithtihani9926 3 года назад

You can dance or you can cry but still the sun will shine on you 🌻 all love to the fighters out there, you know who you are

@itsbutterfai 2 года назад

Thank uuu❤️

@purplemismagius28 2 года назад

Prozac is a miracle pill, I was constantly panicking and scared whenever I was alone; but when I started Prozac I suddenly was able to live to my true potential.

@znrdn 2 года назад

Meow meow 🐱

@Serennekin 2 года назад

what dosage are you at?

@emberhermin52 2 года назад

That makes sense. It made me feel so dead and numb when I was on it, but if you needed an emotional "deadening" effect...

@purplemismagius28 Год назад

@@Serennekin I’m currently at 30 mg

@phillipsmith4485 Год назад

Placebos work just as well to help you recover.

@sanuspg 2 года назад

I love the graphics style in this animation. Also, thanks for this informative video. More than 15 years with depression, I'm on meds, and I've had a long therapy, both very helpful, but it still affects my life, and I still try to learn more about it.

@mehakjan6996 Год назад

Are u ok now

@sebastianc2222 2 года назад

I like how we are still at a point of history where we don´t understand how some stuff works but we kinda just go along with it cause it works.

@KikaJoye 2 года назад

i feel like few years later or maybe when our generation will be old there will be more informations and maybe ad will be seen as damaging like it happened many times before with cigarettes, alcohol during pregnancy or so on when we were not aware about bad effects at all

@RetroPlus 2 года назад

Just remember that only 50 years ago they still performed lobotomies

@aplus1080 Год назад

That's medical/scientific history in a nutshell

@suaiedail Год назад

Scientist are still not sure what the mechanism of action of acetaminophen/paracetamol is, one of the most used painkillers

@astromessier Год назад

We would know if the 2 trillion dollars we spend annually on the military were used for scientific research.

@Ellie-jl3vk 3 года назад

Don't let anybody talk you out of giving antidepressants a try if you need them. I avoided them for 5+ years and giving them a chance saved my life.

@AndyCouch3000 3 года назад

Same goes for psychedelics

@juleslloyd9162 3 года назад

I second this!

@deshaunblackett4745 3 года назад

Therapy and a friend is better than meds

@Ellie-jl3vk 3 года назад

@@deshaunblackett4745 Go away

@Justanobodybro 3 года назад

@@Ellie-jl3vk no just facts

@aimeejane_writings Год назад

I find it sad how we live in such a depressive society and deep down everyone knows this but because of conditioning etc, we haven’t been giving the correct resources to fix this but instead, have just been prescribed drugs to cover it up. Yes, antidepressants may help someone feel happier, but it doesn’t get to the root of the issues at hand. It’s an utter shame

@CarlosPerez-mn5gh Год назад

I recommend the use of psychedelic mushroom it’s all natural and it’s the best to cure anxiety and depression , I can’t remember when last I felt depressed, I was depressed until I got my hands on psychedelic mushroom, I was in pain and confusion now I work effectively and efficiently without worry and fear of the unknown, I get mine from an online vendor that specializes in the growth and sales of psychedelic products , it makes you see the truth and understand every situation

@CarlosPerez-mn5gh Год назад

*Formulah*

@allrounderalltime5838 Год назад

The animation in this video is outstanding ❤

@anotherone8941 2 года назад

"we don't know what causes depression" tell that to parents who think if the world didn't explode you can't be depressed

@nastya0987 2 года назад

Its hard for people who never experienced depression to understand it, that doesnt mean they are bad people, it just means that they dont understand it. You cant be mad at a man not being to understand extend of pain women go through during birth giving. The common point needing to be delivered is that its an actual illness that has nothing to do with events one may be experiencing.

@otundetchagala9560 2 года назад

As someone who overcame depression by himself, I'd say if you aren't some sort of cripple, you really have no reason to be depressed.

@leon3672 2 года назад

Parents should be totally aware of mental illness beforehand, since they introduce their children to all suffering by giving birth and play a big role in their development stages

@otundetchagala9560 2 года назад

@Chilapa That sounds like a character flaw more than anything else. Being loved and loving in return isn't something that should make you extatic 24/7. I'd say you either lack appreciation/gratitude for the people you already have in your life, or you just don't really like them that much. I'd suggest reflecting on your own thoughts and feelings before jumping on the antidepressant train.

@lanatureestlartdedieu9591 2 года назад

@Chilapa I agree

@carlogaytan7010 3 года назад

What I got from this is that we are pretty advanced in treating the symptoms. But I've rarely seen someone talk about curing this, nevertheless, preventing it in the first place.

@ohioskane363 3 года назад

Eliminate childhood poverty and abuse, eliminate sexism and racism, and in some cases choose different ancestors.

@binita4672 3 года назад

@@ohioskane363 wtf do u mean by change ancestors

@KeanuG95 3 года назад

@@binita4672 just change your great grandparents, how else?

@ohioskane363 3 года назад

@@binita4672 Having grandparents who have undergone trauma increases susceptibility to depression in the grandchildren. Not practical advice, of course. 😉

@LaurennM360 3 года назад

Mood disorders are hard to regulate. It’s not something you just cure. I would say we aren’t that advanced. Unfortunately like he said lots of people don’t respond to medicines, but there is still a lot of doctors who just want to throw medicine at the problem and not address other issues that could contribute. (Socioeconomic status, level of support groups, behavioral, nutrition, other disorders, etc.) I was on prozac as a teen for many years. It was seen as a catch all at the time. Now I see a psychiatrist and take different meds that are a little more helpful for me. But let me tell you there is SOOO much that contributes to depression and anxiety. (Vitamin D, anemia, thyroid issues, people around you, exercise, thought process, trauma, other mental disorders like ADHD, anorexia etc,) A lot of times it is a side effect of something else going on. 🤷🏼‍♀️ Mood is hard to quantify. So it’s also harder to study. Harder to treat. Not everyone experiences depression the same way. There isn’t an easy way to “cure” depression. It’s mostly about improving your level of daily functioning.

@elementalsteve9029 2 года назад

I really loved the animation in this video. It matched the lesson really well.

@hsaqib8995 Год назад

Thank you for sharing.

@anxiousleighwaiting 3 года назад

A quote fitting for this video: "If you don't have your own serotonin, store-bought it just fine."

@Dosia142 2 года назад

"but that doesn't mean seretonin deficiency is cause of depresion"

@elenapashaeva1 2 года назад

But it’s true what they’ve said - it doesn’t help everyone. Fluoxetine did nothing to help me with my depression. But helps to get absolutely hammered when you mix it with alcohol. And then you are becoming even more depressed. Changing my life, turning to God, doing good things for others - that is what really helped me.

@drot13 2 года назад

Abigail? :-)

@juanignaciogregoratti8606 Год назад

@@Dosia142 😂

@johnm.7611 3 года назад

I was on Sertraline and Fluoxetine therapies to treat depression but none of them helped me recover. On the other hand, I had severe side effects such as weight gain, headaches, insomnia and nearly developing diabetes. Therefore, it was not worthy taking them. Unfortunately, depression is more complex and just antidepressants aren’t the answer to the problem. If a patient suffers from unresolved trauma, medicine won’t really help. That’s why talking therapy with a psychologist is mandatory.

@meeshterious8644 Год назад

Sadly, the psychiatrist I went to has zero compassion for her patient and uses non-therapeutic communication approach. She does not even pay attention to what I am saying, just asking me sypmtoms from her checklist and prescribed medications. She was in a hurry maybe to be able to take in more patients. My intial session with her took only maybe less than 15 mins.

@bartpeeters2029 Год назад

Brilliant and very valuable info done is a masterly fashion. Love the design too. Impressive.

@fxaman 3 месяца назад

I'm glad to learn more about this. I've been stuggling with depression (undiagnosed, just how I would describe it) for the past eleven years and lately all I could thing of is suicide, so I'm going to start therapy next month and I have first appointment to psychiatrist at the end of this month. At this point, I'd give anything for an option to feel joy again. I hope combination of therapy and drugs might work for me. I'm losing hope, but we'll see.

@tuanz8009 3 года назад

I used to have anxiety disorder. Ever since taking antidepressant medication I feels like I just came back to life

@zuzannakielar 2 года назад

Samee

@houseoffirebellytoads1439 2 года назад

Which one are you on?

@Empr.Palpatine 2 года назад

Do these pills make you feel "Sedated" in any way? because i have considered antidepressants. But i am afraid that I won't be able to learn things as easy or concentrate as long as before.

@juligarcia23 2 года назад

@@Empr.Palpatine no, and if they do your psychiatrist will find a better drug for you

@Empr.Palpatine 2 года назад

@@juligarcia23 ok. Thank you :-)

@kerentan9446 3 года назад

that guy holding up the "It's not your fault" billboard is my antidepressant

@sugahoney4826 2 года назад

Im here bc I'm about to start taking antidepressants but I wanna talk about this whole illustration, it was so so cool and creative, love it. Hope im gonna get better and start drawing again

@ThaTrisme 2 года назад

Did you start taking the medication and which one are you taking, also are you feeling better yet has it any side effects I'm asking because I'm also gonna start taking them

@user-go6dp8bq8c 2 года назад

Wow! The animation style looks realy interesting, animators did a great job

@ellet8529 3 года назад

This makes me feel better, I've been on antidepressants since age 14, and now at age 22 I'm looking to make steps to come off them! It's nice to hear that there's hope that I won't need them again

@lisahansson2605 3 года назад

Check out Kelly Brogans book A mind of your own.

@ellet8529 2 года назад

@Warped Sounds TW suicide and self harm. I mean I was suicidal so I'm not sure what the doctor could have done - he sent me to counselling but the NHS provisions aren't great and so I fell through the cracks unfortunately. I came off them for a short time at the start of university but my self harm tendancies came back and so I requested to be put back on them. I'm in a much better place now than I was back then though. I don't know if I appreciate you saying it's a phase, I have good days and bad, and I expect that will continue through my lifetime, but hopefully I'm more well-equipped to deal with it. Hope this all makes sense!

@chelsealouise2232 3 года назад

the animation on this deserves an award

@guidaribeiromap 2 года назад

Excellent content. Thank you.

@alexaclaire8728 Месяц назад

I have PMDD. The fact you explain depression as a chemical imbalance just blew my mind! The drop in hormones right before menstruation makes a lot of sense it could inadvertent cause a chemical imbalance. I hope we find out more about this disease in my lifetime

@esma1456 3 года назад

We need more videos of "There's a Poem for That" 🥺💜 You completely forgot that series..

@tonykhang1984 3 года назад

yes

@treve.mp3 3 года назад

YES! Seconded.

@little_swallow 3 года назад

Agreed

@chocolatymilk2402 3 года назад

I agreeee

@eirenec.m.9496 3 года назад

Definitely!

@ssff4066 3 года назад

It is easier to say 'My tooth is aching' than to say 'My heart is broken." It has been 20 minutes and I am still thinking about this line. 😌 so perfect

@greteohneh4503 Год назад

I absolutely wish i would have seen this video 3 years ago, when my therapist at that time wanted to treat me with anti depressants so badly. But i refused, because i was against something that would help my condition or get out of it but my own abilities . Now, i moved, stopped therapy, and lived through the worst weeks of depression, but have no access anymore to the meds.

@FredSlocombe Год назад

I took Fluoxetine for a couple of years and it improved my mood to the point where I was remembering positive experiences from my childhood that I couldn't remember before. However, this was in the run-up to the Covid-19 pandemic. I was unable to modify my habits and make necessary social changes in my behavior.

@burhbruh1786 3 года назад

Wow, huge props to whoever animated this. I loved the art style, the drawings, the characters, the aesthetics. EVERYTHING!

@crispin9152 3 года назад

Jumped onto this video very quickly. Not only do I work in medicine and have a good understanding of depression and SSRIs, I too suffer from depression and went through trial and error of trying many kinds of medications. I hope that in the near future, we can have a better understanding of it's causes, functions, and treatments as well as eliminate the stigma behind it. Thank you TED-Ed for spreading awareness through your massive following.

@shyaaammeneen63 2 года назад

Crispin, If depression affects physical health like nausea, upset stomach etc medication of a low dosage is needed but under guidance. Detox your mind. Reduce negative thoughts. Your breath is directly related to your mind [brain] causing negative thoughts-anxiety. For a relaxed life sit on a chair, back erect, eyes closed, be still and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for around 5-10-15 minutes or more. Don’t fight with your thoughts. Slowly they will reduce and relax the mind. Deep inhalation-exhalation is not needed. Anytime of the day or night before sleep sit or lie down and observe your breath. Be as still as possible as it reduces negative thoughts. Make this a lifetime daily habit to have a good life. Best wishes Shyaaam Sir. -Counsellor

@nataliastead7221 2 года назад

In my experience antidepressants made me feel nothing at all, they made me somewhat numb. Although I wasn’t in a state of sadness and having to deal with anxiety every day, it also stopped any excitement or happiness overall. I’m not on them anymore but they did help me overcome lots of things and I did see overall improvements

@Am0ha Год назад

I hope u told them it made u feel numb 😅

@phillipsmith4485 Год назад

Yes they depress some brain functions and numb the emotions, good and bad. Overall not good at all except for a very brief time.Even then placebos are as effective, and love, support,care, financial help friends and relatives can do much more without side effects.

@meeshterious8644 Год назад

Hi Natalia. Glad it helped you. May I know which antidepressant did you take and for how long? I am apprehensive about it’s side effects. It seems like it can create more problems than the benefit.

@Jordieeee304 Год назад

TedEd needs to do an updated video on antidepressants. We now know that antidepressants have a placebo effect on depression.

@nxcrorat 3 года назад

I struggle with depression amongst other things but since I had bad experiences with doctors it's becoming harder to trust them and their prescriptions, thank you for this video, it will definitely help me.

@alexanderveritas 3 года назад

Well, I’ve been using antidepressants for some time now and I can say that this particular video has undeniably shed more light about comprehending my actual condition.

@edwardwrightlambert1608 2 года назад

been battling anxiety, depression and insomnia but getting to meet *Healermanchris* on IG who sales DMT, Shrooms, LSDs and other psychedelic products. I have been effectively stable and relaxed, he ships discreetly worldwide 🚚

@shyaaammeneen63 2 года назад

Alexander, Detox the mind. Reduce negative thoughts. Your breath is directly related to your mind [brain] causing negative thoughts-anxiety. For a relaxed life sit on a chair, back erect, eyes closed, be still and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for around 5-10-15 minutes or more. Don’t fight with your thoughts. Slowly they will reduce and relax the mind. Deep inhalation-exhalation is not needed. Anytime of the day or night before sleep sit or lie down and observe your breath. Top priority is to be as still as possible as it reduces negative thoughts. Make this a lifetime daily habit to have a good life. Best wishes Shyaaam Sir. -Counsellor

@penguinsmalz3774 2 года назад

I've been taking SSRIs for over a month and they work. I live in a toxic household so I don't have the support I need. My meds stabilize my mood. I can't feel the extreme of any emotion. I am an artist so my imagination has also decreased. I haven't had a mental breakdown or the shooting chest pains(anxiety) since. This is not something I'd do long term but until I can get out of here, these are a lifesaver.

@Arya-db3yd 2 года назад

As someone who's been taking fluoxetine for about 2 months now, i really appreciate this kind of video! i love understanding more about stuff like this...

@sergeychekoev6377 2 года назад

Share with me?

@Arya-db3yd 2 года назад

@@sergeychekoev6377 share what?

@sergeychekoev6377 2 года назад

@@Arya-db3yd In your comment, it is said that you have been taking Prozac for 2 months. In your comment, it is said that you have been taking Prozac for 2 months... So I say, share with me? I also started taking Prozac.

@Bean-hm4ob 3 месяца назад

@Arya-db3yd I think he meant your experience

@alcrian8627 2 года назад

I'm on an ongoing psychiatric / psychological treatment for burnout. The anti anxiety medication I have also happen to be anti depressive. Around two weeks ago I tried to end my life - I had no prior suicidal thoughts in my life and I think this was solely a result from the medication. I took the decision to stop taking these medicines without consulting my psychiatrist / psychologist a day after because I was afraid of it. It was the worst decision in my life... I started to have suicidal thoughts everyday, I felt like I was drunk most of the time, rashes on my abdomen appeared and I simply couldn't sleep. The doctors then said that I should take the medicine as soon as possible and then I did... I'm on a license of 15 days from my job and I'm gradually getting better. The suicidal thoughts stopped and the rashes are gone. It's honestly terrifying how a medication that affects your brain can affect your body and your life.

@ploofish82 2 года назад

Is this really true? I’m on anti depressants and after 2 or 3 days of forgetting to take the medication I have a strong urge of suicide and random impulsive behavior

@jemmas5197 2 года назад

@@ploofish82 it is true. It is why they say on the packet to consult your doctor before taking stopping antidepressants. You should always slowly lower your dose if you are going to stop because stopping all at once will cause a worse reaction than you were experiencing beforehand. It can be very dangerous. I start getting really sick and suicidal two two three days after forgetting mine. I have an alarm set every day to take them at the same time because even if I take it a couple hours later I still feel a little bit sick after a while. Always consult your doctor when stopping medication or increasing your dose.

@alcrian8627 2 года назад

@@ploofish82 unfortunately, it is true. My psychiatrist always advise me to not stop the medication abruptly. You'll have to try to keep a routine. Everyone's different so you'll have to try whatever suits you best. This is what I did: I've created an alarm on my phone to take them. I always bring them with me if I go somewhere just in case I'm not at home in time. Also, if I forget to take them for some reason I take them as soon as possible.

@alcrian8627 2 года назад

@@ploofish82 one more thing: I know it's difficult but you'll eventually get better. If you need anything, let me know.

@hetedeleambacht6608 2 года назад

@@Another-Address did you try to find a very good therapist?

@citroken 3 года назад

I loved the little dog keeping the person company throughout the video ❤️ Reminds me of my dog throughout my own journery

@GrantCopping-brown-bs2hw 9 месяцев назад

Very well done and ❤️felt applause for this video , I thought the way it was done by pictures & very nonjudgmental, I’ve been suffering Depression, anxiety, memory loss ( & probably bipolar ) for years ,& a lot of the ( & in layman’s terms) way things were told/ advised were excellent., 👍😎

@lethalsands 2 года назад

I just got prescribed prozac, thanks for the helpful video.

@tobymax10 2 года назад

I just switched school and felt (still do a bit) depressed. I found working out to really help with it. It gives you a better body which feels nice, but you also feel great leaving the gym. Knowing that you put effort into improving your life feels good.

@sinkpisserpro 3 года назад

The art and animation in this episode is absolutely gorgeous!

@MrAndreisousa 2 года назад

thanks for this video

@Queening Год назад

I find studying the brain's chemical ratios and balances so interesting. It's so amazing we can give people special amounts and kinds of medication to balance out the brain.

@LilVukie 3 года назад

Everyone needs to read Lost Connections by Johann Hari. It will completely change your view on depression and anxiety. It is an amazing book

@shaymaeel-jaouahiry6278 3 года назад

i am gonna read it

@LilVukie 3 года назад

The audiobook of it on Audible is great. Hari reads it himself

@brunonotthemars7856 3 года назад

I'll check it out. Thanks!

@chocolatymilk2402 3 года назад

Thank u for the suggestion, been lookin for books about that topic :)

@LeonhardWindecker 3 года назад

10/10

@seulgisjoy7439 2 года назад

My childhood best friend I haven't seen in a while has depression now and she's in a psychological clinic... She's only 14. I found out last week when I visited her again. It's so heartbreaking to see the joyful smile vanishing from someone's face... She already told me a while back that she wasn't doing all that well and plans on going to therapy, I comforted her and reassured her that therapy will help and everything is gonna be Allright! But I didn't think it was this bad anyway... I feel guilty for not staying in touch. I'm so worried

@balladofthebroken7569 2 года назад

Out of the 7 I tried, they don’t work for me & instead make me a walking NPC with no genuine raw emotion. Also, some of them (such as Zoloft) lower your risk assessment drastically which can produce disastrous results in certain individuals (James Holmes). Speaking for myself personally as someone with depression induced by generalized anxiety disorder & PTSD: I am not a fan. Working out, socializing with others, a stronger sleeping schedule, a productive day, etc. benefit me much more. Thank you for coming to my Ted Talk El fin

@sandraallysa 2 года назад

Anti-depressants worked so well for me. It made me feel like myself again. But my family can't afford them, so I just try to function like a normal person.

@joshnorman7234 3 года назад

I wish they also talked about the other classes of antidepressants, like SNRIs and atypical antidepressants- the ones I am on. Still, very informative and awesome!

@maboroshi2550 2 года назад

I am diagnosed with dysthymia since January 2019. I have been on medication with escitalopram and clozapine. This was a hard time. I just lost my job then searching for a new one. My health still wasn't stable from the past traumas I had four years ago. Depression has always been with me in the silence of my heart. Now it's 2021. Still on meds... and am hoping the clouds in my mind will clear out soon.

@Tommy712rus Год назад

Try to learn yourself instead, eastern methods

@cactusboris2042 2 года назад

The animation is amazing 💜

@MissKareeBaby331 2 года назад

very helpful video

@billycasper3351 2 года назад

The articulation of the concept is top-notch.

@isaac3521 3 года назад

Hello, I'm loving this channel, a big hug from Brazil 🇧🇷

@nicolemills4795 2 года назад

Great information!

@jonathan1100 Год назад

This animation is beautiful.

@Akash14. 3 года назад

“Its easier to say ‘My tooth is aching’ than to say ‘My heart is broken.’” 14 year old edge lords: “Are you challenging me?”

@MartinPradoGuerra 3 года назад

Where do I download the funny out of your joke?

@hastagmjolk2527 3 года назад

@@MartinPradoGuerra you are the person who is able to roast roasters

@misterminutes4504 3 года назад

@@MartinPradoGuerra You will save humanity from destruction and extinction.

@BrotherV07 3 года назад

@@MartinPradoGuerra even I felt the heat from that

@bruhboi4692 3 года назад

@@MartinPradoGuerra You are the chosen one

@ramanrendersrandomly 3 года назад

Ted-Ed consistently churns out vids with different animation styles and I love it.

@lilyblossom9438 Год назад

I actually take Prozac! It's more for anxiety than depression though. I remember first going on it about 5 years ago and the difference was night and day. Cool to hear the history behind it!