How mRNA helped save lives: DNA Transcription: Crash Course Biology #34

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You’ve probably heard of mRNA, thanks to the COVID-19 vaccine. But what is mRNA exactly? In this episode of Crash Course Biology, we learn about the role of messenger RNA in living things and how it decodes our DNA instruction manual through transcription.
Introduction: mRNA Vaccines 00:00
Messenger RNA 1:21
Transcription 3:48
Processing & Splicing 5:05
The Central Dogma 7:00
Alternative Splicing 8:39
Review & Credits 10:46
This series was produced in collaboration with HHMI BioInteractive, committed to empowering educators and inspiring students with engaging, accessible, and quality classroom resources. Visit BioInteractive.org/CrashCourse for more information.
Check out our Biology playlist here: • Biology
Watch this series in Spanish on our Crash Course en Español channel here: • Crash Course Biología
Sources: docs.google.com/document/d/1G...
***
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Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
Leah H., David Fanska, Andrew Woods, DL Singfield, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Burt Humburg, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Breanna Bosso, Matt Curls, Jennifer Killen, Jon Allen, Sarah & Nathan Catchings, team dorsey, Bernardo Garza, Trevin Beattie, Eric Koslow, Indija-ka Siriwardena, Jason Rostoker, Siobhán, Ken Penttinen, Nathan Taylor, Barrett & Laura Nuzum, Les Aker, William McGraw, Vaso, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Pineapples of Solidarity, Katie Dean, Stephen McCandless, Wai Jack Sin, Ian Dundore, Caleb Weeks
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Опубликовано:

27 май 2024

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Комментарии : 41

@sebali-ferguson6303 2 месяца назад

CrashCourse BIOCHEMISTRY WHEN?

@mattkuhn6634 2 месяца назад

Dr Sammy continues to be amazing - that "devour a good book" line had such excellent delivery it had me laughing for minutes!

@trevinbeattie4888 2 месяца назад

It’s amazing to me that biologists have learned how DNA/RNA works well enough that we can now splice genes and manufacture mRNA fragments so we can treat a number of diseases and disorders this way.

@romanatorx3949 2 месяца назад

Yay! As a bioinformatician working with a lot ofnRNA data I can send this video to my students.

@adpirtle 2 месяца назад

The molecular machines that operate away in our cells are so fascinating.

@pinktights747 2 месяца назад

Thank you for the free education. I payed a small fortune at the University.❤❤❤😂😂

@adamphilip1623 2 месяца назад

Loving this series, really informative, fun and engaging and that's coming from someone who has always struggled to really engage with cellular biology in particular. Also I love the host choice, Dr Sammy is great!

@Iceberg_maal 2 месяца назад

Oh I can't wait to read these comments 😂😂😂

@adamphilip1623 2 месяца назад

Really good coverage of the covid vaccine for this context!

@AjayKumaR-vd1gy 2 месяца назад

💯 my research interest topic 😀

@Teo117 2 месяца назад

Phenomenal description!

@gregmiller9710 2 месяца назад

i was totally unaware of how the covid flu shot worked...now i might get one because i haven't yet due to allergic reaction to the shingles vaccine.....thanks for the education ! :)

@gailaltschwager7377 2 месяца назад

Thank you!

@ich3aa 2 месяца назад

Hey, good video

@sweetcreemaker 2 месяца назад

I love science ❤

@turtler3603 2 месяца назад

i'm too early for the translation video when my test is in a few days :( unfortunate but this video was still helpful :)

@bvillafuerte765 2 месяца назад

Good video.

@andrewp6738 2 месяца назад

Hell yeah

@starc. 2 месяца назад

fantastic video can you follow it up with more?

@nebulan Месяц назад

8:41 what science is about

@jawaharkonathala6950 2 месяца назад

Can you please give examples which help students from other countries also to understand? Like I didn't understand the platypus playground.

@culwin 2 месяца назад

Platypusses aren't native to America, and I can still understand just fine. If you still don't know what a platypus is, you can use a popular search engine such as Google to find out about them. I don't think it is necessary to understand anything about the video, though.

@Clownworld37 2 месяца назад

My heart!

@pcxPOT 2 месяца назад

myocarditis?

@beo_freo 2 месяца назад

Unrelated question, but are those jellyfish in the background real? :c

@wissam_fares 2 месяца назад

👍🏼👍🏼

@Nick-zp8wk 2 месяца назад

So uhhh, why did Hank stop hosting again? 🌝

@mashrabjonqoldoshev2599 2 месяца назад

@Denise-ux4xd 2 месяца назад

BI🛑WEAP🛑N

@user-kh2fs2sv5y 2 месяца назад

As king David under inspiration said we are wonderfully made.. praise God Almighty

@Noobahmastah 2 месяца назад

This and HurkaDurrGesagt are transparently prop-up-ganduhrr at this point.

@an740ny 2 месяца назад

"helped save lives" 😅 🤨

@floatingleaf9672 2 месяца назад

It is important to add any risks involved in such a crash course; IMHO it is irresponsible not to. Please research off-target effects. Any potential risks involved should also be mentioned so that we can be informed. Or maybe there are no risks? But that is unlikely and certainly long term unknown. Thank You!!

@gqsnowman 2 месяца назад

But this is about the technology and how it works. The potential risks of treatment will differ wildly depending on what application it's used for, how it's delivered, and a ton of other factors. What you're asking for is like asking for every potential bad thing that might happen on facebook on a video about how the internet works.

@raidwipe 2 месяца назад

have you seen the list of risks when taking ibuprofen?

@epiren 2 месяца назад

Hi, epidemiologist here and editor of History of Vaccines. All vaccines come with risks, but none of the "off-target" effects bandied about by anti-vaccine organizations and activists. The mRNA from the vaccine never touches our DNA, and it has a very hard time even getting inside the nucleus. As for long-term effects, with billions vaccinated in the last three years, we have millions of life-years of analysis. It's funny, because the same was said of the smallpox vaccine in the late 1700s and early 1800s. "It's going to turn you into a cow!" Then again with the rabies vaccine in the late 1800s. "It's going to make you act like a rabid dog!" And then again with polio. "It will paralyze you!" Every vaccine has brought its own misguided misinformation, while the actual side effects were far and few in between... And certainly much rarer than the effects of the diseases themselves. And when there were issues, the vaccines were quickly taken off the market. So, yeah, no "turbo cancer" (which is a great name for a metal band), no "died suddenly" (which should be the name of a computer brand), and no "off target" effects.

@ErebosGR 2 месяца назад

Ask your doctor, troll.

@punki2291 2 месяца назад

Risk about what? mRNA Covid vaccine? You get the risk sheet everytime when you go get the shot. It's safe and work as intended. It's the conclusion of a Cochrane review, it settle the scientific consensus. Really low chance of long term effect since it's not a drugs taken each day. It's impossible to cause more long term effect then what the covid-19 already does since the virus is more then the spike protein mRNA that it already contain. I talking as a Microbiology student