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How to calculate inbreeding from a pedigree chart 

Nikolay's Genetics Lessons
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Though there are computer programs, which will calculate the inbreeding coefficient automatically, based on pedigrees entered into a database, it is still handy to be able to calculate the inbreeding in less complicated pedigrees manually. Here is a short description on how to calculate the inbreeding coefficient from a pedigree by using the path coefficient method.

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5 окт 2015

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Комментарии : 120   
@ThiagoBenazziMaia
@ThiagoBenazziMaia 3 года назад
Thank you, 4 book pages of my book and I didnt understand. I watched 3 minutes of your video and now I got it. Thank you
@GeneticsLessons
@GeneticsLessons 3 года назад
Glad it helped!
@theyellowsparks
@theyellowsparks 5 лет назад
Thanks so much for this! My actual textbook doesn't seem to do a good job of showing examples... I needed help on the third example and you nailed it! Thanks!
@Lau_ma_lu
@Lau_ma_lu 5 лет назад
I´m very happy about finding your channel! You have helped me a lot already. Enjoy your day, thank you.
@fortunatembongo7200
@fortunatembongo7200 4 года назад
Thank you so much, I never thought I would understand this in 15 Minutes.
@dicungDon
@dicungDon 8 лет назад
Thank you very much for your explanation. It was clear and easy to understand :-D
@snigdhabanerjee5395
@snigdhabanerjee5395 5 лет назад
Thank you so much sir...ur all videos on imbreeding helped me a lot sir....
@moniabenadda9995
@moniabenadda9995 7 лет назад
Thank you so much u cant believe how much this helped me preparing for my finals ❤️❤️
@GeneticsLessons
@GeneticsLessons 7 лет назад
You are welcome! Thanks for watching.
@moniabenadda9995
@moniabenadda9995 7 лет назад
Nikolay's Genetics Lessons thank you
@hania.1220
@hania.1220 3 года назад
You are my saviour!!thank you so much. You explained it clearly and easily⚘
@GeneticsLessons
@GeneticsLessons 3 года назад
Glad it helped!
@mhackbardt
@mhackbardt 8 лет назад
Getting ready for the genetic counseling boards. thank you.
@erickaoctaviora696
@erickaoctaviora696 5 лет назад
Thank you so much! Its helped me a lot.
@suberuhamzaho546
@suberuhamzaho546 2 года назад
Thank you for this explanation! You sure are gna making me pass my finals👍🏾
@GeneticsLessons
@GeneticsLessons 2 года назад
Happy to help!
@nageshgorsera8569
@nageshgorsera8569 Месяц назад
thank you so much. it was easy to understand and after a bit of practice it was fast .
@anushkaathukorala_vonserendib
@anushkaathukorala_vonserendib 8 месяцев назад
One of the best videos. Explained very well and easy to understand it. Thanks a lot.
@GeneticsLessons
@GeneticsLessons 8 месяцев назад
I have many more videos on this topic with more complex examples.
@anushkaathukorala_vonserendib
@anushkaathukorala_vonserendib 8 месяцев назад
Yes I will watch but as someone who do not have scientific background it takes me sometime to understand it but I am really interested in COI. Can you please tell me do you explain " Weight's or Hardiman's COI?
@anushkaathukorala_vonserendib
@anushkaathukorala_vonserendib 8 месяцев назад
I am Breeding dogs and I see COI in the dogs pedigrees and that is why I want to learn about it. 😊 By the way in the second example should the answer be 1/64? Or am I wrong?
@tabbutabbu7075
@tabbutabbu7075 5 лет назад
Thanku very much sir.... Very easy trick to solve the problems....
@user-mm6ql9bz6s
@user-mm6ql9bz6s 8 месяцев назад
Thank you for your explanation. I'm able to solve my exercise related to pedigree analysis
@samrawitgebeyehu7648
@samrawitgebeyehu7648 Год назад
Thank you so much! Very clear description!!!
@GeneticsLessons
@GeneticsLessons Год назад
You're welcome!
@roro3793
@roro3793 6 лет назад
Thank you for your video I really enjoy learning about genetics. I have a question. Say I wanted to systematically check every individual recessive allele in an individual mouse. It's my understanding that you could use line breeding to increase the inbreeding coefficient. So breeding daughter back to father after 5 or more generations should bring you close to 100% coefficient. And at that point majority of the genes would be homozygous. Now say instead I made a cross between two unrelated mice. And then I took 5 daughters from that one pairing and bred them all back to the father. In theory the majority (near 100%) of the fathers alleles would be represented as homozygous across all grandchildren children but the inbreeding coefficient of each individual would only be 25%. Is this correct?
@GeneticsLessons
@GeneticsLessons 6 лет назад
These videos might help you: Simple Inbreeding Problem and Solution ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-WK-IVGvvDUU.html How to Find Inbreeding Coefficient (advanced problem) ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-BH07HbEkx6s.html
@swethaeswathe6144
@swethaeswathe6144 Год назад
Easily understood sir. . thank you sir 🙏keep doing..
@GeneticsLessons
@GeneticsLessons Год назад
Keep watching :-)
@anushkaathukorala_vonserendib
@anushkaathukorala_vonserendib 8 месяцев назад
This video is very useful to me as a breeder because I see COI in dogs pedigrees. ❤
@GeneticsLessons
@GeneticsLessons 8 месяцев назад
Do you know that I have a playlist - dog's breeding? Check it out.
@fanifariedah
@fanifariedah 6 лет назад
its easy to understand... thank you
@richardanaru5618
@richardanaru5618 28 дней назад
Thanks, you have enlightened me!
@karinkburns
@karinkburns 7 лет назад
Thank you. Ochin intereshna.
@GeneticsLessons
@GeneticsLessons 7 лет назад
You are welcome! Thanks for watching.
@sashikantaparida9763
@sashikantaparida9763 6 лет назад
Thank you sir.
@ewanentiege8931
@ewanentiege8931 3 года назад
Thanks very much. Well explained n simplified
@GeneticsLessons
@GeneticsLessons 3 года назад
Glad it helped
@russell1841
@russell1841 3 года назад
This is amazing. Thanks!
@GeneticsLessons
@GeneticsLessons 3 года назад
You're very welcome!
@esoheiyare9874
@esoheiyare9874 8 лет назад
Thank you very much
@fathimanajla5913
@fathimanajla5913 Год назад
Thank you Clear Explanation🙌
@GeneticsLessons
@GeneticsLessons Год назад
You are welcome
@bibliothekdeshorrors4084
@bibliothekdeshorrors4084 3 года назад
Great explanation. But I have a question. What if the common ancestor appears multiple times in the pedigree? For example: A appears on the fathers as the great grandfather but on mother's side as the father AND grea great grandfather. How would I count that? As one sire appears three times in a pedigree? Do I only take the closest one to the mother so the father?
@GeneticsLessons
@GeneticsLessons 3 года назад
I have many more examples of inbreeding - just search my channel.
@arias.p4355
@arias.p4355 3 года назад
Thank you very much...it was helpful 💖
@GeneticsLessons
@GeneticsLessons 3 года назад
You're welcome 😊
@Goodness_m-b4f
@Goodness_m-b4f 3 года назад
Thank you so much I finally understand this
@GeneticsLessons
@GeneticsLessons 3 года назад
Glad it helped!
@JB-01
@JB-01 Год назад
Thank you so much❤
@Shagunagarwal.
@Shagunagarwal. 3 года назад
Mannn u r the best
@XXTheDonkey
@XXTheDonkey 5 лет назад
I have a hw problem that starts with 2 separate lineages that eventually come together...and im very confused
@GeneticsLessons
@GeneticsLessons 5 лет назад
Check my playlists - I have tens of videos on this topic.
@saadisabrina2527
@saadisabrina2527 2 года назад
thanks so much really interessting
@GeneticsLessons
@GeneticsLessons 2 года назад
You are very welcome
@NourBellil-mb1hp
@NourBellil-mb1hp 3 месяца назад
Thank you so much !
@GeneticsLessons
@GeneticsLessons 3 месяца назад
Today, I am starting a new series of short videos debunking the 'Out of India' theory. ru-vid.comnv3YrBrGXdU
@CHEH_tf
@CHEH_tf 2 года назад
thx bro that's really useful
@GeneticsLessons
@GeneticsLessons 2 года назад
Glad it helped
@allblackeverything405
@allblackeverything405 2 года назад
Thank you so much
@GeneticsLessons
@GeneticsLessons 2 года назад
You're most welcome
@sheikhseerat7105
@sheikhseerat7105 5 лет назад
Helpful
@adityakhanijo7433
@adityakhanijo7433 3 года назад
Amazing!
@GeneticsLessons
@GeneticsLessons 3 года назад
Thanks!
@reemaxx2080
@reemaxx2080 6 лет назад
What does it mean when the numbers are bigger or lower? I mean in your example baby no2 is 1/32 and baby no3 is 1/16 . Dose it mean that baby no3 is inherting more from thier parents and ancestors ? Dose it have anything to do with passing and pushing harmful genetics?
@GeneticsLessons
@GeneticsLessons 6 лет назад
The bigger the number the bigger probability to inherit SAME allele . Say probability 1/16 is bigger than 1/32.
@alokneet
@alokneet 5 лет назад
@@GeneticsLessons Nicolay
@anthonylewis7812
@anthonylewis7812 3 года назад
thank you so much
@GeneticsLessons
@GeneticsLessons 3 года назад
You're welcome!
@pastat40
@pastat40 8 лет назад
What if some individual already was inbreeded? For example, what if individuals C and A in your third case were inbreeded. Lets say C had 0,5 and A had 0,25. What then?
@GeneticsLessons
@GeneticsLessons 8 лет назад
Than it would be reflected on inbreeding coefficient you have to multiply by this inbreeding numbers.
@sarahbelaid2897
@sarahbelaid2897 2 месяца назад
please in our lessons they did the same like you did but for exemple they did (1/2)6 but thery multiplie the result to 4 they said because they are 4 possibilities and i didnt understand when we mutuplie the inbreeding to a number in which case and how
@GeneticsLessons
@GeneticsLessons 2 месяца назад
Just watch my other videos in "inbreeding" playlist.
@sarahbelaid2897
@sarahbelaid2897 2 месяца назад
​@@GeneticsLessons which video please
@GeneticsLessons
@GeneticsLessons 2 месяца назад
I have many -any which have "inbreeding" in their name.
@nasserbenomar
@nasserbenomar Год назад
MAN ! ! thank you so much .. but sometimes its 1/2 and sometimes solid 1 .. so what the differences ? because this part a bit not clear
@GeneticsLessons
@GeneticsLessons Год назад
I have about 100 videos on this topic - just watch more videos and you will understand how it works.
@bonimaxwadenmark1
@bonimaxwadenmark1 5 лет назад
Am learning here
@user-cz3bf6cb4c
@user-cz3bf6cb4c 3 года назад
is this wright or handimans method?
@GeneticsLessons
@GeneticsLessons 11 месяцев назад
Watch my new video: How closely Adolf Hitler's Parents we related? ru-vid.com8kajiIuUwxw
@luizfilipepaiva2777
@luizfilipepaiva2777 Год назад
Can i use that to calculate inbreeding in humans..?
@GeneticsLessons
@GeneticsLessons Год назад
Yes.
@arisgolseen2693
@arisgolseen2693 4 года назад
What does it mean if "No common ancestry was found in 5 generations"?
@GeneticsLessons
@GeneticsLessons 4 года назад
Same ancestor from both mother and father side.
@walaaesseid9348
@walaaesseid9348 2 года назад
thank u
@GeneticsLessons
@GeneticsLessons 2 года назад
You're welcome!
@imaspinner76
@imaspinner76 Год назад
I realize this video is 7 years old. BUT I can't find the answer to my question. Though I haven't watched every coefficiency video you have. I breed goats and I am just learning coefficiency in breeding. Thank you by the way for making these videos! I have a diagram I'd love for you to look at. But no way to send it to you.
@GeneticsLessons
@GeneticsLessons Год назад
I have many more examples of inbreeding - which covers basically 90% of all cases. Please check the folder "inbreeding". You may send me a link to google doc - or write to my email which you can find in "about this channel".
@elijahavante2127
@elijahavante2127 5 лет назад
If offspring “I” produce offspring Male (M) and Female (F) and inbred produces offspring (O). What will be the inbreeding Coefficient of (O). Thank you awesome videos. Subscribing for more
@GeneticsLessons
@GeneticsLessons 9 месяцев назад
Watch my new video - How to live much longer: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-nW4ma5Y5liE.html
@pseudopetrus
@pseudopetrus Год назад
Now I know how I can marry my chickens!
@dauren.00
@dauren.00 2 года назад
Русский боженька, спасибо что вы это объяснили
@GeneticsLessons
@GeneticsLessons 2 года назад
Пожалуйста. У меня еще есть много видео на эту тему с более сложными примерами.
@KateeAngel
@KateeAngel 7 лет назад
Вам нужно работатт над произношением. Сильный русский акцент на английском - это что-то ужасное. По себе знаю) А видео очень информативны!
@GeneticsLessons
@GeneticsLessons 7 лет назад
Я работаю, у нас в университете полно иностранцев которые говорят с акцентом - и ничего ужасного..
@Yue_Jin
@Yue_Jin 6 лет назад
explaining how u get the 1/8 or 1/32 would be of great help.
@GeneticsLessons
@GeneticsLessons 6 лет назад
This is exactly what I do in this video.
@GeneticsLessons
@GeneticsLessons 6 лет назад
Here is another video on this topic: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-nePPKuwphn8.html
@pavelgrigorchuk5568
@pavelgrigorchuk5568 6 лет назад
А почему не на русском??
@GeneticsLessons
@GeneticsLessons 6 лет назад
Всетаки строительство 2000 церквей за последние 5 лет не прошло даром :-) Плоды не заставили себя долго ждать.
@alokneet
@alokneet 5 лет назад
Nicolay
@alokneet
@alokneet 5 лет назад
Nicoli
@dankobucanac4809
@dankobucanac4809 7 лет назад
Hello Nikolay, please check your Gmail inbox...
@GeneticsLessons
@GeneticsLessons 7 лет назад
Ok, I will take a look.
@dankobucanac4809
@dankobucanac4809 7 лет назад
Did you take a look?
@TonyTorzido
@TonyTorzido 5 лет назад
daddy nikolay
@omp199
@omp199 4 года назад
If Nikolay was your daddy, and you made a baby with him, what would the coefficient of inbreeding of that baby be?
@ninalilija7039
@ninalilija7039 2 года назад
how is 1/32 + 1/32 = 1/16??? please help
@GeneticsLessons
@GeneticsLessons 2 года назад
1/32 +1/32 = 2/32 = 1/16 same as 1/4+1/4=2/4 = 1/2
@GeneticsLessons
@GeneticsLessons 5 лет назад
Watch my new video: Adolf Hitler: Genetics vs Eugenics ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-D7cFfS3KfY0.html
@GeneticsLessons
@GeneticsLessons 3 года назад
New video: Pedigree vs. Arrow diagram (path analysis) ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-4HeLMpQra7Y.html
@GeneticsLessons
@GeneticsLessons 4 года назад
Watch my new video: "Inbreeding and Loss of heterozygosity explained" ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-5NYEJ1XbhQ4.html
@molekul8085
@molekul8085 4 года назад
your accent is so hard
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