Not a doctor but I’ve been on TPN for 6 years now and just curious about how it works. Good video! Also if anyone watching this has any questions for a long term TPN patient I’d be happy to answer
Thanks so much for a great tutorial! I have only discovered your series this afternoon and have already learnt so much! Would you consider a future learning session on albumin and the role of its measurement and when to supplement post-operatively please? Thanks again! :-)
Thanks , nice work But I think if 1gm of lipid equal 9kcal and with intralipid 10% the volume should be 700 ml . Please could you explain it if l'm wrong
Remember that to find the percentage of a substance in a solution it’s the amount of that substance divided by the total volume of the solution. So in this case if the total volume is 2440 then the amount of dextrose in this volume will be the percentage of the solution. I hope that is clear!
Thanks for the feedback and I’m sorry about the math error, I’m pumped that it was helpful for you! I’ll make a note in the description about the math. Good luck in your studies and if there is a topic you’d like to see let me know!
It’s such a great and vexing question and the answer seems to be related to dietary omega six increasing the circulation of arachidonic acid which is proinflammatory. Check out this abstract… Inflammation is a normal process that is part of host defence and tissue healing. However, excessive or unresolved inflammation can lead to uncontrolled tissue damage, pathology and disease. In humans on a Western diet, the omega-6 polyunsaturated fatty acid arachidonic acid (ARA) makes a significant contribution to the fatty acids present in the membrane phospholipids of cells involved in inflammation. ARA is a precursor to a number of potent pro-inflammatory mediators including well described prostaglandins and leukotrienes, which has led to the development of anti-inflammatory pharmaceuticals that target the ARA pathway to successfully control inflammation. Hence, it is commonly believed that increasing dietary intake of the omega-6 fatty acids ARA or its precursor linoleic acid (LA) will increase inflammation. pubmed.ncbi.nlm.nih.gov/29610056/
I talk about that, there are different energy requirements based on the severity of illness and the respiratory quotient, the patient may need 40kg/day, also important to recognize the possibility of over feeding