I Grew Real Spider Silk Using Yeast 

Technically making spiders out of beer.

@@greenaum technically making something not very beer-like out of a yeast variant with spider DNA spliced into it

We have more realistic goals, then?

@@Butter-Milk who’s we you aren’t a mad scientist

mado scientisto in animes: El Psy Congroo.

😭

Yup I'm a total Chad ,don't understand shit but it's cool

@@hardanalljr.3138 Are you build as a Chad as well? Cause, cool.

It's being worked on, but we're trying to commercialize it so can't share updates yet

@@thethoughtemporiumthanks, I was wondering why it wasn’t being continued

This had made so damn happy. I thought this project was long forgotten

​​@@thethoughtemporiumI would think that this would get funding fairly easily due to how strong spider silk is and the amazing utility we could get out of growable high strength building materials, and something I just thought of while watching the video explaining the structure, spider silk is a fabricy version of reinforced concrete.

@@thethoughtemporiumlike a suburban superhero???

X2

love your videos

Anton came out of the Solar System to check out this amazingness!!!

hello wonderful person

LOL

Because he's one of the good guys, not subverting science for the highest bidder. He's one of those scientists that need crowdfunding the most, to keep him free of the likes of bigCorpo who'd put a life patent latch on it and shut it for good.

Haha yeah it's awesome, right? 🍄

Right? I remember watching Ripley's believe it or not as a child and one of the guys featured there had made a really durable, strong suit out of bunch of materials including spider silk he milked out of actual spiders and since then I wondered about the possibilities of creating some super hero costume out of spider silk. It's truly wonderful that people are coming together to make education easily accesible and likely creating future scientists.

Same here.

Even though spider sill is a real good material it also get most of its strength through how the spider twists the silk together

Don’t worry once I have money I’ll make them

This part you probably already knew, but using IRL web shooters with absolutely be one of the most dangerous things you've ever done or did anyone could realistically ever do, but spider silk binded with carbon nano tubes. Could absolutely if made correctly hold the weight of multiple humans, I don't think you're doing Oh that the web shooter could do in a little canister. That's the size of your pinky but in especially designed flat pack tank that goes over your stomach, now we're talking. Because of how easy it would be to vary the properties of the silk when you produce it, depending on which particular strand of genes you use, everything you see Spider-Man doing with webs would be at least theoretically possible to do with at least a version of what is demonstrated in this video

This is basically me trying to understand how kars survived falling into lava, but with *Spiders*

Hell yea😂😂😂

I dont even understand algebra let alone this. But the idea is interesting enough for me.

I saw a post online about the iron snail a couple of days ago, so I'm basically an expert

@@v1298 yes xD

Yes

Yes

Yes

Yes

Yes

I really don't get what you're saying, but I'm happy that someone's happy in this world

Makar Ismaile Adnan He’s happy that the creator of this video is so transparent with his process and so willing to share his results. Plus, the fact that this content is distributed for free.

This is really “the future” it’s the transitional period between the past and the future. Right now everything cutting edge is being discovered and all these cool products will most likely be widely available by the time we’re all dead or really old.

Is it just me or is it crazy that they can Patten certain animal genes, that's absolutely some dystopian stuff right there.

well, we didn't have git back then

@@otheraccount5252 NO SHIT SHERLOCK

@@otheraccount5252 wow really

@@otheraccount5252 Really???? I thought github was like hundreds of years old omg thank you

@@Josuh the whacky part is that this sentence might someday be true.

because of prions

I mean he's kinda playing God so yes it is menacing

You WHAT

i can now become spiderman

*He's becoming a Spider-Man villain*

Now I want a “hold my spider beer” shirt.

Hold my Southern Black-Widow in Ethanol*

Ｏ－Ｏ　ＷＨＡＴ　ＴＨＥ　ＦＵＣＫ

I wonder what spider beer taste like

Spider Cider - Made with real spiders

advanced homeman

Lmao when is the Hot Glue Web shooter swinging video coming up?

Joel Creates I wanna say same, _but..._ I don't know calculus yet (among many _many_ other things that would likely leave me a bumbling fool in most any *_real_* lab) 😞.

@@ivoryas1696 I was referencing the Spider-Man meme, since I recently built a hot glue web shooter. Technically I'm a musician...

@Joel Creates Neato! I'll check it out. -Also, I'm somewhat of a musician myself!-

Me too - my latest project is observing the time it takes to cook a '3 minute egg'.

IKR dis crap is insane

Where’s Oscorp when you need’em

Patreon

@@theunknowngamer5477 You know those movies are fake right lol

@@fuckdeadfaces for now...

Capitalism go brrrrr

If someone could patent the sun they would

Let's not encourage them

@@Hoshimaru57 its called nuclear fusion!

Can someone explain how anyone could hold a patent to a gene found in spiders to begin with?

Me too. Great videos from the both of you.

Are you okay

This comment prompted me to give the video an instant thumbs up

I will combine Yeast and Starlite and rule the World!

Now he just needs little wrist siphons.

Hippity hoppity your genes are my property

Surely nothing can go wrong when mankind tampers with nature... GMO is scary stuff

@@nightelfmohawk9821 Well, I mean, spiders are scary too, I guess.

@@nightelfmohawk9821 And chihuahuas

@@nightelfmohawk9821 k but, how is farming spider silk dangerous

I'm wondering why I've been searching for a Spiderman comment. Thank you

Same as tony, with a box of scraps but in a slightly nicer apartment.

did it in high school too ..,like how

The excuse is that Peter feels the necessity of making spider silk so that’s why he can make it? It’s really weird if I’m honest

Well Toby McGuire his webs were natural Andrew Garfields were stolen from oscorp and Tom Holland I don’t know but I’m pretty sure in the comics (I’ve never read them so this might be wrong) the spider bite gave him the formula composition and he was able to buy the products to make it

"I love it so much, I can't seem to take it off!"

The yellow ones are edible, but don't try the blue ones

Only $9,999.00. 😄🤑

@@GuilhermeCargnelutti I'm gonna eat the blue one

the colors wouldn't even need to be dyed. they could actually be from the silk it's self

But my tenure!

A lot more. Get ready for an influx of scientists making RU-vid channels.

'With great power, comes great responsibility.

@@blackjoker2345 REALLY great profit margins

I am a teenager, but I am totally amazed how advanced and well understood biochemistry is.

I am an idiot, but I am totally amazed how advanced and well understood biochemistry is.

@@themblue8236 lmaoo

I am a biomolecule, but I am totally amazed how advanced and well understood I am

@@mastershooter64 you win this thread

isn't all beer made out of yeast though?

Hold my spider beer*

Hold my test tubes

@@bovanshi6564 Spiderbeer Spiderbeer... Does everything a spider can... Make a web? Anytime... Look out... Here comes the Spiderbeer...

Hold my beer but don't drink it. It's full of spider silk and tastes terrible.

Remember what he said tho

Brian thats what we get in a a country run by corporations

Huh I've been learning that sht to get marks from the 9th Grade and now I can use that knowledge to brag to a random guy on the internet because I know it and he doesn't [I now realize that's all that information is every going to be useful for]

Lmao imagine existing and the big companies are like: "your genes are mine!"

Kinda reminds me of the tree that legally owns both itself and the land around it.

I know right, it seems that there would be some legal trouble with whoever made the patent and the original genetic designer of the animals, or would the actual spider be the patent holder of the silk since it originally created it, either way it doesn't exactly seem legal.

Thank you so much! Once I've got some fibers made, I'd be happy to send them over for you to play around with if you'd like

Here's an idea: Electron Microscopy videos of all the mineralised silks!

@@thethoughtemporium Maybe Ben could X-ray diffract image them, or run them through a mass-spec, or the Electron mic, or ALL THREE! amazing work, there should be a "RU-vid science medal" or something.

i think we are on the cusp of a revolution ... who needs elsevier , springer or iEEE these dudes together with a couple other sci-tubers are doing more cutting edge research than many well funded snob colleges.

@@thethoughtemporium Growing fibers is cool - But I would reccoment that you try mixing some into a Kombucha brew and make a SCOBY - you'll get nanocellulose tied to fibroin... it might be revolutionarily strong. Use weak/white tea if possible, and you can actually just use mineral supplements in sugar water for a "cleaner" SCOBY. Also, that way, the yeast/bacteria make the sheet for you, and you don't have to worry about the fiber weaving process.

I would be interested in where LOTUS silk falls on the graph at 10:10

Next next project: spiders that make beer

@@sleezymechanic next next next project:yeast that makes dimonds

@@notajalapeno4442 next next next next project: yeast that make any material

next project: watch youtube and feel like I have done something

next project: clean kitchen

that's exactly what was going on in my mind watching this video

Yep. I feel totally the same. I want to know more.

Same here... just... wow...

You've found your resolve my friend.

IKR it's like a game xD. You can just add whatever you want??? Lmao sign me up!

4 mins in “what is he even talking about” 20 mins in “of course the pPCI9k needs to be linearized with a restriction enzyme! You can’t have those DNA rings, duh!!!”

it sounds like foreign language

I interpreted this as an informal video-essay type of report on his findings, truly fascinating, yet extremely confusing to people without bio-majors, like me ;)

ShamelessDuck like you can print DNA?! that is kinda crazy, just humans writing their very own DNA designed specifically to hijack in this example yeast. I searched DNA printing on google and you can apparently make custom creatures with it, which is insane

@@tormodhag6824 I dream of future when we will use GMOs legally in our everyday life without it being marketed as "non-GMO" and without this whole stigma around it.

Ikr And I love how the God-Tier RU-vidrs all know each other XD Applied-"I built a scanning electron microscope from scratch in my shop"-Science and Tech-"I made a nanostructure imprinted chocolate bar diffraction grating"-Ingredients both commented here alongside us! XD

FAVIAX Delatorre hol up

Indeed it is, my friend

@FAVIAX Delatorre 😤😤😤ಠ‿ಠ

@FAVIAX Delatorre That's f**ked up.

FAVIAX Delatorre get out.

Secret Santa gone hardcore

@@minermortal1997 now THATS what I call an office party!

...

I literally lost it when he said that

I will make my own DNA with hookers and blackjack

@@ProctasisLimerna and without the N.A.T.O!

@@ProctasisLimerna this sounds like a Cave Johnson quote.

so smooth

There's something silky going on......

wait till he can print his own DNA without a company

Can't wait for the video on "spidey-sense".

@@suicideiscla55ic The real question: how would you go about achieving it?

Get bit by every spider

Spiderboiii

@@0th_Law Tarantula DNA? They use their hair to detect changes in the air. Spidey Sense was meant more to represent an invisible web of sorts, though I've also seen it as representing the 8 eyes spiders have though they actually have really bad eyesight. But by coincidence Tarantulas already have a spidey sense going for them.

Same

First- Oh fuck

Dito

Right lol

Thanks!!

hey Tech Ingredients I love your channel too

@@communist754 lol

@@thethoughtemporium You should collab with NileRed

@@communist754 why would he collab with someone who no one knows xD he doesnt even know if you know anything about the topic

Nice

Lol, he's not wrong.

I’m imagining a plant just biting a giant chunk out of the sun

@@joshuanetanel9174 Of course, the kale kills.

Soylent green is people too.

lol, same, I'm just curious to see what emerges in the next 25 years from him & this field

i would love to see a plant eating the sun

it does add another meaning to "spider can", right?

Yeah, i was especting that. But i'm more interested in the practical use of spider silk, cause it's resistance is legendary.

@@kiriki4558 I was referring to a Beer-CAN full of silk. (assuming you are replying to my comment that is) The practical applications are a no brainer. 10 years ago i would have shelved this under sci-fi, jet here you are actually doing it. btw, the biomineralisation feature sounds amazing. I cant even imagine what properties spider silk bonded to carbon nanotubes would have, but i'm sure it would get you out of a sticky situation, or create them for that matter.

KRIEGER!

The first entity to isolate a particular gene gets to file a patent on it under the current biotech regs. Leads to some very undesirable possibilities. It's one reason to be suspicious of those 'we'll analyze your DNA to determine your ancestry/risks' things, because it's potentially a mechanism for someone to gain a monopoly on all commercial use of one of your genes for the next few decades.

capitalism

@@wacesferpit That's the more succinct explanation yeah.

@@Kharmitas ... and then (after the 20 years) your own personal gene is open to the public to use as they see fit.

@@eichenbrain6170 Twenty years after a corporation had the opportunity to raise the price of whatever treatment it may have turned out to be useful for to the point that thousands of potential beneficiaries went past the point of no return without ever having the capability to pay for the treatment.

I understood all of those words separately and am proud of myself for that.

If this is true, on top of making it a commercial clothing or building material, this guy could be looking at a Nobel.

I think that could do a lot more than just repairing turbines

While it could do that, would it not also coat the ocean floor in carbon doped silk?

@@thecallankids4718that I’d assume degrades faster than thousands of years

It's actually decently intuitive. If the yeast produces a protein with the ability to bind graphene, then the graphene oxide will naturally coagulate around the proteins, and therefore the yeast, because it is being bound to the proteins.

@@0th_Law hUh 😐

@@WhatTopic2004 If you want, I can clarify stuff for you; just tell me what doesn't make sense. (This is assuming that you mean that what I wrote didn't make sense. If that isn't the case, then never mind.)

@@0th_Law you said some smart stuff but I think this comment is meant to be a joke and you added some smart stuff to it, so idk

@@arrowsaurus7561 You're going to have to be more specific than that. Otherwise, the answer will probably just be something like "Cell Signaling" or "Conformational Changes"

It's often that insularity that convinces people to take up and believe pseudoscience and eventually erode trust in science and data

You call fax I mean we are all forced so deep into the thought that science is all boring stuff on paper but no it's fun aswell like artificial meat or aerogel and theories like our universe isn't finite and it's a loop from one point to another or that aerogel can be used in rockets as insulators.

I remember how in the action lab they mentioned that the structural strength of steel regarding tensile strength is in the gigapascals. Even specialized steel it's not like it's 10,000 times which spider silk can handle or whatever. Who knows how many creatures have a shell made out of nacre oh, it's tensile strength depending on the species is 170 gigapascals, even if one gigapascal is 2 megapascals this is still a whole lot more than steel. The trouble is this bad boy takes 170 gigapascals to bend, or is that bend it to a point that it will no longer Bend back. Either way that is a whole lot. I did the conversion for both of those, 170 gigapascals is more than 24 million pounds per square inch, and 70 is more than ten million. I did the conversion for both, I checked the conversion multiple times for the tensile strength. I'm pretty sure that I did the 70 kg pascals correctly given how much of it was copying and pasting, and using an online calculator. This is far beyond Steel. Now this is so strong because of the way that it is aligned, according to Google it's like more than 300 or something times stronger than the material it's made out of. So imagine graphene was in the structure that this material is in. And I'm not talking about the structure of which its atoms are aligned. This bad boy is made in a structure of pretty much interlocking tiles, so imagine this was what was going on with a flat thing of the functionally two-dimensional graphene oh, that bad boy would be incredible however graphene is very flexible so this might defeat the purpose. However something tells me that if the graphene were to be bio mineralized to be interwoven with the nacre be beneficial.

¿Is that that a Raimi reference?

@@estebancino5426 no.

@@cleosvoyage9191 yes - the quote is from sam raimi's spiderman movies

I studied abt genetic engineering

@@ytshorts9609 I studied the entire ABC of English alphabet and got it all memorised now! Pretty cool, huh? 😎