Thank you for providing information and stimulating more conversation about osteoporosis. Those of us who suffer from it are ridiculously under-served and often outright dismissed. I appreciate you!
This is interesting, I’ve been taking this for 20 years, to replace the hormones we had been taking for menopause, hot flashes that were causing heart problems. I never got a good explanation of the side effects of raloxafene. Over time I got an explanation of the breast cancer help . Over the last 40 years all 3 of my sisters had breast cancer and have died. They never took this drug. I’m 77 years old and have never had any problems taking the drug. I get an annual mammogram and have never had any symptoms of breast cancer, I always mention my family history of breast cancer. I have had vaginal cancer, squamous cell stage 3. Treated like cervical cancer. No surgery but I did have radiation, chemotherapy, brachytherapy. Now have follow up scans once a year. So far all good. Feel good. I thought this might be something I should share with you. Thanks for sharing your research.
Hi Janice. thank you for sharing your experiences. Question, did your sisters take oral or topical estrogen and or progesterone? Family have BRCA gene? Thank you.
@@tammywheeler7463 No to both , they were diagnosed in their 40’s in the 1980’s. One died within 2 years, second one died age 69. My third sister was diagnosed at 75 yrs. and did not die of breast cancer, she died of a stroke at 80 years old.
As a breast cancer survivor, and otherwise healthy woman in my sixties, my GP is more than happy to keep up my prescription to Tamoxifen, which I understand has similar properties to Relaxofene, as an "off label" treatment for my early stage osteoporosis, even though my oncologist couldn't care less (his words) if I take it or not. My GP is young, smart as a whip, and totally on top of all recent research, unlike a few GPs I've had in the past. In Australia, we benefit from what is called a "care plan", which is free referral to preventative modalities such as physiotherapy, exercise physiologists, etc. The government worked out it is cheaper for the health system to give lifesaving prevention than to treat end stage disease in hospital. Exercise, sunshine, supplements in moderation, clean eating - that's my strategy for this condition.
Thank you for sharing. The BMD improvement in Tamoxifen is not as strong as Raloxifene BUT what's right for one patient is going depend on multiple variables. Some protection is better than none!
I had stage 2a estrogen sensitive breast cancer 5 years ago at age 55. I underwent a double mastectomy without reconstruction and was put on anastrazole. At that time I was diagnosed with osteopenia. I took control of my life, lost 130 pounds with gastric bypass surgery, began a heavy weightlifting/muscle building program, cleaned up my diet, began taking calcium citrate and d3 three times a day. My BMD slipped into osteoporosis -2.7 at the left hip. I received a Reclast infusion and experienced severe bone pain which lasted almost a full month. The first 4 or 5 days I could hardly move, the pain was the worst I had ever had in my life. After doing more research i have begun using some SARMs and peptides including RAD140, MK677, TB500 and BPC157. My BMD improved to -2.5. It has been a year and a half since the infusion and they contacted me to get another - I refused. I told them about the peptides/Sarms, but they had never heard of them, the credited the Reclast with the improvement, and I told them I would like to try raloxifene to replace the anastrazole and reclast and they agreed. I am 60 now, 18% body fat, 135lbs, 5'3". I lift heavy 4 days per week and work a physically strenuous job that involves a lot of lifting, carrying, bending, squatting and walking. I tan in a bed once a week for the natural D. So far, so good....no sides from adding the raloxifene and dumping the anastrazole. Since you are more familiar with peptides and hormone manipulation, what do you think of my current program and is there anything you would consider adding or removing from my current regime?
@@lisasmith2016 I think WOW! Great job thinking outside the box. I'd want to know more about biomarkers and nutrient levels. You remain at risk because of gastric bypass but this can be managed.
Thankyou. I was waiting for this one on Raloxifene. My endocrinologist recommended it and I complied. No cramps, hot flashes; very uneventful and I'm glad.
Thank you for making this video. It does help to clear up some of the confusion around this particular drug. Much appreciated! Still very much on the fence about taking it though. Trying the Algae-Cal route for now. 🤞🏻
I started taking this drug two years ago and reversed osteoporosis in both hips and went up 6 percent in spine Spine is still in osteoporosis but moving in right direction I also did alot of one leg workouts for my hips My cholesterol and triglycerides dropped to normal range Forced into menopause from breast cancer treatment so extremely pleased with results so far I also read a study that you see the full results of raloxifene in 4 years
I'm a physician (age 69) and when I found out I had osteoporosis by having a vertebral fracture, I initially ordered some of this, as I didn't want to take bisphosphonates, and I didn't want to just sit around waiting to see an endocrinologist (3 month wait). I then stopped it because I wanted to go on HRT instead. The fact that I took it was good, because that means that post-fracture, and post trying an "initial" drug, the endocrinologist is going to get me Tymlos, which I now qualify for. She ruled out hypercalciuria, and we're still awaiting the results of testing for mutations, related to osteogenesis imperfecta as a broad class. I think the reason osteoporosis is an "orphan" disease, is because it's pretty complicated to understand and manage. I appreciate all you are doing to help enlighten sufferers, as you do tend to feel abandoned when you get diagnosed.
Hi Dr Doug I have been listening to your excellent informative shows for a long time. Can you please talk more specifically about HRT for post menopausal women. I am 70.
I have been on Raloxifene for 7-10 years with zero side effects. No history of cancer ( other than basal cell skin cancer) nor blood clots. I recently had an appointment with an ob/gyn PA. She mentioned it might be time to go on a "drug holiday" and make that decision at my next Dexa scan ( in 2 months). I asked what was the max number of years it was recommended I limit it's use. She gave a standard answer of " 5 years for osteoporosis medications" . Have you come across any studies that looked at length of time patients remained on this medication? I very much appreciate all the information you provide . I am working my way through the masterclass videos and workbook.
Great question! Checkout our health span nation if you have not yet, you get exclusive access to me and a community of people pursuing health and longevity. These are things that we discuss in there and it allows us to go into detail rather than doing short chats through this platform. You can find more information here --> www.drdouglucas.com/healthspan
Great question! Checkout our health span nation if you have not yet, you get exclusive access to me and a community of people pursuing health and longevity. These are things that we discuss in there and it allows us to go into detail rather than doing short chats through this platform. You can find more information here --> www.drdouglucas.com/healthspan
I took Bisphosphonates after breast cancer. It was an awful experience. The drug makes your bones ache and it makes them brittle. Bones should be spongy. I am now facing -2.5 osteoporosis and hips and spine and I’m hoping Evista will be an alternative my PC Dr will consider. I lift weights, walk, eat healthy and fast. I’m a healthy weight so the only factor that seems to be off is my hormones due to a hysterectomy in my 30s and being 70 yo. Is this drug something that can help me?
Very informative video. Thank you. So given the risk of blood clots is it not recommended for people with Factor V Leiden? Im currently on transdermal HRT.
Hi! This is going to be different per person. Unfortunately I cannot provide recommendations through this platform and without knowing more information. If you would like to learn more about our program and speak with a specialist you may schedule a discovery call here --> www.optimalbonehealth.com/membership"
I have GERD which means I cannot take bisphosphonates. I followed the Lilly studies and went to my doctor for a prescription the minute Evista was approved in 1997. It took 17 years to restore my bones to normal density without any side effects. Switching to Prolia is out of the question for me because I'm quite vain about my teeth and am mortified at the thought of jaw osteonecrosis. I also had a friend whose leg broke under her while she was doing nothing more than unlocking her car door; she was old, and never fully recovered. She took Prolia. The only thing about raloxifene that is annoying is that I'm off it after a good DEXA -- then I'm back on it again after the next DEXA 2 years later. I'm not happy with the yo-yo effect on my bone density, so I'll ask my internist if I can just stay on it forever. I enjoy a genetic anomaly that protects me from clots and stroke.
Thank you for sharing this! Checkout our next free bone foundations masterclass session if you have not attended one before, this could be beneficial to you. You can find details at this link --> www.optimalbonehealth.com/bone-foundations-master-class
Would you provide a link or video title for the video on Estrogen you referred us to within this video? Thanks! Edit: I think I found it from 2 weeks ago: Hormone Replacement, Estrogen and Osteoporosis: Fear and Hope.
Great question! Checkout our health span nation if you have not yet, you get exclusive access to me and a community of people pursuing health and longevity. These are things that we discuss in there and it allows us to go into detail rather than doing short chats through this platform. You can find more information here --> www.drdouglucas.com/healthspan
I don’t remember you telling when you would use this drug. My lower spine is in -4.2 range,other areas -1.9 to-1.2 so spine worse than hips. I took one dose of this years ago when it first came out and quit because of horrible hot flashes. Obviously Algaecal has not stopped progression. My gp wants me to try Evista again. I don’t want to.
I’m 82 in November. I went to my regular doctor..and I told him I have a pain in my not hip… Lower ..more like on my bottom hight up ..I can touch it and massage it..and it slowly was a pain in my side…and until I turn 80 all was well than it progresse …..slowly I could walk 30 minutes but eventually the pain got down my back my legs and the pain was so bad I had to sit down .I had all the test MOI ..screening ..blood test…the result is I have osteoporosis..but it is not my bone that hurt it’s that muscle in my butt ..I don’t want to take strong pain killer "so I suffer ..I now have an electric chair to go shopping and look around the town it,s nearly summer 🌺 I will go to the beach but that pain stay there all day and because of it I’m loosing my legs..is anyone else has something like this ?
I’m sorry you are suffering like this. Consider looking for an orthopedic surgeon, physical therapist or massage therapist that can identify the cause of pain.
Checkout our masterclass or health span nation if you have not. We are able answer more specific questions through those platforms. Links for both of those are in the video description :)
Since Prolia keeps the osteoclasts from making new bone, are supplements and weight bearing exercise valid for building bone at all? Or does Prolia nullify my exercise, meat forward diet and vitamin MK7?
Yes, we are 100% virtual so we can see anyone in any place :) If you are interested you can schedule a discovery call here --> www.optimalbonehealth.com/schedule
Unfortunately there aren't many. We are working with the company in Italy to determine if there are more but the three we know of are in NJ and two in NC. Dr. Bush and Dr. Lewin in Asheville. I don't technically have one but we work with Dr. Lewin to get our patients into his practice.
Great question! Short answer is, we don’t know. There are no long term data on long term use but women are prescribed this drug for long term use. I prefer to use estrogen whenever possible for this reason. Additionally we have found that raloxifene can cause more side effects than estrogen.
Hi there, This drug belongs to a class of drugs called aromatase inhibitors. They block conversion and production of estrogen and will result in lower estrogen levels.
So, as a breast cancer survivor, (post menopausal)currently on AI, then I could take (add) Evista? I do have osteoporosis (early) and had to stop tamoxifen when my cancer came back....???
@@Dr_DougLucas thanks, I've definitely reached out! Actually curious about "how" evista works to help understand if this would be an option for those of us (unfortunately many of us) on AI's
If you would like to learn more about it, checkout our health span nation. We discuss things like this, you get exclusive access to me and a community of people pursuing health and longevity. You can find more information here --> www.drdouglucas.com/healthspan
