Great lecture, but I'd like to make a correction: IPEX syndrome primarily involves a deficiency in peripheral tolerance, rather than central tolerance. This distinction arises because, although regulatory T cells (Tregs) originate and are selected in the thymus, their critical function in maintaining tolerance occurs in the peripheral tissues. Their role in controlling and suppressing immune responses to self and non-self antigens is crucial in preventing autoimmunity, situating the dysfunction seen in IPEX within the realm of peripheral tolerance mechanisms
Great lecture. It would b great if you could repeat the student questions prior to giving the expert answer because the mic does not pick up well and that way we could feel like part of the lecture.😊
I remember reading 'Rapid Interpretation of EKG's' where you were tested on what you should have learned as you go through the text. I notice you use this style in class and I think it is a very good approach. Reinforcing short term memory. I'm not a teacher so I don't know if it is the best way to learn but it helped me. Mike in Oregon
