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Intolerant to Folate? Folic Acid Causes Adverse Reactions in Undermethylated Depressed Persons 

Walsh Research Institute
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Dr. Walsh explains why undermethylated depressed (low serotonin) persons respond poorly to all forms of folic acid.
To learn more, visit www.walshinstitute.org.

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7 сен 2015

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Комментарии : 116   
@ilianainc
@ilianainc Год назад
This video helped me SOLVE my insomnia after 1.5 years and multiple doctors. I had low seratonin and had been taking a folic acid supplement. The minute I stopped it I was able to sleep again. Thank you thank you
@amgnico
@amgnico 6 месяцев назад
How long did it take? took 200mcg ACTIVE folic acid and my anxiety is sky high. I stopped now after 30days
@hargrovegeneralgoods
@hargrovegeneralgoods 4 месяца назад
My mom experienced the same, it was almost immediate for her.
@hargrovegeneralgoods
@hargrovegeneralgoods 4 месяца назад
​@amgnico if you haven't removed food sources for folic acid such as conventional store bought breads and cereals you are only half way there.
@janetusa5129
@janetusa5129 6 лет назад
I've been taking Homocysteine Supreme by Designs for Health for years not feeling better but being compliant and now 17 yrs after they found out about this intolerance to folates, I find out about it. Thank God I finally did.
@bc9086
@bc9086 2 года назад
What can we take since methylfolate causes depression symptoms? I can’t seem to find the answer. When I become undermethylated I feel so sick but when I take methylated B’s I feel amazing for an hour then the depression sets in
@kineticstarz347
@kineticstarz347 Год назад
@@bc9086 I believe Walsh recommends SAMe / Methionine for undermethlators intolerant to Folate
@CeptemberDane
@CeptemberDane 2 месяца назад
this man saved my life
@baconlatte
@baconlatte 7 лет назад
This seems critically important. Seems everyone says, if you have methylation issues, take Folate.
@SufyMusic
@SufyMusic 6 лет назад
its great if you are overmethylated
@LuvBugBlaqkHart
@LuvBugBlaqkHart 3 года назад
@@SufyMusic yeah lol and not so great if you're undermethylated 😅
@jpfitness2242
@jpfitness2242 3 года назад
I'm undermethylated but folate doesn't bother me. I, however have poor tolerance for sulfur. It causes brain fog and depression for me.
@saintjabroni
@saintjabroni 2 года назад
@@LuvBugBlaqkHart Why would taking folate to help/aid to gain more methylation be bad if you’re naturally UNDER methylated? I must be having it all wrong…(??)
@saintjabroni
@saintjabroni 2 года назад
Also, don’t say it as “methylation issues”… That does NOT specify which group of methylation, at fucking all.
@lisathebeautician6489
@lisathebeautician6489 5 лет назад
Is folate a water soluble vitamin that would be excreted if the body doesn’t need it?
@katiie7
@katiie7 3 года назад
Does thyroid hormone speed up methylation?
@purrrrguy
@purrrrguy 5 лет назад
Thanks. This is me.
@harrietbeatrice7857
@harrietbeatrice7857 7 лет назад
Hi there Dr. Walsh, firstly, thank you for your amazing research. I'm struggling to find anybody else doing the research you are, so I can't thank you enough for your work. Basically, I am really, really confused about what to do. I can't afford the private tests for histamine, genes, all that stuff, and they definately do not do them on the public health service. I was born Vegan, so I guess I naturally eat loads of folate. I don't know if I'm an undermethylator or an over, but recently I've been taking metafolin with MB12 (been taking that for months) and I seem to feel worse and worse. Yet everybody seems to say folate is essential for methylation. All I can say is that the things that really seem to improve my mood, turmeric, caffeine, Inositol, are all methyl donors. What do I do? Do I cut out all forms of folate? Including metafolin? And food? For ever? Or do I need a little bit for methylation, so maybe just from food? I'd be grateful for your advice. Thanks.
@SufyMusic
@SufyMusic 6 лет назад
hi harriet you could be overmethylator or under
@pfeiffeerr4024
@pfeiffeerr4024 3 года назад
probably you are overmethylator, same affects happen to me while ı was first starting the use mb12 but with folic acid not metafolin.I think ı m overmethylator too and overmethylators can have excess copper level because of the low histamine and some gene defects.You should check on your copper level.İt might be your secret and normalized enemy.
@LuvBugBlaqkHart
@LuvBugBlaqkHart 3 года назад
People with issues with taking folates are usually undermethylators. I'm undermethylated. I now have stopped my methylfolate supplement and I'm doing better. Not 100% but I do notice a difference
@JP-hv9du
@JP-hv9du 2 года назад
I dont really understand what he's saying. So should I take folates or not? What will help if I'm undermethalated like he says with bad anxiety?
@karenfunseth2162
@karenfunseth2162 11 месяцев назад
Agreed. What to do if I can't tolerate folates?
@thesilverone94
@thesilverone94 2 месяца назад
Hi JP, did you ever manage to get on top of your methylation issue? Thank you
@freedomwarrior5087
@freedomwarrior5087 11 месяцев назад
I wonder if TMG could help?
@PhonicswithMrsBerg
@PhonicswithMrsBerg 7 лет назад
So, UMs should avoid all folate, not just synthetic folic acid? What do you recommend for pregnant women?
@saintjabroni
@saintjabroni 2 года назад
Any update on this matter? Particularly the former.
@joriwilkinson
@joriwilkinson 4 месяца назад
I don’t feel good when I take prenatals for very long so I just make sure to get it from whole foods and I do much better. I am pregnant with my second baby now. Eggs, oranges and kiwis are my favorites
@Guyhakverdi
@Guyhakverdi 2 года назад
So, what do these people take ?
@jeffreyconnor9769
@jeffreyconnor9769 10 месяцев назад
You have to get Folate from unprocessed food and AVOID Folic Acid from processed foods and multivitamin supplements. Check labels avoid folic acid if you value your health.
@chastings.0543
@chastings.0543 7 месяцев назад
​@@jeffreyconnor9769you can also supplement with methylfolate it helps a LOT
@lenoredavi6137
@lenoredavi6137 3 месяца назад
And avoid bakery products with added folate. Basically, eat loads of green leafy veg every day, and fresh unprocessed protein. .... nothing out of a packet.
@marcdellorusso180
@marcdellorusso180 2 месяца назад
What about methylfolate found in supplements with b12 and b6? I’m guessing people with OCD should avoid them.
@RachelWilliams-hn1fc
@RachelWilliams-hn1fc 6 месяцев назад
Hi! Do you have a solution to counteract severe brain fog and depression brought on by taking folinic acid? I stopped taking over a month ago and am still having symptoms. Thank you!
@bwealthyrb123
@bwealthyrb123 6 месяцев назад
I recommend you watch Joe Rogan and Gary Brecka #2060
@joriwilkinson
@joriwilkinson 4 месяца назад
Make sure you aren’t eating and pasta, bread or packaged food with folic acid added to it. Most things that come in a package especially non organic contain added folic acid.
@jennifernicholls9360
@jennifernicholls9360 4 года назад
My pyschiatrist who trained with Dr Walsh has put me on Folinic acid. Am I am high in histamine, am C677T heterozygous. And apparently my folic acid blood levels need increasing. Feeling a bit confused
@i.ehrenfest349
@i.ehrenfest349 4 года назад
Well this seems to be a fairly recent finding. You might show this video to the shrink.
@ollymounara605
@ollymounara605 3 года назад
High histamine has more causes. Dr. Ben Lynch talks about this. They do not completely agree with eachother on everything. But I appreciate the works of both. There are probiotics and certain cofactors to a certain gene to break down histamine, otherwise the bucket will overflow. Also a lot of food contains histamine like everything that is fermented and strawberries. I take quercetine myself or green tea which contains it as well. Vitamin C and I think it was zinc are also needed.
@dana102083
@dana102083 3 года назад
Never take folic acid in any case. Synthetic nutrients are 💩.
@saintjabroni
@saintjabroni 2 года назад
@@dana102083 👌🏼 They should be taken off the shelves immediately. I don’t know why they’re not… The synthetic folic acid is also put into food stuffs such as Cheerios. What the hell is going on… Oh, I remember - FDA promotes the public to be poisoned.
@dana102083
@dana102083 2 года назад
@@saintjabroni agreed very much. The diets they promote are financial deals with big agriculture and big pharma. A money transaction to line pockets and keeps everyone sucking at the teet.
@33johnson19
@33johnson19 5 лет назад
So what's the solution?
@LuvBugBlaqkHart
@LuvBugBlaqkHart 3 года назад
Nutrient therapy
@royedwards51
@royedwards51 3 года назад
Mehtylfolate
@areyouusingthatsquatrack8256
@areyouusingthatsquatrack8256 3 года назад
@@royedwards51 he just said some kind of methylfolate makes it worse.
@areyouusingthatsquatrack8256
@areyouusingthatsquatrack8256 3 года назад
@@LuvBugBlaqkHart should we not eat or drink foods high in folate too, is it as bad as taking folic acid supplements? like spinach and lentils and orange juice i mean not fortified foods.
@olekike
@olekike 5 лет назад
so what supplements do you give someone that is undermethylated but has depressive/schizophrenic issues?
@godscovenant857
@godscovenant857 4 года назад
I was given an antihistamine called MITIL. It worked for me 🤗
@mjdawd4846
@mjdawd4846 3 года назад
God’s Covenant antihistamines are like antibiotics.. have negative long term side effects. Go with choline, tmg, creatine, glycine amd maybe sam-e
@mjdawd4846
@mjdawd4846 3 года назад
Creatine and glycine for sure, try adding tmg and choline an well.
@LuvBugBlaqkHart
@LuvBugBlaqkHart 3 года назад
@@mjdawd4846 hey you're not a doctor so please don't be giving out unsolicited advice
@user-dd7fw8ox3c
@user-dd7fw8ox3c 3 года назад
Try Glutathione, NAC and MSM
@djammer
@djammer Год назад
This doesn’t make sense to me… how do you increase methylation without b9
@freedomwarrior5087
@freedomwarrior5087 11 месяцев назад
Maybe with TMG?
@revanchdg
@revanchdg 10 месяцев назад
L-Methionine
@erilsard1873
@erilsard1873 Год назад
I have experienced very severe neurological disorders with the use of PPIs. I have the characteristics under methylation _ I learned this with my own research after the disorder_ I can't get rid of paresthesias, especially pins and needles. What can you suggest me about this?
@Ceej474
@Ceej474 Год назад
B12 injection asap. Looks at the Facebook groups vitamin B12 wake up. Get your b12, iron and folate checked asap, but bear in mind the reference ranges are ridiculous and you literally have to be close to death before you will show as B12 deficient. PPIs significantly reduce absorption of B12. Tablets will not work for this level of damage, don't waste time on supplements. Get bloods tested then immediately get your first injection privately hydroxocobalamin and wait for several weeks and see how you feel. You may need them monthly or 6 weekly to heal. Also bear in mind you can have too much of a good thing and spacing them out works better for some, whilst others need more. Good luck.
@jeffreyconnor9769
@jeffreyconnor9769 10 месяцев назад
Folic acid is NOT in fact folate. Folate is a GROUP of not shelf stable B vitamins. Synthetic Folate aka Folic Acid does not contain all of the vitamins. Folic acid is a suspected carcinogen. It is processed in the liver because it’s toxic and it can build up there and cause a lot of problems with nutrient absorption and toxicity. folic acid from processed 0:03 0:03 food and supplements can cause anemia. It can also mask other vitamin deficiencies on the test panel.
@bustingatdaseems
@bustingatdaseems 3 года назад
So what do undermethylators take then?
@saintjabroni
@saintjabroni 2 года назад
No response here in months… Wow.
@bc9086
@bc9086 2 года назад
I’m still waiting as well 🥹
@Philly1958
@Philly1958 5 лет назад
Does this hold true even if you have the MTHFR defect?
@i.ehrenfest349
@i.ehrenfest349 4 года назад
@Google Barbara Lerner Spectre Eh.....MTHFR is a real thing. It's a gene SNP.
@celestialdreams3022
@celestialdreams3022 4 года назад
I have been wondering this too!!!!
@LuvBugBlaqkHart
@LuvBugBlaqkHart 3 года назад
Yes. I have MTHFR heterozygous mutation and I cannot take folate due to being undermethylated. I actually overdosed myself for years not realizing it until just this year. If you want to know for sure have your folic acid (folate) serum tested. My doctor who was trained by the Walsh Institute (this dude's institute) said that the normal range is >2.8 ng/ml. You can compare that to your results if you decide to get it tested. Hopefully that helps.
@areyouusingthatsquatrack8256
@areyouusingthatsquatrack8256 3 года назад
@@LuvBugBlaqkHart should we not eat or drink foods high in folate too, is it as bad as taking folic acid supplements? like spinach and lentils and orange juice i mean not fortified foods.
@LuvBugBlaqkHart
@LuvBugBlaqkHart 3 года назад
What if you're undermethylated and have adverse reactions to SSRI's, melatonin supplements, 5-HTP supplements, and anything that increases serotonin? I can't handle serotonin at all but I was recently diagnosed with pyrrole disorder and undermethylation. I'm going to start taking SAMe but I'm worried I'm going to have a negative reaction to that as well. I've just had so many bad experiences with doctors that I want to get a second opinion but I have no one else to ask who knows about this stuff.
@user-dd7fw8ox3c
@user-dd7fw8ox3c 3 года назад
Glutathione, NAC and MSM will help
@jpfitness2242
@jpfitness2242 3 года назад
After your pyrrole disorder gets under control you may have more tolerance to things. Before my pyrrole therapy I had bad reactions to everything. I'm also undermethylated and SAMe helps a lot.
@dana102083
@dana102083 3 года назад
Consider a ketogenic diet. Please search dr georgia ede who is a psychiatrist that uses it in her Practice 🙏 removal of sugar hs numerous positive changes in how our cells function, especially the mitochondria.
@zambrocca
@zambrocca 3 года назад
@@jpfitness2242 hi, could you be more specific about pyrrole therapy? i'm just taking SAM-e for histamine intolerance and seems to help in some way. (i just started to take it) thank you.
@jpfitness2242
@jpfitness2242 3 года назад
@@zambrocca I've heard that if someone doesn't need at least 300mg of b6 per day they probably don't have pyrrole disorder. I agree to that. 300mg per day is a good dose. I take 400. Zinc varries. Some people may get by with 75 or 80mg per day. I think 100mg per day in 2 50mg doses with food is best. I personally take 150 per day because I have poor absorption. When you take high zinc you have to make sure your copper levels don't get low. If you develop muscle weakness your copper may be low from high doses of zinc.
@jordanj.5681
@jordanj.5681 4 года назад
Folate makes me anxious and fuelled with adrenaline and spaced out. Am I overmethylator? I found I could use niacin to combat it and return to baseline.
@enisturkkan5627
@enisturkkan5627 4 года назад
I am the same. Have you figured it out?
@jordanj.5681
@jordanj.5681 4 года назад
Enis Türkkan nope.. I’m jus gonna remove all supps and slowly add back in and watch for changes
@captainfalcon7227
@captainfalcon7227 4 года назад
Sounds as if you’re under methylated mate your going the wrong way
@GoToHow
@GoToHow 4 года назад
@@captainfalcon7227 You are right. I think you are under one with neurotransmitter imbalance same as me.
@i.ehrenfest349
@i.ehrenfest349 4 года назад
He was talking here about UNDERmethylators being intolerant to folates.
@Histamindetox
@Histamindetox Год назад
It’s a copper issue
@joriwilkinson
@joriwilkinson 4 месяца назад
Too much or too little?
@Borka642
@Borka642 Год назад
What if those people are pregnant or trying and need to take folic acid?
@kto-totam2876
@kto-totam2876 3 месяца назад
So why are they intolerant to folates?
@grannys3426
@grannys3426 3 месяца назад
Good question. I got the impression - but it's not fully explained - that the individual's genetic expression determines whether undermethylated people can tolerate folate. Per this video, some undermethylated people "get dramatically worse" from folates--not all undermethylated people however. As I heard this, folates generally lower serotonin activity. They impact neurotransmission, esp. serotonin, dopamine and norepinefrine. Perhaps undermethylated patients whose imbalances and deficiencies are already causing depression, experience more extreme reductions due to their genetics.
@royedwards51
@royedwards51 3 года назад
That's why you take methyl folate. You have to take the correct form.
@dana102083
@dana102083 3 года назад
Some people do not tolerate that either. That's the issue. I think as some people have spme overmethylation amd some snps undermethylate so nothing is ever happy.
@lorrainedavis6006
@lorrainedavis6006 6 лет назад
Good to know but you don't present how to work with it. So....
@SufyMusic
@SufyMusic 6 лет назад
he does in his book tmg methionine SAMe
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