I discovered your channel about a month before taking the MCAT, and I am so so glad I did! Your videos are so helpful, I don't think I would have done nearly as well as I did without them. I can only imagine how much time you must've spent making these videos, so from the bottom of my heart thank you for all your hard work! I hope medical school is treating you well.
Hello sorry to ask you but I will be taking the mcat in two months and I super worried do you recommend any study strategy or any advise for me please let me know.
I really like the fact that u show us the bigger picture and give us a visual map to see how pathways are connected to each other without making it too complex
Very high energy which I found a bit annoying at first, but by the end of the video I understood my entire anki deck on lipids that has been confusing me for DAYS. Well done, sir. Well done. Lipids have now have a legit connection to the other concepts in my biochemistry/metabolism semantic network Keep doing you my man. And thank you!
This is so incredibly valuable and insightful. It adds much needed depth to some of the review books. Understanding how the various lipids are formed via the mechanisms makes it easier to remember content about lipids!
So what I meant is that the -OH on the original compound is lost…. But that OH gets an added H+ and leaves as a water molecule… so to clarify the -OH on the original molecule is lost as a water molecule
Can someone help! At 1:35, he adds electrons to the OH group so that it can leave. However, I though OH- was a bad leaving group so how does that work??
There are biological enzymes that stabilize the OH, therefore facilitating the OH to leave as a leaving group… a common example is an enzyme protonates OH so it can leave as H2O
14:20 time stamp. The carbohydrate has a positive formal on the oxygen and I'm guessing delta positive on the carbon. Shouldn't O- as an nucleophile attack the formal positive charge O, instead of the carbon. I'm assuming there is no serious steric hinderance. Can anyone explain why it attacks C and not O?
Also, keep in mind that generally speaking, biological enzymes catalyze all these reactions, which allow formation of several highly unstable intermediates.