Learn why PRP should not be made in Vacutainers. Vacutainers contain endotoxins and are not FDA cleared to make PRP. You can learn more about how to make PRP in a way that is safe, legal, and effective on our website: www.prplabs.com
@@KrisD007 ACD-A is a commonly used anticoagulant and is generally considered safe. However, the issue with vacutainers is not this ingredient. The issue is that vacutainers are not FDA cleared to create PRP and that they may contain endotoxins - according to the manufacturer of Vacutainers, BD: "BD does not claim that any of the Vacutainer blood collection tubes are endotoxin free." www.bd.com/en-ca/offerings/capabilities/specimen-collection/blood-specimen-collection/venous-collection/bd-vacutainer-blood-collection-tubes/vacutainer-blood-collection-tube-faq/general-tubes-faq#:~:text=(10%20boxes).-,Q.,collection%20tubes%20are%20endotoxin%20free.
Hello i have been asking loads but no answer good evening sir hope you are doing well. What sort of Blood Collection Tubes Can i put blood in and drink it from don't need a lot but i need to try this so i want to do it in a save way but no one will let me know im getting left to do this in a unsafe way please help many thanks take care
Very informative! Just a question: FDA approval is required only in the United States, correct? But I don't live in the US and I'm interested to see a dermatologist for PRP therapy for hair regrowth. I'm just watching a bunch of related videos to know more about the procedure before take that decision. But I'm a little afraid right now. How can I make sure that they will not inject those endotoxins on my scalp?
The FDA is a US-based regulatory agency and it's jurisdiction would not extend to countries outside of US jurisdiction. We can't advise on how to find appropriate medical devices outside of the US.
The way to make sure that endotoxins are not injected into your scalp is to call your dermatologist and ask what brands and models of PRP tubes they use. With some patience and encouragement they should provide you with that information. Once you have the brands and models that they use, research that info to find out if the tubes contain endotoxins or not. If they don't, make your appointment for the procedure. At the appointment, right before they are about to start the procedure, verify for yourself that they are indeed using the PRP tubes they said that they use that are endotoxin free.
sir plz tell centrifuge @ rate ,or how much time we have to centrifuge at what rpm single or double spin ? and how much sample of prp in ml is needed for 1 sitting ?
The glass BD ACD-A Vacutainers (the ones he's holding) have been proven to not contain endotoxins. They have been repeatedly tested and verified in several published studies to be not only endotoxin free, but are ideal for even intra-articular PRP injections in which absolute sterility has to be maintained.
This 2004 study found endotoxins in glass BD Vacutainers: academic.oup.com/clinchem/article/50/11/2215/5640121 It's also worth noting that your confidence of BD ACD-A Vacutainers being endotoxin free is not shared by the manufacturer of these tubes. To quote BD's own website: "BD does not claim that any of the Vacutainer blood collection tubes are endotoxin free." www.bd.com/en-ca/offerings/capabilities/specimen-collection/blood-specimen-collection/venous-collection/bd-vacutainer-blood-collection-tubes/vacutainer-blood-collection-tube-faq/general-tubes-faq#:~:text=(10%20boxes).-,Q.,collection%20tubes%20are%20endotoxin%20free.
I'm not sure where there's any confusion - you can read the study we posted above your comment. A published, peer-reviewed study has demonstrated the BD Vacutainers were found to contain endotoxins. It's not a hypothetical matter - it's a documented fact.@@bballev2
'The 5-mL heparin Vacutainer Tubes (lot no. 3224585) were positive for endotoxin (10 ng/L), whereas another lot of 5-mL tubes (lot no. 4029101), 4-mL plastic heparin tubes, and 10-mL glass heparin tubes were negative for endotoxin (
The 5th question on the BD.com FAQ states that all their blood collection tubes may contain endotoxins: www.bd.com/en-ca/offerings/capabilities/specimen-collection/blood-specimen-collection/venous-collection/bd-vacutainer-blood-collection-tubes/vacutainer-blood-collection-tube-faq/general-tubes-faq This is not a benefit, but rather a disadvantage that comes with less expensive manufacturing processes.
Is it illegal to inject PRP made with vacutainer (or any other vessel which is not FDA cleared as PRP kit) to patient in the US? Or is it just literally ‘not good for health’?
It is against FDA regulations (and therefore illegal) to inject PRP into a patient that was prepared in a device that has not been FDA cleared for PRP preparation. Additionally, it is not good for health to inject endotoxins (which are found in vacutainers) into a patient's body.
Nah, of course they have to sell. I work with surgeons and we use BD tubes for PPP eye serums. Are you saying we are putting endotoxins in our patients’ eyes? Lol. We use prp tubes from a different company for other eye and skin treatments too. So far, no complains of endotoxins from our patients cos our team of doctors could have known that, right?
Please share the name of the hospital you work for so we can help inform your patients that YES - you are likely putting endotoxins into your patients' eyes. BD says on their own website that all of their blood collection tubes contain endotoxins. Read for yourself on the 5th question on this FAQ: www.bd.com/en-ca/offerings/capabilities/specimen-collection/blood-specimen-collection/venous-collection/bd-vacutainer-blood-collection-tubes/vacutainer-blood-collection-tube-faq/general-tubes-faq "Q. Are BD Vacutainer blood collection tubes endotoxin free? A. No, BD does not claim that any of the Vacutainer blood collection tubes are endotoxin free." Sadly a lot of doctors do not understand the risks of illegally using blood collection tubes to make PRP. That's why we release educational content like this video. If the doctors at your clinic want to make PRP that is safe and effective for your patients, then they should use a medical device that is FDA cleared for the preparation of autologous PRP.
Seriously, surgeons have had enough education. They are very specific and careful when it comes to what they put in their patients’ eyes. I make the eye serums myself and I speak with clients. So far, the only negative comment I got was its cost. Very effective but pricey. I understand you want to sell but I am also trying to tell people that this is what we do so they can have options. For additional info, we do prp for severe dry eyes too and we use prp tubes for more growth factors. I don’t really share confidential infos.
@@PRPLabs BD is FDA approved too. BD do not claim that they are endotoxins free. It’s like saying they are not peanut free facility for precaution. The only difference of the bd tubes to PRP tubes is the number of growth factors.
@@SeaBee1223 BD Vacutainers are class 1 medical devices which are FDA cleared for general chemistry purposes only. These are very different from class 2 medical devices that are specifically FDA cleared for preparing autologous PRP. Saying BD is "FDA approved" is not only inaccurate terminology (since they are FDA "cleared" not "approved") - it's also irrelevant because their FDA clearance has nothing to do with the preparation of PRP. The manufacturer's of FDA Cleared PRP devices will all proudly acknowledge that their products are endotoxin free. While some people are allergic to peanuts and may avoid food manufactured around peanuts, ALL patients want to avoid endotoxins being put in their eyes. So it's probably best that you and your team do everything you can to avoid that, even if that means using appropriate medical devices for your procedures.
@@SeaBee1223 If your surgeons don't know that BD tubes are not endotoxin free, then they have not had enough education. Are they using PRP tubes that are endotoxin free? Or, are they using PRP tubes that contain endotoxins and they are injecting endotoxins into patients? As for patients only complaining about the cost: Do you really think patients would know when endotoxins are being injected into their body and their body is reacting at a microscopic level? You've said you're using BD tubes. BD states that they are not endotoxin free. Therefore your surgeons are injecting endotoxins into patients because they are using BD tubes.
