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Martin Picard: Mitochondrial Psychobiology, Neuroplasticity, Stress, and Brain Health 

BRAIN PONDERINGS podcast with Mark Mattson
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Mitochondria are best known as the powerplants within cells. But recent research is revealing that mitochondria play fundamental roles in regulating the structure and function of neuronal networks and the behaviors that those networks control. Martin Picard directs the Mitochondrial Psychobiology Group at Columbia University. In this episode I talk with Dr. Picard about: the biogenesis and movement of mitochondria within cells, the disposal of damaged mitochondria, the diversity of mitochondria within and amongst neurons in the brain, how this diversity contributes to neuroplasticity, and how aberrancies in mitochondria are involved in mental and neurodegenerative disorders. We also talk about how ‘bad’ and ‘good’ stress affect mitochondria.
LINKS:
Reviews on Mitochondrial Diversity and Psychobiology:
file:///Users/markmattson/Downloads/s42255-023-00783-1%20(1).pdf
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
Mitochondrial Diversity and Anxiety:
www.ncbi.nlm.nih.gov/pmc/arti...
Human Brain Map of Mitochondrial Diversity:
www.ncbi.nlm.nih.gov/pmc/arti...

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5 авг 2024

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Комментарии : 8   
@rishiskumar.360
@rishiskumar.360 3 месяца назад
Great conversation between two of my favorite neuroscientists, Dr. Mattson and Dr. Picard. Lots of learning moments including that we are warm-blooded due to mitochondria, free intact mitochondria are in the saliva and blood, and glia are most affected by psychosocial experiences. Profound that mitochondria might have been the reason lungs and cardiovascular systems evolved to bring oxygen to them. Thank you both! 🧠
@tracy-shizhang2598
@tracy-shizhang2598 8 дней назад
Super interesting and intriguing topic! Thank you!
@mathew9851
@mathew9851 3 месяца назад
Looking forward to listening to this conversation!
@anandpbgupta
@anandpbgupta 3 месяца назад
Just finished listening. Fascinating conversation. It will be good to know specifics of how to maintain and improve brain mitochondrial health.
@eugeniebreida1583
@eugeniebreida1583 3 месяца назад
Yet another fascinating view into cutting edge research, and another humble bright-light sharing with us. Godspeed!
@LeahBensonTherapyTampa
@LeahBensonTherapyTampa 3 месяца назад
Martin Picard is the man! Love how he explains mitochondria.
@iowkeatsendymion
@iowkeatsendymion 3 месяца назад
Very interesting! I am a long-distance runner interested in learning and practising how exercise and intermittent fasting greatly benefit health. Thank you Mark for inviting so many great scientists to this podcast. Very inspiring !! From my simple association, the MHI is a bit like the VO2Max, an index that shows people's fitness levels.
@studentaccount4354
@studentaccount4354 3 месяца назад
🎉Yay! Amazing topic. 😊TYVM
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