Myasthenia gravis - causes, symptoms, treatment, pathology 

I got it when I was 13. I’m 25 now. I take prednisone, pyridostigmine and I’ve had the thymus gland removal. For me my symptoms has become less and less frequent but it’s not completely gone

I am 63 years old and I have been suffering from the weakness periodically from the age of about 16. Every Time I went to a doctor all they wanted to test me for was MS. I was finally diagnosed 6 years ago. When I walked into the Neurologists office my first words to her were, "You are not testing me for MS I do not have MS I have been tested for it for the past 40 years and I don't have it" she told me " No you don't have MS but I do think I know what you do have." She did a neurological evaluation and then did some blood work and told me to come back in a 2 weeks. I was pretty sick at the time, but agreed. I went back and I was actually grey at the time. I was so weak I could barely walk even with the aid of my walker. She told me what I had was Myasthenia Gravis. She explained it to me in language I could understand, and told me I needed to be admitted right away. Well this was 2 days before Christmas and I had 35 people coming for Christmas dinner. I asked if it could wait till after the first of the year. She took one look at me and said you will not be alive at the first of the year, if you don't get treatment. I told her the situation I was in and we agreed I would go in right after Christmas. I was with my daughter in law and we had to stop and get a last minute gift for my grandson, I stayed at the front of the store because I felt so horrible. And to make it even worse people kept stopping and asking if I was okay and did I need an ambulance. Anyway she got the gift and I felt so bad I almost told her to take me back to the doctor so I could go to the hospital. By the time I got home all I could do was fall into a chair. I was beat, and in walks a friend ( one of my daughter in law's uncle's, who just happens to be a chief.) Any way he told me that was now his kitchen and if I wanted anything I was to tell one of my grandchildren and he would get it. Anyway Christmas went off great and I went into the hospital a couple of days later. Then came my first experience with plasmapheresis. I want to tell you, doctors need to know there is more out there then MS. I was beginning to think I was crazy, I even asked my primary care doctor to send me to a psychiatrist, because I had become convinced of it. After a couple of sessions, he revealed that I was not crazy and they symptoms were not in my head.

i got diagnosed by this. i have thymoma (not yet removed till now) , you guys probably won't believe me , but i actually a personal trainer . i've been on physical activities / organisation since age 16 . i got diagnosed at age 24 . i am a guy, not even young woman / old men yet. my body fat around 11-13 % ( 72 kg, 172 cm, the body fat depend on what i do [cut/bulk] ) . my bench press around 135 kg , i can do front and backflip , i can do tornado kick both front and back foot. don't give up people, even i diagnosed with this muscle grave sickness, i still can be superior on this physical activities. don't let this sickness take over your life.

I really love your videos! You make it easier to grasp the whole concept of whatever topic you discuss in a few minutes!

Symptoms started at age 15 and I’m 19 now it’s been challenging but I still hope for the best.

I have congenital myasthenia which is kind of like this but I was born with it. From some research I’ve found that it’s very similar to this so this really helped me understand what I have just a bit more thanks :)

Thank you for all the videos you have posted! Its been a huge help! :)

I'll be having my thymectomy this Friday. I was diagnosed last January when I was in crisis state and being in the ICU for 2.5 weeks. After reading these comments, I'm happy to see I'm not alone.

Excellent video! I'll remember this for my neuropath exam:D

Osmosis you deserve all the money I give to my university! Thank you again!

I love your videos! I am an Optometry student and these videos have been so helpful to me! Thank You So Much!

Great video on the topic although I think it may have been important to note that when treating myasthenia gravis it is important to watch for symptoms of cholinergic poisoning as this can be fatal. When testing for myasthenia gravis one must always carry it out in facilities capable of having respiratory support since one of the symptoms of cholinergic poisoning is paralysis (can impact the lungs and cause resp. paralysis)

Ur voice is music to my ears ! :D Thanks for all the amazing videos

I am so impressed by the quality of this short video review on a topic that can be challenging to learners. Kudos to you! I am studying for my Pulmonary boards, and this was a neat review of basic science concepts. For other learners out there, don't forget that Myasthenia gravis crises should be treated aggressively with plasmapheresis or IVIG or high dose steroids. Make sure to monitor their respiratory status closely, and consider elective intubation if vital capacity (VC)

Thanks! This is the easiest way to understand the disease.

Tks for this video l has received one case of myastenia crise today...

Such a great concise informative video. Thank you very much osmosis!

Thank you for the information! Very well presented.

I ABSOLUTELY thought that drawing of the junctional folds in the synaptic cleft were microvilli/cilia and spent about an extra 40mins trying to figure that out, but otherwise great resource! Thank you for creating it!

Thank you! i have recently been diagnosed with MG, this video was helpful to share with family and friends

I went to a new job today. Everyone else there was fine, before lunch I became so weak and painful that vomited from the pain. Ive never experienced anything like this. I recently went through 6 full weeks of Shingles and am getting a little concerned (okay alot concerned). I have other auto-immune disease as well, i.e. crohns, hashimotos to name a few.

Hi I really love your videos. It is very informative and easy to understand.

you made pathology fun thanks

Great video!! very helpful and fun graphics !! good review at the end

The video was very useful for exam. Thank you.

Best explanation of myasthenia gravis so far

It was really helpful.. Thank you

Excellent video i remember this for my neuro exam you make it easier!!Thank you

Great video! There is also Seronegative MG (can be confirmed via SFEMG, Tensilon test) and 3 other antibodies that have been recently discovered- these include LRP-4, Agrin, and Cortactin.

You made study fun and easy ...thank you so much for your awesome video's...

Thank you so much Osmosis😍😍😍

very good video , thank you

These videos are amazing! Keep up the good work!

Really helpful! Thank you for the animation.

Great Video thanks...

Thats just amazing how concise your videos are ! please make a video on all pathways of complement system !

Thank you!

I first got diagnosed with this when I was 28 years old. It was the hardest thing in my life. Nobody knew what it was OK going to different specialist. I am 41 years old now take your meds three times a day and you’ll be fine. Sorry for the people they got diagnosed with thisis very hard but this is the way that we are now

Your and Dr uut lectures videos are osm

thank you!

Amazing !! this video helped me a lot with my neurology exam!! love you guys ♡♡

Excellent video

Well done thank u very much🌹

Hello I love your videos, you make learning fun but can I suggest a correction? Myasthenia is a Greek word not Latin from Greek "μυς" meaning muscle and "ασθένεια" meaning weakness. Thanks

Thank you

you rock!!! please keep the videos comming

thanks

nice presentation

Best videos...!!! Very helpful

Great explanation! :)

I got myasthenia when I was 7 yrs old, and I have had my thymus removed at age 8 or 9 and don't take prednisone anymore, but I still take pyridostigmine. I am better, but it's not gone yet and I have had around 3-5 myasthenic crisis, (which were very severe).

Thanks a lot sir 🤗

thanks osmosis...

From an ex-mentor teacher presently working in cancer education, I am appreciative of this excellent presentation. So well done, the visual along with the spoken is effective. Thanks.

Thank you so much ❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️

thank u sir..

amazing thank u so so much

Keep up the good work 👍

شكرا جزيلا

Pharmacy student here: your videos help tremendously and follow our pathophys notes almost exactly

thank u nice video

plz make vedio about GBS

thanks for swift explanation

Your videos helped me a lot

Nice one

perfect! It helps me with my pharmacology exam

Stunning!

Thank youuu✨✨

Great job! Thank you!!!!

is there a certain anti-body test that can identify if you have this disorder? some of the symptoms mimic many other A/i diseases, or other diseases in general. thank you

thank u

This topic was covered in class last tuesday but i fall asleep in class Now i know ,,tq tq soo much

The thing I love most about Osmosis is the Arabic translation❤️❤️❤️🇩🇿

Thanks alot .... 🤍

That’s a perfect video , I am preparing for NCLEX and that’s help me a lot 🔥

Thankyou!!!!!!

Great video, all really useful for my exam revision (Y)

شكراً🌼🌿

Does beta blocker causing myasthenia gravis symptom from blocking the muscle receptors?

Is there any fill treatment for the diseases

plz do thymomas......

Great Job!! thanks

More treatment options: intravenous immunglobulin (fast effect start), cortisole, some other immunesuppresants.

My favorite channel ever❤️❤️

Thanks 👏💜

Was Dx with this disorder just over 2 years ago although by history have had it just over 25 years. I am male, 69 yrs of age and when I first started having "problems" in the military I was told that I was not conditioning properly. I worked hard to stay in the military until I was able to retire but continued to have episodes of sudden weakness and double vision. Recently I was admitted to hospital because I kept falling, could not get up. I was found to have URI, UTI with aggression of Myasthenia Gravis. Again, more PT, OT and god knows how many new medications. I also have COPD and asthma. Looking to try to get into an assisted living facility.

Lol, this was on my final this morning. Barely missed it!

Hi.. Im a little bit confused now.. Is it muscuranic or nicotinic receptor?

Nice

Estos videos me sirven tanto *w * muchas gracias!

My father has myasthenia gravis. He is 78. His condition has gotten progressively worse over a span of 12 years. I want to help my father get better but l don’t know how. I flew in my parents for Christmas from Florida to my home in Utah thinking we would have a beautiful holiday and it turned out that the cold weather greatly affected him. My father got weaker than usual and l was devastated.

thank you so much sir.. You are saving lives.

Thanks to you we are greatful

Thank you alot

Great video. Relation to Graves' disease please

Nice....

thankyou for this short video

Just curious that will the removal of thymus cause in any problem in normal immune system of person ?

Best video

Thank you Sir ❤️