Hi,
this question was asked in NEET-MDS-2022.
Q. Which of the following precancerous lesions has malignant potential?
a) OSMF
b) Erythroplakia
c) Oral lichen planus
d) Syphilitic glossitis
Oral submucous fibrosis (OSMF) is an oral precancerous condition characterized by inflammation and progressive fibrosis of the submucosal tissues resulting in marked rigidity and trismus.
Erythroplakia means "red patch" and refers to a lesion with a reddish appearance that doesn't have another obvious cause. They appear in the mouth or throat. They tend to be flat and have a velvety texture. They may have white spots on them. Some have a tendency to bleed easily.
Malignant transformation rates of erythroplakia are very high ranging from 14% to 50%. Because of this high rate, early detection and immediate surgical excision are recommended. Histopathological features of erythroplakia show at least some degree of dysplasia and even carcinoma in situ or invasive carcinoma.
Oral lichen planus is a chronic inflammatory condition that affects oral mucous membranes. It may appear as white, lacy patches; red, swollen tissues; or open sores. These lesions may cause burning, pain or other discomfort.
Syphilitic glossitis
In tertiary syphilis, the tongue may be involved diffusely, and appear large, lobulated, and irregularly shaped.
This lobulated pattern is termed interstitial glossitis and is thought to be the result of contracture of the lingual musculature after healing of gummas.
Diffuse atrophy and loss of the dorsal tongue papillae produce a condition called luetic glossitis.
In the past, this form of atrophic glossitis was thought to be precancerous, but several recent publications dispute this concept.
15 окт 2024
