NEOPLASIA Part 11: GRADING and STAGING of cancer Click on website ilovepathology.... for more content for undergraduate students in pathology. Please feel free to post queries or comment on the video😊 Good luck.
my college professor covered whole neoplasia so quickly, that i was unable to understand. and my coaching videos also didnt explained this nicely. you save me, thank you so much sir. i have exams from next week and thanks to your videos, i am confident. please keep making more videos. >.
thank you for this concise depiction regarding grading and staging. If i may sir, i have inquiry about an also unusual grading i come across every now and then which is de-differentiated tumor, i believe it's exclusively concerning liposarcomas, do you have any thoughts about its meaning? And finally i hope you continue with this series which i delightfully watched from the beginning :)
Yes..as you mentioned it occurs in liposarcoma.. Basically it is transition of well differentiated liposarcoma to another type of sarcoma(not Lipomatous) The other sarcoma can be any high grade sarcoma,like pleomorphic sarcoma,osteosarcoma,rhabdomyo sarcoma eyc.. The mechanism behind is very complex though!! And genetic!..involves amplification of certain genes.. Note that it is not specific for liposarcoma..it can occur in carcinoma too. Eg..endometrial carcinoma can show dedifferentiated areas.. Hope this helps 😊
