New Immune System Treatments for Fibromyalgia Pain: Dr. Ginevra's Research Update #2

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New ways to treat fibromyalgia are just around the corner! Recent research implicating the immune system in fibromyalgia pain should open many potential new treatment options. This video reviews published case reports on the immune-modulating drugs Tocilizumab and methotrexate in reducing fibromyalgia pain and discusses the potential roles of Rituximab and Bee Venom therapy. You can find study references below.
Learn all about the immune system and fibromyalgia pain here • New Research Reveals R...
About me: I graduated from Tufts University School of Medicine and am board-certified in internal medicine. After developing fibromyalgia in medical school I was able to find integrative treatments that helped me feel much better. I share my complete treatment approach in my book The FibroManual amzn.to/3Uql7wg
In my videos I hope to inspire everyone dealing with #fibromyalgia to remember they are #fibrofierce!
Sign for my email newsletter for all things #drginevra and #fibro at www.drginevra....
References:
Goebel A, et al. Passive transfer of fibromyalgia symptoms from patients to mice. J Clin Invest. 2021 Jul 1;131(13):e144201
Tang KT et al. Subcutaneous Tocilizumab May Be Effective in Refractory Fibromyalgia Patients. Biomedicines. 2023 Jun 21;11(7):1774
Omoigui S, et al. Relief and Resolution of Fibromyalgia Symptoms with Low Dose Methotrexate - The Origin of Pain is Inflammation and the Inflammatory Response Rheumatology 2014 4: (1)129
Sung SH & Lee G. Bee Venom Acupuncture Effects on Pain and Its Mechanisms: An Updated Review. Toxins (Basel). 2021 Aug 29;13(9):608
Li D et al. Preventive Effects of Bee Venom Derived Phospholipase A₂ on Oxaliplatin-Induced Neuropathic Pain in Mice. Toxins (Basel). 2016 Jan 19;8(1):27

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20 окт 2024

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Комментарии : 69

@kaylabryson1932 9 месяцев назад

Great update . Looking forward to anything you post

@thefibroshow 9 месяцев назад

More to come!

@johnboyt611 9 месяцев назад

I listened to you videos with fascination. I have been diagnosed with fibromyalgia without my doctors really investigating properly. I asked for the blood tests you specifically say... my doctor told me there is no such thing as these tests and point blank refused me! She was VERY ignorant about what fibromyalgia is for a start. I tried to educate her. As usual, just ended in an argument. I'm following the carnivore diet and I'm starting to feel a lot better: lost a lot of weight which is annoying as I'm a gym goer but I don't feel so awful. Keep up the great work. ❤

@thefibroshow 9 месяцев назад

Glad you have found some benefit! Sadly your experience with doctor is far too common.

@karenjeffery1998 Год назад

Thank you so much for the updates and interruptions of the current research.

@BRS5 Год назад

Thank you for your work! You look and sound very fibro strong today!

@thefibroshow Год назад

Awwwh, thank you! I am getting fiercer every day as I recover from recent life setbacks.

@BRS5 Год назад

@@thefibroshow I follow you and totally understand. You support us, we support you!

@pastelprintshop Год назад

Thank you Thank you Thank you for your work and sharing about this ❤❤❤❤

@thefibroshow Год назад

You are so welcome

@TheSpeedyone2 Год назад

I'm excited!!!!

@tomwoods1725 Год назад

Thank you for you do for us!

@thefibroshow Год назад

My pleasure!

@chaitra.nreddy4044 8 месяцев назад

I took maharasanadi kadha ,and ayurvedic tonic,which healed pain completely. For fatigue,neuroplasticity helped. Pl try this Am from India.

@lorianthony4892 Год назад

Thanks so much for your online help for us!! I have studied your book for about 6 years. It is very helpful

@thefibroshow Год назад

You're very welcome!

@TheSpeedyone2 Год назад

When this first happened to me....long story......... I said 24 years ago, this pain is exactly like the HV and genital wart pain I had, where my legs would shake and scream in pain, like severe RLS....and so much more to the story........but, this is big, and about time!

@Truerealism747 Год назад

HV virus apparantly can cause fybromyalgia

@METTE-MAR 9 месяцев назад

Diagnosed with FMS in 2010. Suffered from long COVID for 2 years. Low histamine diet and ketotifen have been a life safer for me as it gave me the strength to keep fighting the medical gaslighting. Turns out I have hypogammaglobulinemia + specific polysaccharide antibody deficiency AKA Common variable immuno deficiency (CVID). I get 3 weekly IVIG and no longer bedridden. But the older I get the more issues from hyper mobility. So the immune system is definitely involved as is histamine intolerance ( ➡️ anxiety!!). Maybe some variants on the MTHFR genome.

@pfranks75 Год назад

I’ve dealt with the diagnosis of fibromyalgia for about 20 years. I’ve experienced anxiety all of my life. I’ve been more the exception of the rule in many ways.

@kiblet 9 месяцев назад

They say that LDN works as an immunomodulator in the other diseases they're using it for, the more "classically autoimmune" diseases. Has there been any theorizing that LDN is also working for FMS patients who are helped by it, by acting as an immunomodulator in FMS? I find it odd that LDN researchers shrug and say they don't know how it helps FMS, but I am grateful that they at least offer it to us.

@catofthecastle1681 Год назад

I was diagnosed with fibromyalgia in 2006. Six months before, I was cleaning in the yard and pushed my hand into a nest of red wasps(Polistes carolina). I had over 17 stings and have always thought their neurotoxins and chemicals caused my fibromyalgia! My doctor initially threw it out as a cause, but I still think this was a cause. Could I be right?

@dubaloo Год назад

My immune system seems to work overtime. Except for having the Asian flu when I was an infant and a cold 8 years ago, I haven't been sick at all. With fibromyalgia I feel like I have the flu all of the time. I've taken everything from A to Z for the pain and nothing has helped, until a friend introduced me to kratom, and it's been a godsend for the pain.

@kaylabryson1932 9 месяцев назад

What is Kratom

@dubaloo 9 месяцев назад

@kaylabryson1932 If you Google it, (kratom powder) you can find out more than I could put in a text. Not everyone will be able to take it. I'm so thankful that I am able to.

@VickiFrederick-s8c 5 месяцев назад

Told I had undifff connective tissue disorder along with fibromyalgia. Thanks for the wi rk you do

@moduqueRN Год назад

Do believe there is an autoimmune component with fibromyalgia. Symptoms significantly worsened once I discontinued prednisone for my lupus.

@robertscott4007 Год назад

Great video

@kimm5555 3 месяца назад

I am so tired of trying this and that and getting minimal results. Some days I wonder how much more of this I can do.

@thefibroshow 3 месяца назад

The grind can absolutely be exhausting, especially because patients often end up having to research new treatments etc on their own. Sending you a gentle hug.

@sandhived6805 7 месяцев назад

Which tonic ? What followed in neuroplasticity? Please guide, thanks

@MignonetteGaspar 6 месяцев назад

Dear doctor what treatment is there fore a person with fybromyalgia and von willebrands disease.

@ArisConstantinidis-fd9kr 10 месяцев назад

What about chronic fatigue syndrome please 😊

@2ndChanceCrafting Год назад

I have h & BP. I have mild MCAS and I get almost instant infections from any insect bite-mosquito bites I get huge red inflamed area. I have always wondered about immune drugs and I wonder if any studies have been done, I figured probably as not ever heard anything about them. I am a retired nurse and ran our community support group. I sure they come up with something. They think my EDS-hypermobility & MCTD is what started my Fibro up. I have always been a "bendy".

@susanbunt8252 Год назад

I find that prednisolone lessens the symptoms of fibromyalgia and chronic fatigue. Sadly that comes with possible nasty side effects although I haven't had them fortunately. Have you heard of this before?

@Truerealism747 Год назад

Yes Dr Sarah myhill says this but says it's part with thyroid

@susanbunt8252 Год назад

@@Truerealism7471:07

@susanbunt8252 Год назад

I have Hashimotos . I think there is a link. Thank you

@janetphillips2875 Год назад

I tried mexotrexate with folic acid. No dice.

@pearlkally8325 7 месяцев назад

Does it work? Thank you

@auburnelectrologyskincare1167 Год назад

I have AS and sometimes think I have fibro. I don’t get cold I freeze, often my muscles when pressed on sting. I am more achey the joint pain.

@thefibroshow Год назад

Current estimates are that about 1/3 patients with autoimmune and inflammatory diseases like AS also have fibromyalgia. Definitely worth asking your doctor about it!

@Derek_Garnham 2 месяца назад

@@thefibroshow Not directly answering the original post, but the mention of AS and FMS caught my interest. I've had a condition that has been termed FM for 20+yrs, but initially my condition physically mimicked AS (Schober test, chest expansion measurements etc). This lead me to trial the fairly radical (at the time) no starch diet developed/promoted by prof. Alan Ebringer (kings college London) - my stiffness and mild/moderate pain improved within a couple of days, including bringing my chest expansion into normal range within a couple of weeks! 20 yrs on I have narrowed it down to avoiding all starchy food except potatoes, peas, beans and such, (I can tolerate a little rice but grains don't help at all). combined with standard self management of FMS - pacing, mindfulness, pain re-framing, and occasional visits from my friend Mary Jane. It's still there with a little FMS but hey, I'm 50+ and all my peers are really starting moan about aches and pains, whereas I kinda accept mine and get on with it happily enough. i get the feeling my immune system involved somehow, though possibly as a result of some process in my gut involving starch loving bacteria. Anyone relate?

@yorkshirerose6334 Год назад

You mentioned LDN with opioids. Can you take both at the same time and what doses? Thank you

@ShefNBama Год назад

I've been told no. The LDN blocks the opioid from working

@Truerealism747 Год назад

Nope apart from low dose tramadol

@thefibroshow Год назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-rK8rz19ySP0.html answers that very good question

@theselector2310 5 месяцев назад

So if antibodies can transfer fibromyalgia should fibro patients be donating blood?

@thefibroshow 5 месяцев назад

Great question! At this point there is no restriction to donating blood. The antibodies will be filtered out by the recipients body within a few weeks. It’s only if the body itself is continually creating those antibodies that symptoms would develop.

@cherrylwegner6292 6 месяцев назад

Any thoughts on Low Dose Naltrexone for use on fibromyalgia ?

@thefibroshow 6 месяцев назад

Yes, LDN can definitely help in fibromyalgia with reducing central nervous system inflammation. Check out my video on low dose naltrexone here ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-iDwouWXtztw.htmlsi=SoDDaAqv8NOgyr3o

@cherrylwegner6292 6 месяцев назад

@@thefibroshowThank you ! I also have Primary Evans syndrome and a host of other things I am hoping the LDN will help,,,,,,it's been a long road , and all uphill . Only one who suffers will understand !! cheers

@theantiqueactionfigure 5 месяцев назад

Anyone else have a flare up after the vax?

@PatMcIlwain-rw6if Год назад

Petrolia ontario name of clinic. Name of nursing home on murphy road sarnia ontario😊

@LouisWelker 2 месяца назад

I agree your clothes feel like sand paper. I feel like my bones are being crushed, I don't want people to touch me. The doctor's won't give you pain medication, but if they felt like I do, they would be swallowing tons of them.

@Jp-jv2tx Год назад

Very little information

@Derek_Garnham 2 месяца назад

Anyone else feeling real sorry for the mice here?

@VickiFrederick-s8c 5 месяцев назад

I can’t stand my clothing touching me!

@smileygirl1742 4 месяца назад

Bras are the worst 😢

@Derek_Garnham 2 месяца назад

being a Dude, belts are evil, but sadly necessary as my but seems to have shrunken so much. I'll notice that my whole lower body is "buzzing" until I re-adjust my waistband to sit a little higher than my tender spots. I feel braces (suspenders in U.S.) are on the horizon somewhere in my future but they'll probably set my shoulders off.

@smileygirl1742 2 месяца назад

@@Derek_Garnham Yes, it will be like a bra probably! You can’t win!

@Derek_Garnham 2 месяца назад

@@smileygirl1742 well, there is one obvious solution, though some people may object and it's too cold in the UK in winter :)

@smileygirl1742 2 месяца назад

@@Derek_Garnham Haha!