New Long Covid Breakthrough! First step towards a treatment?? Dr Gill

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New Long Covid Breakthrough! Inflammatory Markers Identified? Dr Gill
One of the major problems with long Covid, as we don't really know what is that is the underlying mechanisms behind the symptoms we're dealing with.
But a new paper for Dr Liew et al may have shed some light on this and allowed the identification of five different phenotypes of Long COvid
Here is the paper in question
www.nature.com/articles/s4159...
#DRGill #Longcovid #Covid
00:00 - Introduction
00:19 - Overview of the Study
01:05 - Importance of the Study and Its Future Impact
01:34 - Details of the Patient Group Studied
02:40 - Study Methodology
03:27 - Key Findings of the Study
04:05 - Why is Long COVID So Tough to Crack?
05:24 - Complement System Activation and Processes
09:07 - Complement System and Long COVID
10:04 - Future Treatment Directions
11:50 - Final Thoughts
13:31 - Closing Remarks

Опубликовано:

15 июн 2024

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Комментарии : 104

@AM_o2000 Месяц назад

As someone who has been disabled by ME/CFS for more than a decade, this video just gave me a glimmer of hope that the condition might be understood and possibly even treatable in my lifetime.

@slickrat Месяц назад

I think I speak for many that we still feel so bad for Diana "The Physics Girl" here on RU-vid, for her Long-Covid simptoms (being bed-bound for years). My heart goes to all people in a similar situation... (may studies like this one bring some hope)

@ronbunn1349 Месяц назад

@@neox6439usually people who study physics are not scientifically illiterate anti-vax types

@aarongomes314 24 дня назад

As a long covid sufferer I appreciate you providing us with some positive news - sounds like we are one step closer to a potential treatment. Please keep us informed of any further advancements. Cheers.

@borge2014 Месяц назад

A serious subject made easy to digest and visualize. Thank you! I can listen to Dr. Gill for hours.

@shelley7209 Месяц назад

I want a CURE not a test

@MyFriendPeter 29 дней назад

Post viral illness has been known about for decades to centuries. Unfortunately we are so far behind research and treatment that we are starting at the beginning of diagnosis. You can blame Drs for not treating the illness seriously or believing it. Government for misspending taxes on rubbish for people who don't deserve help. The pharmaceutical industry for not caring And the rest of the population shouting louder at their supposed problems for help. Berlin Cures seem to be the hope to look out for on their work of autoimmunity

@cocolamonte2458 Месяц назад

Amazing break down of the study, thank you so much. Excellent that you mentioned ME too as 80% of ME patients became ill after a virus or infection. I’ve thought for a long time it’s an autoimmune condition so I await more studies like this into LC with optimism

@georgewalford7027 Месяц назад

This was great, would love to see more like this.

@cuteface88 Месяц назад

Such a travesty what the professionals have done to us all. A real crime against humanity.

@dbulat 28 дней назад

Nearly 2 years of suffer. F This disease. Please, find a cure for that mess.

@Ytdeletesallmycomments 23 дня назад

Change dieet

@Iwoodlikethat Месяц назад

I liked this format and would appreciate more please

@Noellius2 Месяц назад

Unfortunately, insurance companies in the USA are starting to deny coverage of biologics for those of us who are symptomatic but without diagnostic tools to specify the mechanism that's going wrong.

@jamiew.2718 Месяц назад

++ for more paper discussions!

@keittomaster Месяц назад

Yes, real scientific and academic analysis on youtube! What a breath of fresh air!

@EdBrewster Месяц назад

Wow, thank you SO SO much for this, you explained it really well, and as a Long Covid sufferer myself, gave me a tiny bit of hope. You’re a legend, Dr Gill. Please explain more papers!

@VampyressVA 7 дней назад

Thank you for the amazing content. You are so witty and soft spoken, I could listen to you forever!

@gwilkins4617 Месяц назад

Keep the long COVID/ CFS vids coming!

@jamesbuerger9361 Месяц назад

My life will peak if I learn the cure for long covid via ASMR Seriously, as a person on medical leave from long covid, please do more of these!

@Nucl34r_W1nt3r Месяц назад

Very informative doc. Would love to see more like this !

@stoneblue294 Месяц назад

Thank you for putting together this video.

@msaditu Месяц назад

Excellent video! Very good information.

@helenhucker346 Месяц назад

Thank you very much Dr Gill and I would certainly appreciate more such videos. Does this latest research suggest that Long COVID has now become another autoimmune disease?

@Jay-bv4yy День назад

Great video!!! Thank you 🙏

@rosschambers1987 Месяц назад

Thanks for the interesting video. Does the same apply for those suffering with long term systemic illness similar to long covid but instead related to the medical intervention we all took? I am struggling with palpitations, exercise induced fatigue, brain fog/unpleasant sensations in my head, insomnia. I get a few good days but then get slammed back down. Trying HBOT at the moment and have previously tried so many other different things with no joy.

@saffire301 Месяц назад

Great job

@garnerblair5179 7 дней назад

With homocysteine being a marker for so many disease processes, i propose that MTHFR polymorphisms will make up the bulk of long-covid/vax sufferers. Also notable that even if you dont have a MTHFR polymorphism, you can mimick it with the modern/western diet .

@black.pinktrading5705 Месяц назад

This was so interesting, the explanations made so much sense even to someone who has zero medical knowledge ahah 😂 I would love too more videos like this in the future 😌😌😌

@TenkoBerry Месяц назад

This is Pretty Good Information 👌

@Gina-dn6xm Месяц назад

I had a research doctor in which I took a special blood test . I tested positive for high inflammation markers. The protocol included an AIDS drug and a steroid. The trouble here in the US , doctors can lose their licenses for prescribing off label drugs. After asking 5 doctors, I just gave up. The AIDS medication is an immune modulator. By the way, I'm mostly bed bound and home bound by extreme fatigue.

@lowandslow3939 27 дней назад

Was that Dr. Bruce Patterson and his team? I had tons of bloodwork done by his lab and also took HIV drugs off label. The numbers in my bloodwork improved but my symptoms continued until I got Covid for the second time. I’ll do one or two half days of work and then have to sleep for several days, all damn day and night. So sick and tired of being sick and tired.

@Gina-dn6xm 27 дней назад

@lowandslow3939 Yes, that is the doctor I was referring to. I'm sorry the treatment didn't work for you. I have heard that it works for some people but not all. I know what it is like to try to chase a cure, and nothing is working. I hope someday research can find medications that can help us all. But to be honest, I'm not holding my breath on that one. I've been sick too long, like you.

@lowandslow3939 25 дней назад

@@Gina-dn6xm Thanks for the response. I also believe his protocol helps many, but not all. I’ve pretty much accepted that this is my life for the foreseeable future. It sucks and it’s better than being dead, but not by much.

@Gina-dn6xm 25 дней назад

@lowandslow3939 I totally agree. I think I will be dead before they find medication that either cures us or keeps us in remission. The cruel thing about this disease is you don't die and you don't get better; you are a living, breathing, mostly bedbound person . The days turn into months, the months to years, and nothing changes.

@lowandslow3939 25 дней назад

@@Gina-dn6xm Another horrible aspect is that family members don’t understand and constantly tell me what they think, or heard will cure it. I’ve tried everything you can think of. I’m writing most of them off, almost wishing that just one of them would get it too, and validate my claims. My own mother tells me that if I don’t follow her directives, then I just don’t want to get better. She has no medical education but watches podcasts. Thanks mom but Ivermectin won’t cure it.

@user-fo5ic3nz6j Месяц назад

I coded twice in the hospital fighting for my life in ICU, life support, trak,intabated, total kidney failure and dyalises. Now my kidneys are working at 40%. I have had 2 ANA blood test done my number is 42. I hurt, I had dropped feet and feet stopped working and my left arm and left side of my face and had swallow issues while in the hospital, I can move my left arm and I am finally walking, but have limitations in my feet and legs, my hands and fingers are still problematic

@user-fo5ic3nz6j Месяц назад

I now have been diagnosed with COPD and Asuma

@hannafloyd Месяц назад

First thing I thought of was hope for Physics Girl ❤

@PurposefulPorpoise Месяц назад

Remnant Viral Reservoir. Thats my bet. Treatment will have to be similar to Hep C. Heat Therapy or some miraculous new anti-viral.

@rainerwein8604 Месяц назад

interesting it took the researchers such a long time to identify the blood as a related problem, though the acquired antiphospholipidsyndrome due to PostVac and PostCovid has been known since quite some years by now....

Месяц назад

I have had Long-Covid for over 4 years now, Dr Gill. The symptoms seem to be very much consistent with symptoms of Mast Cell Activation Syndrome, which is often hard to detect, diagnose and treat as well. Could there be a link between Long-Covid and MCAS in your view?

@MichaelMerritt 25 дней назад

I’ve had a lot of luck managing symptoms with oral sodium cromolyn (liquid 100mg bottle; start slow) and ivermectin 15mg every 3 days. Took me from bed ridden to functioning and occasionally able to workout. I’ve had LC for 4 years now. Not a cure but as close as I’ve gotten. Ivermectin helps reduce some of the cytokines and blocking prostaglandins which triggers mast cells. Helped a lot with brain fog. I hope you get well.

@Ytdeletesallmycomments 23 дня назад

Yes! Change your dieet. Fast Than omad Low histamine food No sugar and processed food Tulsi Quercetine Vit c d zink B Woodworm Charcoal Milk thistle Kurkuma After two days you will feel it. Go outside or sit on a bad day in the sun. Keep moving. Smile. Eat bad Crash Start over ...

@MJR1117 19 дней назад

Long covid isn't just one condition. It can be 2 or more. MCAS is one of the most common

@lowandslow3939 27 дней назад

I was a patient of Dr. Bruce Patterson and did a ton of bloodwork, consultations and meds, including off label HIV meds. My bloodwork numbers improved but my symptoms hit a plateau. After my second case of Covid, they worsened considerably. Are you familiar with his work? We knew more than a year ago that I have severe inflammation but not how to rein it in. I’m bed bound about 3-4 days per week. So tired of this.

@MichaelMerritt 25 дней назад

I’ve done the same with his protocol. My LC is strongly mast cell with some heart rate issues and mild dysautonomia. I’ve had some recent luck managing symptoms with ivermectin (blocks prostaglandins and reduces inflammation) and mast cell stabilizers like oral sodium cromolyn. Everyone is different but that has been helping me a lot.

@MichaelMerritt 25 дней назад

I’m still waiting to figure out how to rid of viral persistence if that’s the root of all this mess. Miraviroc wasn’t it for me.

@ground752 3 дня назад

I do wish a fix was possible

@lessons9745 5 дней назад

I got post infectious illness after I got a bacterial hospital acquired superbug infection in 2016 ..I have pots and who knows what else . have you heard of Berlin cures ?

@traianliviudanciu8665 27 дней назад

May be trigger is some IgM cryoglobuline ?

@Fliptheflipflop 27 дней назад

I've been hearing a lot about how it could be viral persistence, this would imply it's not an autoimmune problem right?

@DrJamesGill 27 дней назад

I think there are several processes. Clotting issue, autoimmune responses, histamine reaction, gut dysbiosis and viral persistence / reactivation The question is which are symptoms and which are causative

@Fliptheflipflop 27 дней назад

@@DrJamesGill thanks for the reply doc

@user-fo5ic3nz6j Месяц назад

I have lost of pain,I'm tired all the time, I am now medically disabled

@user-fo5ic3nz6j Месяц назад

Is there any chance of getting treatment or a way to help with my pain. I have anxiety and stress and depression. Have lots of painful inflammatory issues.

@Ytdeletesallmycomments 23 дня назад

Change your dieet. Fast Than omad Low histamine food No sugar and processed food Tulsi Quercetine Vit c d zink B Woodworm Charcoal Milk thistle Kurkuma After two days you will feel it. Go outside or sit on a bad day in the sun. Keep moving. Smile. Eat bad Crash Start over ...

@samir5118 Месяц назад

Hey doctor. When we eat meat, the stomach digests the meat. But why, when we are hungry, does the stomach not digest itself when it is made of meat?

@user-fo5ic3nz6j Месяц назад

I had Covid19 July of 2020 and came home January 2021

@wzupppp 27 дней назад

Is autoimmunity caused by wrong signals from the brain?

@user-tn8fd4xo8t Месяц назад

Two years long....so tired of this....

@DrJamesGill Месяц назад

Oh dear. I’m sorry you’ve had it that long. I do honestly believe we’ll get better treatments. We’re trying to use as much information as possible for our patients

@ArtTaggerr-223 Месяц назад

@@DrJamesGillI believe the key to understanding this illness is to compare those vaccinated to non-vaccinated, and the degree-symptoms of Covid long. Surely AI can help! The challenge is to get both sample groups to admit to ANY health changes.

@buppiano Месяц назад

Four years with diagnosed Long Covid, POTS, MCAS, Not vaxed. Could really use a cure so I can have a life.

@Ytdeletesallmycomments 23 дня назад

@@buppianoChange your dieet. Fast Than omad Low histamine food No sugar and processed food Tulsi Quercetine Vit c d zink B Woodworm Charcoal Milk thistle Kurkuma After two days you will feel it. Go outside or sit on a bad day in the sun. Keep moving. Smile. Eat bad Crash Start over ...

@traianliviudanciu8665 27 дней назад

High SARS COV2 replication will, theoretically,induce more inflammatory reaction. Did we know at what tissue temperature did SARS COV2 better replicate ? Why ? Because in 2020 at TWiV 659 at min29 virologist Christian Drosten suggest that SARS COV2 better replicate at low tissue temperature (35 -34C)

@wolfblood178 Месяц назад

ive had covid 3 times, i might now have it a 4th...

@sonrog8877 7 дней назад

The voice quality is so bad it’s painful to listen to. Any way to improve?

@user-fo5ic3nz6j Месяц назад

I have long Covid19

@danmarquez3971 Месяц назад

I say that long COVID is the result of exposure to COVID or COVID vaccines during a condition that increases IL-4 and IL-10. Why? These increase IgG4. So an ongoing allergy increases IL-4. Hypoxia increases IL-10. So the cure may be a reduction of LI-4, IL-10, and IgG4.

@danmarquez3971 Месяц назад

I also suspect that BanLec may fix IgG4 by making it trigger liver complement cascades.

@pauljarvis5384 Месяц назад

I have long baldness

@jamiew.2718 Месяц назад

Have you tried keeps

@kathrynletchford5114 Месяц назад

😂😂😂

@Bryce433 Месяц назад

@@shelley7209 yes

@jamiew.2718 Месяц назад

@@shelley7209 are you making fun of people with hair loss?

@shelley7209 Месяц назад

@@jamiew.2718 I’m happy you came to a site where people have lost their health, homes and way of life over baldness! Thanks for coming

@grahamcracker7129 Месяц назад

All that just to say… no one still has a clue what’s going on.

@snorgonofborkkad Месяц назад

What’s long covid?

@DrJamesGill Месяц назад

The definition is Covid symptoms remaining 12 weeks after initial infection, and here is the crucial bit, not explained by other pathology. In the long Covid clinic we spend a long time ruling out other things

@ArdGeal 9 дней назад

A vague set of symptoms attributable to people who enjoyed furlough so much they couldn't face going back to their shi**y jobs and wa*ker bosses.... be interested to see the stats for "long covid" vs jabbed and unjabbed status though....