I had the side effect of “insatiable appetite” from a mental health med that I must take to be stable and function. So, because of this I’ve been obese for the past 10 years no matter hard I tried, I would take my psych meds and then wake up at night and eat everything. Anyway, first dose of Wegovy and wasn’t hungry for the first time in over a decade, I’ve lost 47 pounds and joined a gym where I started strength training! I feel better than I have in ten years. My a1c is 4.9 and LDL 79. BMI 26!
Seroquel by chance? One dr I had gave me it for sleep. Off label low dose. It caused insane night time hunger. I would wake up 1 hour after falling asleep like clock work...and I'd be starving.
It's so disappointing when I see this daisy chained drug usage. It's like no one cares about solving the underlying issues, they just want to run away from the catalyst and treat symptoms. It's one thing if you have an organ that literally doesn't function, but mental health problems often stem from environmental issues. People will be poor, overworked, fat, depressed, and have no good relationships in their life. They'll then take antidepressants, obesity medication, food stamps, and jump on a dating app... They remain overworked, but humans can deal with a lot of stress, so minimize most of it and you'll be fine right? Then the occasional slight deviation from their medication schedule will lead to an episode that takes them right back to the reality they've been distracting themselves from with drugs, only to quickly cover it up again. Tension builds up and people do their best to bury it. Most do pretty well at that. The point isn't to say we shouldn't ever use a drug if we are in dire need. The point is that we need to pay closer to the overall patterns that are reflecting themselves in human behavior, and seek to solve the problems by fixing the environment, rather than treating symptoms that reinforce the current state of the environment. This can be done on multiple scales. An individual who has a tendency to overeat can remove junk food from their houses and shopping lists -- shop on the outside of the store or buy raw ingredients that force you to make a tray of cookies rather than buying them. Likewise, a society can collectively deem processed food as virtual poison, and take measures to make that reality known to the public. Instead though, all our solutions treat symptoms, and often one side effect will lead to another symptom. And at every turn, there's a guy and his middleman waiting to take money out of your pocket to "fix" your illness. A good portion of the time, the illness was caused by financial stress. Afterall, the correlation of income to crime, obesity, depression, and other diseases of despair are just waiting to start the next revolution, peaceful or otherwise. By accepting the treatments that capitalism comes up with for environmental caused illnesses, again, you reinforce the environment that led to treatments instead of cures. Every time you buy an anti-depressant, you feed the pharmaceuticals profit motive. If you are wealthy, mentally healthy, and emotionally healthy, but just can't stop overeating. Maybe it's because we design food to make you overeat. Maybe it's because you aren't eating food that's meant to be consumed by the human body in a natural environment. If you're wealthy, physically healthy, but you are depressed beyond imagination, maybe it's because some other aspect of your environment is failing you. Maybe it's not healthy or natural to read about the disgusting daily behaviors that 8 billion people living in a sick environments can muster in a single day. Maybe your empathy for other people's pain is trying to tell you something about your environment. But if you take an antidepressant to cover up the purpose of that empathy, what are you left with? Psychopathy? Why solve the catalysts of violence when you can find someone to build prisons and profit from imprisoning violent people? Why solve wealth inequality when you aren't personally effected, and can *probably* ignore it and get by to the end of your life? Why solve global hunger when the accompanying scarcity and strife is waiting to be milked for every dime by the military industrial complex? I don't mean to bash you for taking drugs that have helped you. I just want to point out that the pain you felt without these medications was not there by accident. That pain is an evolved response to environmental factors. If you cover up these natural responses, you inhibit your ability to solve the underlying problems. You may even inhibit your ability to see the problems at all. Your best course of action is to keep taking your medications, but be very conscious of *why* you need them. This goes deeper than simply saying "I was depressed/anxious and overeating." You need to seek out the original catalyst of the mental health issues. You need to understand that you did not solve your problems, you're merely treating them. With that fact comes a great responsibility to be aware of those symptoms as they show themselves in other people. You have experience that others who haven't suffered from the same illnesses don't have. This means you have intuition that helps you recognize symptoms of your mental health problems and food addiction when you see them in other people. You must both help others who you suspect suffer in the same ways, as well as *learn* from the similarities you have with those people. If you recognize a commonality among 95% of people with your particular mental health issues, then you've uncovered a potential catalyst. It's the original catalysts that we as a society need to focus on, otherwise the expectation is that we will all be lining up for our anti-obesity, anti-anxiety, and anti-depressant meds right after we get out of the bread line. In summary, obesity, anxiety, depression, crime, and other diseases of despair are on the rise. Wealth inequality is on the rise. Do not be so eager to treat your own problems if you don't understand why those symptoms are really there. Otherwise, you will find yourself somewhere down the road facing the consequences of someone else's problems. In the same way that you may have been disfunctional before your treatment while others looked down on you, is the same way you may look down at someone else for a different set of problems that stemmed from the same catalyst.
I'm a health psychologist working in bariatrics, non-surgical weight loss, and eating disorders in Jacksonville, FL. In short, I agree with this video completely and it is very well said and put together.
First time watching this guy. Hes spot on. Im so sick of everyone trying to look down on and make fun of bigger people for getting help they need to lose weight. Surgery is no joke and very hard. Everyone thinks its simple and a simple fix all. Its not. With the sleeve i lost 100 pounds. Put back on around 20 after a couple of years. My doctor got me on the shot and along with my sleeve doing really good. I hit my personal goal weight. The docotrs want about 30 more pounds off of me. Since surgery i excerise more, no sodas, pay attention to what i eat. I drink a protein shake daily and use it as a meal replacement. Like my doctor told me. You have to treat this like any addiction. Its a never ending battle.
My aunt was on it and lost 100lbs but built habbits to eat and due to feeling more confident works out daily now, she got off it and obv ate more but paired with her lifestyle changes she made on weygove she has kept the weight off and in fact even continued to lose 25lbs in 6 months post quitting. I love this video as it is super helpful and unbiased
@@scarred10 oh I agree but in reality most rely on the affect because their current poor food habits make them hungrier. If u do it right u don’t have to be on it forever but we both know 99% don’t Hahaha my aunt even said if she ate how she used too even on it her hunger was worse so as soon as she went higher in dose she cut out 80% of crap foods and she said it was night and day. Do that long enough ur body won’t crave food like it used too.
My dad is down 60 lbs on semiglutide. His A1C or whatever it's called is now in normal range, and his doctor just took him off metformin, a diabetic drug. I'm proud of him. He has sulfer burps as his worst side affect.
You not only provide the solid research, you also present it with maturity, wisdom, and compassion, all of which are much needed in the spheres of fitness and sports. 👏🙏🖖
I'm MD from Finland. Here semaglutide is primarly meant for type 2 diabetes patients who are obese or have unsatisfactory response to other diabetes medications. It is also compensated with tax money for those patients so it's easily affordable. However obese patients who don't have diabetes are willing to pay full price and suffer the side effects because it's so efficient. I wish people were that motivated to take all health improving medications I prescribe them.
Wegovy is specifically approved for weight management. It’s the exact same drug as Ozempic. As an MD you should be aware of the updates in these drugs, whether they are available in your country currently or not. Your comment comes off as extremely judgmental and condescending towards obese patients - many/most of whom have struggled for decades with weight loss. Do better, doctor.
I appreciate your pragmatic approach to this (no surprise). As a fitness enthusiast, health care provider, AND type 2 diabetic myself (since childhood), I think I have a reasonable perspective regarding the right types of patients who might need these meds. If they're at their wits-end with trying to lose weight and are clinically obese, it's kind of ridiculous to not try it for them (with guidance regarding other levers they can pull too) and could be the kick start they need to get started down the right path. It's nice to see you have an "in the right person and in the right situation" view on the GLP-1 agonosts!
I fit in that category. I'm hella fat and need to drop like 200 pounds to be considered a healthy weight. I was prescribed Wegovy but the cost for me due to my insurance is way too much, over $1k a month for a few months. Hopefully I can change my plan later this year and my employer will still cover it. I feel like a lot of people aren't trying to change their eating habits while taking semaglutide so they will just gain it back once they are off the medicine.
Like all fat people that have tried to lose weight, have lost weight, only some lose as much as they want. I guess it's a battle and by the time they get the weight off they are mentally done and can no longer control the urges. If the fight was easy, they should not so mentally destroyed and could go on a plan to build the muscle back and keep the fat off. Nobody really talks about what to do when the fat has been lost and the program to go on, to fix the metabolic adaptation. To me it's about lifting weights and training super hard, but not too long or often. If that is less excercise than you were doing during fat loss, you don't need to eat more straight away, but gradually eat more as metabolism increases. If you are building muscle at a reasonably fast rate, metabolic adaptation will be reversed in under 2 months. I finished a diet 6 weeks ago, because my blood pressure had got too low, now I am finding it hard to eat enough.
Agree with your view. Some people just think they found a magic pill. I’m sure they are still hitting the fast food drive thru, hitting the bars but not hitting the gym.
"Try" it? It works but as soon as you quit the weight comes back. It's a lifetime commitment because people can't eat better and exercise more. Improve your discipline, improve your life.
It's designed to change the eating habits. It teaches that eat not enough you wont loose a thing, you need to eat. If you eat "bad foods" you get punished by feeling sick, and explosive toilet time. Or the polar opposite.....If you eat high protein low fat, you feel fine and it also shows on the scales. You typically will go through one or several periods of platau so they tend to look to diet/exercise changes to work out why, for the price people want it to work. For this reason I feel the cost should be high. It keeps people accountable and on track.
Great take Layne! My Doc has me on Ozempic, 6 weeks in. We decided to use it to help me get to a weight for surgery on my knee. Really hard to work out more if you have a wrecked knee and simple mechanics like walking are a challenge. Since day one, I have worked with my PT and nutritionist on the "reversing" off the drug. The lifestyle change is really important. It's disappointing that many chase stuff like this as a wonder "drug" and do nothing to change their habits for longer term success.
I love your nuanced take on this that considers both the scientific data and the personal aspect regarding mental, emotional, cultural, economic, and societal factors surrounding obesity, satiety, and appetite. Also you never get hung up on the aesthetics or societal implications of someone's weight. It's always based around the factors like diabetes, heart disease, etc. That being fat doesn't make you a bad person.
Appreciate the insight. I'm on Mounjaro, and have been for about 4 months now. Re-gained all my weight after gastric sleeve - mostly because of lack of discipline. I also suffer from chronic depression in that my dopamine response is very inhibited. The reason why I mention this, is because junk food (for me) triggers that dopamine response that my body craves, and it's extremely difficult, especially in deep depressive episodes to resist the urge to eat bad food or drink alcohol. Enter Mounjaro. Thanks to this medication the urge to consume bad food is nearly zero. I've lost 30 pounds and this has given me the energy and determination to go back to the gym again. I'm so thankful for this medicine and really do think it's critical for those like me that need help resisting the brain chemistry that promotes bad habits and junk food addiction. Would really like to hear your thoughts on insulin resistance as well. Cheers!
@@youngkimmy40 A friend was getting it for $25...and was sent a letter - SURPRISE - won't be $25 anymore...up to $1200 or whatever the full price is, so she has to stop. Sucks.
I'm on Ozempic for a high fasting blood sugar and high A1C. It's not only helped me with my fasting BS, went from 131 to 98, but helped me drop 15lbs. I hope to keep going with the weight loss and I hope, to get off it someday.
I’m an ER physician and my hospital system just started giving this out for weight loss within the past year. I have seen several people in the ER for intractable nausea and vomiting with pretty severe abdominal pain. Granted I get filtered people with the worst responses, just something to keep in mind. Side effects can be pretty bad.
@IblisTheMage I'm a paramedic and people go to the ER because a tree leaf fell on them. You learn how ridiculous people can be in the Healthcare system.
@@Nerdybdirty First time I read it, I read "because a tree fell on them", ok that makes sense... then I read "tree leaf"... wut?????? 😀 😀 😀. When I was a kid, going to the ER meant stiches, arm in a sling, or a gypsum casket... 😀, And for sure a tetanus vaccine, no matter when the last one was 😀
Great to hear you talk about this subject. I struggle with weight but the side effect that wasn’t mentioned and scares me away is the gastrointestinal paralysis
Thank you for being so open minded and understanding. This drug is a game changer and is very helpful to anyone who has been struggling with obesity for years. It’s not the ultimate solution but emphasizing personal responsibility is vital.
Semaglitide and Terzapitide were being sold by research chemical companies for a good bit before the patent hit. Was being sold for about 1/10th of the price. Works amazing. Big pharma loves the profits though
I was waiting for this because my doctor said no to me as far as weight loss drugs go. She told me drugs don’t change habits . She told me I need to reset my brain and work on my diet. I want to lose 25-30 lbs . Plus I’m on Prozac. She said I simply don’t need it . I used adipex years ago lost the weight, and regained it all back plus more. I had no plan post weight loss. Thank you for sharing your knowledge
You should thank your doctor. She is giving you good advice. Wait to see the outcomes of this drug in 10 yrs. Side effects of gastroparesis. Serotonin is made in the gut so its production is down regulated increasing the risk of suicidal ideation. Focus on eating whole foods and exercise.
This was a great summary but with one omission. The weight lost with these drugs is a much higher percentage of lean mass vs fat when compared to a standard lifestyle, exercise, and diet regime. Also there is a tic up in heart rate. So the pros and cons need to be weighed carefully, particularly with adolescents. Long term studies need to be done to assure of no long term negative effects. That said, the scales tip in favor of those with difficulty in managing severe metabolic syndrome. Key is to be informed.
I have about 150lbs to lose and a prime candidate for this. But you’re right, insurance doesn’t cover it although I’m classified “pre-diabetic” and obese. My search continues however I’ve hired a coach for 12 months to assist with establishing good habits to lose weight and maintain it.
Thanks again for another nuanced look at a topic, Layne. Today I have finally reached my "maintenance" threshold goal after losing 140 lbs over the last 14 - 18 months. Gonna rewatch your videos on fat-loss and maintenance to make sure I don't mess things up.
@@sufiblade IMHO lifestyle modification must be at least a part of the treatment regimen, in some cases - the only one. But in others, when it's tried and not effective, ozempic or other meds can be used.
The reason health insurance is reluctant to pay for drugs like this for weight loss is bc A) the weight loss is temporary/tied to continued use of said drugs (which are expensive to begin with) and B) there is no guarantee that your current health insurance company will be the beneficiary of the health benefits/reduced long-term costs associated with the weight loss, as people change jobs and/or insurance companies all the time.
I was listening to the Mind Pump guys be quite disparaging about it, but they do come from a hyper-masculine, chest beating area of the fitness industry where nuance is often lost on them. Thank you Layne, for coming in with a balanced, sensitive approach to this hugely important shift in the fitness/health world. I myself have been obese, underweight, a healthy weight and now, trying to lose that last 14lbs that love to sit there, laughing at me. I couldn't afford to buy Ozempic, but even if I could, I probably wouldn't touch the stuff - a calorie deficit and lifting weights works for me, but I have crazy self-control when I put my mind to it. Most people don't have the level of self-control I do, so shouting 'get a trainer' or 'eat less move more' isn't going to solve the issue. One massive, perhaps insurmountable issue is the systemic problems Western society has with its food. Highly palatable processed food, I believe, is hugely responsible for the obesity epidemic. Until 'big food' get on board, we'll always be looking for 'big pharma' to provide the answers (at a cost).
I’ve added semaglutide to my nutrition and training planning 4 weeks ago and was wondering - “what would Dr. Norton say about this?” I’ve read your book 2x listened to many many many videos. I’m impressed yet once again how you don’t “sell out” you could have easily pushed this aside and made it sound like it’s a waste of time. Appreciate you much. Eat less move more works - kinda👊🏼
Thanks Layne. My father is obese and is one of those old school guys who IS NOT going to workout and eat right. I’m going to tell him to talk to his doctor about this.
Well said, I spoke with a friend who started taking ozempic or something similar and I said the exact same thing, injections without changes to lifestyle (this person doesn't work out and eats junk food) and you'll relapse, good to hear from a reliable source that this is generally safe.
Thank you thank you thank you for this. You are one of my most trusted resource in science based approaches to sustainable weight loss and was very interested to hear your take. Maybe I’m biased because I agree with this, but glad to hear your thoughts all the same. 😊
I've become somewhat of a naturalist. Never thought I would be one, but here I am. Humans want to be healthy, at least the lizard brain prefers it. This means humans don't want to be obese. But it also means humans want to be mobile, they want to eat healthy, they want healthy relationships, a healthy economy etc. I believe all of these things work in sync with each other. In other words, if your environment is working for you, you will work for you... If your environment is healthy, you will be healthy. However, when your environment is not working for you, for example, an economy that forces you to work 60 hours to get by, you're not going to want to put in the effort to fix obesity for example. I'm tired of people saying "95% of diets fail," as evidence to take the easy path of weight loss surgery or medication. The reality is that the struggle you endure to become the 5% is dependent on you fixing the environment, both mental and physical, and by extension, all the other issues that present themselves in your environment. If you just treat one symptom of the poor environment, then not only do you not solve the underlying issues, but you become dependent on the very environment that created the weight loss pill. That environment is filled with greedy pharmaceutical companies that want nothing but to put you on another drug for life. Using a statistic to write yourself off just manifests your expectations before you've even given it a fair shot. In fact, I would argue the statistics itself removes the fairness from your attempts altogether, unless you truly and honestly believe the statistics don't apply to you. This is a very hard thing to do, and I very few can achieve it. I'm a naturalist because I believe in solving underlying problems. What happens when supply chains get disrupted or your insurance stops covering weight loss medication? What happens when some unforseen side effect hits you 2 decades later?
I have been on Rybelsus for 4 months, and the control of hunger has been amazing. I have lost a total of 60 pounds. I would like to lose as much weight as I am able to lose safely. My health, energy, and my ability to work out have all improved. I am 59 years old and i feel so much better. I would like to get as lean as possible. Food tastes great, but i have found I eat much less on Rybelsus. I feel satisfied, and stepping on that scale losing another 2 pounds is highly motivating.
Finally a take I can agree with. There seems to be a ton of fear mongering surrounding GLP-1 agonists. Not everyone can just "eat less". This helps those people.
Thank you for saying this! The drug helps you eat less. It's not what makes you lose weight. Eating less calories, making better food choices and exercise is what really does it. It has calmed my food brain so I'm not thinking about food all the time. And of course weight will come back when you stop it and go back to your "normal" way of eating.
You are supposed to stay on it for life,not come off since its for people who've failed on conventional methods.Exercise does very little to lose weight,its how many calories you eat and the drug reduces that.
Absolutely! I believe discipline involves a variety of behaviors that are not always generalized across settings and events. It’s never too late to expand our learning repertoires. These medications might bring people into closer contact with those positive results which reinforce good health behaviors, thus making it more likely folks will follow through with nutrition plans (I.e., it seems possible these meds can help promote/increase good discipline, if played right).
The problem with appetite suppressants is that most people don’t overeat because they feel hungry. Most people overeat calories because they eat calorie dense / nutrient poor foods, and mindlessly eat out of habit and boredom.
Great timing for this vid, heard a lot about this drug recently and was wondering how it worked, what the side effects were, etc. Sounds like it could be a game-changer for a lot of people in the battle against diabesity.
I was able to get my Wegovy approved based on conditions related to Metabolic Syndrome (BP, Obesity, Cholesterol, Family History) so insurance coverage is improving somewhat. I am very focused on the “after” and now that I’m within 15lbs of my goal weight, am looking forward to slowly reverse dieting over the next year and weaning myself off of the drug.
One of the best videos I've seen on the subject. Seems to cover major questions and provide good answers without going into deep or excessive details ... a good summary for most people on the subject. Another thing not usually covered is effect of stress of being hungry by reducing calorie intake, on hormones such as stress hormones, which after a lengthy time, might be considered chronic stress, and the effect on a person's general health that is trying to lose weight for health purposes with a low success rate.
This is great advice. Not everyone can grind and we all have areas where we are less disciplined. This should only be prescribed as a kick start to weight loss to motivate people. We have to implement the healthy habits in order to be successful in the long term. However, I find that most people just want to take it as a shortcut so they don’t have to work too hard. They love their highly palatable food and will go back to eating large quantities of it when they stop the drug…
I'm glad it's a prescription drugs. I hated that I needed caffeine to curb hunger towards the later weeks of a cut, and the feeling of knowing you can accomplish weight loss through determination and will power alone is something everyone should experience at least once in their lives. I hope this drug won't take away from that.
My appetite is insane. The amount of food I can put away is disgusting. Since I’ve started GLP-1 (Sema), I routine eat at or lower than 2,000 calories. Sema has worked miracles for me. Not trying to promote it and definitely speak to your doctor about it but it is a POWERFUL appetite suppressant.
I've seen some doctors comment that their anecdotal experience in watching patients is that it helps patients who eat because they're hungry all the time, and has minimal effect on patients who eat out of habit (e.g. boredom, to deal with emotional issues, etc.).
It's an over-simplified view, but I sort of look at these drugs as resetting appetite levels to an average population level, not as some cheat to avoid hard work. That said -- it'd be nice if these drugs in an obesity setting were always accompanied by lifestyle changes, since just reducing the amount of hyperpaletable food you consume will probably keep you on the drug forever, instead of eventually being able to at least reduce the dose if lifestyle changes were in place as well.
Another great video. I was thinking the same thing, for someone that in clinically overweight, it could prove to be a great tool while they focus on building the habits. One of my biggest worry would be, some people not getting in enough nutritious foods while taking it and then neglecting the habit of eating nutritious food, simply because they are just not hungry enough.
Gastric sleeve teaches nothing, this does. If you dont eat it stops working, some even gain weight. If you eat bad foods, it causes discomfort from feeling nauseas to it being rejected and vomited up, or very bad toilet experiences. But if you eat high protein low fat it will show in your energy levels, you feel "normal" and continue to loose weight which is only supposed to be a kg a week. Slow and steady and consistent is the goal. It also requires that you drink more (well to the standard recommended amounts) People not only loose the craving for sweet or salty foods as the insulin is more stable but it tends to make people enjoy or like the taste of things like coffee, alcohol cigarettes even medical and recreational drugs like weed and lots of people find that they use less medicines that are used in non scheduled treatment aka less use of valium, xanax is used to combat peaks in anxiety etc. Some people talk of it helping them stay sober off narcotics and stimulants. Its quite pavlovian to begin with and the 'education' comes in a physically form. Kinda how alot of over eating or bad foods and dopamine form habits before, Now you get punishment, and are not loosing like everyone else on the treatment. I do believe the community and group support pages are absolutely necessary for the encouragement and advice and suggestions and ideas. Most will experience plateaus and this causes people to look into their diets and exercise habits as its too expensive to just take and wait until it ends. When correctly used it should be done with a reverse of the introduction dosing process. So a weekly or incremental decrease so that the body and you can adjust and change your habits accordingly. To relearn the hunger curs and sensations and what helps to keep them at bay.
I've qualified for ozempic for weight loss. In Canada, disability will cover the cost. My Dr will be prescribing it once my sleep related anxiety has been resolved. Thank you for the positive video!
I'm pre diabetic...58 years old. Been obese and dieting all my life. I stay hungry...I can't understand. My Dr prescribed this medication to help but my insurance does not cover it! This is the problem...especially when I would benefit from this medication. It sucks. I pretty much have to have full blown diabetes to get covered. I'm still eating healthy and losing slowly but it's a struggle. I just want to get to a healthy weight for once before I die. Taking one day at a time. Thank you for your info!
Working on a podcast about this stuff/theme as we speak, glad to find another voice in the world that sees it the same way: medications can be effective, but without lifestyle/mindset modification, its a bandaid on a bullethole. Cheers!
Great video. Prevention will be less expensive than treating all of the conditions that result from obesity. I am looking at whether I want to try Ozempic. I'll talk to my doctor and we'll decide together. If I do go on it, it's going to be as an adjunct to what I'm already doing to lose weight. I'm working on changing my eating habits and some help along would be good.
I have tried semaglutide for over 5 months starting 0.25mL and 1.0mL at last 2 months. and lost no weight. at 98KG. with all the side effects and everything. I am not saying it doesnt work ,but it is not for everyone.
@@GamoXVI yeah I wish it could help with that. To be honest I’m pretty good at eating healthy when I’m cutting weight but it does become tiresome feeling hungry all the time so I’d love to give semaglutide a shot if it would help with that.
I took Wegovy 18 months ago and lost 35 pounds (15% of BMI) I did not change a THING but then put most of it back on over the last year. I am going back on now but I am recording my food and plan to get a personal trainer. Hoping this will help me change this time.
Really like your comments about discipline. Everyone lacks discipline is some aspect of life; for some people, it's in their food intake. Great video, thanks for discussing.
Thank you for this. I'm almost 5 months in. I've just now lost 20 lbs. I seriously could not have done it without a calorie deficit and walk 7 kms a day. Nice to hear about it being in this format. 😊
The modification of behavior is super important. I have a family member who literally lost zero pounds on the drug for a year, because she did not change a single behavior. And now she's saying the medicine doesn't work. So, I feel above all habitual additions to life, exercise is so important, even if it's just for the health of the brain.
Hey, I really liked your collaboration with Jeff Nippard and so I came over to check you out. Leaving a comment for the algorithm and to let you know I love these analyses/mythbusting videos so you've got a new sub.
Really glad to see your end conclusion. Though I understand ideas of personal responsibility. It simply seems to be best for the overall good and at the end of the day for insurance costs etc. to use it when it MAKES SENSE to do so. Great video.
I lost 30lbs in 3 months and got skinny fat. I gained it all back in like 3 weeks. I think it’s great for people who are really heavy and need a boost. Not so much for bodybuilding. That’s my take on it. Great vid Layne.
Sounds like your dose was way too high. It's not good for anyone, heavy or otherwise, to lose >5% of their bodyweight in a few months. Muscle loss is almost guaranteed at that point
What are your thoughts on GLP-1 agonists possibly causing you to lose more lean bodymass compared to an isocaloric state without GLP-1 agonists? Kevin Hall recently responded to a tweet in which he explaines why this could be true. I'm actually a really big fan of GLP-agonists, I think they are a great weight loss tool for people who have a hard time sticking to a low calorie diet because of a lack of satiety. However I also think it's important to look at the possible risks.
Great question. I saw a short video clip in which Peter Attia claims the majority of fat loss from these-type of drugs is derived from lean body mass rather than fat. Like 2/3s to 1/3. Still getting the "weight loss," but I'm not sure it's favorable to maintaining much lean body mass.
I would guess it is most likely because when someone has a crap diet, and you simply reduce their appetite. They still have a crap diet and just eat less of their crap diet. When someone does a correct lower calorie diet. They usually improve what they eat with more protein and often incorporate a basic exercise program as well which would reduce the % of LBM loss.
If you maintain resistance training and adequate protein intake, there's no reason to believe any lean mass would come off. The hard part may be to actually take in enough protein when appetite is suppressed.
@@wldtrakI think studies actually show that it's around 1/3 which is still more than without the drugs. At the end of the day I think it's still way better than not losing weight because it still improves body composition.
Thanks for the video. I really don't understand insurance companies policies. Would they rather pay the 12 grand a year for this drug or the 100k+ hospital bills from heart attacks etc
The majority of people that ask me for advice on losing weight, refuse to calorie count when I suggest it. When they hear "eat less", people often think in terms of quantity not about calories. A few years ago, I switched and started telling people to "eat more" and a higher percentage of those people are losing weight than ones I tell to "eat less" They have been told to eat less their whole life and don't want to hear it again. I use a tone and wording to make it sound like its a special trick nobody knows about. "I'm going to make you a deal, I'll show you a way to eat more and still lose weight" "you are correct there is a catch, you will have to stop buying anything that's high sugar or high fat" "your fridge and pantry are still going to have a huge selection in them and you can eat all you want" You find what lean meats, fruits, vegetables, and complex carbs they like to eat, starting with that and each week give them a few new suggestions for variety. This will feel like common sense to the majority of this audience & my sample size isn't huge but the results are good so far.
