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Parkinson's Disease Drugs 

Ninja Nerd
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Official Ninja Nerd Website: ninjanerd.org
You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
www.ninjanerd.org/lecture/par...
Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Parkinson's Disease Medications. During this lecture we will start by reviewing the Basal Ganglia Anatomy and Physiology. We will also be reviewing the direct and indirect pathway that is affected with Parkinson's disease. We will then transition into the various drug categories used to treat Parkinson's which includes Levodopa or L-Dopa, Dopamine Agonists, COMT inhibitors, MAO-B inhibitors, Amantadine, and Anticholinergics. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Parkinson’s Disease Medications Introduction
1:20 Basal Ganglia Anatomy
4:23 Direct vs. Indirect Pathway
18:23 Pathophysiology of Parkinson’s Disease
21:26 Drug Classes for Parkinson’s Disease
24:36 Mechanism of Action
38:51 L-Dopa + Carbidopa
1:00:22 Dopamine Agonists
1:06:08 COMT-Inhibitors
1:11:39 MAO-B-Inhibitors
1:20:12 Amantadine
1:27:10 Anticholinergics
1:31:18 PD Medications - Practice Problems
1:36:13 Comment, Like, SUBSCRIBE!
Supplemental Lectures:
Basal Ganglia - • Neurology | Basal Gang...
Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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/ @ninjanerdofficial
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SOCIAL MEDIA
FACEBOOK | / ninjanerdlectures
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TWITTER | / ninjanerdsci
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#ninjanerd #parkinsonsdisease #pharmacology

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5 июл 2024

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Комментарии : 187   
@aneesazafar9646
@aneesazafar9646 Год назад
You are remarkable, I have never met a teacher like you.
@smoovlatino
@smoovlatino 7 месяцев назад
I am speechless at how gifted you are in teaching. We must protect this man.
@HarshPatel-he2vh
@HarshPatel-he2vh 2 месяца назад
From whom? no one hates him😭
@silviamontisci6399
@silviamontisci6399 Год назад
Italian medical student here! I'm glad I found you on YT, you're such a life-saver. Thank you for sharing your passion for these subjects, you're amazing man! (and your staff too, of course)
@deerfashion
@deerfashion Год назад
Starting an assignment on PD meds for my pharmacology class today! SO perfect!😍
@Lotus-iz3ic
@Lotus-iz3ic Год назад
Actually I've been struggling with Parkinson's drugs and mechanisms as I used to hate pharmacology the first medical year in college but this video definitely make it way too easier , I am really feeling grateful, thank you a lot ❤❤❤❤ you are the greatest 💪🏻
@faiza.m9974
@faiza.m9974 Год назад
Amazing this video save me, I spend many days to read textbooks and watching my lectures and I feel so dumb but now this video is totally make sense to me and put everything I’ve read together, thank you so much 🎉
@niharikasaraf3506
@niharikasaraf3506 Год назад
I never bothered learning WHY we used COMT and MAO B inhibitors before this video, damn thank you!!
@khalilahd.
@khalilahd. Год назад
So helpful. Thank you! ❤
@tanveerabdullah3297
@tanveerabdullah3297 Год назад
Kindly make videos on antidepressents and anxiolytics ...plz
@madisonwatt329
@madisonwatt329 8 месяцев назад
Your videos are amazing! Clears up so much information left out by professors! Thank you for everything you do.
@direxsama258
@direxsama258 Год назад
didnt watch this yet but without doubtes i know it will be a BANGER Thank you Dr
@ella-meow1116
@ella-meow1116 Год назад
please please continue making pharmacology videos ,as pharmacy student i find these so helpful thank you for your effort
@AnnMulvihill-lt9qz
@AnnMulvihill-lt9qz 10 месяцев назад
You are Excellent. Great teacher. Thanks from retired RNBSN with Parkin sons. Still with thrist for knowledge to understand. Thanks.
@yvonnevillalba7722
@yvonnevillalba7722 Год назад
You truly are the best teacher ever! Thank you for this video.
@chinnyogbonna6506
@chinnyogbonna6506 Год назад
I love your passion and teaching, always amazed. Thank you very much.
@s_l_m__
@s_l_m__ Год назад
Extraordinarily well made video. Thank you, Zach
@steveh1460
@steveh1460 Год назад
Love your passion for teaching! Thank you!
@sadiajafar5792
@sadiajafar5792 Год назад
I love the way you you teach I think your are the bestest teacher in this whole world 🌍
@faisalqasmi9543
@faisalqasmi9543 Год назад
Be healthy sir 🙏 we really need you
@leticiadermith9832
@leticiadermith9832 28 дней назад
You have a gift and I am so grateful for your existence on this earth and time.
@ayanafrancis6294
@ayanafrancis6294 Год назад
You are a saviour .Thank you zach🔥
@kathikloeckner6118
@kathikloeckner6118 Год назад
I love your memory and your passion! ROCK STAR!
@francescacovre7526
@francescacovre7526 Год назад
You are my saver for any exam preparation
@jis2937
@jis2937 Год назад
I’m grateful for your existence, you do matter & we appreciate u
@monkearmy2216
@monkearmy2216 Год назад
I really like these videos, hope you get more recognition
@mmsah30
@mmsah30 Год назад
i love u man, u made it easy on me to understand the topics
@biybimaryamjoldasbaeva506
@biybimaryamjoldasbaeva506 4 месяца назад
Thanks a lot for the perfect lecture!
@mariapereiramd7173
@mariapereiramd7173 Год назад
Thank you for this video!
@robinkaczanowski7970
@robinkaczanowski7970 8 дней назад
Love this❤❤❤❤Need more! Excellent Teacher.
@mmdohhmod7622
@mmdohhmod7622 Год назад
You are awesome teacher, Man... Thanks for everything
@user-sb7rs4tp2l
@user-sb7rs4tp2l 7 месяцев назад
we need more pharmacology videos
@SH-eh6wx
@SH-eh6wx 4 месяца назад
God bless you in the ways you do not even imagine!
@kda-2672
@kda-2672 2 месяца назад
Thank you so much ninja nerd❤ you're a life saver
@fallenangel8785
@fallenangel8785 Год назад
you are a great human being
@mohamedkhyrat7372
@mohamedkhyrat7372 6 месяцев назад
Thank you so much for everything❤
@irereomio1797
@irereomio1797 2 месяца назад
Love love your videos. Thank you
@dindaire
@dindaire Год назад
Omg thank you!! I take my PANCE in a few weeks and your videos are so good
@katarinatysse6086
@katarinatysse6086 10 месяцев назад
Thank you so much!!
@emacroitor1053
@emacroitor1053 Год назад
thank you for your help! I am grateful! 😇
@malikihamski4265
@malikihamski4265 Год назад
Sir I appreciate your work Thank you so much A love from TANZANIA.......!
@sangsenglay9989
@sangsenglay9989 Год назад
thank you so much sir, may god bless u
@ricardor2166
@ricardor2166 11 месяцев назад
Great quality
@laureenl6840
@laureenl6840 Год назад
Great video! It answered almost all of my questions. The only question remaining is, why is it so important for Parkinson’s disease drugs to be giving at specific times with little to no goodwill time? Does it have to do with the effective time?
@stephanieslay2976
@stephanieslay2976 Месяц назад
I can't thank you enough for this video 🙏 You're just awesome ❤
@wombat2379
@wombat2379 Год назад
great job!! Thank YOu!!
@oscarpaz6162
@oscarpaz6162 2 месяца назад
thank u so much for this video zach 🥰
@chipochuumpu6602
@chipochuumpu6602 9 месяцев назад
Thank you!
@ahmedfathi3217
@ahmedfathi3217 Год назад
I love your videos. Definitely one of the best out there. Also, nice glasses 🤓
@mariakara4848
@mariakara4848 8 месяцев назад
the best teacher ever🌹
@vetnet100
@vetnet100 Год назад
Nice video. Helpful and informative
@obvankinndy7063
@obvankinndy7063 Год назад
Antiparkinson's drugs and hypnotics vids are on time, if only the antipsychotic drugs are on the list it would have been just geeat
@rmurthy5011
@rmurthy5011 Год назад
Very informative. Learnt a lot even as a geriatrics doctor. Perhaps include apomorphine in the drugs? Confess I love your explanation so much I don't want to go back to the books for that!
@ladydeebigandcute2681
@ladydeebigandcute2681 Месяц назад
Let this man open his university ❤
@kirandeepkaur6265
@kirandeepkaur6265 2 месяца назад
Great teaching process👍🏻👍🏻👍🏻👍🏻
@asmakhalid8873
@asmakhalid8873 День назад
Thank you so much💕
@goosey1055
@goosey1055 5 месяцев назад
Excellent video.
@universeusa
@universeusa Год назад
You are one of a kind 👏👍
@hubb4manu
@hubb4manu Год назад
Thank you so much.
@jesuschaudhary5458
@jesuschaudhary5458 Месяц назад
Really amazing ❤❤!!
@ellionorader3219
@ellionorader3219 Год назад
Thank uuuuu best teacher ever I used to follow You when the channel has some 70k so soproud that you ve reached the M You deserve mooooore
@iulianaandra9699
@iulianaandra9699 Год назад
Thank you!❤
@NishitaKinger-hr4ec
@NishitaKinger-hr4ec 5 месяцев назад
Great Work!
@maalusn934
@maalusn934 10 месяцев назад
Thank you so much❤
@ranlove47
@ranlove47 Год назад
As always another great video. Wife recently diagnosed with Parkinson’s. Been doin a deep dive into high does of B1 (thiamine) for treatment. After adding it to the treatment made a huge improvement over the meds (Rytary $$$$$). Would love to see a deep dive into why/how this mechanism might work. Most doctors don’t know or haven’t heard of this treatment. Obviously no money to be made on a vitamin. Thanks again for you dedication.
@steveh1460
@steveh1460 Год назад
That would be a great topic to cover!
@armelagjini
@armelagjini Год назад
you are the best! god bless you
@rajejyo
@rajejyo Год назад
A quick question...does ADR's in brain happens due to excess dopamine? as dopamine cannot cross BBB and if yes, then how does ADR's happens in mesolimbic pathway
@NinjaNerdOfficial
@NinjaNerdOfficial Год назад
Great question. Any drug that increases synthesis of dopamine, prevents breakdown of dopamine can be utilized in dopaminergic pathways in the brain i.e mesocortical or Mesolimbic pathway etc
@michaelibrahim7190
@michaelibrahim7190 2 месяца назад
The reason i will be a Pharmacist will be bc you exist! You are much loved in England
@amine6005
@amine6005 Год назад
You are the best of all the time in saving med students life we are craving for more pharmacology
@hilinatakele5021
@hilinatakele5021 4 месяца назад
Thank you so much
@tolika7979
@tolika7979 Год назад
Hello, I admire your job well done, it is very helpful for all of us! I watch you regularly and learn new things! Thanks! I'm doing a doctorate! I am looking for a connection between impaired understanding of human language, more precisely decoding, in patients with Parkinson's syndrome! What can it be, and where does it come from? Help!!! Be healthy and happy 🙂
@Abdullah_DS
@Abdullah_DS Месяц назад
You know Zach that your vids are kind of entertainment!
@ashutoshsahoo1013
@ashutoshsahoo1013 8 месяцев назад
Finally All concept clear 😌Salute to your Passion and Strength. Love from Odisha.
@Gandalf-DZ
@Gandalf-DZ 11 месяцев назад
Gotta love this dude
@fatimahthely7040
@fatimahthely7040 3 месяца назад
Thank you ❤
@norasaf7838
@norasaf7838 Год назад
The best Ph of medicine
@hotgamer0609
@hotgamer0609 2 месяца назад
Thank you sir
@nidallkl8559
@nidallkl8559 Год назад
keep doing this thank youu helps a looot
@zainabfarooq5263
@zainabfarooq5263 Год назад
I comment for you before I watch the lesson because I’m sure you are great
@mohsward4708
@mohsward4708 Год назад
just superb
@buombothmut
@buombothmut 6 месяцев назад
A great scientist ever❤
@jessicasmith6873
@jessicasmith6873 Год назад
I remember voting for pharmacology videos many months ago. I don't want to complain but I relied heavily on you to passing anatomy and now that I'm in pharmacology I'm gonna need you to hurry up 😜 . We did Parkinson medications last week 😞
@dailydoseofmedicinee
@dailydoseofmedicinee Год назад
Thanks
@owaisahmed7653
@owaisahmed7653 Год назад
outstanding all the time best teacher❤
@yosun_job
@yosun_job 2 месяца назад
Thanks doc
@PranamyaPednekar
@PranamyaPednekar 2 месяца назад
thank you so much
@solomebihon2218
@solomebihon2218 8 месяцев назад
you are great God bless you the best teacher ever am medical student in east Africa Ethiopia
@mrsamandabernier
@mrsamandabernier Год назад
Amazing 👏
@lucaspreafico7298
@lucaspreafico7298 8 месяцев назад
Thanks a lot for your work! What’s confusing to me is that i thought colinergic neurons were interneurons in the striatum
@zainabmaan5330
@zainabmaan5330 Год назад
You are amazing and vibrating
@user-hq2xw3dp7f
@user-hq2xw3dp7f Год назад
Thank you so much ❤❤❤❤
@virginiabruno624
@virginiabruno624 Год назад
You are intelligent you go deep into it
@timwillebrand2001
@timwillebrand2001 7 дней назад
amazing video
@azielmalili6516
@azielmalili6516 Год назад
You are a hero
@jamiefootball2409
@jamiefootball2409 Год назад
cutest tutor out there xx
@user-zx4mb3xv4p
@user-zx4mb3xv4p 9 месяцев назад
thanks a lot for the way of informations 😘😘😘😘😘😘
@deegallarupananda6927
@deegallarupananda6927 Год назад
Very useful
@zozoabdulkadir9642
@zozoabdulkadir9642 7 месяцев назад
You are amazing ❤
@moloreanm1657
@moloreanm1657 Год назад
Nice vid! Now one about Huntington’s 😊
@hadisehazizi3696
@hadisehazizi3696 6 месяцев назад
Thank you helping me with my pharma exam😭😭😭😭😭😭❤❤❤
@MomoCannonttv
@MomoCannonttv 10 месяцев назад
amazing
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