Pedigree Analysis methods - dominant, recessive and x linked pedigree

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Pedigree analysis by suman bhattacharjee - This lecture explains about the different rules of pedigree analysis. It explains how to find a pedigree based on characteristics with examples as dominant pedigree, recessive pedigree and x linked pedigree.
Dominant inheritance - affect shown in every generation
recessive inheritance - skips generation
X linked recessive trait - Male offspring are affected more.
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15 май 2016

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Комментарии : 356

@nabeelmusa722 5 лет назад

Attention please. Pedigree no 3 can be both x-linked recessive or autosomal recessive.. Very important to look again and again .. Both possibilities are applicable..

@pranjalkumar7693 4 года назад

Yes there is no any probability of x linked pass father to son but there is also a probability is that trait comes from mother...

@KJKP 4 года назад

At 15:55, Shomu says that, in X-linked recessive pedigrees, the trait NEVER transfers from father to son.

@enoch9019 4 года назад

Both can apply here

@enoch9019 4 года назад

@@KJKP but if both parents are affected, then the daughter is getting it from the affected father and the son is getting it from affected mother.

@liteducks 4 года назад

Because both father and mother are affected in the second generation, it is hard to discern whether the sons received the trait from mom or dad therefore allowing both autosomal recessive and x linked to be possible

@roshansharma2309 3 года назад

You are the first person who explain logic behind the topic

@shomusbiologyofficial 3 года назад

You're welcome. Glad to hear that you're getting benefit from my lectures

@over-pronouncedmayonaise3464 3 года назад

@@shomusbiologyofficial Yes!

@gajappriyavenkatachalam3197 4 года назад

Thank you very much sir, the way you teach the concepts is amazing

@bightonchinembiri 8 лет назад

two semester now gone, you have always been a life saver, keep up with the good work, brilliant videos there

@zainabqureshi9178 10 месяцев назад

Hey

@elisabethnoe5952 7 лет назад

I see you have professionalized your introduction. LOVE IT! I have been watching your videos for some time and am impressed with the direct, concise and thorough approach you take in your presentations. Your hard work is greatly appreciated and well loved by many students. Come visit MacEwan University Edmonton Canada!

@shomusbiologyofficial 7 лет назад

+Elisabeth noe thank you. It's a pleasure to help you out.

@Sona-yf4cl 2 года назад

Thank you so much sirr😍😍 from the past 3 -4 days I'm trying to understand pedigree but now at the time only I can understand the concept clearly with some golden rules .Now I can gain some extra marks in exam 😉

@shomusbiologyofficial 2 года назад

You're welcome. Glad you liked it

@varunazoologylecturer6387 8 лет назад

its make me to teach others very easily.thank u sir.

@stavshmueli6932 5 лет назад

For the third question, from the diagram you can deduce that it's either x-linked recessive or autosomal recessive. It's unsure which one of the two is correct though, need more information. Additionally, for the fourth question, it doesn't have to be x-dominant, there're other inheritance patterns that fit that pattern...

@Helloomi97 3 года назад

i also got that and i was so confused when he said it couldn't be x-linked recessive..

@sitthuson 3 года назад

Practice pedigree #2 and #3, I see it as being "Autosomal R" & "X-linked recessive"... The rules about skipping generation and male to female ratio don't entirely eliminate x-linked. those rules are not always reliable. Care to explain?

@cluelesshitchhiker1572 2 года назад

Ig the #2 is X-Linked Recessive

@ayishathulbareerasp4967 3 года назад

Sir i have a question: what is the purpose behind checking whether an autosome linked disorder is dominant or recessive using pedigree analysis?Is the treatment of autosome linked dominant disorder and autosome linked recessive disorder different?

@SB-wy2wx 4 года назад

The autosomal recessive pedigree's third generation: "sweet home Alabama"

@jaanvi6083 3 года назад

😂 u both go to evry video and say the same🙄😵🧐

@chelseaj5455 3 года назад

lol I just noticed that

@nandhiniv2218 3 года назад

@@jaanvi6083 yah 😂😂

@jaanvi6083 3 года назад

@@nandhiniv2218 i literally find this wtevr video i see yaar😩😴😒

@azeemsiddiqui3853 3 года назад

lmao besttttt

@almirapebryana2876 5 лет назад

thankyou so much. i have exam tommorow, after watch this video i understand this pedigree methods

@shomusbiologyofficial 5 лет назад

Glad it helped. Please share and subscribe

@SandeepKumar-nc9bm 6 лет назад

sir plz see again to question no 3 .It can also be x_linked recessive.

@varunazoologylecturer6387 7 лет назад

sir thank u very much for giving important message.

@rasmiranjanbehera4118 6 лет назад

So simple concept...tysm sir 🙏🙏🙏🙏🙏

@mayukhroy5393 4 года назад

-This video was very very helpful , Sir.

@KJKP 4 года назад

Problem #4 can be autosomal dominant. I think Shomu’s “golden rules” might be more like strong suggestions with frequent exceptions.

@backstreetfan2887 2 года назад

I agree

@ImALLENITE Год назад

Yes the 1st option is the correct BCOZ we have to take the left side also in our analysis 👍

@skeletortheskeleton1357 4 года назад

DUDE. IM CLOSE TO MIDTERMS AND THIS IS A LIFE SAVER. YOU ARE SO SMART. I LOVE YOU, THANK YOU!!!!!!!!!! KEEP IT UP!

@shomusbiologyofficial 4 года назад

Thank you. Glad you liked my lectures

@YouTubesucksman 2 года назад

Atlast got an explanation in English

@sehunnight4198 3 года назад

i spent a day a understanding my professors lecture about pedigree bcoz its included in my exam and i cant really understand it. and i watched your tutorial for the last minute, saw your vid and glad that u explain it well. now i can answer my exam later confidently. thank u so much. keep up the good work sir and keep safe. more power 💪🙌

@shomusbiologyofficial 3 года назад

Thank you so much for appreciating my efforts

@PrernaSharma-fb6pl 7 лет назад

Thank you so much! Ur videos are the best!

@moniko7503 7 лет назад

Thank you! This helped so much!

@07soumimondal91 4 года назад

Guitar

@sophiagarcia9018 3 года назад

@@07soumimondal91 please what does that mean LMAO

@shreeshdas4507 2 года назад

Thank you for uploading this video is very helpful

@shailendersingh3293 2 года назад

Yaa it's an nice outlook we can lay emphasis on x linked dominant if we see in the chart the ratio of transfer of disease from moter to son is more than father to daughter so it can be a x linked dominant

@Anne0718 3 года назад

great VIDEO. Thank u too much

@Yournightmare_435 8 месяцев назад

This is so helpful. Can’t thank you enough ❤

@shomusbiologyofficial 8 месяцев назад

You're welcome

@dkbhasinhealthcare 2 года назад

It very important topic study with logic clearly explained . Great sir, please explain Disease HAE ( heardetry Angioedema )

@sindhujavb8551 Год назад

Thank you Sir, for providing such a clear explanation.

@shomusbiologyofficial Год назад

You're welcome

@ramymelhem 7 лет назад

in the last example, could u not also say that it could also be due to an autosomal recessive condition? i mapped it out and it seems to work.

@Kaandhal-or3gu 21 день назад

It can never be recessive cuz its seen in all generations

@user-ep6ir5rf5j 2 месяца назад

Neet wale like button😂

@sherylmateva8777 Месяц назад

😂😂😂

@amairaniramirez8855 4 года назад

Live saver! Thank you!

@shomusbiologyofficial 4 года назад

You're welcome

@AnuragSjngh 6 лет назад

Thanks for this video it's is very good

@majidabdullah6598 Год назад

Sir with fue respect I want to know if the third problem solved is really autosomal recessive... Since in second generation the each of parents are coming from another family by considering that we can say that it's an x linked recessive trait. Correct me if I'm wrong. Thank you

@ANGELAAR 11 месяцев назад

Beautiful presentation ..concepts very concise❤

@shomusbiologyofficial 11 месяцев назад

You're welcome

@vaishnavijadhav101 3 года назад

thank you for such a nice explanation

@shomusbiologyofficial 3 года назад

You're welcome. Glad to hear that you're getting benefit from my lectures

@snigdhaaachi6066 5 лет назад

Thank you! Helped a lot.

@shomusbiologyofficial 5 лет назад

You're welcome

@pholososhamukuni9971 2 года назад

THANK YOU SO MUCH...REVISING AND GOING WELL❤

@shomusbiologyofficial 2 года назад

Thank you so much for appreciating my efforts

@Asianpotato77 7 месяцев назад

Random Indian guy explaining the exact thing i didn't understand coming in clutch

@shomusbiologyofficial 7 месяцев назад

All the best. BTW I'm not random Indian guy. It's Shomu from Shomu's Biology. The biggest reservoir of biology lectures in internet

@Aesthetic_fact69 Месяц назад

Thank you so much sir 😊...... You explained it very well... But I didn't understand last two pedigree charts According to me i think 2nd last is X-linked ressesive And the last one

@mr.abundant6449 6 лет назад

Thank you shomu bhai....

@Astralarius_Zenith 2 года назад

Thank you for this video! When we talked about this in class I was confused. Now I am having more clarity to the topic thanks to your video.

@shomusbiologyofficial 2 года назад

Thank you so much for appreciating my efforts

@esnh6372 2 года назад

Amazing video, thank you so much!!!!!!!!!

@shomusbiologyofficial 2 года назад

You're welcome

@shubhamsinghbartwal2028 4 года назад

In pedigree 3 in case of affected father do not pass traits to their son. But sons can be affected by affected female.. But affected sons can come from affected mother, and affected female can come from affected father... Why not x linked recessive or dominant...

@user-ll6td7nl3f 3 года назад

i love you. you saved my midterm exam :)

@shomusbiologyofficial 3 года назад

Thank you

@sthelilesihle5102 8 месяцев назад

Sir, when looking at individual 7&8, could we say it's autosomal dominant because the trait didn't skip the generation?

@zooharafique6677 3 года назад

ThankYou! For this helping video ❤i didn't understand ever about these conditions of pedigree, but i must say after i saw this i can easily solve my all questions related to these four traits... 🌸🌸✨✨✨

@avneetkamboj6219 2 года назад

Very helpful video for understanding pedigrees

@shomusbiologyofficial 2 года назад

You're welcome

@rscreativevideo5417 4 года назад

Shomu sir today I have answered all question except one from pedigree .It is all because of you.U r really god of biology.No words to say about u.soulful thanks from tamilnadu

@lewisbeard8105 6 лет назад

Number 2 looks more like a case of Autosomal Dominant with reduced penetrance?

@daxaprajapati6581 3 года назад

Thank u so much

@sahildhull2662 8 лет назад

thankyou very very very much...... sved my genetics exam.......

@shomusbiologyofficial 8 лет назад

+Sahil Dhull thank you

@jishavinukumar1412 2 года назад

Thank you sir for taking the class in English

@shomusbiologyofficial 2 года назад

You're welcome

@nnyadav5595 7 лет назад

hey in this video there is five female are affected,and only four males are affected.how can this problem is autosomal? there is no 50-50 chance of both male and female being affected

@bhatyasin2244 5 лет назад

Problem No. 3 follows x linked recessive inheritance...I have checked genotypically... Please remove the confusion

@FlatDrifting265 Год назад

this was taught better than my teacher. thank you.

@shomusbiologyofficial Год назад

You're welcome

@shikhadwivedidwivedi9869 3 года назад

Please sir clear a doubt in A-R if assume three offspring then is it possible one offspring disease affected and other two not

@indhuunni5181 4 года назад

Is congenital defness of 2 son from normal parents a AR inheritance

@lukelingo9181 3 года назад

i have a question for the fourth pedigree in the second generation dosen't the daugther also get affected even tho the father isn't dosen't that mean the daugther is affected from the mother but isn't that like impossible if it's meant to be x linnked

@12hmbkjayant72 26 дней назад

TOTAL BANGER EXPLANATION

@shomusbiologyofficial 25 дней назад

Thank you

@gamingid648 4 года назад

Very helpful keep going on bro❤️🙏❤️

@shomusbiologyofficial 4 года назад

You're welcome. Glad to hear that you're getting benefit from my lectures

@theorange8755 4 года назад

Wonderful thank you

@shomusbiologyofficial 4 года назад

You're welcome

@moelol7113 3 года назад

Hello from 2021, 18:04 sir this pedigree can work as sex-linked recessive

@mahaavtarbabajineebkarolibaba 2 года назад

exellent explaination... wow amazing

@shomusbiologyofficial 2 года назад

Thank you

@katsanlavers 2 года назад

Вау, это очень круто! Спасибо

@nicoleviloria5184 3 года назад

This is the first time I get it!!

@chepkorirvicky7558 4 года назад

You the best, I had to subscribe❤

@shomusbiologyofficial 4 года назад

Thank you. Glad you liked my lectures

@chetnamittal7126 7 лет назад

o have a confusion that how can a trait be autosomal if more no of female are suffering from a disease

@IM-bc3tm 5 лет назад

Vary helpful thank you(:

@shomusbiologyofficial 5 лет назад

You're welcome

@anilkumarsharmazoology8333 4 года назад

Thank you so much

@shomusbiologyofficial 4 года назад

You're welcome

@hridaybaruah Год назад

I THINK THE PEDIGREE AT 14:22 CAN ALSO BE EXPLAINED BY X-LINKED RECESSIVE DISEASE. WORKING OUT THE GENOTYPES MAKES IT LOOK LIKE A COMPLETELY PLAUSIBLE ANSWER. PLEASE DO CONSIDER IT ONCE AND I MAY BE WRONG BUT COULD YOU PLEASE EXPLAIN, ITS REALLY CONFUSING ME

@emmanuelchipeta1622 Год назад

It really has helped 💓 thank you

@shomusbiologyofficial Год назад

You're welcome

@jenvipatel5541 2 года назад

Thank you! This video helped me understand the 4 different types of pedigrees for my biology exam!

@shomusbiologyofficial 2 года назад

You're welcome

@GunjanR516 2 года назад

Janvi Or jenvi?

@shafiahmadtalukder3543 5 лет назад

no 3 is confusing sir,please recheck this

@sakola4 Год назад

Brother, today is my exam. Wish me luck. Thank you brother!

@shomusbiologyofficial Год назад

All the best

@themadladprince430 2 года назад

15:05, I don't understand why it would be a form of dominance. If both the parents were reccessive, then by crossing rr x rr, all the progeny are affected. Can someone please explain to me why it is a form of dominance?

@poojagaddam3646 2 года назад

Sir what is meant by Raw and forked pedigree . please give me rply

@abhishekpatel7335 6 лет назад

thanks.

@sangyunlee9243 Год назад

Can problem 3 be xlinked recessive? because Gen 2-4 female is a career XA Xa.

@mersijaalic3045 7 лет назад

You have explained it well, but i think that you should have written genotypes for each person. In that way we could see if we did the excercises well (3. and.4. exp). :)

@manojmanly1057 6 лет назад

Nice explanation

@philippeter198 3 года назад

very helpful

@ashleyc1339 2 года назад

I have a human hereditary mid term tomorrow… thank you!

@shomusbiologyofficial 2 года назад

Thank you

@tinkeshpatidar3881 2 года назад

Sir last wale quastion me outsider ko Carrer assume karna pad raha h......jo galat h.... Outsider ko humesha healdy male he manna padaga..... So x link ressesive padigree hogi last wale quastion me

@rosaundra_eugenia 4 года назад

In pedigree example 2 there are 5 females affected and 4 males affected, or am I wrong? Secondly, In pedigree number 3, couldn’t it be distinguished as autosomal recessive because 2 unaffected parents have an unaffected child on the left side and also because 2 parents have all affected children on the right side? Why is the right part where 2 affected parents have all affected parents identified as autosomal dominant?

@nouraalmousa4958 4 года назад

Salam , how are you ? ….. may I ask you please the Fragile X syndrome fall under which Inheritance PatternX-linked Recessive or Dominant (or both)?

@zainabqureshi9178 10 месяцев назад

Walekumsalam

@gautomibasumatary5478 4 года назад

Thank you sir.

@shomusbiologyofficial 4 года назад

You're welcome. Glad to hear that you're getting benefit from my lectures

@asuramunikavishadesilva371 5 месяцев назад

thank you so much sir!❤

@shomusbiologyofficial 5 месяцев назад

Most welcome!

@badtameezdil3119 7 лет назад

Helpful

@user-ow9oz4pp4i 2 года назад

Your voice is soo sweet pleasant to hear bro🤘❤️

@shomusbiologyofficial 2 года назад

Thank you

@joseluisboffillborroto5407 2 года назад

Podría usted hacer la traducción de ese análisis del pedigree en idioma español?

@dkbhasinhealthcare 2 года назад

With explain how to control HAE disease

@asfa9039 3 года назад

6:47 Are the lines written in the chart always validate???

@user-og8pl5tk1i Год назад

2023 and this video is helping me. Shout out to You

@shomusbiologyofficial Год назад

Thank you

@ranjani4899 7 лет назад

simply nice and understandable..

@shomusbiologyofficial 7 лет назад

+Prathisha Ranjani thank you. Glad you liked my lectures

@praveengoel6136 6 лет назад

The explanation was excellent and worth seeing.

@sohailshaikh6735 2 года назад

Thank You Sir

@shomusbiologyofficial 2 года назад

You're welcome

@mrraj9463 Год назад

How we analys relatives pedigree chart

@sahilrampal5723 3 года назад

Very helpful

@shomusbiologyofficial 3 года назад

Thank you

@yuvarajgalagali3439 3 года назад

Best explanation with best examples ❤️

@shomusbiologyofficial 3 года назад

Thank you so much for appreciating my efforts

@ericstevens7738 3 года назад

The right side of the third pedigree does not help elucidate autosomal recessive vs X-linked recessive. Granted, with two affected females in the same family from different bloodlines, it is probably more likely to be AR inheritance. We would need prevalence to weigh this speculation. However, using binomial statistics and the pedigree at hand, it is statistically speaking more likely X-linked recessive inheritance. Probability of getting the outcome of individuals 4,5,6,7 for AR = 0.09375 Probability of getting the outcome of individuals 4,5,6,7 for XR = 0.37500 Probability of getting the outcome of individuals 9,10,11,12 for AR = 0.140625 Probability of getting the outcome of individuals 9,10,11,12 for XR = 0.187500 This example was poor as it does not offer new students a concrete way to identify an inheritance pattern. Best of luck!

@backstreetfan2887 2 года назад

amazing, thank you